ABSTRACT There is growing evidence of socio-environmental injustice related to road noise pollution among marginalised populations. Patterns of inequality are not constant across space, and understanding the local and regional scales of environmental injustice is critical for appropriate policy and public health interventions. This study used road noise exposure data from the 2018 National Transportation Noise Map, socio-demographic variables from the U.S. Census Bureau, and advanced spatial modeling to examine the socio-environmental injustice of road noise pollution in Texas census tracts (N = 5265). Local spatial regressions predicted higher coefficients of noise pollution in census tracts with higher minority populations, higher poverty, and higher social deprivation. Strong associations were specifically identified in the rural southern and eastern border areas of Texas. Findings from this study may guide policymakers and public health agencies in identifying geographic locations where interventions can be pinpointed to target socio-spatial noise pollution disparities in Texas.