Rib Malformations Research Articles

Multiple nevoid basal cell carcinoma syndrome. (Report of five cases in a family).

Five cases of MNBCCS caused by a dominant gene in three generations of one family are described. The history suggests that one other member of the family is affected. Another a 6 months old child, has some suggestive features—Skin lesions and/or dental cysts were major clinical signs which caused the three older patients to present for treatment. The disease was unsuspected in two younger patients 7 and 5 years old.— Intracranial calcifications and rib malformations were present in all the patients in whom the disease was proved, and all showed generalised bone changes.

Rib gap defects with micrognathia. The cerebro-costo-mandibular syndrome--a Pierre Robin-like syndrome with rib dysplasia.

Two patients with a syndrome of severe rib malformations and hypoplasia of the mandible are added to a total of 4 found in the literature.Rib defects should be looked for in cases of the Pierre Robin syndrome.

The teratogenic profile of sodium arsenate in the golden hamster.

The spectrum of developmental malformations resulting from the injection of dibasic sodium arsenate into pregnant golden hamsters varies with the time of injection during the critical stages of embryogenesis. However, the spectrum reveals a group of malformations, including anencephaly, renal agenesis, and rib malformations which are quite different from the spectrum of developmental anomalies induced by other teratogenic agents, including certain heavy metals.