Rosa Damascene Research Articles

Phytochemical Screening of Valuable Polyphenol Compounds and Essential Oil Profile of Three Rosa damascene Genotypes, as an Important Plant for Medicine and Food Industry

Phytochemical Screening of Valuable Polyphenol Compounds and Essential Oil Profile of Three Rosa damascene Genotypes, as an Important Plant for Medicine and Food Industry

Effect of inhaled aromatherapy on sleep quality in critically ill patients: A systematic review and network meta-analysis.

This study aimed to compare the effect of inhaled aromatherapy using various essential oils on the sleep quality of critically ill patients. Inhalation of essential oils significantly promotes the physiological and psychological health of patients in intensive care units (ICUs). However, research identifying and ranking the effects of different essential oils on the sleep quality of critically ill patients is lacking. This study followed the PRISMA Extension Statement for Reporting of Systematic Reviews Incorporating Network Meta-Analyses of Health Care Interventions (PRISMA-NMA) guidelines. A comprehensive search of five databases (Embase, MEDLINE, the Cochrane Library, CINAHL and PsycINFO) was conducted from their inception to March 15, 2023 (with an additional eligible study included dated August 14, 2023). Google Scholar was used as a supplementary method. Frequentist NMA was used to determine the effects of various essential oils. Certainty of evidence (CoE) was assessed using Confidence in Network Meta-Analysis (CINeMA). A total of 11 trials involving 690 critically ill patients were included in the analysis. The NMA of inhaled aromatherapy revealed that the combination of lavender, Matricaria recutita, and neroli essential oils (ratio 6:2:0.5) resulted in the most significant improvement in sleep quality compared to usual care, followed by Rosa damascene, peppermint, Citrus aurantium, pure sunflower oil and lavender oil alone. The overall CoE for the results was rated as low. The results of this study indicate that a combination of lavender, Matricaria recutita and neroli essential oils significantly positively affected sleep quality among critically ill patients. Despite the low quality of evidence, inhaled aromatherapy is non-invasive and easy to use. Inhaled aromatherapy can effectively improve sleep quality among critically ill patients. No patient or public contribution applies to this work. The study protocol was registered to the PROSPERO International Prospective Register of Systematic Reviews (protocol number CRD42023433194).

Capturing the antimicrobial profile of Paeonia officinalis, Jasminum officinale and Rosa damascene against methicillin resistant Staphylococcus aureus with metabolomics analysis and network pharmacology

In the current study, we evaluated the in vitro antibacterial efficacy of the roots’ extracts of Jasminum officinale, Rosa damascene and Paeonia officinalis against MRSA (methicillin-resistant Staphylococcus aureus) by well diffusion technique. The root extract of P. officinalis exerted a potent anti-MRSA with MIC 0.4673 µg/ml, while both J. officinale and R. damascene exhibited very weak activity. Therefore, chemical profiling of the crude extract P. officinalis roots assisted by LC-HR-ESI-MS was performed and led to the dereplication of twenty metabolites of different classes, in which terpenes are the most abundant compounds. On a molecular level, network pharmacology was used to determine the targets of active metabolites to bacterial infections, particularly MRSA. Online databases PubChem, UniProt, STRING, and Swiss Target Prediction were used. In addition to using CYTOSCAPE software to display and analyze the findings, ShinyGO and FunRich tools were used to identify the gene enrichment analysis to the set of recognized genes. The results detected the identified metabolites were annotated by 254 targets. ALB, ACHE, TYMS, PRKCD, PLG, MMP9, MMP2, ERN1, EDNRA, BRD4 were found to be associated with MRSA infection. The top KEGG pathway was the vascular smooth muscle contraction pathway according to enrichment FDR. The present study suggested a possible implication of P. officinalis roots as a potent candidate having a powerful antibacterial activity against MRSA.

Chemical, electrochemical, and surface studies of Rosa damascene extract as a green corrosion inhibitor for carbon steel in sulfuric acid environment

AbstractTo develop an environmentally acceptable corrosion inhibitor Rosa damascene extract (RD) served as the main ingredient in H2SO4 pickling processes. X‐ray photoelectron spectroscopy (XPS), Fourier‐transform infrared spectroscopy (FT‐IR), technique of electrochemical impedance spectroscopy (EIS), polarization (PP) curves, and tests of weight loss (WL) have all been utilized to examine the inhibitory behavior of Rosa damascene on C‐steel corrosion in 1 M H2SO4 environment. The results show that the extract effectively inhibited the Zn′ corrosion in 1 M H2SO4. The inhibition was more effective at higher concentrations and temperatures. The inhibitory efficiency increased to 93.5% at a higher applied temperature (45°C) and higher Rosa damascene concentration (300 ppm). However, utilizing the weight loss method at potassium iodide addition, the inhibitory effectiveness of 300 ppm of Rosa damascene was synergistically increased from 75.0% to 96.1% at 25°C. Temkin isotherm was congruent with the adsorption process that produced the inhibitory impact on the C‐steel. The chemical adhesion of the Rosa damascene extract to the surface of the C‐steel was determined by the free energy of adsorption (ΔGoads = 40.5 kJ/mol.). In H2SO4 solution, corrosion of C‐steel may be prevented by the powerful inhibitor Rosa damascene extract.

Phytochemical Compositions and Cosmeceutical Activities of Rosa damascena Mill. Leaf Extracts from Environmentally Friendly Extraction Technique

A significant amount of Rosa damascena Mill. leaves were discarded as waste during the harvesting and pruning for flowering. The current study aimed to investigate the potential of using these agricultural waste products in the cosmetics industry. Dried R. damascena leaves were extracted using maceration or environmentally friendly extractions, including infusion, digestion, ultrasonic, microwave, micellar, and pulsed electric fields (PEF) extraction. The extracts were analyzed for their chemical compositions and assessed for antioxidant, anti-tyrosinase, and anti-aging properties. The irritation profile of each extract was investigated by the hen’s egg-chorioallantoic membrane (HET-CAM) test. The results noted that extraction by ethanol yielded significantly higher extract content than deionized water (P < 0.05). However, total phenolic and flavonoid content was found to be greater, whereas the bioactive compounds, including rutin and rosmarinic acid, were only found in the aqueous extracts. On the other hand, kojic acid was found in the extract from infusion and maceration. Interestingly, the extracts from micellar and PEF extractions were found to significantly scavenge the radical, which were related to their rutin contents. Their collagenase inhibition (69.1 ± 10.1% and 54.8 ± 19.1%, respectively) were equivalent to those of epigallocatechin gallate, a well-known anti-aging compound (76.0 ± 1.2%). Besides, all extracts were safe since they induced no irritation in the HET-CAM test. In conclusion, environmentally friendly extraction of bioactive components from R. damascena leaves were suggested, with the potential to be exploited as an anti-aging and whitening ingredient for further use in cosmeceutical area. Keywords: Rosa damascene, Green extraction, Antioxidant, Anti-tyrosinase, Collagen, Elastin; Hyaluronan, Irritation

Search for the Natural Remedies for the Treatment of Dry Cough

Search for the Natural Remedies for the Treatment of Dry Cough

Antibacterial activity of Rosa damascene petals mill extracts

Infectious diseases are one of the major common problems facing the world. Staphylococcus aureus and Escherichia coli are two causes of infectious diseases and are considered as multi drug resistance pathogens. There is a continuing need for the discovery of new agents to overcome antibiotic resistance. Plants used in traditional medicine comprise several components which can serve as alternative candidates. Of these components, phenolic compounds, a secondary plant metabolite, account for antibacterial activity of many plants. Rosa damascena, traditionally used for its several therapeutic properties, is highly rich of phenolic compounds. In this in vitro study, aqueous and ethanolic extracts of the Rosa damascene petals mill were prepared and the phenolic content was determined. The extracts were tested for antibacterial activity using the disk diffusion method and the broth microdilution method for MIC determination. The extracts were able to inhibit the growth of studying pathogens. Staphylococcus aureus was more sensitive to Rosa damascena aqueous extract with a MIC of 0.28×103µg/ml and inhibitory zone of 17.33±0.85mm. On the contrary, Escherichia coli was more sensitive to Rosa damascene ethanolic extract with a MIC of 0.2×103µg/ml and inhibitory zone of 16.33±1.15mm. The results suggest the antibacterial activity of the Rosa damascena mill.

DNA Barcoding Based Identification of Rosa x Damascene and Prunus dulcis Herbs Using ITS2 Barcoding Gene Amplification.

The considerable risk of adulteration in the herbs has raised commercial interest in the identification of medicinal herbs globally. DNA barcoding is the primary techniques for identifying the herbs at genetic level. This technique's key benefit is that it can identify the material's purity. This study focuses on the accurate identification of species utilizing Polymerase chain reaction-based nuclear universal internal transcribed spacer region (a barcode region) amplification and sequencing in 2 medically significant plants (Rosa damascene and Prunus dulcis) procured from the local herbal market of Karachi in the year 2022. Results suggest that the ribosomal nuclear ITS2 region of the selected plant species shows the 100 % identity with the reference genome, therefore it has shown a good rate of identification at the species level. The findings of this concludes that ITS2 is the novel standard barcode that involve in species identification, genomic conservation, and secure utilization of the medically significant plant species.

Ultrasound-assisted extraction with natural deep eutectic solvent for phenolic compounds recovery from Rosa damascene Mill.: Experimental design optimization using central composite design

Combining natural deep eutectic solvents (NADES) and ultrasonic-assisted extraction (UAE) created a green extraction medium for important phenolic compounds recovery from Rosa damascene Mill. For this purpose, three different NADES based on lactic acid were designed and tested as green extraction solvents. Citric acid, glucose, mannitol, and glycerol were used as hydrogen bond donors (HBD), while lactic acid as a hydrogen bond acceptor (HBA). The best extraction efficiency was demonstrated by NADESLACAGLY, which contains lactic acid, citric acid, and glycerol (3:1:2) compare with two other NADES (NADESLAGLU and NADESLAMA) and conventional solvents (ethanol and methanol). These parameters included total phenolic compounds (TPC), total flavonoid compounds (TFC), and antioxidant activity (AA). Then the UAE procedure was optimized through response surface methodology (RSM) using central composite design (CCD). Quadratic models produced a satisfactory fitting of the experimental data with regard to total phenolic compounds (R2 = 0.9625, p < 0.0001 and p < 0.05), total flavonoid compounds (R2 = 0.9682, p < 0.0001 and p < 0.05), and antioxidant activity (R2 = 0.9940, p < 0.0001 and p<0.05). An extraction time of 60 min, a solvent volume of 35 mL, and an amount of water in NADES 30 % (v/v) were considered optimal conditions. The present study demonstrates the potential for creating eco-friendly solvents with enhanced extraction capabilities compared to organic solvents for the extraction of bioactive compounds from various natural sources that are used as natural food colorants and cosmetic dyes.

Empowering Cihideung Village Farmers in Using Rose Flowers as Pharmaceutical Raw Materials

Roses (Rosa Damascene Mill) are the most prominent crops of the Cihideung Village community. During the COVID-19 pandemic, flower farmers needed help with marketing, so many of the roses were unused. These empowerment activities aim to increase the public's knowledge and capacity to use roses as a pharmaceutical. The activities are carried out offline in the form of workshops. The raw materials are fresh rose flowers, tools, ingredients for making rose water infusions, soap, and oil. Analysis of outcome was assessed using questionnaires before and after the workshop as well as observation of the enthusiasm of participants during the activity. The results showed an improvement in the knowledge and skills of the public regarding the use of roses. The community also provided guides for the improvement of their capacity independently and access to the technical video through YouTube. Activity publications are delivered in digital media as a promotion. The full support of the provincial government and local villages will strengthen the synergy and sustainability of these activities, and hopefully, in the future, this knowledge can improve and become an independent enterprise of the community of Cihideung Villages.

Response of Two Rosa sp. to Light Quality in Vitro.

In this study, dark and various light qualities (white, red, green, and blue) were applied to evaluate their effects on growth characteristics, chemical content, and callus characteristics of Rosa damascene Mill. and Rosa hybirda L. Explant (single-node and shoot tips) cultured on MS media supplemented with sucrose, agar, and plant growth regulators ( Kin 0.5 mg/l and IBA 1 mg/l for whole plant formation experiment or 1 mg/l kin with 0.5 mg/l IBA for callus experiment), incubated in a growth chamber. The results of the whole plant formation experiment showed variation in growth characteristics in two types of Rosa, Green and white light caused the height ratio of shoot growth compared with dark, while red and green light caused the height ratio of root growth to compare with dark. Rosa growing in white or green has a higher content of chlorophyll, as well as carbohydrates and proteins in shoot and root parts compared with dark. The results of the callus experiment explained variation in callus characteristics (shape, texture, color, and weight), the highest fresh weight (1.83 and 1.99) gm and dry weight (0.207 and 0.233) mg of callus Rosa damascene and Rosa hybirda, respectively in dark conditions compared with least in blue light.

Antioxidant Activity of Rose Tea (Rosa damascene) with Various Types of Sugar and Rose Tea Concentration

Kombucha tea is a traditional beverages product manufactured from fermented tea and sugar solutions. Using Acetobacter xylinum sa starter. Kombucha tea has a refreshing sour taste, but the distinctives aroma make kombucha tea less attractives to consumers. Red roses (Rosa damascene) are a source of anthocyanin pigments that have not been widely used. In addition, to increase the economic value of roses. Based on research that has been done, red roses contain antioxidants in the form of purplish red anthocyanins. The purpose of this study was to determine the effect of the type of sugar and the concentration of rose extract on the characteristics of rose kombucha produced. This study used Completely Randomized Design (CRD). The factors used were the concentration of rose tea (1g/250ml, 2g/250ml, 3g/250ml) and variations in the type of sugar (palm, sand, fine). The best chemical and organoleptic analysis based on the highest antioxidant activity was the addition of palm sugar and the concentration of the addition of rose tea 1g/250ml with a total phenolic of 10.17mg GAE/L, total dissolved solids (TPT) 11.10%, acidity (pH) 3.86, antioxidant activity 48.28%, vitamin C 11.41%, 13.63% for total sugar, sour taste score 3.06, rose flavor 2.15 and 1.10 for overall preference the addition of palm sugar and the concentration of the addition of rose tea 1g/250ml. Kombucha made from rose extract can be an alternative functional food.

Efektivitas Aromaterapi terhadap Kualitas Tidur dan Kecemasan

This study aims to determine the effectiveness of aromatherapy on sleep quality and anxiety in elderly adult population patients. The method used is a systematic review related to the management of sleep disorders and anxiety with aromatherapy. The results showed that aromatherapy given by inhalation and massage methods with lavender, rosa damascene, chamomile and neroli essential oils for at least three nights and a maximum of thirty days was considered to have an effect on sleep quality and anxiety. Conclusion, aromatherapy is effective in improving sleep quality and reducing anxiety. &#x0D; Keywords: Anxiety, Aromatherapy, Sleep Quality

Protective Role of Rosa damascena Miller hydroalcoholic extract on Oxidative Stress Parameters and Testis Tissue in Rats Treated with Sodium Arsenite

Regarding the strong antioxidant properties of Rosa damascene extract, this study aimed to investigate the protective role of Rosa damascene Miller hydroalcoholic petal extract on oxidative stress parameters and testis tissue in rats treated with sodium arsenite. To this end, 30 male rats were divided into five groups, including control, positive control (treated with arsenite), and three groups of patients affected by sodium arsenite with 150 mg/kg, 300 mg/kg, and 450 mg/kg Rosa damascene extract for 34 days by gavage. The animals were then anesthetized, and the blood samples were collected from the heart. The left testis was removed for histopathological studies. The findings revealed that Sodium arsenite in the positive group caused a significant reduction in TAC, testosterone, and serum Luteinizing hormone (LH) and a significant increase in serum Malondialdehyde. In addition, there was no statistically significant difference among the groups regarding the amount of Follicle-stimulating hormone (FSH). Moreover, the consumption of Rosa damascene extract with sodium arsenite caused a significant increase in testosterone, LH, and FSH compared to the positive control group. Histopathological results showed that in the experimental group receiving a dosage of 300 mg/kg b.w and the control group, the number of sperm tubes increased, and the germinal epithelium’s thickness was appropriate. Daily treatment with Rosa damascene extract with a dosage of 300 mg/kg b.w for 34 days could improve the changes caused by sodium arsenite and reduce Malondialdehyde levels. Thus, it seems that Rosa damascene hydroalcoholic extract can effectively improve the male reproductive system’s function.

HIGH NPK SOLUTION AND PGP IMPROVED EOS PROPERTIES OF ROSE GROWN IN COCOPEAT

This research was carried out at Research Station , Department of Horticulture and Landscape Engineering , College of Agricultural Engineering Sciences , University of Baghdad during fall season of 2020, it was aimed to improve flower productivity, quantity and quality of essential oils with increasing the concentration of N, P , K elements in the nutrient solution, and foliar app `lication of Plant growth promoters (PGP) on Rosa Damascene grown on a soilless culture system with coco peat substrate bags. A factorial experimental design was carried out according to (RCBD)with three replication. Results indicated the superiority of a high nitrogen treatment and 1.5 g of PGP (N2S2 ), of the flowers number, dry matter%, flower diameter, oil quantity and all physical and the anatomical characteristics, represented by the diameter of the head diameter of the glandular capillaries. Petals number increased significantly with a high potassium nutrient solution and PGP 1 g (N4S1).The high phosphorous solution, which was not treated with growth stimulator, showed superiority in the length of glandular capillaries.

Anti-microbial efficacy and notable biocompatibility of Rosa damascene and Citrus sinensis biomass-derived metabolites

Anti-microbial efficacy and notable biocompatibility of Rosa damascene and Citrus sinensis biomass-derived metabolites

The effect of rose oil aromatherapy and hand-holding on pain due to peripheral intravenous catheter insertion

IntroductionThe study aimed to evaluate the effectiveness of rose oil (Rosa Damascene Mill.) aromatherapy and hand-holding in reducing pain associated with peripheral intravenous catheter insertion. MethodsA comparative mixed-method design. A total of 126 patients were included in the study. For the study's quantitative data, sociodemographic characteristics of the patients and the Patient Interview Form for the qualitative data of the Numeric Rating Scale were used. In all patients included in the study, PIVC insertion was performed a single time by the same nurse using a standard procedure. Chi-square and Bonferroni tests were used for comparative statistics. ResultsNo statistically significant difference between the groups regarding age, gender, marital status, BMI, and education level (p>0.05). Pain scores: it was 2.40±1.78 in the rose oil group, 3.53±1.98 in the hand-holding group, and 4.88±1.56 in the control group. The difference between the groups regarding pain scores is statistically significant (p=0.001). ConclusionsThe study determined that rose oil aromatherapy and hand-holding interventions reduce pain during PIVC. However, rose oil aromatherapy was more effective on pain than the hand-holding intervention.(Clinical Trial ID: NCT05425849)

Effects of aromatherapy with Rosa damascene and lavender on pain and anxiety of burn patients: A systematic review and meta-analysis.

Pain and anxiety were considered the most common complications of treatment procedures in burn patients. Non-pharmacological drugs, including aromatherapy, can decrease these issues. This systematic review and meta-analysis aim to summarise the effects of aromatherapy with Rosa damascene (RD) and lavender on the pain and anxiety of burn patients. A systematic search was performed on international electronic databases such as Scopus, PubMed, and Web of Science, as well as on Iranian electronic databases such as Iranmedex and Scientific Information Database (SID) with keywords extracted from Medical Subject Headings such as "Burns", "Pain", "Pain management", "Anxiety", and "Aromatherapy" were performed from the earliest to November 1, 2022. The Joanna Briggs Institute (JBI) critical appraisal checklist assessed the quality of randomised control trials (RCTs) and quasi-experimental studies. STATA v.14 software was used to estimate pooled effect size. Heterogeneity was assessed with I2 value. Random effect model and inverse-variance method using sample size, mean, and standard deviation changes were applied to determine standard mean differences (SMD). The confidence interval of 95% was considered to determine the confidence level. A total of 586 burn patients participated in six studies, including three RCT studies and three quasi-experimental studies. The results based on RCT studies showed RD significantly decreased the dressing pain average when compared to the control group (SMD: -1.61, 95%CI: -2.32 to -0.99, Z=5.09, I2 : 66.2%, P< 0.001). Aromatherapy with lavender decreased the average pain in the interventional group more than in the control group (SMD: -1.78, 95%CI: -3.62 to 0.07, Z=1.89, I2 : 97.2%, P= 0.06). Using aromatherapy with RD and lavender significantly decreased pain average in the interventional group than the control group (SMD: -1.68, 95%CI: -2.64 to -0.72, Z=3.42, I2 : 94.2%, P= 0.001). The results showed RD significantly decreased the anxiety average in the interventional group than the control group (SMD: -2.49, 95%CI: -2.98 to -2.0, Z=9.94, I2 : 51.6%, P< 0.001). Overall, this study showed that aromatherapy with RD decreased pain and anxiety of dressing procedures in burn patients. Although aromatherapy with lavender decreased pain in the patients, it was not statistically significant. More RCTs studies are required to be able to better judge the effects of aromatherapy with RD and lavender on the pain and anxiety of burn patients.

MEDICAL EFFECTS OF PRODUCTS OBTAINED FROM WILD ROSE PLANT

Except for one tropical African species, the Rosa L. species (roses; Rosoideae: Rosaceae) has 150–200 species that are extensively dispersed throughout temperate and subtropical ecosystems of the northern hemisphere. The fact that Central Asia is the rose's native continent is underlined in numerous sources. A quarter of the rose species are found in Europe and North America, while nearly half are found in Asia. Rosa damascene Mill is the species utilized to obtain rose oil, even though there are 24 types of roses registered in Turkey's flora. Rosa damascene, also referred to as the Damascus Rose, Pink Oil Rose, Oil Rose, and Isparta Rose Rose is a perennial, thorny, intensely perfumed, pink-hued, half-layered, and winter-hardy shrub that only blooms in the spring. The range of products is also increasing due to the demand for roses and rose products in this sector. Many products are being developed in the field of nutrition, cleaning, and cosmetics. The aim of this study is to investigate the effects of wild rose plants in the field of health and to expand their use. However, it is thought that increasing the variety of products obtained from the wild rose plant may contribute to the country's economy. The aim of the study is to investigate the use of wild rose plant in our country and in other countries, to show in which diseases it is used and to determine its contribution to the economy of the countries.

Comparative Phytochemical Analysis and Mineral Profile of Rosa damascene and Rosa centifolia

The present study was mainly focused to analyse the phytochemical, biochemical quantification and mineral profile of dried rose petals of Rosa damascena and Rosa centifolia. The Quantitative analysis of carbohydrates, protein, phenol and the qualitative phytochemical analysis were carried out in aqueous and ethanolic extract of Rosa damascena and Rosa centifolia petals using the standard procedures. From the present study it can be interpreted that the preliminary phytochemical analysis of the aqueous and ethanolic petal extract of Rosa damascena showed positive results in many tests namely carbohydrate, protein, flavonoid, glycosides and alkaloids. Nutrient composition of the dried rose petals of R. damascene and R. centifolia contain carbohydrate, protein and phenol. The highest amount of carbohydrate (448.70 mg GL /gm), Protein (312.33mg BSA/gm) and phenol (287.42 mg GAE/gm) were observed in Rosa damascene and the lowest amount of carbohydrate (100.22 mg GL /gm), Protein (170.17mg BSA /gm), and phenol (245.45mg GAE/gm) were observed in Rosa centifolia. Mineral profile of the following parameters such as Nitrogen, Potassium, Calcium, Magnesium, Chloride, Iron, Sodium, Sulphate were determined and quantified. In conclusion, the presence of nutrients was considered to be the first biochemical quantification that reports the major nutrients of carbohydrates, proteins and phenol and some minerals in the dried rose petals of Rosa damascene and Rosa centifolia that can be strongly recommended for human diet intake.