Reversal Frequency Research Articles

Intensity of the Earth's magnetic field: Evidence for a Mid-Paleozoic dipole low

The Mesozoic Dipole Low (MDL) is a period, covering at least ∼80 My, of low dipole moment that ended at the start of the Cretaceous Normal Superchron. Recent studies of Devonian age Siberian localities identified similarly low field values a few tens of million years prior to the Permo-Carboniferous Reverse Superchron (PCRS). To constrain the length and timing of this potential dipole low, this study presents paleointensity estimates from Strathmore (∼411 to 416 Ma) and Kinghorn (∼332 Ma) lava flows, United Kingdom. Both localities have been studied for paleomagnetic poles (Q values of 6 to 7), and the sites were assessed for their suitability for paleointensity from paleodirections, rock magnetic analysis, and microscopy. Thermal and microwave experiments were used to determine site mean paleointensity estimates of ∼3 to 51 μT (6 to 98 ZAm2) and 4 to 11 μT (9 to 27 ZAm2) from the Strathmore and Kinghorn localities, respectively. These, and all the sites from 200 to 500 Ma from the (updated) Paleointensity database (PINT15), were assessed using the Qualitative Paleointensity criteria (QPI). The procurement of reliable (QPI ≥ 5) weak paleointensity estimates from this and other studies indicates a period of low dipole moment (median field strength of 17 ZAm2) from 332 to 416 Ma. This "Mid-Paleozoic Dipole Low (MPDL)" bears a number of similarities to the MDL, including the substantial increase in field strength near the onset of the PCRS. The MPDL also adds support to the inverse relationship between reversal frequency and field strength and a possible ∼200-My cycle in paleomagnetic behavior relating to mantle convection.

The frequency of medical reversals in a cross-sectional analysis of high-impact oncology journals, 2009\u20132018

BackgroundIdentifying ineffective practices that have been used in oncology is important in reducing wasted resources and harm. We sought to examine the prevalence of practices that are being used but have been shown in RCTs to be ineffective (medical reversals) in published oncology studies.MethodsWe cross-sectionally analyzed studies published in three high-impact oncology medical journals (2009–2018). We abstracted data relating to the frequency and characterization of medical reversals.ResultsOf the 64 oncology reversals, medications (44%) represented the most common intervention type (39% were targeted). Fourteen (22%) were funded by pharmaceutical/industry only and 56% were funded by an organization other than pharmaceutical/industry. The median number of years that the practice had been in use prior to the reversal study was 9 years (range 1–50 years).ConclusionHere we show that oncology reversals most often involve the administration of medications, have been practiced for years, and are often identified through studies funded by non-industry organizations.

How does periodic polarity reversal affect the faradaic efficiency and electrode fouling during iron electrocoagulation?

Electrocoagulation (EC) is a promising electrochemical water treatment technology. However, a major challenge to sustaining effective long-term EC operation is controlling the precipitation of materials on the electrodes, commonly referred to as fouling. Periodically reversing electrode polarity has been suggested as an in-situ fouling mitigation strategy and is often implemented in EC field applications. However, the utility of this approach has not been investigated in detail. In this study, the effect of polarity reversal (PR) on the performance of EC using iron electrodes was examined under different water chemistry conditions and at a range of reversal frequencies. It was observed that the faradaic efficiency in PR-EC was always lower than that in the EC systems operated with a direct current (i.e., DC-EC). It was also observed that the faradaic efficiency progressively decreased as the current reversal frequency increased, with the faradaic efficiency dropping as low as 10% when the PR interval was 0.5 min. Results from fouling layer, chronopotentiometric, and cyclic voltammetric investigations indicated that the decrease in the faradaic efficiency was caused by (i) increased electrode fouling by iron precipitates and (ii) electrochemical side reactions at the electrode-electrolyte interface. The extent of these effects was dependent on the solution chemistry; oxyanions and sulfide were found to be particularly detrimental to the performance of PR-EC, causing severe electrode fouling while decreasing the faradaic efficiency. Fouling could be mitigated by increasing the solution convection rate, resulting in a shear on the electrode surface that removed iron and other electrochemically reactive species from the electrodes.

A Reversible Low Frequency Alternating Current Nerve Conduction Block Applied to Mammalian Autonomic Nerves.

Electrical stimulation can be used to modulate activity within the nervous system in one of two modes: (1) Activation, where activity is added to the neural signalling pathways, or (2) Block, where activity in the nerve is reduced or eliminated. In principle, electrical nerve conduction block has many attractive properties compared to pharmaceutical or surgical interventions. These include reversibility, localization, and tunability for nerve caliber and type. However, methods to effect electrical nerve block are relatively new. Some methods can have associated drawbacks, such as the need for large currents, the production of irreversible chemical byproducts, and onset responses. These can lead to irreversible nerve damage or undesirable neural responses. In the present study we describe a novel low frequency alternating current blocking waveform (LFACb) and measure its efficacy to reversibly block the bradycardic effect elicited by vagal stimulation in anaesthetised rat model. The waveform is a sinusoidal, zero mean(charge balanced), current waveform presented at 1 Hz to bipolar electrodes. Standard pulse stimulation was delivered through Pt-Black coated PtIr bipolar hook electrodes to evoke bradycardia. The conditioning LFAC waveform was presented either through a set of CorTec® bipolar cuff electrodes with Amplicoat® coated Pt contacts, or a second set of Pt Black coated PtIr hook electrodes. The conditioning electrodes were placed caudal to the pulse stimulation hook electrodes. Block of bradycardic effect was assessed by quantifying changes in heart rate during the stimulation stages of LFAC alone, LFAC-and-vagal, and vagal alone. The LFAC achieved and block using hook (N = 7) and cuff (N = 5) electrodes, respectively, at current levels less than 110 µAp (current to peak). The potential across the LFAC delivering electrodes were continuously monitored to verify that the blocking effect was immediately reversed upon discontinuing the LFAC. Thus, LFACb produced a high degree of nerve block at current levels comparable to pulse stimulation amplitudes to activate nerves, resulting in a measurable functional change of a biomarker in the mammalian nervous system.

Consistent and Contrasting Aspects of the Geomagnetic Field Across Epochs With Distinct Reversal Frequencies Revealed by Modeling the Kiaman Superchron

AbstractThis work presents an extensive directional paleomagnetic database of the Kiaman reversed superchron. It is composed of 1,459 paleomagnetic directions from igneous rocks corresponding to 91 data sets (or paleomagnetic poles). An almost constant behavior of more concentrated and circular distributions for latitudes higher than 10° was found, which contrasts strongly with predictions of the representative models for the past few million years. We searched for simplified and spatially covariant Giant Gaussian Process (GGP) models that best explain the directional distribution of the Kiaman database. We used the mean strength based on the mean of virtual dipole moment (VDM) results for the period drawn from the available databases. Among the tested models, the one that best explains the directional paleosecular variation of the Kiaman database is the covariant type. According to this model, the correlations between the Gaussian coefficients are valid for the last 10 Myr and the Kiaman superchron. The resulting GGP models have parameters similar to the 0–10 Ma models, which indicates that the relation between symmetric and antisymmetric families appears unchanged in the geological past. The relative variability of the Kiaman field, as inferred from the ratio from GGP models, is lower than for the past 10 Myr. Thus, as well as the paleointensity, seems to be a proxy that can be used for evaluating the geomagnetic development along the geological time.

Ecological risk assessment and long-term environmental pollution caused by obsolete undisposed organochlorine pesticides

Obsolete organochlorine pesticides (OSPs) are currently prohibited as persistent organic pollutants that contaminate the environment. If undisposed, they continue to pollute soil and water, to accumulate in the food chain and to harm plants, animals and the human body. The aim of the study was to assess water and soil pollution around the storehouses of undisposed, banned OSPs and their possible genotoxic effect. The storehouses in four villages near Almaty, Kazakhstan were investigated. Chemical analysis confirmed contamination of water and soil around storehouses with OSPs. The genotoxic effect of water and soil samples was evaluated using model objects: S.typhymurium, D.melanogaster, sheep lymphocytes cultures and human lymphocytes cultures. It was found that water and soil samples caused mutagenic effect in all model systems. They increased the frequency of revertants in Salmonella, the frequency of lethal mutations in Drosophila chromosomes, and the frequency of chromosome aberrations in cultures of human and sheep lymphocytes. Although a genotoxic effect was demonstrated for each of these models, various models showed different sensitivity to the effects of pesticides and they varied degree of response. The association between the total content of OCPs in soil and the level of mutations for different model systems was discovered.

The Effect of Thickness and Reversal Frequency of Seaweed Gracilaria sp Drying

Marketing of seaweed is still in the form of dried seaweed, but in fact the quality of the dried seaweedthat is sold by farmers has not met the standards required by the seaweed processing industry. One ofthe efforts that can be made to improve the quality of dried seaweed is by optimizing drying, namelyby adjusting the thickness and reversal frequency. Pile thickness of will determine the length of timedrying is carried out, while the frequency of reversal will determine the spread of heat that occurs inthe seaweed pile. The aim of this study was to determine the drying speed in seaweed Gracilaria spdrying and quality of dried sweaweed. The study was conducted with two treatments, namely pilethickness of 12, 16 and 20 cm and treatment of reversal frequency with an interval of 3 hours, 4 hoursand 5 hours. The parameters observed in this study were a decrease in water content, drying rate, andsensory test. The results showed that the drying of Gracilaria sp seaweed with a thicknessof 12 cm with a reversal frequency of each 3-4 hours is the best treatment in terms of color / brightnessand good texture with a drying rate of 0.462 kg H2O/kg solids hour.

Inverse Power Law based Inclusive Life Model for DC Polarity Reversal Stresses

In this paper, carefully designed experiments are reported, which indicate that the change in frequency of voltage polarity reversals results in a change in slope of v-t characteristics on the inverse power law. The power law parameters are shown to be systematic functions of frequency of polarity reversals. Based on these results, the authors propose a comprehensive inverse power law for DC polarity reversal stress application, in place of conventional inverse power law. The proposed modification is examined with experimental data of authors apart from that available in literature and found to be working well. The model provides the maximum frequency of a reversal for maximizing the life of power equipment which may pave the way for deciding on the maximum frequency of voltage reversals.

Earth's Magnetic Field Strength and the Cretaceous Normal Superchron: New Data From Costa Rica

AbstractConstraining the long‐term variability and average of the Earth's magnetic field strength is fundamental to understanding the characteristics and behavior of the geomagnetic field. Questions remain about the strength of the average field, and the relationship between strength and reversal frequency, due to the dispersion of data from key time intervals. Here, we focus on the Cretaceous Normal Superchron (CNS; 121‐84 Ma), during which there were no reversals. We present new intensity results from 41 submarine basaltic glass (SBG) sites collected on the Nicoya Peninsula and Murcièlago Islands, Costa Rica. New and revised40Ar/39Ar and biostratigraphic age constraints from previous studies indicate ages from 141 to 65 Ma. One site with an age of 135.1 ± 1.5 Ma (2σ) gave a reliable intensity result of 34 ± 8 µT (equivalent to a virtual axial dipole moment, VADM, value of 88 ± 20 ZAm2), three sites from 121 to 112 Ma, spanning the onset of the CNS, vary from 21 ± 1 to 34 ± 4 µT (53 ± 3 to 87 ± 10 ZAm2). These results from the CNS are all higher than the long‐term average of ∼42 ZAm2and data from Suhongtu, Mongolia (46–53 ZAm2) and are similar to the Troodos Ophiolite, Cyprus (81 ZAm2, reinterpreted in this study). Together with the reinterpreted data, the new Costa Rica results suggest that the strength of the geomagnetic field was approximately the same both before and after the onset of the CNS. Therefore, the data do not support a strict correlation between polarity interval length and the strength of the magnetic field.

Mitigating Electrode Fouling in Electrocoagulation by Means of Polarity Reversal: The Effects of Electrode Type, Current Density, and Polarity Reversal Frequency

One of the biggest issues in electrocoagulation (EC) water treatment processes is electrode fouling, which can cause decreased coagulant production, increased ohmic resistance and energy consumption, and reduced contaminant removal efficiency, among other operational problems. While it has been suggested that switching the current direction intermittently (i.e., polarity reversal, PR) can help mitigate electrode fouling, conflicting results about the utility of this approach have been reported in the literature. The objective of this study was to systematically investigate the effects of PR frequency and current density on the performance of Fe-EC and Al-EC. It was found that operating Fe-EC under the PR mode reduced neither electrode fouling nor energy consumption. Notably, the Faradaic efficiency (ϕ) in Fe-EC decreased with increasing PR frequency; ϕ was as low as 10% when a PR frequency of 0.5 minutes was employed. Unlike Fe-EC, operating Al-EC under the PR mode resulted in high coagulant production efficiencies, reduced energy consumption, and diminished electrode fouling. In addition to comparing PR-EC and DC-EC, a novel strategy to minimize electrode fouling was investigated. This strategy involved operating Fe DC-EC and Al DC-EC with a Ti-IrO2 cathode, whose fouling by Ca- and Mg-containing minerals could be readily avoided by periodically switching the current direction.

AptaNet as a deep learning approach for aptamer\u2013protein interaction prediction

Aptamers are short oligonucleotides (DNA/RNA) or peptide molecules that can selectively bind to their specific targets with high specificity and affinity. As a powerful new class of amino acid ligands, aptamers have high potentials in biosensing, therapeutic, and diagnostic fields. Here, we present AptaNet—a new deep neural network—to predict the aptamer–protein interaction pairs by integrating features derived from both aptamers and the target proteins. Aptamers were encoded by using two different strategies, including k-mer and reverse complement k-mer frequency. Amino acid composition (AAC) and pseudo amino acid composition (PseAAC) were applied to represent target information using 24 physicochemical and conformational properties of the proteins. To handle the imbalance problem in the data, we applied a neighborhood cleaning algorithm. The predictor was constructed based on a deep neural network, and optimal features were selected using the random forest algorithm. As a result, 99.79% accuracy was achieved for the training dataset, and 91.38% accuracy was obtained for the testing dataset. AptaNet achieved high performance on our constructed aptamer-protein benchmark dataset. The results indicate that AptaNet can help identify novel aptamer–protein interacting pairs and build more-efficient insights into the relationship between aptamers and proteins. Our benchmark dataset and the source codes for AptaNet are available in: https://github.com/nedaemami/AptaNet.

High-Performance Ti/IrO2–RhOx–Ta2O5Electrodes for Polarity Reversal Applications

Electrode polarity reversal has been widely employed to inhibit membrane fouling and induce scale detachment during electrodialysis and electrochemical precipitation, respectively. However, frequent polarity reversal shortens the lifetime of traditional dimensionally stable anodes. In this study, a novel titanium electrode that employed a ternary iridium, tantalum, and rhodium oxide mixture (IrO₂–RhOx–Ta₂O₅) as an active electrocatalyst film was investigated for polarity reversal applications. It was found that the Ti/IrO₂–RhOx–Ta₂O₅ electrode with an Ir/Rh/Ta molar ratio of 3:3:4 had a service lifetime of 1030 h in a 20 g L–¹ Na₂SO₄ solution at a current density of 2000 A m–² and a polarity reversal frequency of 12 h–¹. In contrast, a Ti/IrO₂–Ta₂O₅ electrode with an Ir/Ta molar ratio of 6:4 under the same conditions exhibited a service lifetime of only 275 h. Physicochemical characterization revealed that the IrO₂–RhOx–Ta₂O₅ film has a compact microstructure, solid solution characteristics, and contains both Rh³⁺ and Rh⁴⁺ which contributes to the stability during polarity reversal. Moreover, the Ti/IrO₂–RhOx–Ta₂O₅ electrode showed better chlorine evolution performance than the Ti/IrO₂–Ta₂O₅ electrode.

Late Ediacaran magnetic field hyperactivity: Quantifying the reversal frequency in the Zigan Formation, Southern Urals, Russia

The behavior and strength of the Late Ediacaran-Early Cambrian magnetic field may provide a unique background for unravelling controversial plate reconstructions, the nature of the inner core and even biological evolution. Recent studies suggest that the Ediacaran dipole field strength was extremely low and that the magnetic field was in a hyperactive reversing state (>4–6 R/Ma) well into the Cambrian. Data supporting hyperactive reversals are derived from numerous studies of sedimentary successions in Baltica including the 547 Ma Zigan formation in the Urals. Although some of the younger, Cambrian-age, sedimentary sequences have robust age control, estimates of reversal frequency in the Zigan Formation was based on average sedimentation rates. In this study, we returned to a thick (~75 m) section of the Zigan and sampled for both magnetostratigraphic and magnetic susceptibility at a finer scale (~20 cm). The magnetic susceptibility data were used to evaluate orbitally-forced frequency signals that my provide a higher resolution estimate of reversal frequency. In particular, the stable long eccentricity signal of 405 Kyr was recognized in a frequency analysis of magnetic susceptibility. The identification of this periodic signal allowed us to refine the estimate for reversal frequency in the section to 20 R/Ma. Although slightly smaller than an original estimate of 25 R/Ma, this rate is well above the Phanerozoic background reversal rate and 3–5 times higher than the cut-off for hyperactivity. Our study thus confirms the hyperactive reversal interval from at least the latest Ediacaran until sometime in Epoch 3 of the Cambrian.

The Snail transcription factor CES-1 regulates glutamatergic behavior in C. elegans.

Regulation of AMPA-type glutamate receptor (AMPAR) expression and function alters synaptic strength and is a major mechanism underlying synaptic plasticity. Although transcription is required for some forms of synaptic plasticity, the transcription factors that regulate AMPA receptor expression and signaling are incompletely understood. Here, we identify the Snail family transcription factor ces-1 in an RNAi screen for conserved transcription factors that regulate glutamatergic behavior in C. elegans. ces-1 was originally discovered as a selective cell death regulator of neuro-secretory motor neuron (NSM) and I2 interneuron sister cells in C. elegans, and has almost exclusively been studied in the NSM cell lineage. We found that ces-1 loss-of-function mutants have defects in two glutamatergic behaviors dependent on the C. elegans AMPA receptor GLR-1, the mechanosensory nose-touch response and spontaneous locomotion reversals. In contrast, ces-1 gain-of-function mutants exhibit increased spontaneous reversals, and these are dependent on glr-1 consistent with these genes acting in the same pathway. ces-1 mutants have wild type cholinergic neuromuscular junction function, suggesting that they do not have a general defect in synaptic transmission or muscle function. The effect of ces-1 mutation on glutamatergic behaviors is not due to ectopic cell death of ASH sensory neurons or GLR-1-expressing neurons that mediate one or both of these behaviors, nor due to an indirect effect on NSM sister cell deaths. Rescue experiments suggest that ces-1 may act, in part, in GLR-1-expressing neurons to regulate glutamatergic behaviors. Interestingly, ces-1 mutants suppress the increased reversal frequencies stimulated by a constitutively-active form of GLR-1. However, expression of glr-1 mRNA or GFP-tagged GLR-1 was not decreased in ces-1 mutants suggesting that ces-1 likely promotes GLR-1 function. This study identifies a novel role for ces-1 in regulating glutamatergic behavior that appears to be independent of its canonical role in regulating cell death in the NSM cell lineage.

Determination of Eddy-Current and Hysteresis Losses in the Magnetic Circuits of Electrical Machines

We consider the problem of separation of the total losses in the electric steel of a magnetic circuit into two components: the losses caused by hysteresis and the losses caused by eddy currents. The solution of this technical problem would enable us to guarantee the possibility of efficient design and construction electric machines with magnetic circuits characterized by low magnetic losses. We deduce computational formulas for the hysteresis and eddy-current components of losses, which contain the levels of total losses measured in the open-circuit tests for two different frequencies of magnetization reversal and the ratio of these frequencies. It is shown that the optimal ratio of the frequencies of magnetization reversal is equal to 1.2. We also present the plots of dependences and the expressions aimed at finding the exponent of dependence of the frequency of magnetization reversal on the measured open-circuit losses and the values of frequency.

High elevation increases the risk of Y chromosome loss in Alpine skink populations with sex reversal.

The view that has genotypic sex determination and environmental sex determination as mutually exclusive states in fishes and reptiles has been contradicted by the discovery that chromosomal sex and environmental influences can co-exist within the same species, hinting at a continuum of intermediate states. Systems where genes and the environment interact to determine sex present the opportunity for sex reversal to occur, where the phenotypic sex is the opposite of that predicted by their sex chromosome complement. The skink Bassiana duperreyi has XX/XY sex chromosomes with sex reversal of the XX genotype to a male phenotype, in laboratory experiments, and in field nests, in response to exposure to cold incubation temperatures. Here we studied the frequency of sex reversal in adult populations of B. duperreyi in response to climatic variation, using elevation as a surrogate for environmental temperatures. We demonstrate sex reversal in the wild for the first time in adults of a reptile species with XX/XY sex determination. The highest frequency of sex reversal occurred at the highest coolest elevation location, Mt Ginini (18.46%) and decreased in frequency to zero with decreasing elevation. We model the impact of this under Fisher's frequency-dependent selection to show that, at the highest elevations, populations risk the loss of the Y chromosome and a transition to temperature-dependent sex determination. This study contributes to our understanding of the risks of extinction from climate change in species subject to sex reversal by temperature, and will provide focus for future research to test on-the-ground management strategies to mitigate the effects of climate in local populations.

Mathematical Modelling of Contact-Dependent Motility Coordination in Myxococcus Xanthus

Myxococcs xanthus exhibits “social” behaviors, such as cooperative feeding and fruiting-body formation, through intercellular communication and coordination. A particular intriguing intercellular coordination lies in coordination of motility between cells with physical contacts. Specifically, M. xanthus cells glide on substrate with periodic reversals, and physical contacts with opposite-moving colony mates regulate their reversal frequency. This contact-dependent motility coordination is known to be necessary for generating intriguing population patterns, such as rippling waves.

Geomagnetic polarity during the early Silurian: The first magnetostratigraphy of the Llandovery

Magnetostratigraphic studies in the Silurian are absent, and what is understood about the geomagnetic polarity during this time is based on polarity bias-type data from palaeopole-type studies. We provide the first composite magnetic polarity record through the Lower Silurian (Llandovery) from the magnetostratigraphy of six sections. These are integrated with graptolite biostratigraphy and some carbon isotope chemostratigraphy. The palaeomagnetic signal is carried by both haematite and magnetite, with haematite dominating in red-coloured mudstones and mostly magnetite in non-red lithologies. The influence of possible tectonic disruption of the fabric is assessed using anisotropy of magnetic susceptibility. Only the most thermally mature section at Backside Beck shows the imprint of initial tectonic fabric formation. The Llandovery is divided into 6 major normal-reverse-polarity chron couplets (referred to as LL1 to LL6). An additional longer, exclusively normal polarity interval (referred to as WE1n), beginning in Telychian Stage slice Te3, runs into the lower Sheinwoodian. Within these five polarity couplets there are 10 further submagnetozones, and 10 tentative submagnetozones. Average reversal frequency (including the tentative submagnetozones) was ca. 3.0 Myr−1 in the Early Silurian, which is probably an underestimate, due to insufficient sampling density in some parts of the Rhuddanian and Aeronian. This reversal frequency is similar to that in the late Cenozoic, indicating the future potential utility of magnetostratigraphy for high-resolution correlation and dating in the Early Silurian.

Asymmetric random walks reveal that the chemotaxis network modulates flagellar rotational bias in Helicobacter pylori.

The canonical chemotaxis network modulates the bias for a particular direction of rotation in the bacterial flagellar motor to help the cell migrate toward favorable chemical environments. How the chemotaxis network in Helicobacter pylori modulates flagellar functions is unknown, which limits our understanding of chemotaxis in this species. Here, we determined that H. pylori swim faster (slower) whenever their flagella rotate counterclockwise (clockwise) by analyzing their hydrodynamic interactions with bounding surfaces. This asymmetry in swimming helped quantify the rotational bias. Upon exposure to a chemo-attractant, the bias decreased and the cells tended to swim exclusively in the faster mode. In the absence of a key chemotaxis protein, CheY, the bias was zero. The relationship between the reversal frequency and the rotational bias was unimodal. Thus, H. pylori's chemotaxis network appears to modulate the probability of clockwise rotation in otherwise counterclockwise-rotating flagella, similar to the canonical network.

A geomagnetic polarity stratigraphy for the Middle and Upper Ordovician

Magnetostratigraphic studies of the Ordovician provide evidence for the nature of core-mantle boundary interactions, and provide means for dating and correlation across differing environmental regimes. We provide new magnetostratigraphic data from the Middle and Upper Ordovician, compiling this into a polarity chronostratigraphic scale for the Dapingian to Hirnantian interval. The new data are derived from the Backside Beck and Cheney Longville sections in Britain, the Mójcza section in Poland and two cores from Poland and Lithuania. The chronology is provided by existing biostratigraphy, principally based on chitinozoans and conodonts for the Ordovician. Correlations between sections are supported by carbon isotope stratigraphy linked to Baltic isotopic zonations, along with lithological and local magnetic susceptibility correlations in Polish cores. The palaeomagnetic signal is carried by both haematite and magnetite, with haematite dominating in red-coloured lithologies (marls and limestones) and magnetite in non-red mudstones and limestones. A positive reversal test (class C) in the Cheney Longville section and positive fold tests in the Backside Beck section provide validation of the isolation of a primary palaeomagnetic signal. Palaeomagnetic directions from cores were re-oriented using Kiaman-age and Brunhes overprints. These new datasets in combination with existing Middle Ordovician data provides a near-complete magnetic polarity chronostratigraphic scale through the Middle and Upper Ordovician. Brief normal-polarity magnetozones extend well into the later parts of what has been considered the Moyero Superchron, which started in the late Tremadocian. Reversal frequencies for the mid and late Ordovician are 1.7 and 1.5 Myr−1 respectively, although that for the late Ordovician may be an underestimate.