Resin Infiltration Research Articles

Repeated Etching Cycles of Resin Infiltration up to Nine Cycles on Demineralized Enamel: Surface Roughness and Esthetic Outcomes-In Vitro Study.

Resin infiltration (RI) is used to mask enamel opacities. There are three recommended etching cycles. However, anecdotal evidence suggests that favorable esthetics outcomes can be obtained by increasing the etching cycles. This study aimed to evaluate the effects of repeated etching cycles during RI application on esthetic changes and surface roughness of demineralized enamel at multiple treatment stages. Artificial demineralization was prepared on the buccal surface of ninety sound extracted premolars. The teeth were divided into nine groups (n = 10); with each consecutive group having one additional etching cycle up to nine etching cycles. Resin infiltrant was performed twice, first for 3 min (Resin 1) and again for 1 min (Resin 2). Surface roughness and esthetic changes were assessed using a profilometer (Ambios XP-200) and Minolta spectrophotometer, respectively, at baseline (sound enamel), etching, resin 1, resin 2, 7 days, and 28 days post resin applications. Data were analyzed with two-way ANOVA (p < 0.05). There was a significant interaction between the different stages and various groups of etching cycles on surface roughness, F(48, 126) = 3.48, p < 0.001. There was a significant interaction between the different stages and various groups of etching cycles on color changes, F(4, 126) = 1.177, p = 0.045. The surface roughness of demineralized enamel infiltrated with RI was less than that of sound enamel (baseline). There is a significant difference in color changes between resin 1 and resin 2 (p < 0.05). After five etching cycles, RI improved the esthetic of the color of teeth similar to the baseline. Surface roughness and color changes remained constant for 28 days. RI can be considered an effective and predictable treatment option for the restoration of early enamel lesions owing to its better surface characteristics and reliable masking effects. The color stability and surface roughness stay unaltered for up to 28 days.

PRESENTATION AND MANAGEMENT OF DENTAL FLUOROSIS IN A RESOURCE LIMITED FACILITY.

Background: Dental fluorosis is a developmental disturbance characterized by excess fluoride in hard tissues of the teeth. The appearance of teeth affected by dental fluorosis may negatively affect individual self-esteem and overall quality of life. Thus, the need for treatment, though there is still debate on the best treatment modalities. The objective of this study was to document the presentation and management of dental fluorosis in a resource limited facility in north central Nigeria.&#x0D; Methods: A cross-sectional hospital-based study conducted among out-patients attending a secondary oral health care facility in Jos, north central Nigeria between June 2020 and June 2022. Sociodemographic characteristics were recorded. All patients were examined for presence of dental fluorosis. Dean’s Index was used to classify dental fluorosis. Patients with dental fluorosis who consented to the study were treated. Treatment modalities included oral prophylactic treatment, microabraision and resin infiltration. Data analysis was by the use of Statistical Package for Social Sciences (SPSS) version 23.0 A p-value of &lt; 0.5 was taken as statistically significant.&#x0D; Results: During the study period, 1201 patients presented with different oral health challenges. Among these 200 (16.7%) were diagnosed of dental fluorosis. The mean of the patients with dental fluorosis was 14.15 ± 1.91 years. Nearly half 98(49.0%) of the patients who presented with dental fluorosis were children, 65(32.5%) were teenagers and 37(18.5%) were young adults (p=0.037). Among the patients, 123 (61.5%) were females. The moderate type of dental fluorosis 75(37.5%) was the commonest type of dental fluorosis seen. Out of the 200 patients with dental fluorosis, dental caries was present among 55(37.5%) patients. 185(92.5%) requested for treatment. 231 intervention procedures were undertaken on different classes of dental fluorosis.&#x0D; Conclusion: Dental fluorosis is prevalent among the dental out-patients seen at the study center during the study period. More patients presented with moderate class of dental fluorosis. Presentation was more among children and teenagers below 20 years. More female presented and requested for intervention than the males. Resin infiltration was found to be cost effective at this facility.&#x0D;

A facile method for rejuvenating the bonding efficacy of root canal sealer-smeared dentine

ObjectivesTo examine the efficacy of glycine powder air-polishing on cleaning root canal sealer-smeared dentine. MethodsDentine surfaces were contaminated with a smear of epoxy resin-based sealer or tricalcium silicate-based sealer. The contaminated surfaces were cleaned with saline, 75% ethanol, or air-polishing with glycine powder. Uncontaminated dentine was used as the control. The cleanliness of pulpal floor dentine was examined using scanning electron microscopy and energy dispersive X-ray analysis. The effectiveness of the three cleaning protocols was examined by testing the tensile bond strength of a self-etching adhesive to the decontaminated dentine. Resin infiltration into the dentinal tubules was identified using confocal laser scanning microscopy (CLSM). ResultsMorphological examination and elemental analysis indicated that glycine powder air-polishing was more effective in removing the two sealers. Tensile bond strength of adhesive-bonded dentine was significantly reduced when either sealer was cleaned with saline or ethanol. Conversely, air-polishing restored the adhesive strength of the sealer-smeared dentine to the level of the control. Longer and denser resin tags were identified with CLSM when sealers were removed with air-polishing. ConclusionsAir-polishing with glycine powder was effective in cleaning sealer-smeared dentine, as demonstrated by the rejuvenation of the tensile bond strength of a self-etching adhesive to the decontaminated dentine. Clinical significanceGlycine powder air-polishing improves the cleanliness of root canal sealer-smeared dentine and rejuvenates adhesive bonding effectiveness.

BASIC DIRECTIONS IN FLUOROSIS TREATMENT

The territory of Poltava region belongs to the Buchatsky hydrogeological province, whose groundwater is characterized by an elevated fluorine level content. The cause of endemic dental fluorosis particularly in the children’s population of the region is water consumption with surplus concentration of this chemical element. Also, having fluorosis a condition that develops from a high fluoride concentration in drinking water- causes disorder of hard tooth tissues maturing, mineralizationand teeth germ development. This, in turn, has a negative influence on enamel amelogenin synthesis and violation of the crystals maturing, determines a surface porosity. The chalky spots, brown pigmentation, and enamel erosion destruction lesions are characterized the different severity manifestation of the fluorosis.&#x0D; The purpose of our research was to conduct a thorough analysis of all the material we found on this topic, gather all possible information on new trends in recent years in the treatment of dental fluorosis: what are the methods, their origins, indications for use, clinical stages and advantages.&#x0D; Dental enamel fluorosis requires different approaches to treatment depending on the severity of clinical manifestations. Obviously, as the leading method is remineralizing therapy. One of the method is offered by Nikolishina E.V. etc. [6], which is carried out in the following way: after carry out of the professional hygiene procedure, next step, individual caps were made of transparent silicone filled with 10% solution «Poltavsky Bishofit» and applied on the fluorosis teeth, daily course consist with 30 minutes and 10-20 procedures.&#x0D; Enamel microabrasion is the first minimally invasive treatment method of mild and moderate dental fluorosis using to removes opaque brown spots and surface roughness smoothing, providing a flat and shinier surface. The microabrasion technique involves etching with mild acid in combination with application of abrasive components. Resin infiltration has also become a popular treating dental fluorosis technique without loss of hard tissue.&#x0D; Resin infiltration is based on the application of hydrochloric acid to the hard tissues of the tooth and subsequent coating with a low-viscosity resin that penetrates into the microspaces of the tooth enamel. The cloaking effect is based on the refractive index. The optical properties of the affected enamel change and it looks like a healthy enamel surrounding. The indication to dental fluorosis treatment of severity forms in permanent teeth with mature roots is restoration of teeth, veneers, orthopedic crowns, if the microabrasive method hasn’t aesthetic effect efficiency.&#x0D; Thus, in cases of aesthetic changes due to fluorosis, minimally invasive restorative approaches that preserve dental hard tissue such as microabrasion method, external bleaching or resin infiltration should be considered before invasive restorative procedures. More invasive treatments may be considered if the results remain unsatisfactory.

Dilemmas and Opportunities in Dentistry in the Face of the Covid-19 Pandemic

On March 21, 2020, the "Janta Curfew" was enforced in India and extended in three parts, restricting all movement. Due to the lack of physical medical services available during that time, the suffering of people with various oral conditions increased. There was an essential lag in this face-toface treatment during the lockdown, and the dental treatment of children declined the most among all age groups. The altered stress-related sleep patterns in younger children led parents to use faulty methods to promote sleep more frequently, such as bottle-feeding children with fermentable liquids like milk rather than honey or sugar-laden pacifiers. These actions increased their vulnerability to developing early childhood caries (ECC). The COVID-19 pandemic provides a reason for dentistry to move from a surgical intervention-based approach to that emphasising prevention and associated with the decreased aerosol generation, such as selective carious tissue excavation, sealants, resin infiltration, Silver Diamine Fluoride (SDF) application, and Hall technique. The current scenario should also prompt the researchers to do additional research applying the pandemic "shock" to dentistry to systematically explore how treatment delays affect dental health and overall well-being.

Evaluation of Color Changes in Resin Infiltrated White Spot Lesion after Exposure to Different Colored Oral Rinses

Evaluation of Color Changes in Resin Infiltrated White Spot Lesion after Exposure to Different Colored Oral Rinses

Bonding of chitosan and nanochitosan modified universal adhesive to dentin

ObjectivesTo evaluate Wettability, pH and Microtensile bond strength (immediate and after thermocycling) of a universal adhesive after incorporation of 0.5% and 1% bulk-chitosan or nanochitosan. MethodsAll-bond universal adhesive was used to obtain five groups according to the type of additive; CONTROL, CHITOSAN (0.5), CHITOSAN (1%), NANOCHITOSAN (0.5%) and NANOCHITOSAN (1%). Contact angle and pH of the adhesives were tested with n = 7 for each test. for Microtensile bond strength testing, premolars teeth (N = 50) were used; twenty-five teeth for immediate bond strength and the other twenty-five were tested after thermocycling. ResultsCONTROL and CHITOSAN (0.5%) groups showed significantly higher contact angle measurements (30.78 ± 3.71 and 27.77 ± 4.63 respectively) compared to all other groups. CONTROL group showed significantly higher pH value (3.17 ± 0.05), followed by NANOCHITOSAN (0.5%) and NANOCHITOSAN (1%) and the least pH values were for 0.5% CHITOSAN group and CHITOSAN (1%). Bond strength results revealed that NANOCHITOSAN (0.5%) and NANOCHITOSAN (1%) had the highest bond strength (52.99 ± 16.14, 55.80 ± 16.11). CONTROL, CHITOSAN (0.5%) and CHITOSAN (1%) had no significant difference. After thermocycling, NANOCHITOSAN (0.5%) and NANOCHITOSAN (1%) had the highest bond strength values (38.58 ± 7.01 and 40.07 ± 11.40), followed by CHITOSAN (0.5%) and CHITOSAN (1%), and the least bond strength value was obtained by the control group. Hybrid layer micrographs showed that NANOCHITOSAN (1%) has intense resin infiltration before and after aging compared to all other groups. ConclusionIncorporation of nanochitosan (0.5% and 1%) improved the universal adhesive microtensile bond strength and bond durability.

Typical esthetic outcomes using 5 different modalities to treat MIH affected teeth: a case series

Introduction: therapeutic options for incisors affected by Molar Incisor Hypomineralization range from very conservative procedures to those considered to be more invasive. Clinicians must select the appropriate approach, considering the outcomes of the procedures. Methods: this case series presents clinical outcomes of five female patients with aesthetic complaints associated with the Molar Incisor Hipomineralization. Results: macroabrasion, microabrasion and dental vital bleaching were used as combination techniques in three cases. Resin infiltration was indicated for a specific case, considering the oncoming orthodontic treatment. Composite restoration was performed in one patient with posteruptive enamel breakdown. Conclusions: clinicians must select the appropriate approach according to an individualized evaluation of each case, considering factors such as the patient's expectations, dental age, psychosocial period, the severity of the condition, presence of sensitivity and the presumed aesthetic result of the selected treatment. The advantages and disadvantages of the techniques are presented.

Comparison of therapies of white spot lesions: a systematic review and network meta-analysis

ObjectiveWhite spot lesions (WSLs), the earliest evidence of enamel demineralization, are considered amenable to intervention to achieve a remineralized or arrested state of caries. The management of WSLs is quite challenging, and there is no definitive cure as yet. We performed a network meta-analysis to assess the efficacy of seven therapies for WSLs and gave a hierarchy of them.Materials and methodsWe systematically searched the PubMed, EMBASE, Cochrane, and Web of Science databases (last search: July 2022) to identify all relevant studies. We limited our search to studies published in English. Randomized controlled designed in vitro/clinical trials related to the efficacy of the seven therapies for WSLs were included. Data extraction was performed independently by two reviewers. The risk of bias (ROB) 2.0 tool from Cochrane and a previous in vitro methodological tool will be used for the quality assessment. Variations in quantitative light-induced fluorescence (QLF), laser fluorescence (LF), and lesions area were the primary outcome measures. Standard mean difference (SMD) was used as the effect size for the Network meta-analysis (NMA). Consistency and inconsistency tests were conducted. The hierarchy of 7 treatment effects was evaluated using surface probabilities under cumulative ranking (SUCRA). Publication bias was evaluated using a bias plot.ResultsForty-two articles were included in the systematic review. Thirty-one of them, with a total of 1906 participants, were included in the network meta-analysis. The studies owned a low and moderate risk of bias. This analysis does not suffer from significant inconsistency. The difference between 4 groups ‘self-assembled peptide (SAP) P11-4’, ‘P11-4 + Fluoride Varnish (FV)’, ‘Resin Infiltration (RI)’, ‘casein phosphor peptides-amorphous calcium fluoride phosphate (CPP-ACFP)’ and the 'Control' group was found to be statistically significant. Compared to the ‘FV’ and ‘casein phosphor peptides-amorphous calcium phosphate (CPP-ACP)’ groups, the ‘P11-4 + FV” group and ‘RI” group made a significant difference. The hierarchy was evident in the SUCRA values of 7 therapies. P11-4 + FV and RI were considered effective therapies compared to the control group or the FV group (gold standard group).ConclusionsThe available evidence suggests that resin infiltration and P11-4 in combination with fluoride varnish had advantages over gold standard (FV). The effect of tricalcium phosphate-based drugs and fluoride is not very noticeable. Overall, drugs based on P11-4 and resin infiltration will be better therapies. Using more than two drugs in combination also would increase efficacy.

Aesthetic Conservative Management of Fluorosis Affected Teeth with Resin Infiltration: Case Report

Aims: The scientific case report aims to show recent technique of minimally invasive procedure for aesthetic resolution in moderate to severe fluorosis affected teeth.&#x0D; Presentation of Case: A clinical case of severe fluorosis was treated with microabrasion followed by resin infiltration. A commercial resin was applied on the facial surfaces of the anterior teeth resulting in masking of spots and re-establishing color uniformity.&#x0D; Discussion: The procedure proved to be a good option to mask spots associated with moderate to severe fluorosis. Moreover, it is a relatively quick, inexpensive and minimally invasive treatment.&#x0D; Conclusion: This case report demonstrates that the microabrasion and resin infiltration technique is an effective conservative aesthetic treatment. It minimizes an individual’s tooth discoloration when diagnosed with moderate to severe levels of dental fluorosis and has shown a good outcome even after twelve months.

Minimally invasive technique for improvement of aesthetic in cases of mild to moderate fluorosis: A case report

Patients have been increasingly worried about tooth discolouration in recent years, particularly when the maxillary anterior teeth are implicated. Dental fluorosis appears clinically as white patches or opaque white lines, or the tooth surface may have a white, parchment-like look. The brown stains visible in moderate to severe fluorosis are caused by the ingestion of extrinsic stains, primarily from the food. Higher fluoride concentrations cause discontiguous or confluent pitting of the enamel surface, which is accompanied by extrinsic stains.The aim of this case report is to demonstrate a conservative technique of minimally invasive procedures for esthetic correction in anterior teeth which includes methods like microabrasion, tooth bleaching and resin infiltration carried out in sequence for the removal or masking of fluorosis stains in maxillary and mandibular anteriors.

Effectiveness of Phytic Acid as an Etchant in Dentistry: A Systematic Review

AbstractThe aim of this study was to assess the effect of phytic acid and to compare it with the phosphoric acid etching through a systematic review. systematic search was carried out using PubMed/MEDLINE, Cochrane library, Indmed, Scopus, and Liliacs databases conducted upto January 2022. In vitro studies comparing phytic acid and phosphoric acid as an etchant on tooth surfaces that performed bond strength, smear layer removal, collagen degradation and monomer penetration were included. The risk of bias was assessed considering Checklist for Reporting In-vitro Studies guidelines. Five studies were chosen for full-text assessment out of 830 that were potentially eligible. The studies found that phytic acid improved bond strength, collagen degradation, smear layer removal, and monomer penetration. Every study had a moderate-to-high risk of bias. Phytic acid enhanced the etch and rinse adhesive's binding strength to dentin, effectively eradicated the smear layer, protected dentin collagen from degradation, and had better resin infiltration and minimal effect on pulpal cells.

RESIN INFILTRATION FOR MINIMALLY INVASIVE TREATMENT OF INITIAL CARIES AND NON-CARIOUS SPOT LESIONS: LITERATURE REVIEW

A concept of minimal intervention dentistry focuses on dental caries prevention, managing risk factors, detection of initial caries lesions and minimally invasive treatment. The article presents the possibilities, indications and advantages of Icon resin infiltration in the treatment of initial dental caries and non-carious spot lesions. Based on data from previous studies it is effective, painless and aesthetic method. After resin infiltration of enamel lesions the integrity of the tooth is preserved, the restoration of luster, transparency and color of the enamel is observed, the microhardness and surface roughness of the demineralized area increased to the values of intact dental tissues. Icon infiltration can be used for the treatment of initial non-cavitated dental caries on proximal and smooth surfaces of teeth as well as for the aesthetic treatment of non-carious spot lesions.

Long-Term Chromatic Durability of White Spot Lesions through Employment of Infiltration Resin Treatment.

Background and Objectives: White spot lesions (WSLs) denote regions of subsurface demineralization on the enamel that manifest as opaque and milky-white regions. Treatment for WSLs is essential for both clinical and aesthetic reasons. Resin infiltration has been identified as the most efficacious solution for alleviating WSLs, but studies with long-term monitoring are scarce. The aim of this clinical study is to assess the color change stability of the lesion after four years of implementing the resin infiltration technique. Materials and Methods: Forty non-cavity and unrestored white spot lesions (WSLs) were treated with the resin infiltration technique. The color of the WSLs and adjacent healthy enamel (SAE) was assessed using a spectrophotometer at T0 (baseline), T1 (after treatment), T2 (1 year after) and T3 (4 years after). The Wilcoxon test was utilized to determine the significance of the variation of color (ΔE) between WSLs and SAE over the observed time periods. Results: When comparing the color difference ΔE (WSLs-SAE) at T0-T1, the Wilcoxon test demonstarated a statistically significant difference (p < 0.05). For ΔE (WSLs-SAE) at T1-T2 and T1-T3, the color variation was not statistically significant (p = 0.305 and p = 0.337). Conclusions: The study's findings indicate that the resin infiltration technique is an effective solution for resolving the appearance of WSLs, and the results have demonstrated stability for a minimum of four years.

Electrically-assisted void reduction for synergistic improvement in strength and toughness of fiber-reinforced composites

In the pursuit of designing fiber-reinforced composites with synergistic increased strength and toughness, a novel electric field-driven resin infiltration method is proposed. Specifically, during epoxy resin solidification, the void content of the composites is effectively reduced by 77.1%, from 2.14% to 0.49%, and the tensile strength, interlaminar shear strength, and interlaminar fracture toughness of the composites increase from 539.9 MPa to 748.7 MPa (equivalent to 38.7%), from 40.9 MPa to 57.3 MPa (equivalent to 40.1%) and from 2.1 kJ/m2 to 3.0 kJ/m2 (equivalent to 42.9%) under the applied electric field, respectively. The improvement of the mechanical properties is primarily ascribed to the fact that the electric field-induced Maxwell force drives the liquid resin to flow into intra-tows and inter-tows, thereby improving the wettability of the resin to the fiber tows and correspondingly reducing the void content of the composite, which is supported by the finite element simulation of the rheological behavior of the resin. Interestingly, the application of an electric field can reduce the curing temperature of the composites by nearly 10 °C compared to the baseline composites, while maintaining the same mechanical properties. Therefore, it is an economical, and promising approach to fabricating composites with excellent mechanical properties.

The Role of Cellular Metabolism in Maintaining the Function of the Dentine-Pulp Complex: A Narrative Review.

The cellular metabolic processes ensure the physiological integrity of the dentine-pulp complex. Odontoblasts and odontoblast-like cells are responsible for the defence mechanisms in the form of tertiary dentine formation. In turn, the main defence reaction of the pulp is the development of inflammation, during which the metabolic and signalling pathways of the cells are significantly altered. The selected dental procedures, such as orthodontic treatment, resin infiltration, resin restorations or dental bleaching, can impact the cellular metabolism in the dental pulp. Among systemic metabolic diseases, diabetes mellitus causes the most consequences for the cellular metabolism of the dentine-pulp complex. Similarly, ageing processes present a proven effect on the metabolic functioning of the odontoblasts and the pulp cells. In the literature, several potential metabolic mediators demonstrating anti-inflammatory properties on inflamed dental pulp are mentioned. Moreover, the pulp stem cells exhibit the regenerative potential essential for maintaining the function of the dentine-pulp complex.

Management Of Clear Aligner-related Severe Enamel Demineralization With A Modified Resin Infiltration Technique

Introduction: Enamel demineralization expressed as white spot lesions (WSLs) has been reported to be associated with both fixed and removable orthodontic appliances. Case report: This case report described the management of a patient with clear aligner-related severe enamel demineralization using a modified resin infiltration technique. Microabrasion with Opalustre (Ultradent, Utah, USA) was performed to remove the remineralized enamel surface followed by repeated etching with ICON Etch (DMG, Hamburg, Germany) until the WSLs disappeared after ethanol application. A #12 blade could be used to check whether the superficial layer was demineralized enough for the resin to infiltrate. The ICON-Infiltrant (DMG, Hamburg, Germany) was applied to the etched enamel and light-cured. After treatment, all the WSLs showed improvement with the color nearly matching the adjacent sound enamel. Discussion: Modified resin infiltration technique combined with microabrasion could be an effective noninvasive method to treat severe enamel demineralization including shallow localized enamel breakdown. However, more clinical studies are required to assess the efficacy and safety of this method.

Application of laser on enamel surface with three types of bioactive glasses-based resin infiltrants: An in vitro study

ObjectiveThe study aimed to evaluate and compare the surface micro-hardness, roughness, color, and morphology of enamel after Er,Cr:YSGG laser irradiation, followed by application of three types of bioactive glasses-based resin infiltrants, and the samples groups were challenged with the pH cycle. MethodologyExperimental photoactivated resin infiltrants were synthesized using dimethacrylate resins, whereby three different types of bioactive glasses (BGs), i.e., 45S5, fluoridated-BG (F-BG), and borosilicate-BG (B-BG), were incorporated into the resin system. Initially, white spot lesions were created artificially on the toosth enamel surface, then irradiated with Er,Cr:YSGG laser. Then, the resin-only and BG-based resins were infiltrated on the enamel surface. All samples were pH challenged for 14 days, and the micro-hardness, surface roughness, surface morphology, and color stability (ΔE) analyses were conducted before and after the 14 days pH challenge. ResultsAfter laser irradiation, the micro-hardness was significantly high with 45S5 group compared to resin-only (p = 0.021), F-BG (p = 0.042), and B-BG (p = 0.001) groups. After the pH challenge, the micro-hardness values for all groups were reduced significantly (p ≤ 0.05). The surface roughness was least with the resin-only group and showed a non-significant difference with F-BG (p = 0.34) and significant differences with both B-BG (p = 0.005), and 45S5 (p = 0.010) groups. After the pH cycle, the roughness of all groups was increased significantly (p ≤ 0.05), except B-BG group showed a non-significant difference (p = 0.528). The B-BG group showed significantly high ΔE between day 0 and baseline compared to resin-only (p = 0.0008), F-BG (p = 0.017), and 45S5 (p = 0.029), whereas between day 14 and baseline, the lowest ΔE value was observed for B-BG (14.2 ± 2.10) and maximum for the resin-only (20.57 ± 2.47) group. The SEM images showed pitting on the surface of all resin infiltrant groups after 14 days of pH challenge. ConclusionThe morphological difference was observed after the laser irradiation on the enamel surface. The differences in micro-hardness, surface roughness, and color were observed after the application of experimental resin infiltrants and significant differences were observed after the pH challenge.

Roughness and Microhardness of Demineralized Enamel Treated with Resinous Infiltrants and Subjected to an Acid Challenge: An in vitro Study

Background: Resinous infiltrating has proven effective in arresting incipient caries lesions. Objective: This study aimed to assess the penetration depth of an experimental resin-infiltrant (75% - TEGDMA, 25% - Bis-EMA, 1% - EDAB, 0.5% camphorquinone), compare it with commercial infiltrant Icon®, and analyze the surface-roughness and microhardness of the resin-materials infiltrated into tooth specimens, before and after pH cycling. Methods: To assess penetration depth, sound third molar specimens were submitted to ten de-remineralization cycles for incipient carious lesion induction and were then randomly divided into 2 groups (n=3): (I) Experimental Infiltrant (EI) and (II) Commercial Infiltrant Icon (CI). After resin infiltration into specimens, qualitative Confocal Fluorescence Microscopy images were captured. For roughness and microhardness assessment, new specimens were demineralized, then randomly divided into two groups (n=20): (I) Experimental Infiltrant (EI) and (II) Commercial Infiltrant Icon (CI) and submitted to roughness and microhardness readouts at the following time-intervals: (T1) sound tooth, (T2) white-spot caries lesion, (T3) resin material that infiltrated, and (T4) resin material that infiltrated and was exposed to pH-cycling. In statistical analyses, generalized linear models of repeated measures in time were applied, with a significance level of 5%. Results: The experimental infiltrant penetrated the carious lesion and exhibited lower roughness values after its application, even after pH cycling, similar to the CI. The microhardness value of the EI group was significantly lower in the last three-time intervals evaluated compared to CI. Conclusion: Experimental resin infiltrant was efficient in penetrating white spot lesions and reducing surface roughness; however, it did not increase surface microhardness.

Management of Hypoplastic or Hypomineralized Defects with Resin Infiltration at Pediatric Ages: Systematic Review

Hypoplastic or hypomineralized enamel defects represent a recurrent reason for consultation within the pediatric population, causing great discomfort due to their aesthetic appearance, as well as their functional limitations. Current conservative dentistry requires minimally invasive treatments in order to treat such defects and provide successful, definitive solutions. A systematic review of the literature has been carried out in accordance with the PRISMA recommendations. A search was carried out in the PubMed, Scopus, SciELO and Web of Science databases, completed with a manual search. The following variables were extracted from the selected studies: author, year, publication journal, type of study, sample, age of the participants and the materials used for its development. From the initial electronic search of the four databases, 282 articles were identified: 34 from PubMed, 240 from Scopus, 0 from SciELO and 8 from Web of Science. After eliminating duplicate articles, a total of 225 remained. After reading the title and abstract, 158 articles were eliminated, leaving 68. Upon reading the full text, the remaining studies were eliminated for not answering the research question or the inclusion criteria, leaving a total of 13 articles. Finally, 12 articles were used to carry out the systematic review. Treatments performed to date with the ICON™ system in pediatric patients have shown good results after their application. Since the variability of diagnostic methods has been observed, new diagnostic and assessment protocols should be created after treatment to objectify their effect on hypoplastic or hypomineralized enamel defects. In the same way, it has been described that treatment provides better results if combined with other opalustre-type or remineralizing materials. This review is registered in PROSPERO with the number CRD42021288738.