Structural and mechanical analyses of rock mass are key components for rock slope stability assessment. The complementary use of photogrammetric techniques and numerical models coupling discrete fracture networks with the discrete element method (DEM) provides a methodology that can be applied to assess the mechanical behaviour of realistic three-dimensional (3D) configurations for which fracture persistence cannot be assumed. A real case has been studied to show the complete methodology from the acquisition of the photogrammetric data to the numerical modelling of the potential progressive failure process occurring in the rock mass. Using a 3D mapping system and its associated structural mapping tool Sirovision, the topography and the discontinuity set of an unstable rock block located in a limestone layer of the Mount N,ron, located in the French Alps, were imported into a DEM code specially enhanced for the modelling of pre-fractured rock masses. A stability analysis has been carried out, emphasizing the contribution of rock bridge failure through a mixed shear-tensile failure process to the generation of new failure surfaces. This addresses limitations in methodologies using only shear strength reduction method. It is believed that the proposed methodology can strengthen the basis for a more comprehensive stability analysis of complex fractured rock slopes.