Structural and tectonic features in the Pacific Coast of Mexico generate a high level of seismic activity in the Jalisco block (JB) region, making it one of the most attractive areas of the world for geophysical investigations. The Rivera–North America contact zone has been the object of different tectonic studies in recent years framed within the TsuJal project. To this day, this project is generating numerous crucial geophysical results, which significantly improve our understanding of the region. Our study is focused on the interaction between the south of the JB and Rivera plate (RP), which crosses the Middle America trench. We also cover an offshore–onshore transect of 130 km length between the eastern Rivera fracture zone and La Huerta region, in the Jalisco state. To characterize this region, we interpreted wide-angle seismic, multichannel seismic, and multibeam bathymetry data. The integration of these results, with the local and regional seismicity recorded by the Jalisco Seismic Accelerometric Telemetric Network and by the Mapping the Rivera Subduction Zone experiment, provides new insights into the geometry of the southern RP, which is dipping 12°–14° under the JB in the northeast–southwest direction. Moreover, our results provide new seismic images of the accretionary wedge, the shallow crust, the deep crust, and the upper-mantle structure along this profile.