This study used PGSI to measure the motives of online stock exchange gamblers according to their responses about their online gambling. The main aim of the current study is to holistically explore the impact of motivational factors that motivate more usage of online gambling in Pakistan and behavioral factors that investigate the level of implementation of responsible gambling practices on PGSI in Pakistan’s online stock exchange gamblers. We collected data through questionnaires and for analysis we used SEM, multiple regression and multinomial logistic regression. Results indicated that motivational factors that significantly impact PGSI are excitement, financial motivation, escape and relaxation and in terms of responsible gambling practices, game design and transparent terms and conditions are the key elements of behavioral factors while self-exclusion and self-help (SE and SH) are not considered as significant factors.