The article presents the results of studies on the introduction of manure, straw and intermediate green manure in a grain-grass crop rotation against the background of the introduction of calculated doses of mineral fertilizers on the gray forest soil of the Republic of Tatarstan. The results of studies showed that options with the introduction of manure and plant biomass reduced the soil density in the 0-10 cm layer by 0.02-0.04 g/cm3, in the 10-20 cm layer by 0.03-0.04 g/cm3. The total content of structural aggregates in the variants with the introduction of manure and the joint incorporation of straw and green manure increased to 46.7-72.9%, the structural coefficient was 0.87-2.69, against 44.3-63.9% and 0.79 -1.77 on the mineral background. The amount of crop and root residues that came into the soil after harvesting perennial grasses more accumulated in the backgrounds with the addition of manure, straw and green manure and amounted to 10.8-12.1 tons per hectare, while the mineral background made up only 10, 11 tons per hectare. Against the same background, an increase in the content of humus in the soil by 0.12-0.16% occurred. Improving the soil fertility of the soil, manure, straw and green manure contributed to an increase in crop yields in crop rotation compared with the mineral background: winter rye by 0.2-5.0 centner, spring wheat by 1.2-6.8 centner, perennial grasses by 1.2-7.3 grain units, spring wheat – 2.5-5.4 centner, oats - 2.4-5.3 center per hectare. Crop cultivation in a grain-grass crop rotation on the background of the combined application of straw and crop green manure made it possible to get a maximum profit of 22,835.6 rubles per ha with a profitability level of 162.8%, against 15540.0 rubles per ha and a profitability of 96.4% against a mineral background.