Case 1. A 58-year-old man was scheduled for right middle lobe lobectomy to remove a lung tumor. He previously had a cystectomy and an iliac conduit for bladder cancer and left pneumonectomy for lung cancer. After left pneumonectomy, respiratory function data showed forced vital capacity (FVC) was 3.14 L (82.8%) and forced expiratory volume at 1 second (FEV1.0) was 1.74 L (53.6%). Breathing room air, blood gas analysis showed pH 7.392; PaO2, 80.9 mmHg; PaCO2, 44.5 mmHg; SaO2, 96.3%; and base excess, 1.7 mEq/L. After placement of an epidural catheter at T5-6, anesthesia was induced with 3 mg/kg of thiopental followed by 0.15 mg/kg of vecuronium. To use the bronchial blocker of a Univent tube (Fuji Co Ltd, Tokyo, Japan) as an independent blocker, the authors detached it from a Univent tube. The bronchial blocker initially was introduced into the trachea, after which the patient was intubated with a standard 9.0-mm internal diameter tube. The bronchial blocker was used outside the endotracheal tube. After this, radial artery and right internal jugular vein catheters were placed. Arterial blood gases were continuously monitored by a Paratrend7 (Biomedical Sensors Ltd, High Wycombe, UK). Anesthesia was maintained with fentanyl, isoflurane and oxygen, and epidurally administered 1% lidocaine. Fig 1 shows the changes in PaO2 and PaCO2 during the operation. Guided by fiberoptic bronchoscopy, initially the blocker was advanced to the bronchus intermedius, and the middle and lower lobes were collapsed, but PaO2 rapidly decreased and PaCO2 continued to increase. The authors then ventilated the whole lung and tried to block the middle lobe. This was successful, allowing normocapnia to be maintained throughout the operation with PaO2 at 80 mmHg. Collapse of the middle lobe also provided adequate surgical exposure and facilitated surgical procedures. When the middle lobe bronchus was stapled, ventilation was transiently stopped, and the blocker was withdrawn. Middle lobe lobectomy was performed uneventfully. After the operation, the patient was extubated and transferred to the recovery room for postoperative care. Case 2. A 65-year-old woman was scheduled for basal segmentectomy (S7-10) of the right lung for lung cancer. She previously had a left lower lobectomy for lung cancer. After lobectomy, respiratory function data showed FVC was 2.47 L (103.4%) and FEV1.0 was 1.4 L (69.9%). Breathing room air, blood gas analysis showed pH 7.415; PaO2, 86.6 mmHg; PaCO2, 42.9 mmHg; SaO2, 96.9%; and base excess, 2.6 mEq/L. After placement of an epidural catheter at T5-6, anesthesia was induced with 3 mg/kg of thiopental followed by 0.15 mg/kg of vecuronium. Similar to case 1, a bronchial blocker detached from a Univent tube initially was introduced to the trachea, after which the patient was intubated with a standard 8.0-mm internal diameter tube and received a radial artery catheter. One-lung ventilation initially was tried, but oxygen saturation as measured by pulse oximetry (SpO2) rapidly decreased to 82%. One-lung ventilation was abandoned, and both lungs were ventilated until SpO2 returned to 100%; then, guided by fiberoptic bronchoscopy, the blocker was advanced into the bronchus intermedius and blocked the middle and lower lobes. Using this technique, SpO2 subsequently was maintained at 100% throughout the operation. Case 3. A 64-year-old man was scheduled for segmentectomy (S1) of the right lung to remove a tumor. He previously had a left upper lobectomy for lung cancer. After lobectomy, respiratory function data showed FVC was 2.82 L (87.3%) and FEV1.0 was 2.00 L (70.9%). Breathing room air, blood gas analysis showed pH 7.375; PaO2, 70.6 mmHg; PaCO2, 45.5 mmHg; SaO2, 93.0%; and base excess, 0.9 mEq/L. After placement of an epidural catheter at T7-8, anesthesia was induced with 1.5 mg/kg of propofol and 2 g/kg of fentanyl followed by 0.15 mg/kg of vecuronium. The trachea was intubated with an 8.0-mm internal diameter Univent tube. Anesthesia was maintained with propofol, 5 to 10 mg/kg/h, with intermittently administered 1.5% lidocaine epidural anesthesia. A radial artery catheter also was placed. Guided by fiberoptic bronchoscopy, a bronchial blocker was introduced into the right upper bronchus and blocked only the right upper lobe. Subsequently, normocapnia was maintained with sufficient oxygenation (SpO2, 100%) throughout the operation. *S. Hagihira, N. Maki, and M. Kawaguchi
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