Conflicting Results Research Articles

Reducing the risk of onion bacterial diseases: A review of cultural management strategies

AbstractOnion (Allium cepa L.) bacterial diseases can cause catastrophic crop losses. Chemical and biological control products are not curative and have mixed or limited efficacy at preventing onion bacterial diseases. Cultural management strategies, such as appropriate irrigation and nitrogen (N) management practices, can reduce the risk for bacterial infection and disease progression. This review synthesizes available literature on cultural management strategies to mitigate onion bacterial diseases and identifies knowledge gaps, promising strategies, and limitations. This synthesis revealed that high N fertilizer application rates, the use of overhead irrigation, and late‐season irrigation or rainfall, especially during field curing, can increase bacterial disease pressure. These factors contribute to conducive conditions for bacteria to colonize the foliage and neck of onion plants. Other in‐season strategies, such as reducing the total amount of irrigation or adjusting application rates of nutrients other than N, have not limited losses to bacterial bulb rots while maintaining desired yields. At the end of the growing season, appropriate timing of lifting bulbs (undercutting to sever the roots) and other practices that speed field curing can reduce the risk of bacterial bulb rots. However, it is less clear if topping (removing foliage) before or after curing influences bacterial bulb rots. Conflicting results reported for some cultural management strategies indicate that local conditions, such as climate and soil types, must be considered for optimizing practices to manage onion bacterial diseases. Advancing our scientific understanding and grower awareness of strategies that reduce onion bacterial diseases is a cost‐effective opportunity to avoid losses.

Impact of caudal block on revision rates after hypospadias repair: Multi-institution review

There is controversy surrounding the association between caudal block and complication rates after hypospadias repair. Conflicting results have been reported mostly from single-center, low volume studies and those that did not include relevant variables. We hypothesized that caudal block is not associated with increased rates of reoperation after primary repair and is associated with more complex hypospadias surgery. The Clinical Practice Solutions Center database was queried to identify patients who received a primary hypospadias repair between 2009 and 2010. Primary hypospadias repair was further categorized as meatal advancement and glanduloplasty, distal, one-stage proximal, or one-stage perineal repair. Anesthesia coding was evaluated to identify those who received a caudal block. Any revision surgery was captured between 2009 and 2019 and the types of revision surgeries were identified. Variables such as caudal block, age, insurance type, surgeon volume, and surgeon years in practice were analyzed with mixed effects multiple logistic regression models. The dataset query identified 3343 pediatric males who had primary hypospadias repair. The procedures were performed by 50 surgeons at 27 hospitals. Primary surgeries included meatal advancement and glanduloplasty (23%), distal (69%), proximal (6.9%), and perineal repairs (1%). Caudal block was administered to 42% of patients. Utilization of caudal block was not associated with type of primary surgery (p=0.21). Adjusting for all other variables, increased patient age was associated with decreased usage of caudal block (p<0.001). Analysis did not demonstrate a statistically significant association between utilization of caudal block with rates of revision surgery. This large, multi-institution study demonstrates that the use of caudal block was not associated with more complex hypospadias surgery nor statistically significantly associated with increased rates of revision surgery after primary hypospadias repair.

Internet Gaming Disorder Does Not Predict Mood, Anxiety or Substance Use Disorders in University Students: A One-Year Follow-Up Study.

We seek to evaluate whether Internet Gaming Disorder (IGD) among university students in Mexico during their first year at university predicts a long list of mental disorders a year later, controlling for baseline mental health disorders as well as demographics. This is a prospective cohort study with a one-year follow-up period conducted during the 2018-2019 academic year and followed up during the 2019-2020 academic year at six Mexican universities. Participants were first-year university students (n = 1741) who reported symptoms compatible with an IGD diagnosis at entry (baseline). Outcomes are seven mental disorders (mania, hypomania, and major depressive episodes; generalized anxiety disorder and panic disorder; alcohol use disorder and drug use disorder), and three groups of mental disorders (mood, anxiety, and substance use disorders) at the end of the one-year follow-up. Fully adjusted models, that included baseline controls for groups of mental disorders, rendered all associations null. The association between baseline IGD and all disorders and groups of disorders at follow-up was close to one, suggesting a lack of longitudinal impact of IGD on mental disorders. Conflicting results from available longitudinal studies on the role of IGD in the development of mental disorders warrant further research.

The impacts of futures trading on volatility and volatility asymmetry of Bitcoin returns

The impact of Bitcoin futures introduction on the underlying Bitcoin volatility has been a controversial topic. Conflicting results had been obtained from different sample periods and methodologies. To address this debate, this study examines the impact of futures trading on volatility and volatility asymmetry of Bitcoin returns in the short and long run. Using exponential GARCH models, we introduce a dummy in the variance equation to capture the changes in the volatility after the introduction of Bitcoin futures. We find that after the introduction, spot return volatility decreases in the short run, but increases in the long run. Besides, in the short run, there exists an inverse leverage effect before and after the introduction; in the long run, the inverse leverage effect before the introduction changes to a usual level effect after the introduction. Finally, we examine whether greater futures trading activity, proxied by trading volume and open interest, is associated with greater Bitcoin volatility. To do so, we decompose each proxy into expected and unexpected components and document that, in the long run, Bitcoin volatility covaries positively with unexpected futures trading volume, but negatively with unexpected futures open interest.

Conflicting results on the role of ECG in risk-stratification for sudden cardiac death in childhood hypertrophic cardiomyopathy.

The research group at University College London introduced the concept of standardizing the quantification of risk by assessing risk of sudden death or equivalent malignant arrhythmia event occurring during the subsequent 5 years of follow-up after diagnosis. While the aims in the recent article by Norrish et al.1 published in this journal are laudable, it is imperative to highlight the methodological shortcomings underlying their analysis. The authors aim to assess the ability of the electrocardiogram (ECG) risk-score and other aspects of the 12-lead ECG to predict ‘major arrhythmic cardiac event’. They selected a subset (356/1029) of the multi-centre cohort of paediatric patients with hypertrophic cardiomyopathy (HCM) used to construct the HCM Risk-Kids algorithm, where ECGs had been archived. This subset however consisted mainly of recently recruited patients, and so median follow-up was only 3.9 years (interquartile range Q1–Q3 2.0–7.7).1 A major concern is that Norrish et al. did not restrict their analysis to include only those survivors who had reached 5 years of follow-up (n = 77 + 68 = 145), and the patients who had a ‘major arrhythmic cardiac event’ within 5 years of follow-up (n = 17). Instead they compared all patients without events, even if 25% of them had <2 years follow-up, with all patients who had major arrhythmic cardiac event, even if 8 of them had an event later than 5 years of follow-up. Thus, in fact, only 17 (patients with major arrhythmic cardiac event within 5 years) + 145 (patients with ≥5 years follow-up without event) = 162 of the patients are actually statistically informative about the end-point of major arrhythmic cardiac event within 5 years.1 This constitutes only 46% of the total ECG group analysed. The other 194 actually confuse the results as patients with high-risk ECG features and short follow-up might have had a major arrhythmic cardiac event later on within the 5-year span. Similarly, the ECGs of patients with major arrhythmic cardiac event after >5 years of follow-up might have evolved more ECG changes closer to the event as shown in other studies.2 Thus including these late major arrhythmic cardiac events will underestimate the sensitivity of the method.

Impact of the period of the day on all-cause mortality and major cardiovascular complications after arterial vascular surgeries.

Conflicting results are reported about daytime variation on mortality and cardiac outcomes after non-cardiac surgeries. In this cohort study, we evaluate whether the period of the day in which surgeries are performed may influence all-cause mortality and cardiovascular outcomes in patients undergoing non-cardiac arterial vascular procedures. 1,267 patients who underwent non-cardiac arterial vascular surgeries between 2012 and 2018 were prospectively included in our cohort and categorized into two groups: morning (7 a.m. to 12 a.m., 79%) and afternoon/night (12:01 p.m. to 6:59 a.m. in the next day, 21%) surgeries. Primary endpoint was all-cause mortality within 30 days and one year. Secondary endpoints were the incidence of perioperative myocardial injury/infarction (PMI), and the incidence of major adverse cardiac events (MACE, including acute myocardial infarction, acute heart failure, arrhythmias, cardiovascular death) at hospital discharge. After adjusting for confounders in the multivariable Cox proportional regression, all-cause mortality rates at 30 days and one year were higher among those who underwent surgery in the afternoon/night (aHR 1.6 [95%CI 1.1-2.3], P = 0.015 and aHR 1.7 [95%CI 1.3-2.2], P < 0.001, respectively). Afternoon/night patients had higher incidence of PMI (aHR 1.4 [95%CI 1.1-1.7], P < 0.001). There was no significant difference in the incidence of MACE (aHR 1.3 [95%CI 0.9-1.7], P = 0.074). In patients undergoing arterial vascular surgery, being operated in the afternoon/night was independently associated with increased all-cause mortality rates and incidence of perioperative myocardial injury/infarction.

Women-Headed Households: Diversity and Dynamics in Post-Conflict Settings in South Asia

Women-headed households have been reported to be emerging more than ever before in both developing and developed countries due to many reasons, from different factors affecting households in a country to regional and global determinants. This paper unpacks the diversity and dynamics of women-headed households in post-conflict contexts in South Asian countries, with a focus on Sri Lanka and Nepal using a feminist approach. Women-headed households have been reported to face higher levels of poverty than male-headed households in South Asia. There are compelling reasons to anticipate that a group of people who already experience social inequality because of their gender might also experience economic hardship. This paper discusses the challenges women face when heading households, their vulnerabilities, as well as their methods of overcoming the challenges as they take up household responsibilities in the absence of men. This paper also gives accounts of women heading households from their perspectives on how they manage the day-to-day running of the household and the challenges they face in a post-conflict setting. It concludes that the emergence of women-headed households are not only the result of conflict and that they are not a temporary aberration. The paper highlights the need to understand women-headed households in their unique settings, considering many factors that could influence their socioeconomic behaviour. Many of the household surveys fall short of analyzing the complexities associated with women-headed households and fail to identify uniqueness. Therefore, this paper argues the need for qualitative ethnographic data to understand the complexities of women-headed households. Ethnicity and cultural backgrounds need to be considered when analysing data on women-headed households as their dealings and experiences differ in the way these factors play in. This paper also emphasises the need for development practitioners to pay attention to the prevailing understandings of household headship and agency when devising policies to assist women-headed households.

Missed Connections in the U.N. Agenda: Applying the Women, Peace and Security Framework to the Feminization of Poverty

Women, Peace and Security, a multifaceted agenda intended to address the particular ways in which conflict affects women, has been on the United Nations agenda since the landmark Security Council Resolution 1325 passed in 2000. The unequal burden of poverty on women, a phenomenon that has been coined “the feminization of poverty,” has been on the United Nations agenda for even longer, since the 1995 Beijing Conference on Women. Yet, despite the fact that poverty and inequality both cause and result in conflict in a violent cycle, the problem of the feminization of poverty has not been integrated into the United Nation’s Women, Peace and Security agenda at large. This Note argues that the eradication of the gendered impact of poverty must be a central goal of the Women, Peace and Security agenda: first, to ensure the full enjoyment of women’s human rights, and second, because an agenda for peace can only be achieved by increasing gender equality and women’s political participation. This point is demonstrated through an analysis of the current system of international peacebuilding, which relies heavily on international financial institutions and perpetuates a neoliberal economy, to the detriment of both peace and women’s rights. This Note concludes that applying the framework of the four pillars of Women, Peace and Security (participation, protection, prevention, and post-conflict relief and recovery) can disrupt the cycles that perpetuate conflict and deny women equality, opportunity, and adequate living conditions.

Uneventful Phacoemulsification after Trabeculectomy in Pseudoexfoliation Glaucoma versus Primary Open-Angle Glaucoma

Introduction: Conflicting results have been reported on phacoemulsification in the filtered eyes with open-angle glaucoma. In this study, we aim to compare the effect of phacoemulsification after trabeculectomy between pseudoexfoliation glaucoma (XFG) and primary open-angle glaucoma (POAG). Methods: Consecutive patients with XFG and POAG who underwent uneventful phacoemulsification after trabeculectomy with 5-fluorouracil (TRAB-PHACO group) were reviewed retrospectively and matched to patients who underwent trabeculectomy only (TRAB group). Comparisons were performed for IOP, medication numbers, and success rates. Surgical failure was defined as IOP >21 mm Hg or IOP ≤21 mm Hg with additional medication or glaucoma surgery. Survival analysis was investigated by Kaplan-Meier test and the factors influencing final success by multivariate logistic regression analysis. Results: The records of 204 patients were reviewed. In XFG, when compared with the baseline, increase in IOP became statistically significant at the at 24-month visit in the TRAB-PHACO group (p = 0.002), at the 6-month visit (p = 0.001) in the TRAB group and remained so throughout the follow-up. In the TRAB-PHACO group, increase of glaucoma medications was statistically significant only at the last visit (p = 0.001) in XFG, at the 6-month visit (p = 0.02) in POAG and remained so throughout the follow-up. Two glaucoma types did not differ statistically from one another in terms of survival analysis. In the TRAB group, the additional glaucoma surgery was more common in XFG compared to POAG (p = 0.02). The trabeculectomy failure after phacoemulsification was related with an IOP spike >25 mm Hg at postoperative first 24h (p = 0.04). Conclusions: In the filtered eyes with XFG, uneventful phacoemulsification may delay time-related worsening in IOP control and may decrease the additional glaucoma surgery need.

Emergency airway management with the gum elastic bougie outside of the operating room: a narrative review

The ongoing coronavirus 2019 (COVID-19) pandemic has increased the need for healthcare professionals to perform emergency endotracheal intubation (ETI) in patients with COVID-19-related respiratory failure outside of the operating room. Difficult airways and severe airway-related adverse events occur much more frequently in such settings due to limited time and resources as well as the patient’s reduced physiological reserve. The gum elastic bougie (GEB) intubation tube is an inexpensive, simple, and readily transportable aid to intubation, but its effectiveness in emergency airway management has not been comprehensively evaluated in recent years. Here, we performed a literature review and have updated the available evidence on the utility of GEB in emergency airway management. After a systematic MEDLINE search, we identified 36 relevant reports that compared GEB with alternative airway management approaches in a variety of real-world and simulated settings. In most studies, GEB increased the first-pass ETI success rate and decreased the force applied on the tongue and incisors during laryngoscopy. GEB also increased the speed, safety, and reliability of emergency cricothyrotomy. Conflicting results were obtained in studies examining GEB use for ETI during cardiopulmonary resuscitation, and other special circumstances such as selective lung ventilation, the presence of vomitus, and the use of personal protective equipment. These results suggest that GEB use could be expanded beyond difficult airways and rescue after failed ETI attempts, but further studies will be necessary to determine the utility of GEB under special conditions. Because fatal airway-related adverse events can in part be attributed to limited accessibility of proper airway management equipment, devices such as GEB may increase successful outcomes, especially under the overwhelmingly challenging conditions imposed by the COVID-19 pandemic.

Inhibiting nighttime melatonin and boosting cortisol increase patrolling monocytes, phagocytosis, and myelination in a murine model of multiple sclerosis

Conflicting results on melatonin synthesis in multiple sclerosis (MS) have been reported due to variabilities in patient lifestyles, which are not considered when supplementing melatonin. Since melatonin acts through its receptors, we identified melatonin receptors in oligodendrocytes (OLs) in the corpus callosum, where demyelination occurs; the subventricular zone, where neural stem/progenitor cells (NSPCs) are located; and the choroid plexus, which functions as a blood-cerebrospinal fluid barrier. Moreover, using chimeric mice, resident macrophages were found to express melatonin receptors, whereas bone marrow-derived macrophages lost this expression in the demyelinated brain. Next, we showed that cuprizone-fed mice, which is an MS model, tended to have increased melatonin levels. While we used different approaches to alter the circadian rhythm of melatonin and cortisol, only the constant light approach increased NSPC proliferation and differentiation to oligodendrocyte precursor cells (OPCs), OPCs maturation to OLs and recruitment to the site of demyelination, the number of patrolling monocytes, and phagocytosis. In contrast, constant darkness and exogenous melatonin exacerbated these events and amplified monocyte infiltration. Therefore, melatonin should not be considered a universal remedy, as is currently claimed. Our data emphasize the importance of monitoring melatonin/cortisol oscillations in each MS patient by considering diet and lifestyle to avoid melatonin overdose.

Opravdanost vojne neutralnosti Republike Srbije u vremenu erozije neutralnosti u Evropi

This paper aims to examine the justifiableness of the Republic of Serbia's politics of military neutrality after the beginning of the Russo-Ukrainian conflict, i.e., in an era of extreme tensions between Western countries and Russia. The significance of this topic has been additionally elevated after two neutral countries, Sweden and Finland, renounced neutrality while debates about the appropriateness of neutrality emerged in other neutral countries, such are Ireland, Malta, and Austria. The purpose of the paper is to examine, from a perspective of sociology of politics, whether the position of military neutrality still represents a good foreign-policy strategy aiming to preserve sovereignty and territorial integrity. The hypothesis of this paper is that Serbia's military neutrality is justified by the social reality in Serbia. The first chapter briefly describes the historical decline of neutrality during the first half of the 20th century. In that context, observation made in mid last century, according to which neutrality was becoming an obsolete concept, is true. Increase of NATO members, as well as abandoning neutrality under the influence of globalization and negative experiences of neutral countries in the 20th century, strengthens this assertion. However, we can conclude that neutrality has existed in continuity in Europe throughout the entire modern period of history, and that there were always some states that chose neutrality, with larger or lesser prospects of success in realization of their security interests. The great revolution, one might say the collapse of neutrality or even a frenzy to align, was the result of the Russo-Ukrainian conflict and new increasing tensions between the West and Russia. The second chapter is dedicated to the causes of Serbia's decision to be military neutral. These causes include: internal division of key political acters in regards to strategic alignment, the issues of the status of Kosovo and Metohija in which the Russian Federation provides key support to Republic of Serbia in the United Nations, and the role of NATO in wars during the disintegration of Yugoslavia and currently in Kosovo and Metohija. The third chapter lists the advantages in regards to social values implied by the position of military neutrality. Authors conclude that military neutrality represents a favorable strategic option for the Republic of Serbia, not just due to painful collective memory of Serbian citizens of the NATO aggression on Yugoslavia and the support of the Russian Federation to Serbia in regards to Kosovo and Metohija, but also due to the intrinsic values of neutrality which could become an identity attribute and a foundation of the renewal of solidarity in Serbian society.

Demographic Aspects of Syria&amp;apos;s Socio-economic Recovery

The demographic aspects of countries and regions today is an important factor in their not only social, but also economic development and position in the world. Demographic trends are especially important for a state in whose territory, as in the Syrian People&amp;apos;s Republic (SAR), a military conflict continues, largely related to external intervention. Until 2011, i.e. before the outbreak of the military conflict, Syria remained one of the most economically developed countries in the West Asia region. But the result of the military conflict was numerous and serious demographic and socio-economic losses. Therefore, the author substantiates the point of view that among the most important tasks of the state remains the speedy restoration of not only the socio-economic sphere, but also positive demographic processes. The purpose of the article is to analyze the demographic situation in Syria in the XXI century, to identify the factors that influenced its formation and new trends and processes, their interrelation and interdependence. The research was carried out on the basis of statistical data provided by international organizations, primarily UNCTAD, for the period from 2000 to 2021, as well as on the basis of the analysis of available domestic and foreign scientific literature on the subject under consideration. The study showed that along with the growth of the share of the population of the SAR in regional indicators, the country retains significant specifics. The author notes, first of all, the preservation of relatively high birth rates of the population, a relatively low level of urbanization.

Religious and Political Identity and Activity of the “Shirazist” Movement

With the increasing politicization of the Middle East in general and shiites in particular, it is very relevant to study the religious and political features of one of the most influential movements in Shiite Islam — the movement of “Shirazists”. Unfortunately, little attention is paid to this transnational movement in comparison with other Shiite Islamist organizations and movements. This paper examines the origins of this transnational movement, its evolution and features. Special attention is paid to the evolution of the ideology of the “Shirazists” movement. The religious and political identity of this movement was the result of factional conflicts within Shiism, in particular the long-standing rivalry between the religious schools of Najaf and Karbala. The specifics of this movement are determined, as well as its differences and similarities with another transnational Shiite organization — Daava. The article also analyzes the activities of the movement in the Persian Gulf countries and the problems of the relationships between “Shirazists” and official authorities of Iran.

The aging process of deep fat compartments in the midface and midfacial rejuvenation: An ultrasound-based analysis

Abstract Background: The midfacial fat is highly compartmentalized, and the deep fat compartments provide structural support for the midface. Understanding the age-related changes in the midfacial deep fat compartments is important for midfacial rejuvenation physiologically. However, previous studies showed conflicted results of these changes. Objectives: This study aims to quantify the age-related changes of deep fat compartments in the midface using ultrasound. Methods: A cross-sectional study was conducted to evaluate subjects with age more than 25 years old and the subjects were divided into four age groups equally (25–34, 35–44, 45–54, and ≥55). The thickness of the suborbicularis oculi fat compartment (SOOF) and deep medial cheek fat compartment (DMCF) was measured using a portable ultrasound device. Mean thickness differences among different age groups were analyzed by one-way analysis of variance. Multiple linear regression adjusted for body mass index (BMI) and sex was also conducted. Results: A total of 60 subjects were enrolled. The thickness of SOOF and DMCF tends to decrease with age. The mean decrease of SOOF and DMCF from the youngest group to the oldest group was 0.63 mm (36%) and 0.70 mm (25.83%), respectively. The relationship between aging and thickness of SOOF and DMCF remains significant after adjusting for BMI and sex (both P &lt; 0.001). Conclusion: The thickness of deep fat compartments decreases with the natural aging process. The study may offer clinical implications for targeted volume rejuvenation to achieve a more youthful and natural face.

Heritage Industry, or Lithuanian Notions of the Manor in the 21st Century

For decades, the notion of a manor was basically unequivocal in the Lithuanian society – it was related to Polish influence (which means it is not ours, Lithuanian). This was the result of political and cultural conflicts between the two nations, a struggle for the power of expression of great narratives and historical memory. The manor with its history and heritage was depicted in negative or at least gloomy colors. Such notions dominated in the consciousness of Lithuanians almost during the whole 20th century. In the second half of the 1980s, the first seeds of alternative or novel notions of the manor emerged in Lithuania. In about 2000, the business discourse appropriated manor culture to create their own notion as developers of products and services for consumers. This paper presents the genesis of this notion, its peculiarities, expressions, and interactions with Lithuanian identity and historical memory.One of the conclusions of the research is that around 2010, a fundamental turning point occurred in the concept and notion of Lithuanian manors, as they came to be associated with native Lithuanian culture and identity – associated, yet not unconditionally accepted. The new role of the manor presents an interesting phenomenon. Manor culture is perceived as attractive because of its different, exotic, and unknown culture.

The Issue about the Provision for Damage Inflicted by Preventive Security Measures upon Adjudicating the Dispute over Legality of Enabling Individual Administrative-legal Acts

The Constitutional Court of Georgia considers the constitutional submission of Tbilisi Court of Appeals requesting to establish the constitutionality of inadmissibility of the reversal of provision upon applying the preventive security measures in the administrative process. &#x0D; The idea of admitting the reversal of provisional measures in the administrative proceedings of civil procedure standards aims at the maintenance of balance between the private interests of participants in the administrative process. However, it is impossible to speak about the methods and prospects of its implementation without the joint understanding of the enabling individual administrative-legal act as the essence of examining the result of conflict of interests, the legitimacy of state administration, the principle of legal trust and the major function of administrative justice at the stage of preventive security. &#x0D; The goal of this paper is to present certain viewpoints on the problematic aspects of admissibility of the reversal of civil security in administrative proceedings and their solutions pursuant to the principle of their legal trust.

Effect of periodontal disease on children with diabetes and their quality of life

Diabetes mellitus (DM) is a life-altering and comparatively prevalent chronic condition affecting children. The root cause of the condition is linked to the pancreatic islets of Langerhans, which produce the hormone insulin and are destroyed by an autoimmune inflammation. The illness then shows up clinically as a result. In the context of the combination of hereditary and external variables, the condition emerges in people with polygenic genetic susceptibility. Concerning a potential connection involving DM and periodontitis, many investigations have been released. Conflicting results, though, have been recorded. Certain authors believe that individuals with DM have significantly higher levels of gingival inflammation and marginal periodontitis than non-DM controls, despite the fact that this association has not been discovered in another research. Dental plaque microbes are the primary cause of periodontal pathologies, in which the tissues around the teeth become infected. Periodontitis manifests in DM patients earlier than it does in the general demographic of healthy individuals. Periodontal deterioration typically shows up in children with DM throughout puberty, while it can happen sooner. Also, in juvenile subjects with type 1 DM, the development of periodontal infection has been linked to poorly managed DM. Elevated access to glucose in both the fluid around the gingival crevice and saliva promotes the growth of caries and periodontal pathology causing microbes and worsens oral inflammation. Owing to inflammation, periodontal disease affects the cellular and humoral immune systems. The generation of insulin and metabolic control are impacted by these modifications in immune responses. Thus, periodontal disease can hinder glycemic control, and impaired metabolic control can further encourage periodontitis; a loop may be generated that worsens both problems. Hence, it is vital to prevent and manage oral inflammatory conditions in order to effectively prevent and control DM complications.

Acromial Morphology and Its Relation to the Glenoid Is Associated with Different Partial Rotator Cuff Tear Patterns

The pathogenesis of subacromial impingement syndrome is controversially discussed. Assuming that bursal sided partial tears of the supraspinatus tendons are rather the result of a direct subacromial impact, the question arises whether there is a morphological risk configuration of the acromion and its spatial relation to the glenoid. Patients who underwent arthroscopic repair of either a partial articular supraspinatus tendon avulsion (PASTA) or bursal-sided supraspinatus tear (BURSA) were retrospectively allocated to two groups. Various previously described and new omometric parameters on standard anteroposterior and axial shoulder radiographs were analyzed. We hypothesized that acromial shape and its spatial relation to the glenoid may predispose to a specific partial supraspinatus tendon tear pattern. The measurements included the critical shoulder angle (CSA), the acromion index (AI), Bigliani acromial type and the new short sclerotic line, acromioclavicular offset angle (ACOA), and AC offset. The ratio length/width of acromion and the medial acromial offset were measured on axial radiographs. A total of 73 patients were allocated to either PASTA (n = 45) or BURSA (n = 28). The short sclerotic line showed a statistically significant difference between PASTA and BURSA (16.2 mm versus 13.1 mm, p = 0.008). The ratio acromial width/length was statistically significant (p = 0.021), with BURSA having slightly greater acromial length (59 vs. 56 mm). The mean acromial offset was 42.9 mm for BURSA vs. 37.7 mm for PASTA (p = 0.021). ACOA and AC offset were both higher for BURSA, without reaching statistical significance. The CSA did not differ significantly between PASTA and BURSA (33.73° vs. 34.56°, p = 0.062). The results revealed an association between a narrow acromial morphology, increased medial offset of the acromion in relation to the glenoid, and the presence of a short sclerotic line in the anteroposterior radiograph in bursal-sided tears of the supraspinatus tendon. Assuming that bursal-sided tears are rather the result of a direct conflict of the tendon with the undersurface of the acromion, this small subgroup of patients presenting with impingement syndrome might benefit from removing a harming acromial spur.

Investigation of Spatial Coupling Coordination Development: Identifying Land System States from the Adaptation-Conflict Perspective.

With the advancement of global urbanization, ecosystem conservation and sustainable land development have become major issues. In this context, the uncoordinated and imbalanced development of the land-centered human-environment system requires urgent attention, especially in rust belt cities that pose critical challenges to regional land system sustainability. Therefore, taking Changchun City from 1990 to 2020 as an example, we identified and evaluated the ecosystem service (ES) balance and land use conflict from the perspectives of internal support and external development pressure. Based on the land system adaptation and conflict results, a coupling coordination degree model (CCDM) was constructed to investigate the spatio-temporal characteristics of land system development. The results indicated that there was an obvious downward trend in the regional ES balance, while areas with higher ES balance were mainly distributed in the eastern ecologically sound areas, and southern built-up areas presented deficient ES balance levels (i.e., demand exceeding supply), with a significant expansion trend from 1990 to 2020. Land use conflict was especially prominent in areas experiencing rapid rural-urban transformation, and the hot spots expanded noticeably. The spatio-temporal differences in the coupling coordination degree of ES balance and land use conflict were significant, whereas the land system of the study area has always been dominated by a balanced development pattern throughout the research period, except for the urban center, which tended to be in a stage of uncoordinated development, with the ES balance blocked. These findings suggest that it is necessary to coordinate urban and adjacent regions through regionally integrated efforts to alleviate the ES imbalance. This research can provide a scientific reference for analyzing regional land system states, coordinating the sustainable spatial development of ecosystems, and implementing revitalization strategies to achieve win-win land system goals.