Risk Factors For Premature Rupture Research Articles

Risk factors for premature rupture of membranes in pregnant women: a systematic review and meta-analysis

ObjectiveTo identify risk factors for premature rupture of membranes (PROM) in pregnant women.DesignSystematic review and meta-analysis.Data sourcesWeb of Science, PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure, Wanfang Database, Chinese...

Risk Factors for Premature Rupture of Membranes After Twenty-Eight Complete Weeks of Gestation

Risk Factors for Premature Rupture of Membranes After Twenty-Eight Complete Weeks of Gestation

Risk factors for premature rupture of membranes after twenty-eight complete weeks of gestation

Purpose: To identify the risk factors for premature rupture of membranes (PROM). Materiel and methods: This case-control study was carried out between 1st February and 31st July 2021. Files of women who delivered after having PROM or not were examined. The main variables recorded included maternal age and parity, familial, medical and obstetrical histories, the presence or not of nuchal cord at delivery, gestational age at delivery, birth weight and sex of newborn. Fisher exact test, t-test and logistic regression were used for comparison. P<0.05 was considered statistically significant. Results: Our frequency of PROM was 6.2% (94/1524 births). PROM occurred mostly at or after 37 weeks gestation (77.6%). Significant risk factors for PROM were 1st degree family history of PROM (aOR 31.36, 95%CI 2.57-382.11), fetal weight ≥4000g (aOR 14.78, 95%CI 2.72-80.20), cord round neck (aOR 6.36, 95%CI 1.17-34.66), past history of preterm delivery (aOR 3.42, 95%CI 1.02-11.52) and parity 4 or 5 (aOR 3.27, 95%CI 1.25-8.56). Conclusion: Women with these risk factors should be well followed up during pregnancy, especially during the third trimester, to allow prevention, if not, early diagnosis of PROM

AN OBSERVATIONAL STUDY ON THE RELATIONSHIP BETWEEN UROGENITAL INFECTIONS AND PREMATURE RUPTURE OF MEMBRANES.

Introduction: Urogenital infections are common causes of premature rupture of membranes (prom). The present study was aimed at correlating the colonization of the organisms and possible infections in the vagina and urinary tract of mothers presenting with premature rupture of membranes. 96 high vag Materials And Methods: inal swabs and urine of patients with premature rupture of membranes were subjected to bacteriological studies according to the recommended procedures. Out of 56 and 40 cases of PROM and PPROM, 25% and 32.5% had vaginal infect Results: ion respectively (Table 1) & 16.1%and 27.5% showed urinary tract infection respectively (Table 2). The most common organism isolated from high vaginal swab culture was Candida followed by Enterococcus and E.Coli. The most common organism isolated from urine culture was E.Coli, followed by Enterococcus in both PROM and PPROM cases. Uroge Conclusion: nital infections constitute major risk factors for premature rupture of membrane

Diagnostic Value of Neutrophil/lymphocyte Ratio and Platelet/lymphocyte Ratio in Premature Rupture of Membranes Complicated by Sepsis.

To investigate the predictive value of neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) in premature rupture of membranes complicated by sepsis. A descriptive study. Department of Paediatrics, Affiliated Hospital of Yanbian University, China, from January 2020 to June 2021. Ninety-nine children with premature rupture of membranes and sepsis were included as group A and 99 children without sepsis were included as group B. Logistic regression analysis was used to analyse the risk factors for premature rupture of membranes complicated by sepsis. The diagnostic value of PLR and NLR in sepsis complicated by premature rupture of membranes was assessed by subject operating characteristic curve (ROC) curves. Univariate analysis showed significant differences between groups A and B in terms of mode of delivery, lymphocyte count, platelets, PLR and NLR (p <0.05). Logistic regression analysis showed that mode of delivery, platelets, PLR and NLR were independent risk factors for premature rupture of membranes complicated by sepsis (p <0.05). The ROC area for PLR was 0.781 (95% CI: 0.718-0.844, p <0.001), which was greater than that for NLR when premature rupture of membranes complicated by sepsis was predicted. When the PLR was >93.072, the sensitivity of predicting premature rupture of membranes complicated by sepsis was 67.7% and the specificity was 79.8%. PLR and NLR have a high predictive value for premature rupture of membranes complicated by sepsis. Among them, the predictive value of PLR was greater than NLR. Premature rupture of membranes, Sepsis, PLR, NLR, Subject operating characteristic curve (ROC).

Analisis Faktor Resiko Ketuban Pecah Dini Di Rsud Mukomuko Kabupaten Mukomuko Tahun 2021

Premature rupture of membranes is very dangerous for pregnant women and their babies, the danger of premature rupture of membranes is infection occurs in mother and baby. The rupture of the membranes leaves the baby unprotected by the amniotic membrane and exposed to contact with the outside world, which causes bacteria to enter the mother's womb and infect both mother and baby. This can be life-threatening for both mother and baby. In addition, the birth of a baby that is less than the normal time causes premature babies and the risk of fetal defects is high. The purpose of this study was to analyze the risk factors for premature rupture of membranes in Mukomuko Hospital, Mukomuko Regency. The method used is descriptive-analytical research design using a case-control design. The population in this study were all mothers who gave birth at the Mukomuko Hospital, the sample in this study amounted to 100 people with a ratio of case and control groups of 1:1. Case samples (cases) were taken by total sampling, namely (50 mothers who gave birth with PROM), while the control sample was taken by random sampling from the entire population who did not experience premature rupture of membranes. Bivariate statistical test using Chi-square (X²). The results of univariate analysis most of the respondents (74.0%) were not infected, most of the respondents (71.0%) did not do pregnancy exercise, most of the respondents (54.0%) were primiparous, most of the respondents (82.0%) had no history of premature rupture of membranes, some respondents (50.0%) experienced premature rupture of membranes and some respondents (50.0%) did not experience premature rupture of membranes. The results of the bivariate analysis showed that there was a relationship between infection, pregnancy exercise, parity, and a history of PROM with the incidence of premature rupture of membranes. It is hoped that the hospital must have socialization of pregnancy exercise and the dangers of KPD in pregnant women.

Amniocentesis in twin gestation: the association between gestational age at procedure and complications.

Third trimester amniocentesis is often performed when indications arise after 24weeks of gestation-typically to investigate new sonographic findings, and might be related to pre-term birth. Scarcity of data exists concerning the risks of third-trimester amniocentesis in twin pregnancies. A retrospective cohort study of all twin gestations that underwent amniocentesis in a tertiary hospital between 2007 and 2016. Outcomes and procedure-related complications were compared between third-trimester (≥ 24weeks) and mid-trimester amniocentesis (16-23weeks). Primary outcome was defined as membrane rupture within four weeks of procedure. Logistic regression analysis was utilized to adjust results to potential confounders. Overall, 185 eligible women were included, of them, 28 (15.1%) underwent third-trimester amniocentesis and 157 (84.9%) underwent mid-trimester amniocentesis. Women in the third-trimester amniocentesis group were younger and presented higher frequencies of intra-uterine growth restriction (31.5 vs. 35.3, p < 0.001, and 28% vs. 10% p = 0.015, respectively). The prevalence of membrane rupture within 4weeks of the procedure was significantly higher in the third-trimester amniocentesis group (31% vs. 1%, p < 0.001). Delivery rates after third-trimester amniocentesis within 1, 2 and 4weeks of the procedure were 11%, 14.8% and 52%, respectively, versus 0% following mid-trimester amniocentesis (p < 0.001). Gestational age at delivery was similar between the groups (35.7 vs. 36.4 gestational weeks, p = 0.34). In multivariate analysis, gestational age at amniocentesis was found to be an independent risk factor for premature rupture of membranes within 4weeks of the procedure. Third trimester amniocentesis in twin pregnancies is associated with significantly higher rates of procedure-related membrane rupture compared to mid-trimester amniocentesis.

Pathogen profile and risk factors of aerobic vaginitis in pregnant women: a retrospective cohort study.

Vaginitis is one of the most common gynecological diseases in women and may severely affect the quality of life in patients. However, very few studies have investigated aerobic vaginitis (AV) in pregnant women, and our study was designed to identify the pathogen profile, clinical importance, and risk factors of AV in pregnancy. This was a retrospective cohort study enrolling 685 women who attended our hospital between July 2018 and June 2020. Based on the incidence of AV, enrolled women were divided into an AV group and healthy control group, and demographic and clinical characteristics were retrospectively collected by two independent investigators. Some pathogens of AV were tested using quantitative real-time polymerase chain reaction for higher accuracy. Pregnancy outcomes were also retrospectively collected. Univariable and multivariable logistic regression analysis was used to determine the risk factors of AV incidence and adverse pregnant outcomes. Enrolled women were divided into an AV group of 182 women and healthy control group of 503 women. The proportions of women with a history of cesarean delivery and history of vaginal infection differed between the groups (P=0.002 and <0.001, respectively). The mean gestational week at diagnosis of AV was 22.3±8.6 weeks, and the most common pathogen of AV was Escherichia coli (28.6%). After adjustment using multivariable logistic regression, a history of vaginal infection acted as an important risk factor of AV incidence, while a history of cesarean delivery, college education or above, and being employed could protect pregnant women from AV. In addition, the incidences of preterm birth, premature rupture of membranes, neonatal jaundice, and neonatal infection were much higher in the AV group than in the control group, showing significant difference (P<0.001, <0.001, =0.007, and =0.025). After adjustment using multivariable logistic regression, the incidence of AV and older age were important risk factors of premature rupture of membranes and neonatal infection. Compared with healthy pregnant women, the presence of AV may increase the incidence of adverse outcomes. More attention should be paid to pregnant women with a history of vaginal infection.

Anaerobic dysbiosis of the cervical canal as a risk factor for premature rupture of membranes

BACKGROUND: To identify the most significant predictors of premature rupture of membranes in full-term pregnancy with the use of RT-PCR analysis of cervical canal smear.&#x0D; &#x0D; MATERIALS AND METHODS: On the basis of City Clinical Hospital No. 1 named after N.I. Pirogov (Samara), a cervical smear was examined by RT-PCR using a standard panel Femoflor-16. The study involved 47 pregnant women at 37-41 weeks of gestation: the control group consists of 19 pregnant women without premature rupture of the membranes (PROM), and 28 pregnant women with PROM, were included in the main group. The most significant risk factors of PROM were revealed with the use of the Classification Trees.&#x0D; RESULTS: The following risk factors of PROM were identified: the number of Lactobacillus spp. less than 99.3% (sensitivity 75%, specificity 68%); total anaerobic microflora above 0.55% (sensitivity 71%, specificity 68%), Gardnerella vaginalis / Prevotella bivia / Porphyromonas spp. more than 0.08% (sensitivity 64.3%, specificity 73.7%) and Megasphaera spp. / Veilonella spp. / Dialister spp. more than 0.06% (sensitivity 66.7%, specificity 52.6%). If at least one of the above criteria was identified, the patient was attributed to the high risk group for PROM; when all four indicators of the distribution of microorganisms are taken into account, the sensitivity of the method was 85.5%, specificity was 68.4%, the predictive value of positive and negative diagnostic results (models accuracy) were 78.7%.&#x0D; CONCLUSIONS: The most prognostically significant risk factors for the development of PROM in the study of the cervical microbiota are the number of Lactobacillus spp. less than 99.3%; Gardnerella vaginalis / Prevotella bivia / Porphyromonas spp. more than 0.08%; Megasphaera spp. / Veilonella spp. / Dialister spp. more than 0.06%.

Risk Factors for Premature Rupture of the Membranes

The incidence of premature rupture of membranes (PRM) ranges from 8-10% at term pregnancy and 1% in preterm pregnancy. The incidence of PRM at RSUD dr. SoegiriLamongan in 2017 amounted to 16,43%. The purpose of this study was to analyze risk factors of the occurrence of premature rupture membranes in RSUD Dr. SoegiriLamongan. The research used descriptive analytical method with cross sectional approach. The sample is 268 maternity mothers, divided into 134 mothers giving birth with PRM and 134 normal maternity mothers at Dr. Soegiri Lamongan on 2018. Sampling is done by simple random sampling. Data collection uses patient medical record and with multivariate multiple logistic regression analysis.The results showed that presentation abnormalities with a p value of 0.045 &lt;0.05 and CPD with a p value of 0.002 &lt;0.05. Based on the Odds Ratio (OR) values ​​as follows: Maternal age OR 1,141, OR parity 0.933, OR fetal presentation 2,779, OR Twins 1,394, OR CPD 6. and OR Large infants 0.783.Meaning that there was a significant influence between fetal presentation and CPD on PRM.

Risk Factors of Premature Rupture of Membrane in A Tertiary Care Hospital, Bangladesh

Background : Premature Rupture of Membrane (PROM) is one of the most common complication of pregnancy. A woman with premature rupture of membrane is at risk of perinatal morbidity and mortality and also associated with maternal morbidity and psychological stress. Objective of this study was to determine incidence and risk factors of pregnant woman with PROM admitted in a tertiary hospital at Chattogram, Bangladesh.&#x0D; Materials and methods : This prospective observational study conducted in the Department of Obstetrics and Gynaecology at Chattogram Maa-O-Shishu Hospital Medical College (CMOSHMC) Chattogram from 1stJanuary 2018 to 31st December 2018. In this period total admitted antenatal patients were 8117. Among the pregnant patients with PROM were 665 and their weeks of gestation were &gt; 28 weeks. Data was collected by interviewer with semi structured questionnaire &amp; check list.&#x0D; Results : Incidence of PROM was 8.2%. PROM was found to be frequent (53%) in younger age group between 20-24 years. It was also commonly in primigravida (61.8%). Term PROM was higher (69.2%) than pre-term PROM (30.8%). 93.3% were singleton pregnancies, 6.4% were twins and .3% were triplets. Analysis of risk factors revealed ectiology was unknown in 46 (6.8%) low socioeconomic condition (60.6%), anaemia (45 %), lower genital tract infection (35.6%) UTI (31%) previous history of PROM (27.9%) malpresentation (15%) multiple pregnancy (6.7%) polyhydramnios (6%) history of recent coitus (12%) DM and GDM (10.5%) were commonly associated with PROM.&#x0D; Conclusions : Early identification of various risk factors causing PROM and their management can prevent premature deliveries and its complications to some extent as well as serious maternal complication like Chorioamnionitis.&#x0D; Chatt Maa Shi Hosp Med Coll J; Vol.19 (2); July 2020; Page 5-8

Maternal and Neonatal Outcomes and the Associated Risk Factors for Premature Rupture of Membranes

ABSTRACT Premature rupture of membrane (PROM) has significant adverse events in the prenatal, peripartum, and neonatal period. Understanding the maternal and neonatal outcomes of PROM is very important to reduce maternal and child mortality by prevention of complications and better management of the condition. The present study is undertaken to determine the maternal and fetal outcomes in patients with PROM and factors influencing the maternal and neonatal outcomes following PROM. We retrospectively evaluated the maternal and neonatal outcomes and the associated risk factors for 200 consecutive singleton pregnancy outcomes by PROM. Our results suggest that the mean age of the study participants was 22.90 ± 3.45 years ranging from 18–40 years. The estimated occurrences of unfavorable maternal and neonatal outcomes were 24.5 and 28.0%, respectively. Fever (67.3%) followed by puerperal sepsis (12.3%), wound infection (6.1%), and postpartum hemorrhage (6.1%) were common maternal outcomes and birth asphyxia (55.4%) followed by neonatal septicemia (25.0%) and convulsion (5.4%) were common neonatal outcomes. C-reactive protein (CRP) was positive among 44.0% of the mothers, and Escherichia coli was the commonest organism isolated in the cervical swab. The positive serum maternal CRP levels with an adjusted odds ratio (AOR) of 3.3 and 4.8 and latency in conducting delivery with an AOR of 1.1 each were the significant independent predictors of the maternal and neonatal morbidities (p &lt; 0.05). How to cite this article: Chandra SN, Pradeep MR, Shashikumara. Maternal and Neonatal Outcomes and the Associated Risk Factors for Premature Rupture of Membranes. J South Asian Feder Obst Gynae 2020;12(6):402–407.

Risk factors of premature rupture of membranes in public hospitals at Mekele city, Tigray, a case control study

BackgroundThe incidence of premature rupture of membranes ranges from about 5% to 10% of all deliveries. A woman with premature rupture of membranes is at risk of intra-amniotic infection, postpartum infection, endometritis, and death. A neonate born from premature rupture of membranes mother is at high risk of respiratory distress syndrome, sepsis, intraventricular hemorrhage and death. Little is known regarding the risk factors in Ethiopia. Therefore, this study was conducted to identify risk factors of premature rupture of membranes among pregnant women admitted to public hospitals in Mekelle city, Tigray, Ethiopia.MethodsHospital based unmatched case control study design was implemented on 240 samples (160 controls and 80 cases) from pregnant mothers admitted to public hospitals in Mekelle city from February – April/2016. Data was collected by interviewer administered Structured questionnaire and checklist. Binary logistic regression model was used to see the association between dependent and independent variables and multivariable logistic regression was used to identify the independent predictors of premature rupture of membranes.ResultsA total of 160 controls and 80 cases were enrolled in the study. Multivariable logistic regression showed that history of abortion [AOR 3.06 (CI: 1.39, 6.71)], history of PROM [AOR 4.45 (CI: 1.87, 10.6)], history of caesarean section [AOR 3.15(CI: 1.05, 9.46)] and abnormal vaginal discharge in the index pregnancy [AOR 3.31(CI: 1.67, 6.56)] were positively associated with premature rupture of membranes.ConclusionsPast obstetric history and risks in the index pregnancy have an association with premature rupture of membranes. The finding of the study suggests early identification and treatment of genitourinary infection.

Factores de riesgos de ruptura prematura de membranas. Hospital Provincial General Docente Riobamba. noviembre 2017-febrero 2018

Se realizó un estudio observacional, de tipo descriptivo y corte transversal con enfoque mixto; cuyo objetivo de determinar los factores de riesgo de ruptura prematura de membranas en las pacientes ingresadas con ese diagnóstico en el Hospital Provincial General Docente Riobamba durante el período noviembre 2017-febrero 2018. Se trabajó con la totalidad de la población, la que estuvo integrada por 17 embarazadas en el contexto de investigación. Se aplicó una guía de entrevista estructurada la misma que fue sometida a valoración por especialistas integrado por siete docentes vinculadas a las tutorías de prácticas preprofesionales en el área del Proceso de Atención de Enfermería en Salud Sexual y Reproductiva de la Universidad Nacional de Chimborazo; el 85,71 % de las consultadas consideraron el instrumento como muy adecuado. El 52,94 % de las mujeres estudiadas fue mayor de 26 años, tenía estado civil casadas y nivel de instrucción de secundaria. El factor clínico más relevante fue infecciones de vías urinarias y cérvico-vaginales durante el embarazo; sin embargo, entre los obstétricos fueron los controles obstétricos escasos y el oligoamnios. Los datos arrojaron la ausencia de aquellos relativos a ser víctima violencia familiar, consumo de sustancias tóxicas, auto medicación, relaciones sexuales durante los últimos 15 días del embarazo, tacto vaginal y/o amniocentesis en las horas previas a la presentación de la entidad en cuestión, embarazo múltiple, antecedentes personales de RPM, incompetencia del cérvix y polihidramnios.

Role of Apoptosis Inducing Factor (AIF) as Risk Factors of Premature Rupture of Membranes

Premature rupture of membrane (PROM) is an obstetric problem related to the prevalence, prematurity, morbidity and mortality of perinatal. The etiology of PROM is multifactorial and the mechanism remains unclear. The weakening of amniotic membrane is suspected due to various biochemistry process that causing remodeling and apoptosis, and the stretch of the amniotic membrane. Apoptosis plays an integrated role in the pathogenesis of PROM. The mechanism of apoptosis is through caspase-dependent and caspase-independent pathway. Apoptosis protein such as Apoptosis Inducing Factor (AIF) as caspase independent are hypothesized to be involved as the risk factor of PROM. To determine the role of AIF as caspase independent in the mechanism of patogenesis of premature rupture of membranes. A case-control study with PROM as a case, and non-PROM as a control at 20-42 weeks gestation age. Amniotic tissue was taken after delivery of the placenta. Immunohistochemical examination of AIF was done at Integrated Lab. Biomedic Medical Faculty of Udayana University in Bali. The study was conducted on 37 cases of PROM and 46 cases non PROM. There was no characteristic difference between the case and control groups (p&gt;0.05). The expression of positive AIF is a risk factor of PROM of 5.10 times (OR = 5.10; CI 95% = 1.86 to 13.96 ; p = 0.001). AIF expression was more in the group of PROM. AIF expression is a risk factor for premature rupture of membranes.

Role of Caspase-3 as Risk Factors of Premature Rupture of Membranes

Introduction Premature rupture of membranes (PROM) is one of the complications of pregnancy and health problems in the field of maternal and neonatal care in the world, including Indonesia, which is related to the prevalence, prematurity, morbidity, and mortality in the perinatal maternal

Risk Factors of Premature Rupture of Membrane

Maternal mortality rate in Indonesia based on 2012 Indonesia Demographic and Health Survey is 359 per 100,000 live births. Causes of the maternal mortality are still dominated by bleeding, preeclampsia/eclampsia and infections. One of causes of infections is premature rupture of membrane (PROM). PROMmay increase morbidity and mortality among mothers and children. Incidence of PROM is amount 10.7% of all childbirths. This study aimed to analyze risk factors of PROM incidence at Mother and Child Hospital of ANNISACiteureup, Bogor District in 2014. This study was analytical study using case control design. Samples consisted of case as many as 114 mothers who suffered from PROM and control as many as 228 mothers who did not suffer from PROM. Results of study showed that risk factors of PROM were age, parity, education. Based on multivariate analysis, education was the most dominant risk factor toward PROM incidence.AbstrakAngka kematian ibu di Indonesia berdasarkan Survei Demografi dan Kesehatan Indonesia (SDKI) tahun 2012 sebanyak 359 per 100.000 kelahiran hidup. Penyebab kematian ibu tersebut masih didominasi oleh pendarahan, pre-eklampsia/eklampsia, dan infeksi. Salah satu penyebab infeksi adalah ketuban pecah dini (KPD). KPD dapat meningkatkan morbiditas dan mortalitas pada ibu dan anak. Insiden kejadian KPD sekitar 10,7% dari seluruh persalinan. Penelitian ini bertujuan untuk mengetahui faktor risiko kejadian KPD di Rumah Sakit Ibu dan Anak (RSIA) ANNISA Citeureup, Kabupaten Bogor tahun 2014. Penelitianini merupakan penelitian analitik dengan rancangan penelitian kasus kontrol. Sampel terdiri dari 114 orang kasus ibu yang mengalami KPD dan kontrol sebanyak 228 ibu bersalin yang tidak mengalami KPD. Hasil penelitian menunjukkan faktor risiko terhadap kejadian KPD yaitu usia, paritas, pendidikan.Berdasarkan analisis multivariat, didapatkan faktor yang paling dominan berisiko terhadap kejadian KPD yaitu pendidikan.

Clinical study of high risk factors for poor prognosis in the neonatal respiratory distress syndrome

Objective To analyze high risk factors for poor prognosis in the refractory neonatal respiratory distress syndrome(NRDS). Methods A retrospective analysis was conducted at NICU in the Affiliated Hospital of Xuzhou Medical university.The newborns with NRDS, chest radiograph for grades 3 and 4, who required mechanical ventilation and pulmonary surfactant(PS) therapy were recruited from January 2014 to December 2015.According to treatment rusults, they were divided into death group(21 cases) and survival group(25 cases). Data regarding antenatal corticosteroid administration, maternal high risk factors, the basic situation of neonatal in the perinatal period, surfactant applications, the blood routine, albumin, lactate dehydrogenase(LDH), creatine kinase(CK), creatine kinase isoenzyme(CK-MB), blood coagulation function with the first 24 hours after birth were collected and analyzed. Results The frequency of using PS in the death group and the survival group was (2±0.9) times and (1.5±0.6) times, the difference between the two groups was statistically significant(t=2.131, P=0.039). Dangerous placenta previa in death group was 19%(4/21), in the survival group was 0%(0/25), the two groups had statistical differences(χ2=5.215, P=0.022). CK in death group was( 541.5±399.1) U/L, in the survival group was (345.4±173.3) U/L, the difference between of the two groups was statistically significant(t=2.224, P=0.031). Prothrombin time(PT) in the death group was (23.2±6.3) s, in the survival group was (18.5±3.6) s, there was a significant difference between the two groups(t=3.008, P=0.039). Maternal risk factors of premature rupture of the survival group(38.9%) was higher than that of death group(5.0%), the two groups was statistically significant(χ2=4.29, P=0.038). The application of prenatal hormone NRDS newborns were more likely to survive, there was statistical difference between two groups(χ2=5.197, P=0.023). Multivariate Logistic analysis showed that PT was an independent risk factor for poor prognosis of NRDS. Conclusion PT is an independent risk factor for poor prognosis of neonatal respiratory distress syndrome. Key words: Respiratory Distress Syndrome; Newborn; Prothrombin time; Pulmonary surfactant; Prognosis

Maternal Risk Factors of Premature Rupture of Membrane (PROM) after 37 Weeks of Pregnancy

Maternal Risk Factors of Premature Rupture of Membrane (PROM) after 37 Weeks of Pregnancy

Факторы риска преждевременного разрыва плодных оболочек у женщин с преждевременными родами в Кемеровской области

Факторы риска преждевременного разрыва плодных оболочек у женщин с преждевременными родами в Кемеровской области