Background: Amavata is a very challenging and burning problem in society. The clinical presentation of Amavata is closely related to the special variety of musculoskeletal disorder rheumatoid arthritis (RA). There is no medical system that is successful in providing a complete cure for the disease, so the Ayurvedic approach toward the treatment of Amavata is needed in the present era. The prevalence of RA is approximately 1% of the total population. For the management of RA in allopathic science, DMARDs & steroids are used frequently. Due to the lack of effective drugs and major problem in society, this disease for the study has been selected. Aim and Objectives: To study the efficacy of Erandbeejadi Gutika and Pippalyadi Gana Kashaya with modified Ruksha Sweda in the management of Amavata (RA). Methodology: It will be a single-center, randomized, open-clinical study. In this study, 60 clinically diagnosed patients of Amavata were selected and randomly divided into two groups by coin method. Erandbeejadi Gutika will be given in the dose of two tablets (each 500 mg) four times in a day with lukewarm water before meal for 90 days along with the modified Ruksha Pottali Sweda, while Pippalyadi Gana Kashaya will be given 50 ml two times in a day before the meal along with the modified Ruksha Pottali Sweda. Statistical analysis will be done using the Wilcoxon matched-pairs signed ranks test for the analysis of nonparametric data, while paired t-test will be used for parametric data analysis, and mann-whitney test and unpaired t-test will be used for intergroup comparison.