Currently, the unified strength criterion (USC), the three-dimensional Hoek-Brown (3D H-B) criterion and the generalized unified strength theory (GUST) are the three types of typical rock strength criteria. In this paper, a comparative study of the three types of strength criteria is performed for rocks. Based on the nonlinear characteristics of rock strength on meridian and deviatoric planes, the USC can predict rock strength under triaxial stress state. The USC is composed of two failure functions on meridian and deviatoric planes. The failure surface of the USC in principal stress space satisfies smoothness and convexity. The predicted strength for five types of rock under the true triaxial tests were compared among the USC, the GUST, and the 3D H-B criterion. The results indicate that the USC can effectively reflect the influence of the intermediate principal stress on rock strength and accurately predict rock strength under both triaxial tension (σ1=σ2>σ3) and triaxial compression (σ1>σ2=σ3). Additionally, the conventional triaxial tests were conducted on other eight types of rock to measure the strength on meridian plane. The predicted strengths for the eight types of rock on meridian plane were compared between the USC and the original H-B, which suggests that the USC is suitable for various types of rock and provides higher accuracy.