leriche and policard maximow and bloom ham 1. Matrix Development without influence by cells First development without influence of cells, later under influence of osteoblasts Derived as product of specific cells 2. Histogenesis of osteoblasts From C.T. cells, by differentiation, under influence of matrix From mesenchymal cells simultaneously with matrix formation Arising from specialization of less differentiated cells 3. Function of osteoblasts Restriction of growth of matrix Formation of interstitial substance Formation of matrix 4. Histogenesis of osteoclasts Fusion of osteoblasts; fibroblasts, reticulo-endothelial cells From mesenchymal cells Osteogenic cells 5. Function of osteoclasts Ca. and matrix resorption Dissolution of bone Form CO 2 which dissolves bone matrix phagocytic
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