“Two ecological barriers and three shelters” (TEBTS), which has the effect of relieving ecological pressure, is the national ecological security pattern in China. Calculating the value of TEBTS ecosystem services, clarifying the synergy/trade-off relationships between ecosystem services, and maximizing the value of regional ecosystem services are of great significance for maintaining the security of the ecological civilization. At present, the research on ecosystem service synergy/trade-off has become the frontier field of ecology and related disciplines at home and abroad, and many research results have been obtained. However, there is still room and significance for continuing research to think about the synergy/trade-off relationship of ecosystems from the perspective of temporal and spatial heterogeneity: clarifying the spatial scope and spatial transmission characteristics of ecosystem service synergy/trade-off; exploring the trend of ecosystem service synergy/trade-off, and simulating the dynamic characteristics of natural factors affecting ecosystem services; and analyzing the characteristics of different spatial attributes that lead to the synergy/trade-off of ecosystem services. In this study, the Songhua River Basin (SRB), where the NFB is located, is used as the research area, the ecosystem services are simulated through the ecosystem assessment model, ecological unit (EU) is constructed as a research carrier, which is used to define the spatial scope of ecosystem services, and the influence of spatial characteristics and attribute characteristics on the change trend of the ecosystem service synergy/trade-off relationship is analyzed. The research found that water retention, soil conservation, and biodiversity did not change much from 2000 to 2015, and these ecosystem services have a greater value in the NFZ. The amount of carbon sequestration increased rapidly from 2010 to 2015. Crop production showed an increasing trend year by year. As the main grain production area, the Songnen Plain provides the main crop production function, which is greatly affected by humans. In the spatial characteristic, water retention, soil sequestration, and biodiversity present a very significant synergistic relationship, which is manifested in the obvious high-value aggregation characteristics in the NFZ, and crop production and the other four types of ecosystem services are in a trade-off relationship. At the time scale, the four types of ecosystem services, including water retention, soil conservation, biodiversity, and carbon sequestration, are synergistic, and crop production and water retention are synergistic. The vegetation types exhibiting a synergy/trade-off relationship are mainly broad-leaved forests, and the soil types are mainly luvisols and phaeozems. These EUs are mainly distributed in the NFZ and have spatial topological characteristics: the area and circumference of these EUs are smaller, the radius of gyration is also significantly smaller than that of other EUs, and the shape is more regular. By focusing on the spatial aggregation characteristics and changing trends of the ecosystem service synergy/trade-off and clarifying the influencing factors of the ecosystem service synergy/trade-off, the ecosystem services can be integrated, and the ecosystem can be optimized. Thus, the value of regional ecosystem services can be maximized, and a certain data foundation and theoretical support can be provided for major projects, such as ecological restoration and ecological environment governance, which is of great significance for improving the pattern of ecological security.