Exploration success relies heavily on the data obtained, but, significantly on the type of analytical methods deployed and the interpretation reached. A poorly analyzed data may obscure the true reflectivity of the data, and thus, compromised the decision made. A combined data processing approach of descriptive statistics, enrichment-depletion data normalization, geospatial elemental distribution, and stacked overlayed comparison of elements have been used in this study. The prime purpose was to demonstrate potential elemental anomalies, and predict areas of higher degree of confidence for subsequent exploration and mineral resource evaluation. One-hundred and sixty-six stream sediment samples from the Dodoma Region of the Tanzania Craton have been examined; to reveal potential elements or mineral commodity that warrant further exploration. Forty-three elements of target were examined, as this craton is globally known for its rich earth mineral commodity. Our result indicates an enrichment of transition metals (TMs) (Cu, Ni, Co, Cr, Mn and Zn), High Field Strength Elements (Y, Th, U, Zr, Nb, Hf, Ta and Pb), Large Ion Lithophile Elements (Ba and Rb) and Rare-Earth Elements (La and Ce), Platinum Group Element (Pd and Pt) and other metals (Au, As, Bi, W, Mo and Li).Obtained results point to a likely poly-metallic sources and processes; as the underlain geology is marked largely by pegmatite and migmatites, and moderate proportion of fine clastic sedimentary rocks, and minor volcanic rocks mostly to the northern domain. Theoretically, the Large Ion Lithophile Elements (LILEs), Rare-Earth Elements (REEs) and Platinum Group Elements (PGEs) are associated with felsic rocks or variable stages of plutonic granitization. Although, the TMs are often associated with mafic-ultramafic rocks, the linkage of such metals with organic-rich shales been reported elsewhere. These rocks may equally contribute to the occurrence of other metals as stated in this paper. Its intriguing to note a strong positive correlation of Li with TMs, possibility of Li control by mafic minerals in pegmatite bodies. This work proposes a polymetallic enrichment controlled by the area geology. To suggest an alluvial mining potential of the above elements in the area, resource evaluation is a requirement. The geospatial maps reveal areas worth focusing for subsequent exploration. The adopted geostatistical methods and other approach utilized in this research are effective, indicative of handling bulk exploration data for decision and subsequent exploration.
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