ABSTRACTYouth experience numerous mental health and behavioral challenges in schools. School counselors are uniquely qualified to address these issues via prevention programming and interventions. This article discusses the behavioral Response to Intervention (RtI) framework and related three tiers of prevention that offer the early identification and support of students with more complex needs. We will also provide examples of evidence-based practices school counselors can incorporate in the delivery of services. These practices are universal, targeted, individualized, and rooted in research outcomes. Implications for school counseling research and practice are discussed.