In today's evolving healthcare landscape, leaders must innovate and collaborate to ensure safe, accessible, and high-quality care. Addressing complex issues like climate change, workforce resiliency crises, and the erosion of public trust, alongside equity and inclusive services, is critical. This article offers insights into the role of quality standards and assessment programs as catalysts for innovation and future collective impact. Using examples from Health Standards Organization and Accreditation Canada, it illustrates how these levers of change enable leaders to improve patient and workforce safety, advance integrated care, and strengthen the health of communities. Embracing people-centred and evidence-informed solutions to enable new mindsets and ways of working lays the foundation for sustainable, resilient learning health systems.