Distribution Of Rhesus Blood Groups Research Articles

ABO-Rh Blood Groups Distribution among King Khalid University Girls Students: A Prevalence Study

Objective: A questionnaire–based prevalence study was carried out on a random sample from various girls’ science college, KingKhalidUniversity, to find out the distribution pattern of ABO and Rh blood groups among Saudi females, which would not only help in blood transfusion services but also eliminate the risk of erythroblastosis fetalis in the neonates. Method: The procedure for this study was done by giving the questionnaire to 3287 female students. Each participant filled out the questionnaire and gave it back after answering all the questions. The participants were volunteered to fill out the questionnaire. Results: Of the 3287 female students enrolled in this study, 965 students know their blood groups. Amongst ABO system, blood group O was the most common (57.31%) followed by A (32.74%), B (9.22%), and AB (0.73%), respectively. Regarding rhesus system, Rhesus positive was more common (90.3%) than Rhesus negative (9.7%). Conclusion: The current study documents ABO and Rhesus blood group distribution pattern amongst King Khalid University Girls Students. Findings ensured that there is need for educational and community support program for effective management of medical emergencies.

Phenotypic and allelic distribution of the ABO and Rhesus (D) blood groups in the Cameroonian population

Data on blood group phenotypes are important for blood transfusion programs, for disease association and population genetics studies. This study aimed at reporting the phenotypic and allelic distribution of ABO and Rhesus (Rh) groups in various ethnolinguistic groups in the Cameroonians. We obtained ABO and Rhesus blood groups and self-identified ethnicity from 14,546 Cameroonian students. Ethnicity was classified in seven major ethnolinguistic groups: Afro-Asiatic, Nilo-Saharan, Niger-Kordofanian/West Atlantic, Niger-Kordofanian/Adamawa-Ubangui, Niger-Kordofanian/Benue-Congo/Bantu/Grassfield, Niger-Kordofanian/Benue-Congo/Bantu/Mbam and Niger-Kordofanian/Benue-Congo/Bantu/Equatorial. ABO allelic frequencies were determined using the Bernstein method. Differences in phenotypic distribution of blood groups were assessed using the chi-square test; a P value <0.05 being considered as statistically significant. The frequencies of the antigens of blood groups O, A, B and AB were 48.62%, 25.07%, 21.86% and 4.45%, respectively. Rhesus-positive was 96.32%. The allelic frequencies of O, A and B genes were 0.6978, 0.1605 and 0.1416, respectively. Phenotypic frequencies of the blood groups in the general study population and in the different ethnolinguistic groups were in agreement with Hardy-Weinberg equilibrium expectations (P > 0.05). The frequencies of O, A, and B blood phenotypes were significantly lower, respectively, in the Nilo-Saharan group (P = 0.009), the Niger-Kordofanian/Benue-Congo/Bantu groups (P = 0.021) and the Niger-Kordofanian/West-Atlantic group. AB blood group was most frequent in the Niger-Kordofanian/Adamawa-Ubangui group (P = 0.024). Our study provides the first data on ethnic distribution of ABO and Rhesus blood groups in the Cameroonian population and suggests that its general profile is similar to those of several sub-Saharan African populations. We found some significant differences in phenotypic distribution amongst major ethnolinguistic groups. These data may be important for blood donor recruitment policy and blood transfusion service in Cameroon.

Is There an Association between Keloids and Blood Groups?

Objective. The aim of the study is to investigate the possible associations between the blood groups ABO and Rhesus systems and the presence of keloids in patients with black skin. Method. This case-control study was conducted between September 2007 and August 2011 comparing dermatologic outpatients with keloids to matched controls recruited in preanesthetic consultation at Tokoin Teaching Hospital of Lomé (Togo). Results. The distribution of different ABO blood groups and Rhesus blood groups in both groups (cases versus controls) was not significantly different. This distribution of different blood groups was superimposed on the general population of blood donors at the National Blood Transfusion Center of Lomé. Univariate analysis between each blood group and the presence of keloid does not yield any statistically significant association between blood groups and presence of keloids in the subjects. Conclusion. The study shows no significant association between blood groups and the presence of keloids in our patients. Further investigation needs to be conducted to elucidate this hypothesis further by conducting multicenter studies of several ethnic groups.

PP050. Distribution of ABO and Rhesus blood groups in patients withpre-eclampsia

The ABO-system of antigens and the Rh-system (D-antigen) is genetically determined and remains the most important blood group systems clinically. Several studies have examined the association between ABO and Rhesus blood group systems and pre-eclampsia. At present there is no consensus to define this association, especially not in a Brazilian population. The purpose of the present study was to evaluate the association between pre-eclampsia versus ABO and Rhesus blood group systems in pregnant women hospitalized in a University Hospital in Porto Alegre, Brazil -Hospital São Lucas (HSL). Pre-eclampsia/eclampsia (PE/E) was diagnosed by the National High Blood Pressure Education Program Working Group Report on High Blood Pressure in Pregnancy guidelines. This study consisted of 14,894 pregnant women admitted to the Maternity Department between 2005 and 2010. The patients were reviewed retrospectively for inclusion. Complications in pregnancy not related to pre-eclampsia/eclampsia (PE/E) and those with uncompleted data were excluded. Medical records of 410 women were used to diagnose PE/E. The control group consisted of 8781 women. Each group was subdivided according to their blood groups. In comparison to the PE/E women and controls, no specific relation in blood groups was observed. With respect to ABO and Rh groups, no differences between PE/E and controls were observed (P=0.479 and P=0.169 respectively). When analyzed with both Rh and ABO Pearson Chi-Square also showed no differences (P=0.569). This study aimed to demonstrate some association between blood groups and PE/E using a large sample from the south of Brazil, a population not investigated before. In our study, no specific differences were observed between PE/E and controls in the distribution of the blood groups. In conclusion, the results of this study suggest no association between ABO and Rhesus blood group systems and PE/E in our population. CAPES Foundation-Ministry of Education of Brazil.

ABO and rhesus blood groups among blood donors in Kano, North-Western Nigeria

Background: The need for blood and blood products requires an efficient blood transfusion service. This study was undertaken to provide pro data on the distribution of ABO and Rhesus blood groups that would assist in planning and coordinating blood transfusion services for the cosmopolitan city of Kano. Materials and Methods: A total of 5000 consecutive blood donor samples were grouped for ABO and Rhesus 'D' antigen by tile and tube methods at Aminu Kano Teaching Hospital (AKTH) over a one-year period. Results: Blood group O had the highest prevalence of 2860 (57.2%) followed by blood group B of 1035 (20.7%), then A of 1025 (20.5%) and the lowest being AB of 80 (1.6%). A total of 4741 (94.8%) of the study group were Rhesus 'D' positive while 259 (5.2%) were Rhesus 'D' negative. Conclusion: The ABO blood group had blood group O as the most prevalent blood group in the study population while the lowest was AB. The Rhesus blood group positive was 94.8% while Rhesus negative blood group was 5.2%.

Distribution of ABO and rhesus blood groups among pregnant Bauri women in Bankura district of West Bengal

Distribution of ABO and rhesus blood groups among pregnant Bauri women in Bankura district of West Bengal

Distribution of ABO and Rhesus (RHD) Blood Groups in Al-Jouf Province of the Saudi Arabia

AbstractABO and RHD blood grouping was carried out on 400 Saudi adult male subjects, 100 each from Sakaka, Domaht Al-Jandal, Al-Qurayat and Sweer cities of the Al-Jouf Province of the Saudi Arabia. Finger prick blood samples were tested for both the blood groups by routine slide method. In the total material studied here from the Al-Jouf Province, blood group O was found highest (0.628), followed by A (0.193), B (0.179) and AB (7.3%) while the percentage of RHD Positive (0.705)was greater than RHD negative(0.295). This study could have significant implications for the major blood banks in Al-Jouf area where certain blood groups are needed more than others in emergency conditions. In addition, the data generated would be helpful to the researchers to explore the factors responsible for the observed distribution patterns of the studied blood group systems.

Frequency Distribution of Hemoglobin Variants, ABO and Rhesus Blood Groups among Students of African Descent

Frequency Distribution of Hemoglobin Variants, ABO and Rhesus Blood Groups among Students of African Descent

The distribution of ABO and Rhesus blood groups among indigenes of Ijaw ethnic group in Niger Delta region, Nigeria

The ABO and Rhesus blood group series is the commonest and most important blood group series. In order to determine its distribution among the indigenes of Ijaw ethnic group in Niger Delta Region, Nigeria, a retrospective study of records of blood groupings from 1046 subjects comprising blood donors, blood recipients, patients attending routine antenatal care as well as individuals who presented for routine medical examinations, over a five year period (2005-2009), was done. Overall, blood group O (65.30%) was the highest, followed by blood group B (19.03%), and blood group A (13.57%) while blood group AB (2.10%), was the least. For the Rh (D) distribution, 95.70% were Rhpositive while 4.30% were Rh-negative. The distributions, according to gender, as well as according to site of study, follow the same trend as that of the general studied population. The results from this study will be useful to health planners and service providers.KEY WORDS: Blood group, Ijaw, Ethnic, Nigeria.

ABO and rhesus blood group distribution in Kurds

It is well established that ABO and rhesus (Rh) genes and phenotypes vary widely between ethnic groups and both within and between geographical areas. The aim of this study was to determine the distribution of ABO and Rh blood groups in Kurds and to compare it with those of other populations. The study included blood grouping of total population of 53,234 whose ABO and Rh blood groups were determined by standard methods during a period of about 5 years (2005-2009). The most prevalent blood group was O (37.16%), followed by blood groups A (32.47%) and B (23.84%), whereas the least prevalent blood group was AB (6.53%). The majority 91.73% were Rh positive, and 8.27% were Rh negative. Data showed that among the Rh-positive individuals, 34.03% were O, 29.99% were A, 21.69% were B, and 6.02% were AB. Break up of the Rh negatives showed that 3.13% were group O, 2.48% were A, 2.15% were B, and 0.51% were AB. Blood group O is the commonest blood group in, followed by A, B, and AB. More than 91% of the study population is Rh positive. Also, we can conclude that distribution of ABO and Rh blood groups in Kurds, in addition to being close to the mean of the world's population, is closest to Iranians, with similar trend to the neighboring countries, and appears to be intermediate between eastern (Asian) and western European (Caucasian) data.

Abnormal hemoglobin variants, ABO, and Rhesus blood group distribution among students in the Niger Delta of Nigeria

Abnormal hemoglobin variants, ABO, and Rhesus blood group distribution among students in the Niger Delta of Nigeria O Erhabor1, TC Adias2, Z A Jeremiah1, M L Hart21Department of Medical Laboratory Sciences, College of Health Sciences, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria; 2Department of Medical Laboratory Sciences, Rivers State University of Science and Technology, Port Harcourt, NigeriaBackground: Communities in Africa constitute a major part of the population that is vulnerable to many erythrocytic hereditary and hematological disorders such as hemoglobinopathies. The frequencies of abnormal hemoglobin variants, ABO, and Rhesus blood groups vary from one population to another.Methods: The aim of this study was to find the prevalence/spectrum of hemoglobin variants, ABO, and Rhesus blood group distribution among 204 undergraduate students of African descent in Port Harcourt in the heart of the Niger Delta geopolitical zone of Nigeria. Standard alkaline cellulose acetate electrophoretic technique using the Shandon electrophoretic tank with tris-ethylene diamine tetracetic acid (EDTA) borate buffer and hemagglutination techniques were employed for the determination of abnormal hemoglobin variants, ABO and Rhesus blood groups, respectively. Results: Two hundred and four apparently healthy students of African descent comprising 124 males (60.8%) and 80 (39.2%) females with a mean age 24.5 &plusmn; 6.5 years took part in the study. Subjects were screened for abnormal hemoglobin variants, ABO, and Rhesus groups. Normal hemoglobin accounted for 69.1%, followed by abnormal sickle cell trait in 29.4%, and the sickle cell disease in 1.5% of the study population. The distribution of the various blood groups indicated that 46% were blood group O, 26.6% were group A, 23.6% were group B while 3.8% were group AB. Rhesus (RhD) positivity rate was 93% while RhD negativity accounted for 7%.Conclusion: This research indicates a high prevalence of hemoglobin variants in the study population. Carrier screening and mutation identification can become the cornerstones of any prevention program for hemoglobin disorders. It can also help in the formulation of genetic counseling policies to help prospective couples make informed decisions in a bid to reduce the sickling gene pool in the Niger Delta of Nigeria.Keywords: abnormal hemoglobin variants, ABO, Rhesus blood group, Niger Delta, Nigeria

ABO blood groups, rhesus factor and pemphigus

Background: Pemphigus is an autoimmune blistering disease of the skin and mucous membranes with significant mortality and morbidity. Genetic factors are known to be involved in pemphigus. Several studies have reproducibly shown significant associations of ABO blood groups with various autoimmune human diseases. Aim: To study the relationship between ABO and Rhesus (D) blood groups and pemphigus in Iranian patients. Materials and Methods: Data on age, sex, ABO and Rhesus blood type and clinicopathological diagnosis of the patients with pemphigus were collected. A total of 573 patients with pemphigus were assessed for their association with ABO or Rhesus (D) blood groups and compared with the normal population in the area. Results: The distribution of ABO and Rhesus blood groups in patients with pemphigus was similar to the normal local population in Iran. No relationship was found between ABO or Rhesus blood groups and the phenotype of pemphigus. Conclusion: It appears that there is no association between ABO or Rhesus (D) blood groups and the frequency of pemphigus variants in comparison with normal population in Iran.

Distribution of abo and rhesus blood groups in University of Uyo Teaching Hospital (UUTH), Uyo, Nigeria

Background: The University of Uyo Teaching Hospital (UUTH), Uyo is a tertiary health institution which serves the health needs of the people of Akwa Ibom State and beyond. Blood transfusion service is one of the most important health services provided by UUTH. Organized, efficient and safe blood transfusion practice needs data in blood group serology. This study was carried out because of lack of research based data on human blood group system in UUTH, Uyo and Akwa Ibom State. Materials and Method: The study is retrospective. Patients' ABO and Rhesus blood group registers in the blood bank of UUTH, Uyo, were reviewed from the year 2000 (when in 2000?) 31st May 2006. The total number reviewed was 10,552.Results: From the 10,552 patients records reviewed for the ABO blood group, blood group O was the the most common with 5,919 (56.10%), followed by blood group A with 2,645 (25.07%), while blood group B was third with 1,728(16.386) and lastly blood group AB with 259 (2.45%). The distribution of Rhesus antigen shows that Rhesus D positive was the highest with 10,203 (96.68%) while Rhesus D Negative was the lowest with 349 (3.30%).&#x0D; Conclusion: The baseline data from this study which is in keeping with the observed trend in other studies in Nigeria, hopefully, would assist in the planning and running of an organized, efficient and safe blood transfusion service in UUTH, Uyo and in Akwa Ibom State, Nigeria.

Distribution of abo and rhesus (D) blood groups in Kano metropolis

Background : To provide information in the distribution of ABO and Rhesus (D) blood groups since there has been no such study carried out in Kano. Study Population/Method : A total of 5,303 blood donors and pregnant women who came for antenatal care at Aminu Kano Teaching Hospital, Kano between January and December, 2003 were determined by Dacie and Lewis method. Result : Blood group O had the highest distribution of 55.3%, followed by similar result of 20.8% and 207% of blood groups A and B respectively while blood group AB had the lowest distribution of 3.2%. The prevalence of Rh(D) negative subjects amongst the population studied was 5.1%. Similar result were obtained when the distribution of A Rh (D) positive, A Rh (D) negative, B Rh (D) positive, B Rh(D) negative, O Rh(D)positive and O Rh (D)negative(20.1%, 1.3%, 19.6%,1.1%, 50% and 2.3% respectively) of pregnant women were compared to 19.6%, 0.83%, 19.7%, 1.0%, 53.9%,and 3.% respectively of blood donor. However, striking differences were observed when AB Rhesus (D) positive (5.4%) and AB Rh(D) negative (0.24%) of pregnant women were compared to 1.6% and 0.1% respectively of blood donors. Conclusion : Similar result of ABO and Rhesus (D)blood groups distribution have been observed in this study when compared to previous studies in Nigeria. However, there is a need for further study to be carried out with regard to tribes since ethnicity and inter-tribal marriage have been found by earlier authors to influence the ABO and Rhesus blood groups distribution most especially in the urban areas. Keywords : distribution, ABO and rhesus (D) groups, Kano Highland Medical Research Journal Vol. 3(2) 2005: 139-143

Abo And Rhesus Blood Groups Distribution In Mothers And Neonates In A Nigerian Population

Objective: To provide information in the distribution of ABO and Rhesus Blood Group in our population. Study Population/Methods: One hundred and twenty one antenatal mothers who were sequentially booked in antenatal care clinic of University of Jos Health Clinic, Jos, Plateau State after their informed consent. Cord blood was obtained from the babies of these mothers at birth. ABO and Rhesus blood groups were determined by Dacie and Lewis Methods. Result: Blood group O is the most common blood group representing 74% and 75% in mothers and their babies respectively. The distribution of group B is 13% in mothers and 12% in their babies. The distribution of A and AB groups among mothers and their babies is 10% and 3% respectively. There is a 100% Rhesus positivity in both mothers and neonates. Conclusion: The Rhesus negativity is very rare. There should still be need to test intending to marry couples before they start having children. Key words: Maternal, Umbilical Cord Blood, ABO & Rhesus blood groups. Highland Medical Research Journal Vol.1(1) 2002: 11-12

Gene frequencies of abo and rhesus blood groups and haemoglobin variants in ogbomoso, South – West Nigeria

The distribution and gene frequencies of ABO and Rhesus (Rh) blood groups and haemoglobin variants for samples of the Nigerian population at Ogbomoso, was determined. Data consisting of records of blood groups and haemoglobin types of different ages ranging from infants to adults for a period of 4 to 6 years (1995 – 2000) was collected from Baptist Medical Centre (BMC), Ladoke Akintola University of Technology Health Centre (LAUTHC) and Oyo State General Hospital (OSGH), all in Ogbomoso, Oyo State, Nigeria. Overall, a total number of 7653, 7053 and 14,845 individuals were typed for ABO and Rh blood groups; and haemoglobin genotypes, respectively. 3824 (50 %) were blood group O, 1750 (22.9 %) were blood group A, 1629 (21.3 %) were blood group B and 450 (5.9 %) were blood group AB. This distribution differs significantly (P AS (21.0 %) > AC (5.7 %) >SS (3.0 %) >SC (2.0 %) >CC (0.3 %). The gene frequencies were 0.81, 0.14 and 0.04 for A, S and C alleles, respectively. Our results are representative of the distribution of these genetic variants in Nigeria. (Global Journal of Medical Science, 2004, 3 (1&2): 17-22)

Distribution of Rhesus Blood Group System in the French Basques: A Reappraisal Using the Allele-Specific Primers PCR Method

Objectives: To determine for the first time using PCR the distribution of Rhesus (Rh) blood group in French Basques and compare these results with those obtained by serology in the same sample and in the historical series from various Basque subgroups. Methods: Rh polymorphism was determined in a sample of 127 autochthonous French Basques using allele-specific primers (ASP) PCR and traditional serological technique. Statistical comparisons were performed between both techniques and with the data published from various Basque subpopulations. Results: No intra-sample discrepancies were detected between ASP-PCR and serology. A high frequency of RH Ddel exceeding 0.50, as typically described from several decades, was found here (0.511), as the peculiar frequency of cde (0.456) and cDE (0.073) haplotypes. This profile, obtained by molecular analysis, was within the range of previous historical studies in various Basque subpopulations using serological approach. The Rh polymorphism among the reviewed autochthonous Basque samples indicates a heterogeneous pattern of distribution, with individuals from the Alava province demonstrating the most atypical profile. Conclusions: Molecular biology approach using PCR confirms the peculiar pattern of Rh polymorphism which was previously defined by serology among Basques. Nevertheless, this distribution profile is not homogeneous within the Basque area.

ABO and Rh (D) Blood Groups Among the Telugu Speaking Fishing Community of Andhra Pradesh

Anthropologists have used ABO and Rh blood group systems for the determination of frequencies of blood group alleles in human populations and with the help of these they have not only attempted the analysis of the history of populations but also used them to study the action of natural selection. Further, blood group systems are useful in determine the genetic variation within and between the populations. During the last four decades, numerous studies have been carried out on the genetic composition of various endogamous population groups in India (Bhasin et al., 1992;1994). However, genetic studies among fishing communities in India are very limited. Hence, in the present study the distribution of ABO and Rhesus blood groups has been reported among the Telugu speaking marine fishing community of coastal Andhra Pradesh.

Genetic studies among seven endogamous populations of the Koshi Zone, Bihar (India)

The distribution of AB0 and Rhesus blood groups, PTC taste sensitivity and colour blindness was studied among seven endogamous populations (Tharu, Mushar, Santal, Dhobi, Julaha, Kulhaiya and Karan Kayastha) in the Koshi Zone of Bihar (India). The phenotype and allele frequencies of the four gene loci (AB0, RH, PTC and colour blindness) show considerable differences between these populations. The measurement of genetic distances revealed, that the lowest genetic distance is seen between Dhobi and Julaha, the highest between Mushar and Tharu. From the genetic distance analysis there is some evidence for a close genetic relationship among the population groups belonging to the same region, irrespective of their caste, religion, linguistic or any other affinities. It may be concluded that all these populations have arisen through a common ancestor and changed gene frequencies among them is due to evolutionary forces like mutation, selection, migration, temporal variation and genetic drift. However, these populations retain their separate entities by practising endogamy. Gene diversity analysis reveals that these populations are at an early stage of genetic differentiation.

Distribution of ABO and Rhesus Blood Groups among Lotha-Nagas of Nagaland

Distribution of ABO and Rhesus Blood Groups among Lotha-Nagas of Nagaland