Review Panel Research Articles

Evaluating the effectiveness of the Complex Behaviour Forum—A multisystem approach to supporting people with complex challenging behaviour

AbstractBackgroundThis study assessed the effectiveness of a cross‐departmental case review panel—the Multicap Complex Behaviour Forum (CBF)—in reducing challenging behaviour exhibited by people with intellectual disabilities.MethodsThirty participants (15 CBF participants and 15 matched‐control participants) took part in the study. Behavioural data was collected for each CBF participant (and their matched control) for the three‐month period before entering the CBF, during their time in the CBF, and the 3 months after exiting the CBF.ResultsThere was a significant interaction of group and time observed, with the CBF participants showing more change in behavioural incidents across time. Associated with this change was a noticeable reduction in staff injury costs related to the challenging behaviour of the CBF participants.ConclusionsThis study demonstrates that positive behavioural and organisational outcomes are enhanced by fostering collaboration across multiple organisational systems when it comes to supporting people who exhibit challenging behaviours.

Dealing with potentials and drawbacks of peer review panels: About the intertwined layers of determinacy and indeterminacy

Dealing with potentials and drawbacks of peer review panels: About the intertwined layers of determinacy and indeterminacy

Oncologists' Satisfaction with Virtual Care: A Questionnaire.

Although virtual care (VC) has become an integral part of oncology care and healthcare delivery, clinicians' perspectives on and satisfaction with this modality are not well understood. Using a National Network Forum framework and expert panel review, we developed a questionnaire to measure oncologists' satisfaction with VC. The questionnaire was distributed to Canadian oncologists through medical society email lists (n = 1541). We used a 5-point Likert scale to capture their responses, which included strongly disagree (1), disagree (2), undecided (3), agree (4), and strongly agree (5). A total of 61 oncologists and/or oncology trainees, of 768 (7.9%) who opened their email, completed questionnaires between October 2022 and January 2023. Every questionnaire item had a response rate greater than 98%. Seventy-two percent of the respondents were satisfied with VC. Oncologists who were less comfortable with technology were more likely to report lower levels of satisfaction (p < 0.001, Wilcoxon rank-sum). The questionnaire items that received the highest levels of agreement were related to VC reducing costs and improving access for patients and concerns about missing a diagnosis and assessing patients' functional status. The questionnaire items that received the greatest disagreement were related to VC improving access for patients with language barriers, VC being associated with time-savings for clinicians, improvements in clinical efficacy, and more readily available lab tests. Most of the oncologists surveyed are satisfied with VC; however, there are some concerns with VC that need to be addressed. Future research on optimizing VC should address clinicians' concerns, in addition to addressing the patient experience.

Provisions for nullification of conservation and management measures in RFMO objection procedures

In order to successfully exercise their mandate to adopt binding conservation and management measures (CMMs) for straddling and highly migratory fish stocks, regional fisheries management organizations (RFMOs) and arrangements (RFMAs) need effective decision-making procedures. The constitutive instruments of a considerable number of such bodies contain objection procedures which allow individual members to unilaterally opt-out of an adopted CMM. Most scholars and RFMO performance review panels consider that unconstrained unilateral objection procedures undermine the decision-making procedures of both RFMOs and RFMAs. This article examines the phenomenon of CMM nullification provisions, which are present in five RFMOs. Such provisions deprive adopted CMMs of their binding force for all members if a certain number of members of the RFMO object to the CMM. This article argues that there is a case for a phase-out of CMM nullification provisions together with the unilateral objection procedures to which they are closely tied. Compared to unilateral objections more generally, CMM nullification provisions raise additional legitimacy questions given that they result in the nullification of CMMs that have been democratically adopted in conformity with the legitimate decision-making procedures of the respective RFMO. This article first provides a brief overview of the rationale for objection procedures by placing the concept of objections in the broader context of RFMO decision-making. Thereafter, this article briefly examines the requirements and legal effects of individual objections of RFMO members to CMMs. The final substantive section analyzes and compares existing CMM nullification provisions, focusing on the requirements for their activation, the nature of their legal effects and the legitimacy of such procedures considering the broader decision-making procedures of individual RFMOs.

The Development of Instructional Considerations for Using Augmented Reality (AR) in Light of the Principles of Constructivism Learning Theory in Social Studies Classrooms

Objectives: There is a growing interest in embedding virtual technology such as Augmented Reality (AR) into social studies classrooms. Unfortunately, many social studies teachers struggle with technology in general, including AR-aided learning. Method: To help them learn how to employ AR technology effectively, this study used the ADDIE model to develop a set of AR instructional considerations based upon constructivist learning theory. Results: The authors validated this work via two rounds of expert panel review in four different domains: instructional design and development, technology-based theory in social studies classrooms, AR technology and education, and teaching social studies. In all, twelve experts reviewed the considerations, answering detailed, open-ended survey questions in round 1, and completed a rubric in round two. Conclusion: The resulting consideration set, should provide useful guidance for social studies teachers to integrate AR technology into their classroom practice.

Management of unscheduled bleeding on HRT: A joint guideline on behalf of the British Menopause Society, Royal College Obstetricians and Gynaecologists, British Gynaecological Cancer Society, British Society for Gynaecological Endoscopy, Faculty of Sexual and Reproductive Health, Royal College of General Practitioners and Getting it Right First Time.

Unscheduled bleeding on hormone replacement therapy (HRT) can affect up to 40% of users. In parallel with the increase in HRT prescribing in the UK, there has been an associated increase in referrals to the urgent suspicion of cancer pathway for unscheduled bleeding. On behalf of the British Menopause Society (BMS) an expert review panel was established, including primary and secondary care clinicians with expertise in the management of menopause, with representatives from key related organisations, including the Royal College of Obstetricians & Gynaecologists, the British Gynaecological Cancer Society, British Society for Gynaecological Endoscopy, Royal College of General Practitioners and Faculty of Sexual and Reproductive Health, and service development partners from NHS England and GIRFT (Getting it Right First Time). For each topic, a focused literature review was completed to develop evidence led recommendations, where available, which were ratified by consensus review within the panel and by guideline groups.

Standardised protocol for a prospective international multicentre clinical-based evaluation of point-of-care tests for the screening of genital and extragenital chlamydial and gonococcal infections in men who have sex with men and for the screening of genital chlamydial, gonococcal and Trichomonas vaginalis infections in at risk women

IntroductionIn 2016, WHO estimated there were roughly 374 million new infections among adults of the following four curable sexually transmitted infections (STIs): chlamydia (caused by Chlamydia trachomatis (CT)), gonorrhoea (Neisseria...

Systematic Screening and Assessment of Hospital-Based Youth Violence Prevention Programs.

Youth violence is a preventable public health issue. Few hospital-based programs intentionally focus on youth violence prevention. This project aimed to describe the Systematic Screening and Assessment (SSA) methodology used to identify existing hospital-based youth violence prevention (HBYVP) programs ready for future rigorous evaluation. To identify promising HBYVP programs currently in use and assess readiness for evaluation, data from the 2017 American Hospital Association (AHA) Annual Survey of Hospitals was used to identify hospitals with Level I-III trauma centers with reported HBYVP programs. Information for each program was gathered via environmental scan and key informant interviews. A total of 383 hospital-based violence prevention programs were identified. Two review panels were conducted with violence prevention experts to identify characteristics of programs suitable for an evaluability assessment (EA). Fifteen programs focused on youth (10-24 years old) and were identified to be promising and evaluable. Three of the 15 programs were determined to have the infrastructure and readiness necessary for rigorous evaluation. Lessons learned and best practices for SSA project success included use of streamlined outreach efforts that provide program staff with informative and culturally tailored project materials outlining information about the problem, project goals, proposed SSA activities, and altruistic benefit to the community at the initial point of contact. In addition, success of review panels was attributed to use of software to streamline panelist review processes and use of evaluation and data analysis subject matter experts to serve as panel facilitators. Communities experiencing high youth violence burden and hospitals serving these communities can improve health outcomes among youth by implementing and evaluating tailored HBYVP programs.

The regulation of alien species in South Africa

A key global change challenge is to significantly reduce the risks of alien taxa causing harmful impacts without compromising the rights of citizens. As part of efforts to address this challenge, South Africa promulgated comprehensive regulations and lists of alien taxa in 2014. In this paper, we review how the lists developed, changed over time, and how they have been implemented. As of March 2021, 560 taxa were listed under four broad regulatory categories, and between 2014 and 2020, almost 3000 permits were issued to regulate the continued use of listed taxa. The full lists of regulated taxa, permits issued, and corresponding regulations are available in the Supplementary material. A proposed standardised, transparent, and science-informed process to revise the regulatory lists is also presented – as of 30 April 2024, risk analyses have been developed for 140 taxa using the Risk Analysis for Alien Taxa (RAAT) framework and reviewed by an independent scientific body [the Alien Species Risk Analysis Review Panel (ASRARP)] with input from taxon-specific experts. These recommendations are being considered by an interdepartmental governmental decision-making body established in March 2023 [the Risk Analysis Review Committee (RARC)]. Finally, key issues with the listing of alien taxa in South Africa that remain to be resolved are presented. As South Africa’s regulatory framework continues to develop, the process of listing and regulating alien taxa will, we believe, become more transparent, consistent, and acceptable to stakeholders, and ultimately facilitate efforts to reduce the harmful impacts of alien taxa.

Cholestasis in Chronic Liver Disease and the Role of Ademetionine in its Treatment (Literature Review and Expert Panel Resolution)

Aim: to analyse the principles of diagnosis and treatment of intrahepatic cholestasis in chronic liver diseases, to present data on the effectiveness of ademetionine in the treatment of chronic liver diseases with intrahepatic cholestasis and the materials of the Expert Meeting held in 2023. Key points. During the Expert Meeting, the problems of diagnostics and treatment of intrahepatic cholestasis in various chronic liver diseases were discussed, the effectiveness of ademetionine was clarified, and optimal regimens for its administration were determined. The relevance of the existing algorithm for diagnosing cholestasis in real clinical practice was assessed. The effectiveness of ademetionine in the treatment of various liver diseases occurring with intrahepatic cholestasis (cholestatic forms of drug-induced liver damage, alcoholic liver disease, non-alcoholic liver disease, primary biliary cholangitis) was demonstrated, manifested by a decrease in clinical and laboratory signs of cholestasis. The anticholestatic mechanisms of ademetionine action were clarified, which consist in normalizing the fluidity of hepatocyte membranes, regulating the activity of Nrf2, a key transcription factor, suppressing lipid peroxidation and the resulting damage to hepatocytes and cholangiocytes. Optimal regimens for prescribing ademetionine for various clinical situations were considered. Conclusions. Ademetionine is an effective drug that, due to its pleiotropic action and favourable safety profile, can be used in various chronic liver diseases accompanied by cholestasis, including as a part of the complex therapy.

Analysis of Bovine Lactoferrin in Infant Formula and Adult Nutritional Products by Optical Biosensor Immunoassay: Collaborative Study, Final Action 2021.07.

Bovine lactoferrin is increasingly being used as an ingredient in infant formula manufacture to enhance nutritional efficacy through the provision of growth, immunoprotective, and antimicrobial factors to the neonate. To evaluate method reproducibility of AOAC First Action Official Method 2021.07 for compliance with the performance requirements described in Standard Method Performance Requirement (SMPR®) 2020.005. Eight laboratories participated in the analysis of blind-duplicate samples of seven nutritional products. Samples were diluted in buffer, and an optical biosensor immunoassay was used in a direct-assay format to quantitate bovine lactoferrin by its interaction with an immobilized anti-lactoferrin antibody. Quantitation was accomplished by the external standard technique with interpolation from a four-parameter calibration regression. After outliers were removed, precision as reproducibility was found to be within limits set in SMPR 2020.005 (≤ 9%) for six out of seven samples and all had acceptable Horwitz Ratio (HorRatR) values ranging from 1.0 to 2.1. Additionally, comparison with an alternative independent Stakeholder Panel on Infant Formula and Adult Nutritionals (SPIFAN) First Action method (heparin cleanup LC-UV), showed negligible difference between results. The method described is suitable for the quantification of intact, undenatured bovine lactoferrin in powdered infant formulas. The SPIFAN Expert Review Panel evaluated the method and accompanying validation data from this multi-laboratory testing (MLT) study in July 2023 and recommended Official Method 2021.07 for adoption as a Final Action Official MethodSM. A multi-laboratory validation study of an automated optical biosensor immunoassay for the determination of intact, undenatured bovine lactoferrin is described.

Nurses' knowledge, attitudes and practices regarding the application of the injury severity score in emergency departments: A cross-sectional multicentre study.

To investigate knowledge, attitudes, and practices regarding the application of the Injury Severity Score (ISS) among emergency department nurses in China and the factors influencing these variables. ISS is the first trauma scoring method to be developed and the most widely used in clinical practice. The correct application of the ISS by emergency department nurses plays an important role in assisting in the diagnosis and treatment of trauma patients, and it is crucial to understand nurses' knowledge, attitudes and practices. A cross-sectional multicentre study. Nurses from the emergency departments of 25 grade II and grade III hospitals in Gansu Province, China participated in this study. Data was collected online using a self-administered questionnaire. Student's t-test or analysis of variance was performed to compare the differences between the groups. Multiple logistic regression analysis identified factors influencing nurses' knowledge, attitudes and practices regarding applying ISS. A STROBE checklist was used to report findings. Among 459 nurses, a good level of attitude and passing levels of knowledge and practice regarding applying the ISS were revealed. Nurses in higher hospital grades, who had been exposed to ISS and received training had higher levels of knowledge and practices. Previous exposure to the ISS and training related to it were factors that influenced nurses' attitudes. Chinese emergency department nurses' knowledge, attitudes and practices of applying the ISS still need to be improved. Hospitals and nursing managers should provide training opportunities for nurses about ISS knowledge and practices, while grade II hospitals should pay more attention to training and continuing education in this area. In hospitals, nursing managers may benefit from enhancing related education and training to promote the emergency department nurses' knowledge and practice of the ISS, by developing specific curricula and providing continuing education and training opportunities, while grade II hospitals should pay more attention to training and continuing education in this area. This study focused on emergency department nurses' knowledge, attitudes, and practices regarding the application of the ISS. The research questions and design were derived from clinical nursing practice, literature review, and expert panel review, and patients or the public are temporarily not involved.

Acknowledgement of Members of Pedagogy in Health Promotion: The Scholarship of Teaching and Learning’s Review Panel

Acknowledgement of Members of <i>Pedagogy in Health Promotion: The Scholarship of Teaching and Learning</i>’s Review Panel

Applying PEOP to Develop an Intervention Framework for Employment in Parkinson's Disease.

Employment intervention is essential for supporting people with Parkinson's disease (PwPD), who leave the workforce on average 5 years earlier than those without Parkinson's disease (PD). We developed a framework for occupational therapists (OTs) to address employment for PwPD. Our qualitative analysis employed data source triangulation of environmental scan of resources and publications, electronic medical records data, and focus groups with clinicians and PwPD. The framework underwent expert panel review by OTs and researchers who are knowledgeable of current evidence-based practices for PD. The framework is based on the Person-Environment-Occupation-Performance (PEOP) Model and PEOP Occupational Therapy Process and comprised of four parts: PEOP features of PD relevant to employment, performance changes experienced by PwPD, a process to evaluate and address employment, and intervention ideas. This framework serves as an impetus to explore evidence-based, scalable, proactive intervention approaches to address employment in PwPD.

Dutch translation and cultural adaptation of new LYMPH-Q- scales measuring impact on work and lymphedema worry

BackgroundBreast cancer-related lymphedema (BCRL) is a significant complication of breast cancer treatment that can impact patients’ quality of life. This study focuses on the translation and cultural adaptation of two new LYMPH-Q scales ‘Impact on Work’ and ‘Lymphedema worry’ into Dutch to assess the work-related challenges and worries experienced by patients with BCRL in the Netherlands.MethodsThe translation process followed established guidelines from the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) and the World Health Organization (WHO). Forward and back translations, expert panel reviews, cognitive debriefing interviews with patients with BCRL, and proofreading were conducted to refine the Dutch translation of the scales. The translation aimed to ensure conceptual equivalence and cultural relevance.ResultsThe translation process resulted in the Dutch versions of the LYMPH-Q ‘Impact on Work’ and ‘Lymphedema worry’ scales. The forward translation revealed discrepancies in meaning, word order and synonyms. The back translation and review resulted in changes in item formulation. The expert panel meeting and cognitive debriefing interviews provided valuable input for further refinement.ConclusionThe translated LYMPH-Q ‘Impact on Work’ and ‘Lymphedema worry’ scales provide healthcare professionals with an instrument to assess and monitor the impact of BCRL on work-related challenges and on worries. This comprehensive translation process, involving patients with BCRL and experts, ensured the linguistic accuracy, cultural relevance, and clarity of the Dutch versions. The translated scales will contribute to a better understanding of the multifaceted impact of BCRL and facilitate the development of tailored interventions to improve patients’ well-being and functional outcomes.Level of Evidence:Not ratable

Comparing types of child fatality review in the U.S.

Child fatality review programs consist of multidisciplinary teams of professionals, agencies and community members with an interest in caring for and protecting children. While the purpose of all child fatality reviews is to conduct a comprehensive, multidisciplinary review of child fatalities to better understand how and why children die, there are distinct types of reviews in the United States that each use findings to take action to prevent other fatalities and improve the health and safety of children in different ways. Each brings a unique perspective, incorporating different stakeholders and methodologies and playing different roles in identifying patterns, gaps in services, and potential areas for improvement within the broader context of child health and safety. Three major types of review now consistently used across the U.S. include Child Death Review, Fetal Infant Mortality Review, and Citizen Review Panels. These differ in their history of development, statutory authority, financial support, nature of cases reviewed, processes, and reporting to stakeholders. This article is an introduction to the major different types of community-based death review to help practitioners understand and participate more productively in these processes to prevent further fatalities.

Preventable trauma deaths in the Western Cape of South Africa: A consensus-based panel review.

Injury causes 4.4 million deaths worldwide annually. 90% of all injury-related deaths occur in low-and-middle income countries. Findings from expert-led trauma death reviews can inform strategies to reduce trauma deaths. A cohort of trauma decedents was identified from an on-going study in the Western Cape Province of South Africa. For each case, demographics, injury characteristics, time and location of death and postmortem findings were collected. An expert multidisciplinary panel of reviewed each case, determined preventability and made recommendations for improvement. Analysis of preventable and non-preventable cases was performed using Chi-square, Fisher's exact, and Wilcoxon signed rank tests. A rapid qualitative analysis of recommendations was conducted and descriptively summarized. 138 deaths (48 deceased-on-scene and 90 pre- or in-hospital deaths) were presented to 23 panelists. Overall, 46 (33%) of deaths reviewed were considered preventable or potentially preventable. Of all pre- and in-hospital deaths, late deaths (>24 hours) were more frequently preventable (22, 56%) and due to multi-organ failure and sepsis, compared to early deaths (≤24 hours) with 32 (63%) that were non-preventable and due to central nervous system injury and haemorrhage. 45% of pre and in-hospital deaths were preventable or potentially preventable. The expert panel recommended strengthening community based primary prevention strategies for reducing interpersonal violence alongside health system improvements to facilitate high quality care. For the health system the panel's key recommendations included improving team-based care, adherence to trauma protocols, timely access to radiology, trauma specialists, operative and critical care.

Development and validation of a job aid: Tool to reduce infections in home-based stroke.

Stroke patients who are discharged from hospital because of limited access to rehabilitation facilities are cared for by lay caregivers who at times have limited knowledge of infection prevention and control (IPC). User-friendly educational interventions can help bridge this knowledge gap and enhance safe care of these persons. To describe the development and validation of educational interventions for home-based stroke patients. The validation process enhanced the reliability and validity of the job aid resulting in standardised quality patient care of stroke patients. Mutasa district, Manicaland province, Zimbabwe. The systematic six steps in quality intervention development guided the development of the job aid. Graphic designers assisted with development of diagrams and annotations. A purposively selected eight-member panel of IPC expert reviewers was invited to validate the job aid using a standardised validation tool. The panel agreed that the job aid's title, target group and media of instruction were adequately explained, and the background could be easily understood during practice. The content was approved with some modifications on the description of instructions to caregivers. Seven reviewers agreed that the materials used ensured understandability, acceptability, practicability and usability of the educational interventions by caregivers, and one reviewer was neutral in commenting effectiveness of the job aid. The developed job aid addressed knowledge barriers in IPC for caregivers, and the reviewers confirmed that the developed job aid was adequate for effective use by lay home-based caregivers.Contribution:Utilisation of this intervention standardises patient care practices.

224 Influence of gender on animal science research funding from the National Institute of Food and Agriculture

Abstract According to the National Academies of Sciences, Engineering, and Medicine, females and males in science disciplines obtain bachelor of science degrees at or near parity, yet females are not equally represented in academic faculty positions. This is true for agricultural field including the animal sciences. The National Institute of Food and Agriculture (NIFA) administers the Agriculture and Food Research Initiative (AFRI) at USDA, a flagship competitive grants program that fund research, education, and extension efforts with a total appropriation of $455 million in 2023. Our objective was to determine the difference between genders for submission rates (i.e., number of standard and seed grant applications submitted), success rates (i.e., number of grant award/number of applications submitted), and peer reviewers of grant applications in the main animal related AFRI program area priorities. All applications submitted to AFRI programs in animal genomics, reproduction, health, nutrition and growth, and welfare during 2013 to 2022 were evaluated. Gender was assigned to Project Directors (PD) and peer reviewers using first names as input into Gender API software (Gender-API.com; Passau, Germany) with ≥ 95% accuracy and ≥ 20 database occurrences used as quality filters and binary outcomes only (i.e., male or female). Effect of gender on submission rates, success rates, and peer review panel compositions were then analyzed using Pearson’s Chi-squared tests with P ≤ 0.05 considered significant. A total of 3,392 applications were submitted, of which 2,579 (76%) PD genders were assigned and analyzed further. Overall, the proportional submission rate for females was 28% and for males was 72%. Submission rates for females increased (P = 0.0497) over time ranging from 22% in 2013 to 33% in 2021. Submission rates differed by gender across programs (P &amp;lt; 0.0001) and ranged from 22% female in animal reproduction to 48% female in animal welfare. Overall, the funding success rate was 22% and did not differ between genders (P = 0.9826). Success rates did not differ between genders over time (P = 0.4691), but differences among programs approached significance (P = 0.0670). Across 53 panels, 42% of panelists were female; no differences were identified for the proportion of female panelists over time (P = 0.9762) or by program (P = 0.7028). Females submitted less than one-half as many applications as males, but the proportion of submissions by females increased over time. This trend remained consistent despite challenges of relocation of NIFA and COVID-19 during this time. Funding success rates did not differ by gender, but some variation was observed across programs. Overall, the proportion of NIFA panelists who were female exceeded the proportion of applications submitted by females. These results indicate that although differences in gender existed for application submission rate and panel composition, these differences did not impact funding success rate of applications in animal science programs at NIFA, which did not differ between genders.

Guidelines for peer reviewers

Have you ever considered becoming a peer reviewer? In this issue, we provide the Journal of Paramedic Practice guidelines for peer reviewers. Have a read and contact the editor with your CV if you think you want to join the JPP peer reviewer panel