A flexible wing with a large aspect ratio emerges in many modern engineering applications (e.g. solar planes and super large wind turbine blades) and its interaction with incident flow differs markedly from conventional fluid–structure interactions (FSI), exhibiting frequently a large three-dimensional (3D) deformation. Yet, there is little information on how such deformation may change wing aerodynamics. This work investigates the aerodynamic performance of deformed and cantilever-supported NACA0012 rigid wings with an aspect ratio of 9, using ANSYS Fluent with the SST-κ-ω turbulence model at a chord-length-based Reynolds number Rec of 1.5 × 105. Numerical simulation is validated experimentally. The wing tip bending displacement is up to 4.14c, and the maximum twisted angle is up to 7°. The angle α of attack varies from 0° to 20° at mid span of the wing. It has been found that the torsional deformation can significantly advance the local flow separation, reattachment, bubble length, and transition from laminar to turbulence, resulting in a drop in the critical angle αcr of attack, at which the separation bubble size reaches the maximum. Accordingly, the lift and drag coefficients increase, as well as the bending and pitching-up moments, though the stall is advanced due to a change in local α. The tip vortex is also enhanced, inducing strong downwash postponing the separation bubble on the wing and resulting in redistributed force near the wing tip that increases markedly the local bending moment but decrease the local pitching-up moment. On the other hand, the bending deformation tends to produce an effect opposite to the torsion on the flow structure and causing little change in the lift coefficient, though reducing the induced drag and moments appreciably. With both deformations in place, the torsion overwhelms the bending in general in terms of its impact upon aerodynamics and flow structures, the latter acting to cancel at least partially the effect of the former.