Role Of Airway Smooth Muscle Research Articles

Muscle Physiology and Protein Biochemistry

Although we now have a considerable understanding of the mechanics of bronchial smooth muscle and of the effects of numerous physiologic and pharmacologic agents on its behavior the exact role it plays in normal physiologic function is not clear.” This quotation from Otis1 admirably sums up what we know about the role of airway smooth muscle (ASM). In the absence of knowledge, theories abound. Controversies notwithstanding, there is no doubt that abnormalities of ASM contraction result in the severe bronchospasm of the early asthmatic response.