Review question/objective The overall objective of this systematic review is to identify, critically appraise and synthesize the literature regarding the experiences of new graduate nurses working in a pediatric setting. The specific review question is: what are the experiences of new graduate nurses working in a paediatric setting? Inclusion criteria Types of participants This systematic review will consider studies involving new graduate nurses of any age, gender and cultural background working for 12 months or less in a pediatric setting. A new graduate nurse is a person who has completed a baccalaureate course, associate degree, diploma or equivalent course in nursing, has qualified for registration and is working within the first year post registration as a registered nurse. Phenomena of interest This systematic review will consider studies that investigate the experiences of new graduate nurses working in a pediatric setting. The experiences include new graduate nurses’ perceptions, perspectives, views, challenges, feelings, beliefs and thoughts of working within the first year post registration in a pediatric setting. The experiences may include, but are not limited to, communication, advocacy, education and minimization of distress in dealing with patients and their families. Context Any pediatric setting including, but not limited to, hospitals of any size and within the community in any country, excluding neonatal intensive care units and special care nurseries. A pediatric setting is a place where care is provided to sick infants, children and adolescents.