Uniform bolt load is critical to achieve leak-free service in pressure vessel gasketed joints. In a previous work, the authors presented the tetraparametric assembly method, which enabled to obtain a uniform final load distribution in a one-pass tightening sequence. The accuracy of the method was proved by finite element analysis and experimental tests. However, the tetraparametric assembly method was only developed for one-pass tightening sequences, and in some cases more than one pass can be necessary. Furthermore, the method was only validated for a particular joint geometry. In this sense, the present work generalizes the method for two-pass tightening sequences and studies the range of application.