Role Of Herbal Medicines Research Articles

Role of Herbal Medicines in Prevention and Management of Chronic Diseases

Role of Herbal Medicines in Prevention and Management of Chronic Diseases

The Role of Herbal Medicine in Modulating Bone Homeostasis.

Osteoporosis and other bone diseases are a major public health concern worldwide. Current pharmaceutical treatments for bone disorders have limitations, driving interest in complementary herbal medicines that can help maintain bone health. This review summarizes the scientific evidence for medicinal herbs that modulate bone cell activity and improve bone mass, quality and strength. Herbs with osteogenic, anti-osteoporotic, and anti-osteoclastic effects are discussed, including compounds and mechanisms of action. Additionally, this review examines the challenges and future directions for translational research on herbal medicines for osteoporosis and bone health. While preliminary research indicates beneficial bone bioactivities for various herbs, rigorous clinical trials are still needed to verify therapeutic efficacy and safety. Further studies should also elucidate synergistic combinations, bioavailability of active phytochemicals, and precision approaches to match optimal herbs with specific etiologies of bone disease. Advancing evidence- based herbal medicines may provide novel alternatives for promoting bone homeostasis and treating skeletal disorders.

A review on role of herbal medicine in daily life

Writing a review on the use of medicinal shops involves assessing their effectiveness and safety in treating colorful health conditions. To exhaustively assess their remedial value, it's pivotal to consider scientific substantiation, traditional knowledge, and implicit side effects. This review aims to epitomize and dissect the scientific exploration on the medical benefits of shops. These shops are constantly employed as food complements, seasonings, traditional drink constituents, and colorful skin related operations. By examining the being literature, this review provides an overview of the implicit remedial parcels associated with these shops. The shops presented in the exploration are zinger, black cumin seed, Isabgol etc. The number of cases seeking alternate and herbal remedy is growing exponentially. Herbal drugs are the conflation of remedial gests of generations of rehearsing croakers of indigenous systems of drug for over hundreds of times. Herbal drugs are now in great demand in the developing world for primary health care not because they're affordable but also for better artistic adequacy, better comity with the mortal body and minimum side goods.

The Role of Herbal Medicine in Traditional Healing

The Role of Herbal Medicine in Traditional Healing

Role of Herbal Medicine in Cardiovascular Activities

Herbal medicine has gained substantial attention for its potential role in supporting cardiovascular health. This chapter explores the intricate interplay between herbal compounds and cardiovascular activities, shedding light on their mechanisms of action and therapeutic applications. With a historical backdrop of traditional herbal medicine, the prevalence of cardiovascular diseases serves as a compelling backdrop for the investigation. The chapter delves into the multifaceted mechanisms by which herbal compounds influence the cardiovascular system. Notably, herbs exhibit vasodilatory effects, contributing to blood pressure regulation, and harbor potent antioxidant and anti-inflammatory properties that collectively mitigate oxidative stress and inflammation within the cardiovascular milieu. Furthermore, certain herbs intricately modulate lipid metabolism, holding promise in the management of dyslipidemia. A thorough analysis of well-known herbal treatments clarifies each one's unique contributions to cardiovascular health. Hawthorn is revealed to be the champion of heart health, and garlic demonstrates its mastery of cholesterol reduction. Ginkgo Biloba is notable for its capacity to improve circulation, and turmeric demonstrates powerful anti-inflammatory properties. The chapter also looks at herbal medicine's potential as an intervention for regulating fluid balance, arrhythmias, and hypertension. Examined is the potential for resveratrol-rich plants and green tea to protect against heart disease. Along with considerations for safety, interactions, and future study, the symbiotic relationship between stress reduction, adaptogenic herbs, and heart health is also discussed in this article. This chapter concludes with a thorough examination of the crucial part herbal medicine plays in cardiovascular health. The complex interaction between herbal substances and circulatory functions, from mechanisms of action to clinical applications, shows promise for a more integrative and holistic approach to cardiovascular care

The Role of Herbal Medicine as An Alternative Treatment Option for Endometriosis: A Literature Review

Introduction: Endometriosis is a benign gynecological disorder characterized by ectopic growth of endometrial tissue. This condition may deteriorate patient’s quality of life due to pain as its main manifestation and its complications, including impaired fertility and risk of ovarian cancer. Current standard endometriosis treatment still yields numerous side effects and controversy. Thus, herbal medicine is hoped to be the safer alternative treatment with excellent efficacy for endometriosis. Methods: The search of literature published in English or Bahasa Indonesia was performed by incorporating the search queries “endometriosis”, “herbal therapy”, “silymarin”, “curcumin”, “Viburnum opulus”, “Pueraria”, “Allium sativum”, “black garlic”, “naringenin” on databases including PubMed, Cochrane, Springer, Science Direct, Nature, and Google Scholar. The studies included were in vitro studies, in vivo studies, and clinical trials. Results: Various herbal treatments have been widely studied regarding their anti-inflammatory, antioxidant, neuroprotective, hepatoprotective, cardioprotective, antiallergy, and immunomodulatory capacity. A lot of herbal compounds have the potential to suppress and manage endometriosis through various mechanisms, such as inhibiting the migration and adhesion of endometriosis to other tissues, suppressing inflammatory response in endometriosis pathogenesis, generating antioxidant, inhibiting estrogen activity, and inducing apoptosis of endometriosis cell through a number of signaling pathways. Conclusion: Herbal medicine has the potential to manage endometriosis through various mechanisms. Further research is needed regarding the efficacy of herbal therapy in managing endometriosis.

Pharmacists' perspectives on recommending herbal medicines for acute infections: a qualitative study.

Community pharmacists have an essential role in antimicrobial stewardship by providing self-care advice for self-limiting infections. To explore community pharmacists' perceptions and experiences of advising patients on management of acute respiratory tract infections (RTIs) and urinary tract infections (UTIs), and to explore issues regarding use of over-the-counter (OTC) medicines, including herbal medicines. A qualitative study using semi-structured interviews with community pharmacists in England. Qualitative interviews with community pharmacists were carried out face to face and by telephone between November 2019 and March 2020. Data were collected through in-depth, semi-structured interviews, recorded and transcribed. A reflexive thematic analysis was undertaken. In total, 18 community pharmacists were interviewed. Three main themes were identified. Theme 1 was self-management recommendations. Community pharmacists considered patients' preferences when recommending self-management strategies. Some believed that conventional OTC medications had quicker and stronger effects, while others preferred herbal OTCs as a more natural approach, particularly for less severe symptoms. Theme 2 was factors influencing pharmacists' recommendations for acute infections. This included pharmacists' perceptions of patient preferences, nature or severity of illness, research evidence, training, commercial pressures, and patient concerns about medication cost. Theme 3 was pharmacist-patient communication. Pharmacists sometimes experienced challenges with language barriers and patients' expectations of receiving antibiotics. Pharmacists emphasised the importance of being trusted by their patients. There was widespread acceptance of their role in self-management advice for acute illness and interest in the role of herbal medicines, but pharmacists did not feel confident in recommending these. Pharmacists are central to the management of self-limiting infections. There is a need to educate the public about appropriate use of antibiotics and provide training and support for pharmacists on self-management strategies including herbal medicine.

The Role of Herbal Medicine in Oxidative Stress: Prevention of Diabetes

The pathophysiology of diabetes mellitus is heavily influenced by oxidative stress, which is defined by an imbalance between reactive oxygen species (ROS) and antioxidant defenses. Innovative methods for managing and preventing diabetes are required given that it is a growing worldwide health concern. Herbal medicine, which has a long history of use in traditional therapeutic methods, has drawn interest for its ability to reduce the incidence of diabetes and combat oxidative stress. The processes underpinning the damage caused by ROS to cellular components and signaling pathways are revealed in this chapter as it delves into the complex interactions between oxidative stress and diabetes. The essential function of antioxidant substances in reducing oxidative stress is investigated, emphasizing the change from traditional herbal knowledge to contemporary scientific validation. The botanical substances that provide a source of inorganic antioxidants are at the center of this discussion. Fenugreek (Trigonella foenum-graecum) and Bitter Melon (Momordica charantia), two important medicinal herbs, are investigated for their strong antioxidant capacities and their capacity to modify glucose homeostasis and insulin sensitivity.Scientific studies, including in vitro experiments and clinical trials, shed light on how well herbal treatments for diabetes prevention actually work. Additionally, the beneficial effects of herbal combinations are clarified, as well as the importance of combining these interventions with lifestyle changes. The fusion of herbal medicine and conventional therapies appears as a promising route for diabetes prevention as the movement toward holistic health gains popularity. In conclusion, this chapter underscores the multifaceted potential of herbal medicine in addressing oxidative stress as a crucial factor in diabetes prevention. By embracing the wisdom of ancient traditions and leveraging contemporary scientific insights, herbal interventions offer a holistic and integrative strategy to safeguard against the escalating global burden of diabetes.

An Insight View on the Role of Herbal Medicines in Infectious Diseases

Abstract:Nature always has enough spirit and resilience to transform our limited vision. Herbal medicines include products prepared from natural herbs which are employed to treat several diseases. In India, about 80% of drugs are of herbal origin. Nowadays, people are much more aware of the various side effects of synthetic drugs, which have molded their interest in herbal products and herbal remedies. In history, various infectious diseases or pandemic conditions have been treated or controlled with herbal medicines. Many herbal plants like Emblica officinalis (Euphorbiaceae), Withania somnifera (Solanaceae), Swertia chirata (Gentianaceae), Asparagus racemosus (Liliaceae), and Vinca rosea/Catharanthus roseus (Apocynaceae) have been reported to be of high medicinal values and preferred in the development of many newer drugs. The active component from plant extract is isolated, standardized, and undergoes safety trials for validation. Novel drug development from herbs is the amalgamation of practices of native systems of medicine and quite a lot of therapeutic experience of earlier generations. It is also believed that most herbal contents are safe, cheap, and easily available. Herbal drugs are useful in various diseased and pathogenic conditions like tuberculosis, cancer, diabetes, AIDS, jaundice, skin diseases, etc. Many countries with ancient cultures like India, Egypt, and America still use various herbal-based medications. Research for future herbal product development is increasing worldwide. Therefore, taking into consideration future perceptions of herbal remedies, this review deals with the present status and future exploration in the development of herbal drugs as modern beneficial agents for treating various infectious diseases and related pharmacological problems.

Network pharmacology-based prediction of efficacy and mechanism of Chongmyunggongjin-dan acting on Alzheimer’s disease

Objectives: Network pharmacology is a method of constructing and analyzing a drug-compound-target network to predict potential efficacy and mechanisms related to drug targets. In that large-scale analysis can be performed in a short time, it is considered a suitable tool to explore the function and role of herbal medicine. Thus, we investigated the potential functions and pathways of Chongmyunggongjin-dan (CMGJD) on Alzheimer’s disease (AD) via network pharmacology analysis.Methods: Using public databases and PubChem database, compounds of CMGJD and their target genes were collected. The putative target genes of CMGJD and known target genes of AD were compared and found the correlation. Then, the network was constructed using Cytoscape 3.9.1. and functional enrichment analysis was conducted based on the Gene Ontology (GO) Biological process and Kyoto Encyclopedia of Genes and Genomes (KEGG) Pathways to predict the mechanisms.Results: The result showed that total 104 compounds and 1157 related genes were gathered from CMGJD. The network consisted of 1157nodes and 10034 edges. 859 genes were interacted with AD gene set, suggesting that the effects of CMGJD are closely related to AD. Target genes of CMGJD are considerably associated with various pathways including ‘Positive regulation of chemokine production’, ‘Cellular response to toxic substance’, ‘Arachidonic acid metabolic process’, ‘PI3K-Akt signaling pathway’, ‘Metabolic pathways’, ‘IL-17 signaling pathway’ and ‘Neuroactive ligand-receptor interaction’.Conclusion: Through a network pharmacological method, CMGJD was predicted to have high relevance with AD by regulating inflammation. This study could be used as a basis for effects of CMGJD on AD.

Role of Herbal Medicine in Modern Medicinal Age: Importance of Coumarin, an Oxygen-containing Heterocyclic Compound of Benzopyrone Chemical Class

Role of Herbal Medicine in Modern Medicinal Age: Importance of Coumarin, an Oxygen-containing Heterocyclic Compound of Benzopyrone Chemical Class

Role of herbal medicines in the treatment of infectious diseases.

Herbal medicines have helped to cure illness because the practice has continued for generations. Multiple alkaloids/compounds that occur naturally (as against single extracts) exhibit synergistic actions such as antiviral, antibacterial, anti-protozoal, and antioxidant. The cases related to viral, protozoal, and bacterial infections were selected. Patients with amoebiasis, E-coli, gastrointestinal infection, skin and urinary tract infections were treated using herbal drugs. Diagnoses were confirmed with investigations. Due to their cost effectiveness, these medicines are in great demand for primary health care with cultural acceptability and minimal side effects. The aim of the reported study is to show the actual use of Indian medicinal plants used for the treatment of various types of infectious diseases. Cases varying from COVID 19 to gastrointestinal infection, viral diseases, skin and wound infections are being treated effectively with herbal drugs.

Herbal medicine in the treatment of COVID-19 based on the gut-lung axis.

http://links.lww.com/AHM/A33.

The Role of Herbal Medicine in the Treatment of Acne Vulgaris: A Systematic Review of Clinical Trials.

Over the past few decades, interest in medicinal plants and phytochemicals for the treatment of skin disorders, including acne vulgaris, has progressively increased. Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit, which mainly occurs in adolescents and young adults. The treatment focuses on the four main factors involved in its pathogenesis: increased sebum production, hyperkeratinization, overgrowth of Cutibacterium acnes, and inflammation. The treatment includes topical retinoids, benzoyl peroxide, antibiotics, and oral isotretinoin. In this regard, the use of herbal medicine as a complementary and alternative medicine is a promising strategy. The main objective of this study was to systematically evaluate the efficacy and safety of medicinal plants and phytochemicals in the treatment of acne vulgaris. Three scientific databases (PubMed, Web of Science, and Scopus) were searched from inception to January 2021. Clinical trials comparing herbal therapies with placebo or other medicines for the treatment of acne vulgaris were included and analyzed. Outcome measures of interest comprised acne lesions (inflammatory and noninflammatory), sebum production, acne severity, and quality of life. The risk of bias in the included randomized controlled trials (RCTs) was assessed using the Cochrane risk-of-bias tool. A total of 34 clinical trials involving 1753 participants met the inclusion criteria for this systematic review. Most trials showed that herbal medicine significantly reduces inflammatory and noninflammatory acne lesions and has a relevant effect on acne severity. Some medicinal plants revealed equal or higher efficacy to standard treatments. No significant difference between groups in sebum production and quality of life was observed and no severe adverse events were reported. This systematic review provides evidence that medicinal plants and phytochemicals are promising treatments for mild to moderate acne vulgaris. However, more quality of evidence and standardized methodologies are needed to support their effectiveness and safety claims.

An Overview of Herbal Medicines for Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung scarring condition with the histological characteristic of typical interstitial pneumonia. Injury to alveolar epithelial cells is a critical precursor in the pathogenesis of this disease. The prevalence of IPF is growing exponentially, with substantial morbidity and mortality rates increasing the burden on economic healthcare costs. A multidisciplinary approach for diagnosis is used to rule out the alternative causes of interstitial lung disease. Pirfenidone and nintedanib, two innovative antifibrotic medicines introduced in recent years, have provided therapeutic benefits to many IPF patients, and several IPF medications are in the early phases of clinical trials. However, available medications can cause unpleasant symptoms such as nausea and diarrhoea. More efforts have been made to uncover alternative treatments towards a more personalised patient-centred care and hence improve the outcomes in the IPF patients. Through a multi-level and multi-target treatment approach, herbal medicines, such as Traditional Chinese Medicine (TCM), have been identified as revolutionary medical treatment for IPF. Due to their natural properties, herbal medicines have shown to possess low adverse effects, stable therapeutic impact, and no obvious drug dependencies. Herbal medicines have also shown anti-inflammatory and anti-fibrotic effects, which make them a promising therapeutic target for IPF. A growing number of formulas, herbal components, and various forms of Chinese herbal medicine extracts are available for IPF patients in China. This review summarises the role of herbal medicines in the prevention and treatment of IPF.

The role of herbal medicines in treating cough in children

The physiological role of cough is to restore mucociliary clearance in the respiratory tract. However, if there are inflammatory changes against the background of a respiratory infection, cough may be non-productive and impair the patient’s quality of life. For a rational choice of drug, the true cause of cough should be determined on the basis of history, physical examination and, if necessary, additional instrumental/laboratory investigations. Modern phytopharmaceuticals are considered effective and safe for cough relief. Herbal medicines contain biologically active substances, which are incorporated into the metabolic processes of the body in a more natural way, in contrast to synthetic analogues. The article focuses on the effectiveness of an ivy leaf extract, which has a complex composition: it contains saponins, flavonoids, glycosides, as well as components of essential oils. Due to its composition, it has several effects: expectorant due to its secretolytic and mucolytic action, and antispasmodic based on the increased sensitivity of β2-adrenoreceptor cells of bronchial smooth muscle cells to endogenous and exogenous stimulation, on reducing intracellular calcium levels and bronchial relaxation. The efficacy of ivy leaf extract has been shown in a total of more than 20 clinical trials, mainly in children suffering from upper respiratory tract infections. Cough treatment aims at changing the rheological properties of the secretion and increasing the effectiveness of the cough. The good compatibility of herbal medicines with other drugs, including antibiotics, allows their use not only as monotherapeutic agents, but also in combination therapy for the treatment of cough in children.

SELECTED INDIAN MEDICINAL PLANTS FOR MITIGATING POLYCYSTIC OVARIAN SYNDROME: A REVIEW

The polycystic ovarian syndrome is one of the most frequent gynecological disorders among reproductive-age women (PCOS). The polycystic ovarian disease is also known as Stein Leventhal syndrome or high androgen anovulation syndrome. It is a common endocrine illness marked by polycystic ovaries, chronic anovulation, and hyperandrogenism, which causes irregular menstrual periods, hirsutism, acne, and infertility. It is linked with a high risk of hypertension, hyperlipidemia, and types 2 diabetes all of which can contribute to strokes and cardiovascular disease. It must be diagnosed early in order to avoid future health complications. Because it is a treatable condition, it can be treated with either natural or allopathic medicines. Treatment with phytoestrogenic and non-estrogenic herbs such as Bauhinia variegata, Asparagus racemosus, Saraca asoca, Caesalpinia bonducella, Nigella sativa, Vitex negundo, Cinnamomum zeylanicum, and Symplocos racemosa which are effective and safe, polyherbal formulation is obtained from medicinal plants. The role of herbal medicine in the treatment of PCOS is the topic of this review.

Role of herbal medicines in the treatment of Kidney stone: A brief review

Role of herbal medicines in the treatment of Kidney stone: A brief review

Role of herbal medicines in the treatment and management of corona disease

Role of herbal medicines in the treatment and management of corona disease

Synergistic effects of herbal medicines and anticancer drugs: A protocol for systematic review and meta-analysis.

Background:An increasing number of studies have been reporting combination therapy using herbal medicines and anticancer drugs, and the synergistic effects of this combination have gained much attention across the medical community. In this study, we will review and summarize all published studies that have investigated the synergistic interaction between herbal medicines and anticancer drugs.Methods:We will search the PubMed, Embase, and Cochrane Library databases. Studies investigated the synergistic interaction between herbal medicines and anticancer drugs will be included. The selection and extraction process will be performed by 2 independent reviewers, and we will perform qualitative synthesis.Discussion:The present study is being performed to investigate the herbal medicines and anticancer drugs that are used concomitantly, and to determine the combinations that are expected to show a synergistic effect. This knowledge will provide new insights into the possible role of herbal medicines in anticancer treatment.Review registration:Trial registration: OSF Registration number: DOI 10.17605/OSF.IO/H5QS9.