Large space truss structure is widely used in spacecrafts. The vibration of this kind of structure will cause some serious problems. For instance, it will disturb the work of the payloads which are supported on the truss, even worse, it will deactivate the spacecrafts. Therefore, it is highly in need of executing vibration control for large space truss structure. Large space intelligent truss system (LSITS) is not a normal truss structure but a complex truss system consisting of common rods and active rods, and there are at least one actuator and one sensor in each active rod. One of the key points in the vibration control for LSITS is the location assignment of actuators and sensors. The positions of actuators and sensors will directly determine the properties of the control system, such as stability, controllability, observability, etc. In this paper, placement optimization of actuators and sensors (POAS) and decentralized adaptive fuzzy control methods are presented to solve the vibration control problem. The electro-mechanical coupled equations of the active rod are established, and the optimization criterion which does not depend upon control methods is proposed. The optimal positions of actuators and sensors in LSITS are obtained by using genetic algorithm (GA). Furthermore, the decentralized adaptive fuzzy vibration controller is designed to control LSITS. The LSITS dynamic equations with considering those remaining modes are derived. The adaptive fuzzy control scheme is improved via sliding control method. One T-typed truss structure is taken as an example and a demonstration experiment is carried out. The experimental results show that the GA is reliable and valid for placement optimization of actuators and sensors, and the adaptive fuzzy controller can effectively suppress the vibration of LSITS without control spillovers and observation spillovers.