In this paper, H ∞ variable universe adaptive fuzzy control law is derived and applied to synchronize two FitzHugh—Nagumo neurons. Firstly, the different dynamical behavior of the nonlinear cable model based on the FitzHugh–Nagumo model responding to the various external electrical simulations (EES) is studied. Next, using the result of the analysis, a robust adaptive variable universe fuzzy control scheme is designed to synchronize two neurons. The computer simulations is provided for verify the efficiency of the designed synchronization scheme.