Proprioception, the sense of position and movement of body segments, may not be known as much as other senses such as vision or audition. However, since the pioneer work of Sherrington, the critical role of proprioception in motor control has been increasingly highlighted. In particular, studies of human subjects massively deprived of proprioception after a viral infection, have largely demonstrated their inability to coordinate their actions. As this typically results in an inability to stand and walk, we focus here on the ability of deafferented patients to control their upper-limb movements. We will first present studies that provided striking evidence for the role of proprioception in movement coordination before presenting our recent work on the role of proprioception in motor learning and how the loss of large somatosensory fibres may affect visual perception. http://dx. After amputation, the cortical regions of which the neuronal activity was related to the control of the missing limb will gradually be active in relation to another, generally adjacent, part of the body. This reorganization often goes together with a vivid perception of the presence of the missing limb, called "phantom limb". A little known phenomenon, but experienced by many amputees, is that the phantom limb can be moved at will. The patients feel the movements to be made in correspondence with their will and they are able to copy with their intact limb the movement they "performed" with their phantom limb. Results of recent studies suggest that, despite the cortical reorganisation, M1 still can send motor commands to the missing limb. These motor commands, being unable to project on the missing limb muscles, project on the preserved muscles of the stump, resulting in specific muscle activation patterns. We will (1) show the large panel of phantom movements experienced by patients and (2) make a comparison between the EMG patterns evoked by phantom movements and those generated by the patients for the control of myoelectric prostheses. Funding: Project financed by the Region Provence-Alpes-Cote d'Azur (Projet ExplorAmp, 2012) and CNRS (DEFISENS, 2013).