Time Frame Of Response Research Articles

Prevalence of Specific Mood Profile Clusters among Elite and Youth Athletes at a Brazilian Sports Club.

Those responsible for elite and youth athletes are increasingly aware of the need to balance the quest for superior performance with the need to protect the physical and psychological wellbeing of athletes. As a result, regular assessment of risks to mental health is a common feature in sports organisations. In the present study, the Brazil Mood Scale (BRAMS) was administered to 898 athletes (387 female, 511 male, age range: 12-44 years) at a leading sports club in Rio de Janeiro using either "past week" or "right now" response timeframes. Using seeded k-means cluster analysis, six distinct mood profile clusters were identified, referred to as the iceberg, surface, submerged, shark fin, inverse iceberg, and inverse Everest profiles. The latter three profiles, which are associated with varying degrees of increased risk to mental health, were reported by 238 athletes (26.5%). The prevalence of these three mood clusters varied according to the response timeframe (past week > right now) and the sex of the athletes (female > male). The prevalence of the iceberg profile varied by athlete sex (male > female), and age (12-17 years > 18+ years). Findings supported use of the BRAMS as a screening tool for the risk of psychological issues among athletes in Brazilian sports organisations.

Critical Inertia Calculation Method of Generators Using Energy Balance Condition in Power System

Critical inertia can be defined as the minimum kinetic energy stored in generators that should be kept for maintaining the frequency stability of the power system. As the frequency control performance of the power system is maintained according to its control criterion, during the inertia response time frame, the expected energy imbalance can be calculated by accumulating the imbalanced power caused by the credible contingency and calculating the available inertia response by considering the allowable operating limit of the frequency. Since the frequency control criterion can be met when the available inertia response becomes larger than the expected energy imbalance, the critical inertia can be calculated by the kinetic energy of the generators, of which the available inertia response is equal to the expected energy imbalance due to the contingency. With this in mind, this paper derives the energy balance condition for the frequency stability in the inertia response time frame based on the frequency control criterion and calculates the minimum inertia, which should be kept in the generators from the energy balance condition for meeting the criterion. In addition, the effectiveness of the proposed method is verified through various case studies employing Korean power systems.

Psychometric Characteristics of the Brazil Mood Scale among Youth and Elite Athletes Using Two Response Time Frames.

Regular assessment of the mood construct as an indicator of psychological wellbeing is used in Brazil to screen athletes for risk of mental health issues. The present study tested the psychometric characteristics of the Brazil Mood Scale (BRAMS) using both "right now" and "past week" response time frames and investigated between-group differences in mood based on athletes' sex, age, and social vulnerability. Participants were 898 athletes (511 male, 387 female, age range: 12-44 years) from eight sports. The factorial validity of the BRAMS was supported using both response time frames independently and in a multi-sample analysis. Subscale reliability was supported for both time frames. Fatigue, depression, and tension scores were higher using the "past week" time frame than the "right now" time frame. Males reported higher vigor scores than females, and younger participants (<18 years) reported lower scores for anger and depression than older participants (18+ years). No significant differences in mood (p > 0.05) were found between participants identified as socially vulnerable and those who were not socially vulnerable. Findings supported the psychometric integrity of the BRAMS and its use as a screening measure for psychological wellbeing among youth and elite athletes in Brazil.

Short-Term Adaptation of Dairy Cattle Production Parameters to Individualized Changes in Dietary Top Dress.

Simple Summary“Short-Term Adaptation of Dairy Cattle Production Parameters to Individualized Changes in Dietary Top Dress” focuses on feeding dairy cattle varying amounts of top dressed corn grain, soybean meal, or grass hay in order to obtain data on individual cow responses to be utilized for future development of individualized dairy precision feeding models. Precision feeding systems aimed at feeding dairy cattle individually to increase feed efficiency could contribute to profitability of dairies. The information provided in this study includes considerations of how we should design such systems.Immediate and short-term changes in diet composition can support individualized, real-time interventions in precision dairy production systems, and might increase feed efficiency (FE) of dairy cattle in the short-term. The objective of this study was to determine immediate and short-term effects of changes in diet composition on production parameters of dairy cattle fed varying amounts of top dressed commodities. A 4 × 4 replicated Latin square design was used to evaluate responses of twenty-four Holstein cows fed either no top dress (Control) or increasing amounts of: corn grain (CG), soybean meal (SBM), or chopped mixed grass hay (GH) top dressed on a total mixed ration (TMR) over four, 9-day periods. Throughout each period, top dressed commodities were incrementally increased, providing 0% to 20% of calculated net energy of lactation (NEL) intake. Measured production responses were analyzed for each 9-d period using a mixed-effects model considering two different time ranges. Samples collected from d 3 and 4 and from d 7 and 8 of each period were averaged and used to reflect “immediate” vs. “short-term” responses, respectively. In the immediate response time frame, control fed cows had lower milk yield, milk fat yield, and milk true protein yield than CG and SBM supplemented animals but similar responses to GH supplemented animals. Milk fat and protein percentages were not affected by top dress type in the immediate term. In the short-term response time-frame, GH supplemented animals had lower DMI and milk fat yield than all other groups. Control and GH supplemented cows had lower milk yield than CG and SBM fed cows. In the immediate response time frame, FE of SBM supplemented cows was superior to other groups. In the short-term time frame, FE of GH and SBM groups was improved over the control group. Results suggest that lactating dairy cows show rapid performance responses to small (<20% NEL) changes in dietary composition, which may be leveraged within automated precision feeding systems to optimize efficiency of production. Before this potential can be realized, further research is needed to examine integration of such strategies into automatic feeding systems and downstream impacts on individual animal FE and farm profitability.

Online microbial monitoring of drinking water: How do different techniques respond to contaminations in practice?

Safeguarding the microbial water quality remains a challenge for drinking water utilities, and because of population growth and climate change, new issues arise regularly. To overcome these problems, biostable drinking water production and water reuse will become increasingly important. In this respect, high-resolution online microbial monitoring during treatment and distribution could prove essential. Here, we present the first scientific and practical comparison of multiple online microbial monitoring techniques in which six commercially available devices were set up in a full-scale drinking water production plant. Both the devices’ response towards operational changes and contaminations, as well as their detection limit for different contaminations were evaluated and compared. During normal operation, all devices were able to detect abrupt operational changes such as backwashing of activated carbon filters and interruption of the production process in a fast and sensitive way. To benchmark their response to contaminations, the calculation of a dynamic baseline for sensitive separation between noise and events is proposed. In order of sensitivity, enzymatic analysis, ATP measurement, and flow cytometric fingerprinting were the most performant for detection of rain- and groundwater contaminations (0.01 – 0.1 v%). On the other hand, optical classification and flow cytometric cell counts showed to be more robust techniques, requiring less maintenance and providing direct information about the cell concentration, even though they were still more sensitive than plate counting. The choice for a certain technology will thus depend on the type of application and is a balance between sensitivity, price and maintenance. All things considered, a combination of several devices and use of advanced data analysis such as fingerprinting may be of added value. In general, the strategic implementation of online microbial monitoring as early-warning system will allow for intensive quality control by high-frequency sampling as well as a short event response timeframe.

The Marine Salvage Industry: Proven in Preventing Oil Spills

Abstract The marine salvage industry plays a vital role in protecting the marine environment. Governments, industry and the public, worldwide, now place environmental protection as the driving objective, second only to the safety of life, during a marine casualty response operation. Recognizing over 20 years after the passage of the Oil Pollution Act of 1990 that the effectiveness of mechanical on-water oil recovery remains at only about 10 to 25 percent while the international salvage industry annually prevents over a million tons of pollutants from reaching the world's oceans, ten years ago the United States began implementing a series of comprehensive salvage and marine firefighting regulations in an effort to improve the nation's environmental protection regime. These regulations specify desired response timeframes for emergency salvage services, contractual requirements, and criteria for evaluating the adequacy of a salvage and marine firefighting service provider. In addition to this effort to prevent surface oil spills, in 2016, the U.S. Coast Guard also recognized the salvage industries advancements in removing oil from sunken ships and recovering submerged pollutants, issuing Oil Spill Removal Organization (OSRO) classification standards for companies that have the capabilities to effectively respond to non-floating oils. Ten years after the implementation of the U.S. salvage and marine firefighting regulatory framework, this paper will review the implementation of the U.S. salvage and marine firefighting regulations and non-floating oil detection and recovery requirements; analyze the impacts and effectiveness of these new policies; and present several case studies and recommendations to further enhance salvage and oil spill response effectiveness.

Longitudinal saliva omics responses to immune perturbation: a case study

Saliva omics has immense potential for non-invasive diagnostics, including monitoring very young or elderly populations, or individuals in remote locations. In this study, multiple saliva omics from an individual were monitored over three periods (100 timepoints) involving: (1) hourly sampling over 24 h without intervention, (2) hourly sampling over 24 h including immune system activation using the standard 23-valent pneumococcal polysaccharide vaccine, (3) daily sampling for 33 days profiling the post-vaccination response. At each timepoint total saliva transcriptome and proteome, and small RNA from salivary extracellular vesicles were profiled, including mRNA, miRNA, piRNA and bacterial RNA. The two 24-h periods were used in a paired analysis to remove daily variation and reveal vaccination responses. Over 18,000 omics longitudinal series had statistically significant temporal trends compared to a healthy baseline. Various immune response and regulation pathways were activated following vaccination, including interferon and cytokine signaling, and MHC antigen presentation. Immune response timeframes were concordant with innate and adaptive immunity development, and coincided with vaccination and reported fever. Overall, mRNA results appeared more specific and sensitive (timewise) to vaccination compared to other omics. The results suggest saliva omics can be consistently assessed for non-invasive personalized monitoring and immune response diagnostics.

Virtual Inertia Control of Variable Speed Heat Pumps for the Provision of Frequency Support

The growth in the integration of converter interfaced renewable energy has reduced the system inertia, which threatens system stability due to high rate of change of frequency (RoCoF) and frequency nadir issues unless steps are taken to mitigate it. There is a need to provide sufficient fast frequency response to maintain adequate inertia in the system. This paper investigates the capabilities of a variable speed heat pump to provide an emulated inertial response. This paper presents a virtual synchronous machine control for a variable speed heat pump that provides support for grid frequency regulation over the inertial response time frame. A small-signal model with the transfer function of the variable speed heat pump is developed to analyse the effectiveness and feasibility of providing virtual inertia at the device and grid level, respectively. Furthermore, the small-signal model is validated using hardware in the loop simulation. Finally, the aggregated frequency response and virtual inertia contribution by a population of the heat pumps are evaluated and quantified in an urban distribution system.

High-density electromyographic assessment of stretch reflex activity during drop jumps from varying drop heights

This study investigated how drop heights and their associated drop jump performance relate to stretch reflex modulations. Eleven male subjects performed ten drop jumps from each of three individually predetermined drop heights. These were the drop height resulting in maximal performance (OPT), as well as 10 cm below (LOW) and above (HIGH) maximal performance. To quantify drop jump performance the reactive strength index, derived from force plate measures, was used. High-density surface EMG provided both stretch reflex response timing and size, as well as novel insight into the associated motor unit recruitment via muscle fiber conduction velocity estimations. These measures were examined in the vastus lateralis (VL), soleus (SOL) and gastrocnemius medialis (GM).Drop jump performance improved by 9% (p < 0.001) from LOW to OPT and decreased by 5% (p = 0.008) from OPT to HIGH. Despite decreasing performance, stretch reflex responses were largest at HIGH. Stretch reflex responses timing did not change; staying within the short (SOL, <60 ms) and medium (VL, GM; 60–85 ms) latency response time-frames. Motor unit recruitment appeared to change across drop heights only for VL, whereas activation intensity only changed for SOL. These results indicate that during drop jumps above OPT neuromuscular modifications result in VL no longer being maximally recruited.

Factor structure of mood over time frames and circumstances of measurement: Two studies on the Profile of Mood States questionnaire.

This paper presents the results of two studies on the invariance of the Profile of Mood States questionnaire across response time frames and circumstances of administration. We applied Spanish versions of the instrument to gather data from 1146 athletes. In the first study (N = 700), we tested the factor structure of the questionnaire in training sessions by using two different time frames: ‘right now’ (n = 350) and ‘past week’ (n = 350). In the second study (N = 446), we compared the factor structure of the questionnaire with data collected using the instruction ‘right now’ at two different circumstances: ‘training’ (n = 223) and ‘competition’ (n = 223). Data analysis was similar in both studies. We conducted multi-group confirmatory factor analyses and applied the scaled difference chi-square statistic to examine whether discrepancies in successive constrained models were significant. We observed configural equivalence between the two time frames. Furthermore, we observed metric equivalence but not scalar invariance between the different circumstances of measurement. The findings highlight the need for studies of equivalence before using a single self-report with more than one set of instructions, or under diverse circumstances. Invariance of mood scores should be examined and taken into account when interpreting individual and group mood state assessments.

Is There a Gender Difference in Cyber-Victimization?

Abstract. The study provides a quantitative synthesis of the literature on gender difference in cyber-victimization (CV). A total of 40 usable research articles were identified and used in this meta-analysis. With some articles having multiple effect sizes, a total of 150 effect sizes for gender difference in CV were obtained. Results indicated a small gender difference, with females experiencing slightly more CV than their male counterparts. However, there were considerable inconsistencies across the studies. Follow-up analyses on the study features revealed that several factors, such as response time frame and region of sampling, significantly moderated the relationship between gender and CV. Exploratory in nature, this study discusses the implications of the findings in reference to existing theories, and suggests future research directions.

The use of historical environmental monitoring data to test predictions on cross-scale ecological responses to alterations in river flows

Determination of ecological responses to river flows is fundamental to understanding how flow-dependent ecosystems have been altered by regulation, water diversions and climate change, and how to effect river restoration. Knowledge of ecohydrological relationships can support water management and policy, but this is not always the case. Management rules have tended to be developed ahead of scientific knowledge. The lag between practice and knowledge could be addressed by using historical monitoring data on ecological responses to changes in flows to determine significant empirical ecohydrological relationships, as an adjunct to investigating responses prospectively. This possibility was explored in the Murray–Darling Basin, Australia. We assessed 359 data sets collected during monitoring programs across the basin. Of these, only 32 (9%) were considered useful, based on a match between the scale at which sampling was done and ecological responses are likely to occur, and used to test flow–ecology predictions for phytoplankton, macroinvertebrates, fishes, waterbirds, floodplain trees, basin-scale vegetation and estuarine biota. We found relationships between flow and ecological responses were likely to be more strongly supported for large, long-lived, widespread biota (waterbirds, basin-scale vegetation, native fishes), than for more narrowly distributed (e.g. estuarine fishes) or smaller, short-lived organisms (e.g. phytoplankton, macroinvertebrates). This pattern is attributed to a mismatch between the design of monitoring programs and the response time frames of individual biota and processes, and to the use of local river discharge as a primary predictor variable when, for many biotic groups, other predictors need to be considered.

Routine to Rare Risk - A Case Study of Firecracker Explosion Disaster in India.

Introduction:In India quite a few religious festivals and cultural fairs are accompanied by public display of fireworks. The grandeur of the festivals is often evaluated by the common man with respect to its colorful firework displays. Firecracker accidents during mass fireworks at public display venues may be disastrous in its consequences and damages. A fire cracker disaster which occurred during a religious public firework display event at Puttingal in Kerala, India was documented and analyzed to figure out the safety concerns and good practices, towards making a reference for effective emergency management.Methods:The fire cracker incident was studied on the broader perspective of disaster management. Inputs from agencies involved in emergency response, casualty management, damage assessment and general administration as well as the perspective of victims and the public who witnessed the event was incorporated in to the study through participatory observation, field visits and face to face discussions.Result:The response followed by the firecracker explosion was analyzed in three phases based on the time frame of response. Influence of traditions and culture in firework organization, the mandatory legal requirements for firework displays and the current safety practices followed were evaluated in the background of this rare firecracker risk which turned out to be a major disaster in the state of Kerala in India.Conclusion:Public display of fireworks in Puttingal temple was organised despite of the legal permission from competitive authority. Negligence of law, non-sensitivity of public towards fire work safety, competitive nature of event organizers and social pressure from religious groups traversed the basic fire work safety requirements, ultimately triggered the largest fire cracker disaster in Kerala.

Options and uncertainties in planetary defense: Mission planning and vehicle design for flexible response

This paper is part of an integrated study by NASA and the NNSA to quantitatively understand the response timeframe should a threatening Earth-impacting near-Earth object (NEO) be identified. The two realistic responses considered are the use of a spacecraft functioning as either a kinetic impactor or a nuclear explosive carrier to deflect the approaching NEO. The choice depends on the NEO size and mass, the available response time prior to Earth impact, and the various uncertainties. Whenever practical, the kinetic impactor is the preferred approach, but various factors, such as large uncertainties or short available response time, reduce the kinetic impactor's suitability and, ultimately, eliminate its sufficiency.Herein we examine response time and the activities that occur between the time when an NEO is recognized as being a sufficient threat to require a deflection and the time when the deflection impulse is applied to the NEO. To use a kinetic impactor for successful deflection of an NEO, it is essential to minimize the reaction time and maximize the time available for the impulse delivered to the NEO by the kinetic impactor to integrate forward in time to the eventual deflection of the NEO away from Earth impact.To shorten the response time, we develop tools to survey the profile of needed spacecraft launches and the possible mission payloads. We further present a vehicle design capable of either serving as a kinetic impactor, or, if the need arises, serving as a system to transport a nuclear explosive to the NEO. These results are generated by analyzing a specific case study in which the simulated Earth-impacting NEO is modeled very closely after the real NEO known as 101955 Bennu (1999 RQ36). Bennu was selected for our case study in part because it is the best-studied of the known NEOs. It is also the destination of NASA's OSIRIS-REx sample return mission, which is, at the time of this writing, enroute to Bennu following a September 2016 launch.

Evaluating the cascading impacts of sea level rise and coastal flooding on emergency response spatial accessibility in Lower Manhattan, New York City

This paper describes a scenario-based approach for evaluating the cascading impacts of sea level rise (SLR) and coastal flooding on emergency responses. The analysis is applied to Lower Manhattan, New York City, considering FEMA’s 100- and 500-year flood scenarios and New York City Panel on Climate Change (NPCC2)’s high-end SLR projections for the 2050s and 2080s, using the current situation as the baseline scenario. Service areas for different response timeframes (3-, 5- and 8-min) and various traffic conditions are simulated for three major emergency responders (i.e. New York Police Department (NYPD), Fire Department, New York (FDNY) and Emergency Medical Service (EMS)) under normal and flood scenarios. The modelling suggests that coastal flooding together with SLR could result in proportionate but non-linear impacts on emergency services at the city scale, and the performance of operational responses is largely determined by the positioning of emergency facilities and the functioning of traffic networks. Overall, emergency service accessibility to the city is primarily determined by traffic flow speed. However, the situation is expected to be further aggravated during coastal flooding, with is set to increase in frequency and magnitude due to SLR.

Multiple myeloma and bone marrow mesenchymal stem cells' crosstalk: Effect on translation initiation.

Multiple myeloma (MM) malignant plasma cells reside in the bone marrow (BM) and convert it into a specialized pre-neoplastic niche that promotes the proliferation and survival of the cancer cells. BM resident mesenchymal stem cells (BM-MSCs) are altered in MM and in vitro studies indicate their transformation by MM proximity is within hours. The response time frame suggested that protein translation may be implicated. Thus, we assembled a co-culture model of MM cell lines with MSCs from normal donors (ND) and MM patients to test our hypothesis. The cell lines (U266, ARP-1) and BM-MSCs (ND, MM) were harvested separately after 72 h of co-culture and assayed for proliferation, death, levels of major translation initiation factors (eIF4E, eIF4GI), their targets, and regulators. Significant changes were observed: BM-MSCs (ND and MM) co-cultured with MM cell lines displayed elevated proliferation and death as well as increased expression/activity of eIF4E/eIF4GI; MM cell lines co-cultured with MM-MSCs also displayed higher proliferation and death rates coupled with augmented translation initiation factors; in contrast, MM cell lines co-cultured with ND-MSCs did not display elevated proliferation only death and had no changes in eIF4GI levels/activity. eIF4E expression was increased in one of the cell lines. Our study demonstrates that there is direct dialogue between the MM and BM-MSCs populations that includes translation initiation manipulation and critically affects cell fate. Future research should be aimed at identifying therapeutic targets that may be used to minimize the collateral damage to the cancer microenvironment and limit its recruitment into the malignant process. © 2015 Wiley Periodicals, Inc.

Chronic non-specific cough in children

Non-specific chronic cough refers to cough of more than 4 weeks duration with no symptoms or signs suggestive of a likely underlying problem. Management of children with chronic cough includes: an evaluation for these symptoms and signs; a chest radiograph and spirometry (where age-appropriate); as well as an assessment of environmental factors (in particular tobacco smoke), parental concerns and expectations. As the aetiology and management of cough in children differs greatly to that in adults, the empirical approach commonly used in adults is unsuitable for children. Treatment for chronic cough in children should be based on aetiology. Over-the-counter and prescription medications are ineffective and should be rarely used for the symptomatic relief of cough. Because of the favourable natural history of non-specific cough, if medication trials are undertaken, a ‘positive’ response should not be assumed to be due to the medication tried. Children should be re- assessed within the expected timeframe of response to therapy. This article reviews the management of children with cough, focusing on non-specific cough.

Symptom Cluster Research: Conceptual, Design, Measurement, and Analysis Issues

Cancer patients may experience multiple concurrent symptoms caused by the cancer, cancer treatment, or their combination. The complex relationships between and among symptoms, as well as the clinical antecedents and consequences, have not been well described. This paper examines the literature on cancer symptom clusters focusing on the conceptualization, design, measurement, and analytic issues. The investigation of symptom clustering is in an early stage of testing empirically whether the characteristics defined in the conceptual definition can be observed in cancer patients. Decisions related to study design include sample selection, the timing of symptom measures, and the characteristics of symptom interventions. For self-report symptom measures, decisions include symptom dimensions to evaluate, methods of scaling symptoms, and the time frame of responses. Analytic decisions may focus on the application of factor analysis, cluster analysis, and path models. Studying the complex symptoms of oncology patients will yield increased understanding of the patterns of association, interaction, and synergy of symptoms that produce specific clinical outcomes. It will also provide a scientific basis and new directions for clinical assessment and intervention.

Structural, Functional, and Phylogenetic Characterization of a Large CBF Gene Family in Barley

CBFs are key regulators in the Arabidopsis cold signaling pathway. We used Hordeum vulgare (barley), an important crop and a diploid Triticeae model, to characterize the CBF family from a low temperature tolerant cereal. We report that barley contains a large CBF family consisting of at least 20 genes (HvCBFs) comprising three multigene phylogenetic groupings designated the HvCBF1-, HvCBF3-, and HvCBF4-subgroups. For the HvCBF1- and HvCBF3-subgroups, there are comparable levels of phylogenetic diversity among rice, a cold-sensitive cereal, and the cold-hardy Triticeae. For the HvCBF4-subgroup, while similar diversity levels are observed in the Triticeae, only a single ancestral rice member was identified. The barley CBFs share many functional characteristics with dicot CBFs, including a general primary domain structure, transcript accumulation in response to cold, specific binding to the CRT motif, and the capacity to induce cor gene expression when ectopically expressed in Arabidopsis. Individual HvCBF genes differed in response to abiotic stress types and in the response time frame, suggesting different sets of HvCBF genes are employed relative to particular stresses. HvCBFs specifically bound monocot and dicot cor gene CRT elements in vitro under both warm and cold conditions; however, binding of HvCBF4-subgroup members was cold dependent. The temperature-independent HvCBFs activated cor gene expression at warm temperatures in transgenic Arabidopsis, while the cold-dependent HvCBF4-subgroup members of three Triticeae species did not. These results suggest that in the Triticeae - as in Arabidopsis - members of the CBF gene family function as fundamental components of the winter hardiness regulon.

Influence of response time frame on mood assessment

The present study compared mood assessments using two different response time frames. A sample of 136 school children completed the Brunel Mood Scale (BRUMS) daily for 5 days using the response time frame, “How are you feeling right now?” On Day 5, participants completed an additional BRUMS, using the response time frame, “How have you felt over the past week including today?”. “Past week” mood assessments yielded higher scores than multiple “right now” assessments, and were particularly associated with ambient mood for confusion, depression, and vigour. Researchers should give due consideration to the influence of response time frame on mood assessments.