The COVID-19 pandemic was a risky period for childhood obesity, due to the increase in unhealthy behaviors. Online interventions could prevent this problem. The aim of this study was to evaluate the feasibility and explore the effect of an online program on the BMI z-score of Mexican schoolchildren at 4 months during the pandemic. A pilot randomized controlled trial was conducted with 54 children. The intervention included three online sessions per week of nutrition and physical activity, as well as nutrition information for parents during 4 months. The control group received one nutrition digital brochure. Of the schoolchildren enrolled, 87% completed the study, and the intervention group attended 46% of the classes. At the end of the intervention, no significant difference between groups in the BMI z-score was observed (−0.02, 95% CI −0.19 to 0.15). However, the intervention group improved their quality of life and daily fruit consumption. This online intervention implemented during the COVID-19 pandemic was feasible, and the exploratory analysis showed positive trends in quality of life and daily fruit consumption but not in the BMI z-score and other secondary variables of Mexican schoolchildren. Additional strategies may be needed to improve attendance in online interventions and their impact on BMI in this age group.
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