The Barauna region is situated on the West part of the Potiguar Basin, in the semi-arid domain of the RN State. Its geology comprehends mainly carbonate rocks (calcareous and dolomites) of the Jandaira Formation whose age is attributed to the Superior Cretaceous. This geological unit constitutes the karst Jandaira Aquifer, which is the main water supply source to human use and irrigation. The Jandaira Aquifer develops different levels of karst in the different sectors of the area, affecting the groundwater potentialities and its quality. In this article aspects in relation to the groundwater use and salinization are presented, highlighting the groundwater use to irrigation. It was developed using data obtained from geophysical studies, wells cadastre, topographic studies and the interpretation of the hydrochemistry data. In the Northern and Western sectors of Barauna the karsts are more expressive. In this case the water is Ca-HCO3 type water, with low salinity and in most of the cases it is good to human use and irrigation (classes C2S1T1 e C2S1T2 to irrigation); To the Southern part of Barauna, where the karsts are less expressive, the groundwater salinity is high, Ca-Mg-Cl type water and the quality suffers a certain restriction to human use and irrigation (Class C3S1T3).