Resonance Imaging In Prenatal Diagnosis Research Articles

Diagnostic accuracy of ultrasound and magnetic resonance imaging in prenatal diagnosis of abnormal placentation

Diagnostic accuracy of ultrasound and magnetic resonance imaging in prenatal diagnosis of abnormal placentation

Accuracy of Magnetic Resonance Imaging in Prenatal Diagnosis of Choledochal Cysts: A Single-Center Retrospective Analysis.

Background The purpose of this study is to evaluate the accuracy of prenatal MRI in diagnosing choledochal cysts (CDC), evaluate the sensitivity and specificity of MRI signs in the diagnosis of fetal CDC, and first compare the trend of size of CC between prenatal and postpartum. Methods A total of 18 fetal who were diagnosed with CDCs through prenatal MRI were enrolled in the study. We summarized and analyzed the prenatal clinical data and prognosis information of prenatal and postpartum surgery, then compared the sensitivity, specificity, and diagnostic accuracy of various signs of MRI and postpartum MRCP diagnosis of CC. Finally, we tried to compare the earliest prenatal detection of common bile duct cysts with the size of surgery, and calculated the growth rate of common bile duct cysts for the first time. Results All 18 patients were delivered in our institution. Among these patients, 14 were confirmed with CDCs after postpartum surgery, two patients had CDCs that disappeared, and two patients were confirmed with cystic biliary atresia (CBA) through the Kasai operation. Furthermore, 13 patients with CDCs and two patients with CBA underwent MRCP before the operation, and one patient with CDCs ruptured at birth and underwent ultrasound diagnosis. The sensitivity and diagnostic compliance of prenatal MRI signs for the location were higher when compared to postnatal MRCP (100% vs. 76.9% and 83.3% vs. 66.7%): the cyst was located at the porta hepatis, which was higher than the lowest edge of the liver, and parallel to the hepatoduodenal ligament. Conclusion Prenatal MRI is higher than that of US for diagnosing CDCs, specifically in identifying the location of the cyst and confirming the origin of the cyst. The length, width, and size of the CDC become slightly bigger in our study.

Application of Scanning Magnetic Resonance Imaging in the Diagnosis of Prenatal Placental Implantation and Related Care.

In order to solve the problem of scanning magnetic resonance imaging in prenatal diagnosis, the application and research of placental implantation have been proposed. Placental implantation is a serious obstetric emergency, which refers to the abnormal attachment of placental villi caused by the dysplasia of decidual basal layer. A study from the United States showed that the incidence of placental implantation in pregnant women during delivery increased from 9.9/30000 to 11.6/20000 from 2006 to 2019, which increased the risk of prenatal or postpartum hemorrhage, hysterectomy, stillbirth, abdominal organ injury, and so on. Clinically, patients can show severe prenatal or postpartum hemorrhage, postpartum placental retention, uterine perforation, and secondary infection, which may seriously endanger the lives of pregnant mothers and fetuses. Placental implantation can also have no obvious symptoms before delivery, which leads to insufficient prenatal diagnosis. Gielchinsky retrospectively studied 410 patients with placental implantation and found that only 9 patients were detected by prenatal ultrasound or magnetic resonance imaging (MRI), and the detection rate was only 6.6%. It can be seen that if the accurate diagnosis of placental implantation can be made before prenatal or symptoms appear, clinical intervention treatment can be carried out in time to reduce the probability of hysterectomy and improve the examination means of patients' prerecovery. At present, studies at home and abroad suggest that it has good clinical application value and research prospect in the clinical diagnosis of placental implantation.

Utility of placental diffusion-weighted magnetic resonance imaging in prenatal diagnosis of small for gestational age infants and pregnancy outcome prediction

IntroductionUltrasound-diagnosed small for gestational age (SGA) has a particular rate of misdiagnosis. We hypothesized that diffusion-weighted magnetic resonance imaging (MRI), specifically intravoxel incoherent motion (IVIM) imaging, could identify false-positive SGA (fpSGA). MethodsA prospective study. Placentas were scanned at gestational weeks 28–41 on a 3.0 T MRI using 9 b-values (0–800 s/mm2). Pregnancies were suspected as complicated by SGA when fortnightly ultrasound biometries confirmed that estimated fetal weights (EFW) were <10th percentile, while final birth weight >10th percentile was considered fpSGA. A total of 28 control, 20 fpSGA and 27 SGA patients were included. The mean values of the diffusion coefficient (D), pseudodiffusion coefficient (D*) and perfusion fraction (f) were calculated and compared between groups. ResultsIn the control and fpSGA groups, D (control, 1866.61 ± 213.74 μm2/s; fpSGA, 1807.37 ± 199.89 μm2/s), D* (control, 54833.29 ±s 8174.20 μm2/s; fpSGA, 52689.20 ± 9420.63 μm2/s) and f (control, 33.31% ± 3.49%; fpSGA, 33.17% ± 2.96%) were similar. However, all three were significantly lower in the SGA group (D, 1664.32 ± 288.53 μm2/s; D*, 48279.82 ± 7497.36 μm2/s; f, 27.53% ± 3.52%) than in the other two groups (p < 0.05). The f was the best parameter in distinguishing the control and SGA groups, and the fpSGA and SGA groups. DiscussionIVIM analysis might be suitable for the noninvasive identification of fpSGA pregnancies and SGA patients as an important supplement to ultrasound biometry.

Utility of Ultrasound and Magnetic Resonance Imaging in Prenatal Diagnosis of Placenta Accreta: A Prospective study

Objectives: determine the utility of ultrasound and magnetic resonance imaging in prenatal diagnosis of placenta accreta. Methods: Thirty patients presented in the department of gynecology and obstetrics and fulfilling the inclusion criteria were selected for the study. Study was a cros sectional design conducted at department of Radiology, Nishtar Hospital Multan, from 1st January 2019 to 1st December 2019. Result: Only 10 patients with placenta accreta were positive on USG while other 9 patients were found to be negative; and 3 patients were misdiagnosed to have placenta accreta on USG. Table-IIOnly 15 patients with placenta accreta were positive on MRI while other 4 patients were found to be negative; and 2 patients were misdiagnosed to have placenta accreta on USG. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 52.6%, 72.7%, 76.9%, respectively. Conclusion: It can be concluded that there is no significant difference between MRI and USG in terms of accuracy for prenatal diagnosis of placenta accreta.

The Role of Fetal Magnetic Resonance Imaging in Prenatal Diagnosis

ÖZET Amaç Üçüncü basamak merkezimizde klinisyenler tarafından tercih edilen fetal MRG endikasyonlarının incelenmesi ve MRG’nin ultrason bulgularına olan ek tanısal katkısının ortaya konmasıdır. Gereç ve Yöntem 2016-2018 yılları arasında fetal MRG yapılan 322 olgu retrospektif olarak incelendi. Fetal lezyonlar organ sistemlerine göre sınıflandırıldı ve klinisyenlerin endikasyonları belirlendi. Prenatal dönemde yapılan fetal ultrason ve MRG sonuçları değerlendirildi. Bulgular MRG çekilen 322 fetüsün endikasyonlarının dağılımı; 138’inde (%42.8) santral sinir sistemi anomalileri, 99’unda (%30.7) plasental anomaliler, 36’sında (%11.2) genitoüriner sistem anomalileri, 18’inde (%5.6) solunum sistemi anomalileri, 17’sinde (%5.3) maternal faktör, 13’ünde (%4) baş, boyun, yüz anomalileri ve 1’inde (%0.4) fetal faktör olarak belirlendi.Tüm endikasyonlar incelendiğinde MRG ile ek bulgu saptanan olgu sayısı 13’tür (%4.03). Santral sinir sistemi anomalileri 7 olgu ile en sık ek bulgu saptanan gruptur, bu grup içerisinde fetal MRG %5.07 oranında ek katkı sunmuştur. Sırasıyla genitoüriner sistem anomalileri olan grupta 3 ek bulgu (%8.33 oranında ek katkı), maternal endikasyonlar grubunda 2 ek bulgu (%11.7 oranında ek katkı) ve solunum sistemi anomalileri olan grupta 1 ek bulgu (%5.55 oranında ek katkı) olduğu görüldü. Sonuç Ultrasonografinin yetersiz kaldığı hallerde uygun perinatal yönetim ve danışmanlık için fetal MRG giderek artan sıklıkta kullanılmaktadır. MR cihazlarının daha ulaşılabilir olması, bu alandaki uzmanlığın artması ve MRG teknolojisindeki ileri gelişmeler, bu modalitenin perinatoloji alanında daha yaygın kullanımı ile sonuçlanacaktır.

Utility of ultrasound and magnetic resonance imaging in prenatal diagnosis of placenta accreta: A prospective study.

Context:Placenta accreta is the abnormal adherence of the placenta to the uterine wall and the most common cause for emergency postpartum hysterectomy. Accurate prenatal diagnosis of affected pregnancies allows optimal obstetric management.Aims:To summarize our experience in the antenatal diagnosis of placenta accreta on imaging in a tertiary care setup. To compare the accuracy of ultrasound (USG) with color Doppler (CDUS) and magnetic resonance imaging (MRI) in prenatal diagnosis of placenta accreta.Settings and Design:Prospective study in a tertiary care setup.Materials and Methods:A prospective study was conducted on pregnant females with high clinical risk of placenta accreta. Antenatal diagnosis was established based on CDUS and MRI. The imaging findings were compared with final diagnosis at the time of delivery and/or pathologic examination.Statistical Analysis Used:The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated for both CDUS and MRI. The sensitivity and specificity values of USG and MRI were compared by the McNemar test.Results:Thirty patients at risk of placenta accreta underwent both CDUS and MRI. Eight cases of placenta accreta were identified (3 vera, 4 increta, and 1 percreta). All patients had history of previous cesarean section. Placenta previa was present in seven out of eight patients. USG correctly identified the presence of placenta accreta in seven out of eight patients (87.5% sensitivity) and the absence of placenta accreta in 19 out of 22 patients (86.4% specificity). MRI correctly identified the presence of placenta accreta in 6 out of 8 patients (75.0% sensitivity) and absence of placenta accreta in 17 out of 22 patients (77.3% specificity). There were no statistical differences in sensitivity (P = 1.00) and specificity (P = 0.687) between USG and MRI.Conclusions:Both USG and MRI have fairly good sensitivity for prenatal diagnosis of placenta accreta; however, specificity does not appear to be as good as reported in other studies. Both modalities have complimentary role and in cases of inconclusive findings with one imaging modality, the other modality may be useful for obtaining the diagnosis. CDUS remains the first primary modality for antenatal diagnosis of placenta accreta, with MRI reserved for cases where USG is inconclusive.

Comparison of ultrasound and magnetic resonance imaging in the prenatal diagnosis of Apert syndrome: report of a case

The birth prevalence of Apert syndrome is estimated at 1:64,500 and accounts for about 4.5 % of all craniosynostosis with a male/female ratio equal to 1:1. It is associated to allelic mutations in the fibroblast growth factor receptor 2 (FGFR2) gene. Majority cases are sporadic. Prenatal ultrasound diagnosis is based on the detection of abnormal cranial shape, midfacial hypoplasia and bilateral syndactyly of hands and feet, hypertelorism, and exorbitism. Other abnormalities includes central nervous system anomalies, congenital heart diseases, cleft palate, and urogenital diseases. A 37-year-old Caucasian woman, gravida 2, para 1, was referred to our center of Prenatal Diagnosis for routine ultrasound at 21 weeks of gestation. We detected irregular head shape, dolicocephaly, prominent forehead, bilateral mild ventriculomegaly, suspicion of partial agenesis of the corpus callosum, hypertelorism, and midfacial hypoplasia, with a depressed nasal bridge and syndactyly, prompting a suspicion for Apert syndrome. Magnetic resonance excluded agenesis of corpus callosum and confirmed bilateral mild ventriculomegaly. A follow-up ultrasound, performed at 23 weeks, confirmed the anomalies showed in the previous scan. An amniocentesis was performed. The results showed a normal male karyotype, while the molecular genetic test confirmed a mutation in FGFR2 gene. Fetus macroscopic analysis showed compatible features. Our case underlines the complementary role of ultrasound and magnetic resonance imaging in the early prenatal diagnosis of Apert syndrome.

Ultrasound and magnetic resonance imaging in prenatal diagnosis of sacrococcygeal teratoma: Case report

Fetal tumors are relatively rare and the early prenatal diagnosis enables the prediction of possible complications and decision for appropriate treatment. This paper deals with the role of ultrasonography and magnetic resonance imaging in the early prenatal diagnosis of sacrococcygeal teratoma. A 21-year-old primigravida was found to have a large sacrococcygeal tumor measuring 25 x 30mm, presented mainly as a solid mass, when she underwent the initial ultrasound examination on the first day of 19th week of gestation. There were no other associated anomalies. The second ultrasound examination was obtained after 6 days and revealed that the tumor had doubled its size. The prominent enlargement raised suspicion of immature sacrococcygeal teratoma and thus, fetal magnetic resonance imaging was performed in the 20th gestation week. The examination showed a crococcygeal teratoma presented as a large solid mass with small microcystic areas, the largest diameter being 60mm, completely externally positioned with no intra-pelvic extension. Rapid tumor growth posed a threat to the fetal circulation and it was the main reason when opting for the termination of pregnancy at 20 weeks of gestation. Pathohystological examination confirmed the diagnosis of immature sacrococcygeal teratoma. In the prenatal period the magnetic resonance imaging of a fetal tumor initially diagnosed by ultrasound examination is an additional part of diagnostic procedure, and it is not contraindicated during pregnancy. Magnetic resonance imaging improves the delineation of the tumor. The prompt prenatal diagnosis of sacrococcygeal teratoma, as well as the detection of possible associated anomalies, is important for the pregnancy management, prediction of possible complications and choice of appropriate treatment. Ultrasonography and magnetic resonance imaging are noninvasive, compatible and complementary diagnostic modalities in evaluation of sacrococcygeal teratoma in prenatal period.

Limitations of fetal ultrasonography and magnetic resonance imaging in prenatal diagnosis of congenital cerebral arteriovenous malformations with hemorrhagic onset

A fetus at 30 gestational weeks was observed on fetal ultrasonography to have a dilated right lateral ventricle. After delivery, the entity was diagnosed as a prenatal intracerebral hemorrhage (ICH) due to a ruptured arteriovenous malformation (AVM). Ultrasonography and MRI examinations performed before birth indicated a cerebral aneurysm in the territory of the right middle cerebral artery. However, digital subtraction angiography revealed an intracystic hemorrhage due to a ruptured cerebral AVM. Arteriovenous malformations in children are rare, difficult to diagnose, and result in permanent sequelae after delayed treatment. Patient prognosis depends on early and accurate diagnosis and intervention. Outcomes can be improved if an AVM in a child is detected at the onset of ICH for young infants in the prenatal or early postnatal periods. Early AVM diagnosis is limited to fetal ultrasonography and MRI, and special consideration through invasive examination including neonatal digital subtraction angiography is urged unless a correct and clear diagnosis is made at an early stage. Prenatal ICH due to an AVM is rare. The authors discuss their observations and findings.

Ultrasonography and magnetic resonance imaging in prenatal diagnosis of tumour of the foetal head and neck

Foetal tumours are relatively rare; prenatal diagnosis enables additional diagnostics, and thus the decision on the continuation of pregnancy and planning of delivery. The paper presents prenatal ultrasound diagnostics of foetal head tumour with additionally analyzed magnetic resonance imaging (MRI). On ultrasound imaging, in a 27-year-old nullipara, a tumour of the foetal head was suspected at the 22nd gestational week. By consultative ultrasound, a 45 x 41 x 50 mm echogenic soft tissue tumour with hypoechogenic areas was confirmed, which originated from the left side of the skull spreading towards the neck on the left behind the ear. On colour Doppler no vascularisation was seen within the tumour but several vessels were seen along the border-line and on the surface. The scan showed no associated abnormalities. Karyotype was 46, XY. MRI scan using triplanar SSFSE and HASTE sequences was done at 26 weeks and confirmed a 84 x 45 x 71 mm tumour originating from the scalp, spreading along the endocranium over the entire surface of the fronto-temporal sqama and left parietal bone. The tumour did not disturb the integrity of the internal tabula, and did not spread intracranially. Based on these findings, the diagnosis of haemangioma was made. At 38 weeks gestation, a 3810 g male infant was delivered by Caesarean section. A bluish, well-defined, non-pulsatile tumour arising from the left frontoparietal region was seen, thus confirming the diagnosis of haemangioma. MRI improved delineation of the tumour facilitating better planning of postnatal management and mode of delivery, with the information on the postnatal course and prognosis. In the prenatal period, MRI following an ultrasound diagnosed foetal tumour, is an additional part of diagnostic examinations, and is not contraindicated during pregnancy.

Clinical significances of magnetic resonance imaging in prenatal diagnosis of vasa previa in a woman with bilobed placentas

We report a case of a pregnant woman diagnosed as having vasa previa by magnetic resonance imaging (MRI). A parous woman was referred to our hospital at 31 weeks of gestation due to suspicion of placenta previa. Transvaginal ultrasound examination together with the Doppler techniques showed a fetal vessel on a lesion of low and high mixed echogenecities over the internal os, but could not confirm whether it was placental tissue or not. MRI demonstrated that it was not placenta but a hemorrhage between bilobed placentas and that the vessel was running over the internal os freely from the placenta. At 34 weeks of gestation, emergency cesarean section was performed due to increasing vaginal bleeding. MRI should be useful in the diagnosis of vasa previa when the relation between the position of the placenta and that of suspicious vessels cannot be adequately evaluated by ultrasound.

OC19: Ultrasound versus magnetic resonance imaging in prenatal diagnosis of fetal malformations

OC19: Ultrasound versus magnetic resonance imaging in prenatal diagnosis of fetal malformations

Contribution of ultrafast magnetic resonance imaging in prenatal diagnosis of sonographically undetected cerebral tuberous sclerosis associated with cardiac rhabdomyomas

Contribution of ultrafast magnetic resonance imaging in prenatal diagnosis of sonographically undetected cerebral tuberous sclerosis associated with cardiac rhabdomyomas

Magnetic Resonance Imaging in Prenatal Diagnosis of Dacryocystocele

The presence of cystic dilation of the lacrimal drainage system (dacryocystocele) in the fetus must be differentiated from less benign paraocular masses. Three cases of dacryocystocele studied during fetal life by ultrasound and magnetic resonance (MR) imaging are reported. The accuracy of prenatal MR imaging facilitated a definite diagnosis depicting the characteristic triad of dacryocystocele: paraocular cystic mass in the medial canthus region, nasolacrimal duct enlargement, and intranasal cyst.

P098: Magnetic resonance imaging in prenatal diagnosis

P098: Magnetic resonance imaging in prenatal diagnosis

Initial experience using magnetic resonance imaging in prenatal diagnosis of osteogenesis imperfecta type II: A case report

We report a fetus with osteogenesis imperfecta (OI) first diagnosed by ultrasound in routine prenatal examination and further evaluated by magnetic resonance imaging (MRI). Fetal MRI was undertaken with a 1.5-T magnet using a body-phased array coil and an ultrafast imaging technique, half-Fourier single-shot turbo spin-echo (HASTE). Radiological examination shortly after birth and postmortem examination confirmed the prenatal diagnosis. In this case, fetal MRI provided excellent spatial and tissue resolution with multiplanar display. It revealed additional diagnostic information and improved imaging conspicuity. MRI complemented sonography for further differentiating clinical and sonographic findings.

Fetal magnetic resonance imaging in prenatal diagnosis of central nervous system abnormalities: 3-year experience

Fetal magnetic resonance imaging in prenatal diagnosis of central nervous system abnormalities: 3-year experience

Fetal magnetic resonance imaging in prenatal diagnosis of central nervous system abnormalities: 3-year experience

Objective: To evaluate the comparative merits of ultrasound and fetal magnetic resonance imaging (MRI) in the correct antenatal diagnosis of suspected central nervous system abnormalities.Methods:A retrospective review of 27 consecutive pregnancies referred for fetal MRI for suspected central nervous system abnormalities between July 1998 and July 2001. Women were referred for the MRI examinationwhen further anatomical and/or pathological clarification of the ultrasound scan findings was needed. Antenatal ultrasound scan and MRI were reviewed in relation to the findings on postpartum investigations.Results: Data were complete for 26 pregnancies. The median gestational age at the time of the ultrasound examination was 26 weeks (95% CI 24 weeks 2 days to 28 weeks 1 day). The median gestationalage at the time of magnetic resonance imaging was 27 weeks' gestation (95% CI 26 weeks 1 day to 29 weeks 2 days). Eight fetuses had associated skeletal, renal and/or cardiac abnormalities previously notedon ultrasound examination. MRI confirmed the ultrasound diagnosis in 15/26 cases (58%). It changed the diagnosis to the correct one in 7/26 (27%) and misdiagnosed four cases (15%). Three of the four casesthat were misdiagnosed on MRI occurred in the first 18 months of our 36-month experience.Conclusion: Ultrasound remains the primary imaging modality for prenatal diagnosis. Fetal MRI appearsto be a useful adjunct to ultrasound to confirm or exclude certain abnormalities; this will consequently help in the counselling of parents and assist in planning further management. However, like any imagingtechnique, the sensitivity and specificity of the test are likely to improve with experience.

Magnetic resonance imaging in prenatal diagnosis.

Ultrasound is the screening modality of choice for fetal imaging. However, when additional information regarding fetal anatomy or pathology is needed, fast magnetic resonance (MR) imaging is being used increasingly as a correlative imaging modality because it uses no ionizing radiation, provides excellent soft tissue contrast, has multiple planes for reconstruction, and a large field of view. Sonographic examination of the fetus is still important for selecting the appropriate fetuses for MR examination and to guide the protocol of the examination. Performance of high quality sonographic and MR examinations, as well as interpretation by individuals familiar with prenatal diagnosis, are important factors for optimal parental counseling. Magnetic resonance imaging frequently adds additional information beyond that available with ultrasound. This information commonly changes patient counseling, and at times patient management.