Schools should be safe places where children and young people are hosted during their training years to develop their abilities and skills and to receive an education that makes them prepared to become the future of the nations where they live. Even though these aspects are of paramount importance and widespread recognized, the same importance does not seem to be equally ensured to school facilities. Educational institutes, indeed, are often old and realized without recent safety Standards, becoming consequently non-resilient, nor robust structures towards multiple natural hazards. This aspect concerns lots of countries worldwide, without making distinction among their richness level.In this paper empirical models for the prediction of damage and retrofit costs expected after earthquakes are presented. These probabilistic models relate seismic intensity to expected damage and economic losses, through the definition of continuous indexes, and are based on data collected after a recent earthquake occurred in Central Italy. Empirical data, required to define the probabilistic models, have been obtained by combining information coming from shaking maps, provided by the National Institute for Geophysics and Volcanology (INGV), information on the building properties (e.g. locations, dimensions, construction typology), provided by the Ministry of Education, and data about the damage suffered by constructions and funding for retrofit actions including damage repairing and seismic upgrading, provided by the Reconstruction Office. Proposed models provide the opportunity to directly derive fragility curves, to make it possible the use of the research outcomes in risk frameworks based on a discrete description of the damages and losses.Model parameters have been calibrated for the considered set of available data, but the methodology is general and can be also applied to different contexts, given data are available. Finally, the proposed models have been used to simulate the post-earthquake damage and losses scenario following a seismic event. A proposal for the analyses of probabilistic outputs have been developed to provide information useful to decision making purpose.