Autobiographical Memory Retrieval Research Articles

How the body remembers: Examining the default mode and sensorimotor networks during moral injury autobiographical memory retrieval in PTSD

Neural representations of sensory percepts and motor responses constitute key elements of autobiographical memory. However, these representations may remain as unintegrated sensory and motor fragments in traumatic memory, thus contributing toward re-experiencing and reliving symptoms in trauma-related conditions such as post-traumatic stress disorder (PTSD). Here, we investigated the sensorimotor network (SMN) and posterior default mode network (pDMN) using a group independent component analysis (ICA) by examining their functional connectivity during a script-driven memory retrieval paradigm of (potentially) morally injurious events in individuals with PTSD and healthy controls. Moral injury (MI), where an individual acts or fails to act in a morally aligned manner, is examined given its inherent ties to disrupted motor planning and thus sensorimotor mechanisms. Our findings revealed significant differences in functional network connectivity across the SMN and pDMN during MI retrieval in participants with PTSD (n = 65) as compared to healthy controls (n = 25). No such significant group-wise differences emerged during retrieval of a neutral memory. PTSD-related alterations included hyperconnectivity between the SMN and pDMN, enhanced within-network connectivity of the SMN with premotor areas, and increased recruitment of the supramarginal gyrus into both the SMN and the pDMN during MI retrieval. In parallel with these neuroimaging findings, a positive correlation was found between PTSD severity and subjective re-experiencing intensity ratings after MI retrieval. These results suggest a neural basis for traumatic re-experiencing, where reliving and/or re-enacting a past morally injurious event in the form of sensory and motor fragments occurs in place of retrieving a complete, past-contextualized narrative as put forth by Brewin and colleagues (1996) and Conway and Pleydell-Pearce (2000). These findings have implications for bottom-up treatments targeting directly the sensory and motoric elements of traumatic experiences.

Accounting for the strangeness, infrequency, and suddenness of déjà vu.

Barzykowski and Moulin argue that déjà vu is a natural product of autobiographical memory retrieval. Their proposal fails to account for three salient properties of déjà vu experiences: Their strangeness, their infrequency, and their characteristically sudden onset. Accounting for these properties is necessary for proper integration of déjà vu into autobiographical memory research.

Gaze direction as a facial cue of memory retrieval state.

Gaze direction is a powerful social cue that indicates the direction of attention and can be used to decode others' mental states. When an individual looks at an external object, inferring where their attention is focused from their gaze direction is easy. But when people are immersed in memories, their attention is oriented towards their inner world. Is there any specific gaze direction in this situation, and if so, which one? While trying to remember, a common behavior is gaze aversion, which has mostly been reported as an upward-directed gaze. Our primary aim was to evaluate whether gaze direction plays a role in the inference of the orientation of attention-i.e., external vs. internal-in particular, whether an upward direction is considered as an indicator of attention towards the internal world. Our secondary objective was to explore whether different gaze directions are consistently attributed to different types of internal mental states and, more specifically, memory states (autobiographical or semantic memory retrieval, or working memory). Gaze aversion is assumed to play a role in perceptual decoupling, which is supposed to support internal attention. We therefore also tested whether internal attention was associated with high gaze eccentricity because the mismatch between head and eye direction alters visual acuity. We conducted two large-sample (160-163 participants) online experiments. Participants were asked to choose which mental state-among different internal and external attentional states-they would attribute to faces with gazes oriented in different directions. Participants significantly associated internal attention with an upward-averted gaze across experiments, while external attention was mostly associated with a gaze remaining on the horizontal axis. This shows that gaze direction is robustly used by observers to infer others' mental states. Unexpectedly, internal attentional states were not more associated with gaze eccentricity at high (30°) than low (10°) eccentricity and we found that autobiographical memory retrieval, but not the other memory states, was highly associated with 10° downward gaze. This reveals the possible existence of different types of gaze aversion for different types of memories and opens new perspectives.

Roles of Trait Mindfulness and Working Memory Capacity in Life Goal and Autobiographical Memory Specificities

Low life goal and autobiographical memory specificities are associated with negative psychological symptoms. Short-term mindfulness trainings can increase life goal and autobiographical memory specificities. The present study extends the literature by investigating whether trait mindfulness is associated with life goal and autobiographical memory specificities. Additionally, because mindfulness trainings improve working memory capacity, which is associated with future episodic specificity and autobiographical memory retrieval, a second aim of this study was to examine whether working memory capacity moderates the relationship between trait mindfulness and life goal and autobiographical memory specificities. 96 participants completed the Freiburg Mindfulness Inventory, Automated Operational Span task, minimal instructions Autobiographical Memory Test, and Measure to Elicit Positive Future Goals and Plans. A multiple regression analysis revealed that the presence aspect of trait mindfulness and the interaction of the acceptance aspect of trait mindfulness and working memory capacity were predictive for goal specificity. A follow-up simple slope analysis revealed that high acceptance aspect of mindfulness was associated with low goal specificity in participants with a high working memory capacity. However, this association was not present in participants with medium and low working memory capacity. Neither trait mindfulness nor working memory capacity were associated with autobiographical memory specificity. Findings suggest that present-moment awareness enables one to focus on accessing event-specific knowledge, and that an accepting attitude alone cannot help people with high working memory capacity to make more concrete and specific future plans. The lack of association between trait mindfulness and autobiographical memory specificity might be attributed to low specific memories found in this study.

Negative body image and avoidant retrieval of body-related autobiographical memories

ABSTRACT People with a negative body image may be more likely to recall negative memories of their body, but also be motivated to avoid retrieving specific memories to prevent triggering aversive emotions (e.g., disgust). Such inclination to retain at a global level of memory recall may hamper the correction of their negative body image. In previous research using Autobiographical Memory Tests (AMTs) with minimal instructions, we failed to find an overgeneral memory bias specific to individuals with a negative body image but observed low specificity overall in response to body cue words. In the present study (N = 153), we included the traditional AMT next to a minimal instructions AMT and explored the idea that sensory reliving may be relevant to avoidance by assessing sensory reliving ratings next to memory specificity. A negative body image was associated with more negative body memories. In both AMTs, the findings failed to support our prediction that a more negative body image would be associated with lower specificity or sensory reliving. The findings are consistent with the view that autobiographical memories might be an important factor in defining one’s body image, yet cast doubt on the relevance of avoidant retrieval of body-related memories in non-clinical samples.

Odor associated memories are not necessarily highly emotional

Laboratory and clinical studies have shown that odors tend to evoke highly emotional autobiographical memories that frequently come from an early period in life. One potential explanation for this effect is that all memories associated with odors are particularly emotional, while another potential explanation is that the presence of an (emotional) odor during retrieval leads to the participants' impression that the retrieved memory is particularly emotional. To this point, nearly all research on odor evoked autobiographical memories has relied on the presence of an odor to cue the memory, a procedure that does not allow one to distinguish whether the emotionality of the memories is due to the memory itself or the presence of the current cue. In contrast, in the current studies, no stimuli were presented during the retrieval of autobiographical memories. Instead, we asked people to report on memories specifically associated with the five traditional different senses or asked for information about autobiographical memories evoked throughout the day and assessed the role of the senses in those experienced memories. Across the three studies, using slightly different methodologies, we found that odor associated autobiographical memories are not more emotional or older than memories (mainly) associated with other modalities. Our results carefully put into question the notion that odor associated autobiographical memories are more emotional than autobiographical memories mostly associated with other modalities. Since the difference between the presented and previous studies lies in a different situation at AM retrieval, these results present evidence towards retrieval-based explanations.

Similarity in activity and laterality patterns in the angular gyrus during autobiographical memory retrieval and self-referential processing.

Long-term memory is arguably one of the key cognitive functions. At the neural level, the lateral parietal cortex and the angular gyrus, particularly in the left hemisphere, exhibit strong activations during autobiographical and episodic memory retrieval. In a separate sub-field, left-lateralized activations of the angular gyrus are also found during self-referential processing, defined as higher activity when a trait term is judged by participants as being related to them vs. related to someone else. The question is whether episodic/autobiographical memory retrieval and self-referential processing effects are related. In the present study, thirty participants participated in the fMRI study with two separate experiments: autobiographical memory retrieval (Experiment 1) and self-referential processing (Experiment 2). In a series of analyses, including the most critical spatial correlation analysis between experiments, we found neural similarity between autobiographical memory retrieval and self-referential processing. Given that self-referential processing was identified in a selective way, the most plausible interpretation of our findings is that self-referential processing might partly explain the activation of the left angular gyrus during autobiographical memory retrieval. Our results are in line with the seminal view of Endel Tulving that the sense of self is a fundamental attribute of long-term memory recollection. However, it should be emphasized that: a) our results do not imply that the left angular gyrus is not involved in the retrieval of episodic memory details; and b) given that our experiment included an autobiographical memory task, generalization of our results to the episodic memory laboratory tasks has yet to be tested.

How shifting visual perspective during autobiographical memory retrieval influences emotion: A change in retrieval orientation

Visual perspective during autobiographical memory (AM) retrieval influences how people remember the emotional aspects of memories. Prior research in emotion regulation has also shown that shifting from an own eyes to an observer-like perspective is an efficient way of regulating the affect elicited by emotional AMs. However, the impact of shifting visual perspective is also dependent on the nature of the emotion associated with the event. The current review synthesizes behavioral and functional neuroimaging findings from the event memory and emotion regulation literature that examine how adopting particular visual perspectives and actively shifting across them during retrieval alters emotional experience, by primarily focusing on emotional intensity. We review current theories explaining why shifts in perspectives may or may not change the emotional characteristics of memories, then propose a new theory, suggesting that the own eyes and observer-like perspectives are two different retrieval orientations supported by differential neural activations that lead episodic details to be reconstructed in specific ways.

The Effects of an Online Mindfulness Intervention on Emotion Regulation upon Autobiographical Memory Retrieval in Depression Remission: a Pilot Randomized Controlled Trial

ObjectivesMaladaptive emotional processing of autobiographical memories is a key feature of depression that may persist during depressive remission. The primary objective of the present study was to assess the effects of an online mindfulness-based stress reduction (MBSR) intervention on emotion regulation upon everyday autobiographical memory retrieval in individuals with remitted depression.MethodsWe conducted a pilot randomized controlled trial in which students (76.4% female; mean age 22.26) with remitted depression were allocated to an 8-week online MBSR program (n = 28) or a waitlist-control condition (n = 27). The primary outcome was self-reported employment of five emotion regulation strategies and non-reactivity upon everyday retrieval of involuntary and voluntary autobiographical memories recorded in a memory diary and was measured at baseline and approximately 11 weeks postrandomization. Intention-to-treat (ITT) and per-protocol (PP) analyses were performed.ResultsParticipants in the MBSR condition showed increases in non-reactivity irrespective of memory retrieval mode (ITT: d = 1.04, p = .010; PP: d = 1.58, p = .015), and increased use of cognitive reappraisal in response to involuntary memories (ITT: d = 0.41, p = .051; PP: d = − 0.62, p = .032) compared to the waitlist-control condition. Analyses of secondary outcomes showed additional effects for trait mindfulness and trait cognitive reappraisal, as well as depression symptoms and trait thought suppression.ConclusionThese results provide preliminary evidence for the utility of using an online mindfulness program for improving emotion regulation upon autobiographical memory retrieval during depression remission.Retrospective Trial RegistrationClinicalTrials.gov, NCT05121116.

Are involuntary autobiographical memory and déjà vu natural products of memory retrieval?

Involuntary autobiographical memories (IAMs) and déjà vu are phenomena that occur spontaneously in daily life. IAMs are recollections of the personal past, whereas déjà vu is defined as an experience in which the person feels familiarity at the same time as knowing that the familiarity is false. We present and discuss the idea that both IAMs and déjà vu can be explained as natural phenomena resulting from memory processing and, importantly, are both based on the same memory retrieval processes. Briefly, we hypothesise that both can be described as "involuntary" or spontaneous cognitions, where IAMs deliver content and déjà vu delivers only the feeling of retrieval. We map out the similarities and differences between the two, making a theoretical and neuroscientific account for their integration into models of memory retrieval and how the autobiographical memory literature can explain these quirks of daily life and unusual but meaningful phenomena. We explain the emergence of the déjà vu phenomenon by relating it to well-known mechanisms of autobiographical memory retrieval, concluding that IAMs and déjà vu lie on a continuum.

The effect of positive autobiographical memory retrieval on decision-making under risk: A computational model-based analysis.

Psychiatric disorders such as depressive and anxiety disorders are associated with altered decision-making under risk. Recent advances in neuroeconomics and computational psychiatry have further discomposed risk-based decision-making into distinct cognitive computational constructs and showed that there may be disorder-specific alterations in these constructs. As a result, it has been suggested these cognitive computational constructs may serve as useful behavioral biomarkers for these disorders. However, to date, little is known about what psychological or behavioral interventions can help to reverse and manage the altered cognitive computational constructs underlying risk-based decision-making. In the present study, we set out to investigate whether recalling positive autobiographical memories may affect risk-based decision-making in healthy volunteers using a description-based task. Specifically, based on theories of behavioral economics, we dissected risk preference into two cognitive computational constructs, utility sensitivity and probability weighting. We found that compared to recalling neutral memories, retrieving positive autobiographical memories increased utility sensitivity (Cohen's d = 0.447), indicating reduced risk aversion. Meanwhile, we also tested the influence of memory retrieval on probability weighting, the effect, however, was unreliable and requires further in-depth investigation. Of clinical relevance, the change in risk aversion after recalling positive memories was in the opposite direction compared to those reported in psychiatric disorders. These results argue for the potential therapeutic effect of positive autobiographical memory retrieval for the amendment of altered risk-based decision-making in psychiatric disorders.

EEG evidence that morally relevant autobiographical memories can be suppressed

Remembering unpleasant events can trigger negative feelings. Fortunately, research indicates that unwanted retrieval can be suppressed to prevent memories from intruding into awareness, improving our mental state. The current scientific understanding of retrieval suppression, however, is based mostly on simpler memories, such as associations between words or pictures, which may not reflect how people control unpleasant memory intrusions in everyday life. Here, we investigated the neural and behavioural dynamics of suppressing personal and emotional autobiographical memories using a modified version of the Think/No-Think task. We asked participants to suppress memories of their own past immoral actions, which were hypothesised to be both highly intrusive and motivating to suppress. We report novel evidence from behavioural, ERP, and EEG oscillation measures that autobiographical memory retrieval can be suppressed and suggest that autobiographical suppression recruits similar neurocognitive mechanisms as suppression of simple laboratory associations. Suppression did fail sometimes, and EEG oscillations indicated that such memory intrusions occurred from lapses in sustained control. Importantly, however, participants improved at limiting intrusions with repeated practice. Furthermore, both behavioural and EEG evidence indicated that intentional suppression may be more difficult for memories of our morally wrong actions than memories of our morally right actions. The findings elucidate the neurocognitive correlates of autobiographical retrieval suppression and have implications for theories of morally motivated memory control.

Sad reflections of happy times: depression vulnerability and experiences of sadness and happiness upon retrieval of positive autobiographical memories

ABSTRACT Instructed retrieval of positive autobiographical memories typically improves mood for healthy individuals, but not always for depressed individuals. No mood improvement may occur when depressed individuals retrieve positive memories that are self-incongruent, or when they ruminate upon positive memory retrieval. Mindfulness is associated with lower self-incongruency and rumination. The present study examined whether recurrent depression predicted emotional experience upon involuntary and voluntary retrieval of positive memories, and whether recurrent depression and trait mindfulness were associated with emotional experience upon positive memory retrieval through state rumination and self-incongruency. Recurrently and never-depressed individuals completed measures of depression, trait mindfulness, and a diary for reporting on everyday positive memories. Recurrently depressed individuals reported diminished happiness upon retrieving involuntary and voluntary positive memories compared to never-depressed individuals; and greater sadness upon involuntary positive memory retrieval, independent of current depression. Recurrent depression was associated with diminished happiness upon involuntary memory retrieval and greater sadness upon involuntary and voluntary positive memory retrieval, through state brooding, self-incongruency, or both. Higher trait mindfulness was associated with lower sadness upon involuntary and voluntary positive memory retrieval through state brooding and reflection. These findings highlight potential mechanisms in the relationship between depression vulnerability and emotional processing of positive autobiographical memories.

A Role for the Anterior Hippocampus in Autobiographical Memory Construction Regardless of Temporal Distance.

Mounting evidence suggests distinct functional contributions of the anterior and posterior hippocampus to autobiographical memory retrieval, but how these subregions function under different retrieval demands as memories age is not yet understood. Specifically, autobiographical memory retrieval is not a homogeneous process; rather, it is thought to consist of the following multiple stages: an early stage of memory construction and a later stage of detailed elaboration, which may differently engage the hippocampus over time. In the present study, we analyzed data from 40 participants (23 female/17 male) who constructed and overtly elaborated on recent and remote memories in response to picture cues in the fMRI scanner. We previously reported a temporal gradient in the posterior hippocampus during the elaboration period of autobiographical retrieval, with posterior hippocampal activation observed for recent but not remote time points. Here, we consider the previously unanalyzed construction stage of retrieval, where participants searched for and selected a memory. We found no evidence of a temporal gradient during memory construction, instead observing strong anterior hippocampus activity regardless of memory remoteness. Our findings suggest a unique contribution of the anterior hippocampus to the construction process of autobiographical retrieval over time. These findings highlight that retrieval processes, which have yet to be integrated with current models of systems consolidation, offer novel insights into hippocampal subregion function over time.SIGNIFICANCE STATEMENTHippocampal contributions to autobiographical memory retrieval may depend on several distinct factors including memory age and the retrieval process engaged. We previously found that the contribution of the posterior hippocampus to detailed elaborative retrieval diminishes as memories age, with no reliable activation of the anterior hippocampus over time. Here, we report that consideration of the earlier "construction" period of retrieval, where participants search for and retrieve general aspects of the memory, yielded significant anterior hippocampus activation regardless of memory age. These results provide evidence for a unique contribution of the anterior hippocampus to the constructive process of autobiographical retrieval over time and suggest that component processes of retrieval should be integrated into models of systems consolidation.

Olfactory imagery as a retrieval method for autobiographical memories

IntroductionThe retrieval of autobiographical memories is influenced by several factors, such as sensory modality and the emotional salience of memory cues. This study aimed at investigating the interaction between sensory modalities (olfaction, vision) and emotional dimensions (valence, arousal) of imagery cues, on the frequency, quality, and age distribution of the autobiographical memories (AMs) elicited.MethodA total of 296 females (aged between 18 and 35 years) received one out of eight brief instructions for olfactory or visual imagery. The participants were asked to create a mental image with either high arousal/positive valence, high arousal/negative valence, low arousal/positive valence, or low arousal/negative valence (e.g., ‘imagine an unpleasant and arousing odor/scene’); no specific stimulus was mentioned in the instruction.ResultsThe approach used elicited imagery with autobiographical content in the majority of participants (78%). In terms of frequency, odor imagery, compared to visual imagery, turned out to be more effective at retrieving either unpleasant memories associated with experiences in adulthood, or pleasant childhood memories. In terms of quality, the imagery was rated as less vivid in the olfactory compared to the visual condition (irrespective of valence and arousal of the imagery instruction). Visual imagery was associated with the experience of more diverse emotions (happiness, sadness, anxiety, anger) than odor imagery, which was related primarily with disgust and happiness.ConclusionOur findings indicate that nonspecific imagery induction is a useful approach in accessing AM.ImplicationThis approach presents promising clinical applications, such as in working with autobiographical memory narratives in psychotherapy.

Comparing neural activity during autobiographical memory retrieval between younger and older adults: An ALE meta-analysis

Aging changes autobiographical memory (AM), yet the neural correlates of these changes are poorly understood, likely due to methodological variability across studies. We conducted a quantitative meta-analysis using activation likelihood estimation (GingerALE 3.0.2) to identify regions AM retrieval engaged in younger and older adults across 45 studies (Nyounger = 24 studies, 357 participants, 349 foci; Nolder = 21 studies, 299 participants, 356 foci), considering methodological differences in cueing AMs (i.e., using generic vs. specific/personalized cues). Both age-groups commonly engaged a left-lateralized pattern of brain activity that included the hippocampus, retrosplenial/posterior cingulate cortex, and angular gyrus. Younger adults showed enhanced right posterior cingulate cortical activity, while older adults presented with bilateral activity in the hippocampus, and enhanced activity in left middle temporal gyrus, precuneus, and retrosplenial cortex. Exploratory analyses indicated that age-related commonalties and differences in brain activity depended on the method of AM cuing. These findings suggest that key regions of AM retrieval are preserved in older age, yet subtle changes exist, especially depending on how AMs are cued.

Posterior cingulate cortex reveals an expression profile of resilience in cognitively intact elders.

The posterior cingulate cortex, a key hub of the default mode network, underlies autobiographical memory retrieval and displays hypometabolic changes early in Alzheimer disease. To obtain an unbiased understanding of the molecular pathobiology of the aged posterior cingulate cortex, we performed RNA sequencing (RNA-seq) on tissue obtained from 26 participants of the Rush Religious Orders Study (11 males/15 females; aged 76–96 years) with a pre-mortem clinical diagnosis of no cognitive impairment and post-mortem neurofibrillary tangle Braak Stages I/II, III, and IV. Transcriptomic data were gathered using next-generation sequencing of RNA extracted from posterior cingulate cortex generating an average of 60 million paired reads per subject. Normalized expression of RNA-seq data was calculated using a global gene annotation and a microRNA profile. Differential expression (DESeq2, edgeR) using Braak staging as the comparison structure isolated genes for dimensional scaling, associative network building and functional clustering. Curated genes were correlated with the Mini-Mental State Examination and semantic, working and episodic memory, visuospatial ability, and a composite Global Cognitive Score. Regulatory mechanisms were determined by co-expression networks with microRNAs and an overlap of transcription factor binding sites. Analysis revealed 750 genes and 12 microRNAs significantly differentially expressed between Braak Stages I/II and III/IV and an associated six groups of transcription factor binding sites. Inputting significantly different gene/network data into a functional annotation clustering model revealed elevated presynaptic, postsynaptic and ATP-related expression in Braak Stages III and IV compared with Stages I/II, suggesting these pathways are integral for cognitive resilience seen in unimpaired elderly subjects. Principal component analysis and Kruskal–Wallis testing did not associate Braak stage with cognitive function. However, Spearman correlations between genes and cognitive test scores followed by network analysis revealed upregulation of classes of synaptic genes positively associated with performance on the visuospatial perceptual orientation domain. Upregulation of key synaptic genes suggests a role for these transcripts and associated synaptic pathways in cognitive resilience seen in elders despite Alzheimer disease pathology and dementia.

The pupil and myself: pupil dilation during retrieval of self-defining memories.

There is a recent interest in pupil dilation during the retrieval of autobiographical memory. We pursued this line of research by measuring pupil diameter during the retrieval of self-defining memories, that is, memories that are highly vivid, emotionally intense, and are retrieved to reflect enduring concerns in a person's life. We invited 40 participants to retrieve self-defining memories while their pupil activity was recorder with eye-tracking glasses. We analyzed memories regarding specificity (i.e., specific or general) and emotional valence (neutral, positive, negative, or mixed). Analysis demonstrated larger pupil diameter during the retrieval of specific than general self-defining memories. However, no significant differences in pupil diameter were observed across the four emotional categories of self-defining memories. The increased pupil size during retrieval of specific self-defining memories can be attributed to the autonoetic experience during retrieval of these memories and/or to the cognitive load as required to construct these memoires. By investigating pupil dilation during the retrieval of self-defining memories, our study provides an original, ecological, and reliable physiological assessment of these memories.

Effective psychological therapy for PTSD changes the dynamics of specific large-scale brain networks.

In posttraumatic stress disorder (PTSD), re‐experiencing of the trauma is a hallmark symptom proposed to emerge from a de‐contextualised trauma memory. Cognitive therapy for PTSD (CT‐PTSD) addresses this de‐contextualisation through different strategies. At the brain level, recent research suggests that the dynamics of specific large‐scale brain networks play an essential role in both the healthy response to a threatening situation and the development of PTSD. However, very little is known about how these dynamics are altered in the disorder and rebalanced after treatment and successful recovery. Using a data‐driven approach and fMRI, we detected recurring large‐scale brain functional states with high temporal precision in a population of healthy trauma‐exposed and PTSD participants before and after successful CT‐PTSD. We estimated the total amount of time that each participant spent on each of the states while being exposed to trauma‐related and neutral pictures. We found that PTSD participants spent less time on two default mode subnetworks involved in different forms of self‐referential processing in contrast to PTSD participants after CT‐PTSD (mtDMN+ and dmDMN+) and healthy trauma‐exposed controls (only mtDMN+). Furthermore, re‐experiencing severity was related to decreased time spent on the default mode subnetwork involved in contextualised retrieval of autobiographical memories, and increased time spent on the salience and visual networks. Overall, our results support the hypothesis that PTSD involves an imbalance in the dynamics of specific large‐scale brain network states involved in self‐referential processes and threat detection, and suggest that successful CT‐PTSD might rebalance this dynamic aspect of brain function.

The Mood Repair Effect of Positive Involuntary Autobiographical Memory Among Japanese Adults: An Experimental Study

Involuntary autobiographical memories are memories of personal events that come to mind without an intentional attempt at retrieval. Previous studies have shown that positive involuntary autobiographical memory retrieval improves negative mood, known as the mood repair effect, in daily life. However, the cues relating to involuntary autobiographical memories were not controlled in these previous studies, and the mood repair effect has not been shown experimentally. Therefore, this study aimed to experimentally examine the mood repair effect of positive involuntary autobiographical memory among Japanese adults. After a pilot study to select cue words, we examined whether positive involuntary autobiographical memory retrieval could improve negative mood. As a result, mood improvement was enhanced by positive memory being recalled involuntarily, while mood improvement was shown with and without the retrieval of the positive involuntary autobiographical memory. Therefore, the mood repair effect by positive IAM was shown even after preventing the influence of the emotional valence of retrieval cues. From these results, the mood repair effect of positive involuntary autobiographical memory retrieval was experimentally demonstrated among Japanese adults.