In this work, we study the degree-based topological invariants, and the general sum-connectivity, A B C 4 , G A 5 , general Zagreb, G A , generalized Randić, and A B C indices of the line graphs of some rooted product graphs ( C n { P k } and C n { S m + 1 } ) are determined by menas of the concept of subdivision. Moreover, we also computed all these indices of the line graphs of the subdivision graphs of i-th vertex rooted product graph C i , r { P k + 1 } .