This paper presents results of topic modeling and network models of topics using the ICCS corpus, which contains domain-specific (computational science) papers over sixteen years (a total of 5695 papers). We discuss topical structures of ICCS, how these topics evolve over time in response to the topicality of various problems, technologies and methods, and how all these topics relate to one another. This analysis illustrates multidisciplinary research and collaborations among scientific communities, by constructing static and dynamic networks from the topic modeling results and the authors’ keywords. The results of this study give insights about the past and future trends of core discussion topics in computational science. We used the Non-negative Matrix Factorization(NMF) topic modeling algorithm to discover topics and labeled and grouped results hierarchically. We used Gephi to study static networks of topics, and an R library called DyA to analyze the dynamic networks of topics.