Endangered species are being threatened by climate and land-use changes. However, the relative effects of climate and land-use changes on forest resident birds remain unclear. In this study, we employed an ecological niche model to forecast the potential influence of climate and land-use changes on Reeves’s pheasant (Syrmaticus reevesii), while taking into account topographical limitations. We observed that climate and land-use changes would have a remarkably negative impact on Syrmaticus reevesii, and climate change would play a dominant role. Consequently, the potential distribution range of Syrmaticus reevesii would sharply decrease, and this species may face a significant risk of extinction in 2070. In addition, we found that the area change predicted by climate and land-use changes would be significantly lower inside the China Nature Reserve Network (NNR) than outside the NNR. However, less than 15% of the area suitable for Syrmaticus reevesii has been covered by NNR. Furthermore, our results showed that the response of Syrmaticus reevesii to climate and land-use changes largely depended on topographical factors, and Syrmaticus reevesii would face greater impacts from climate and land-use changes under topographical limitations. Taken together, we highlight that it is imperative to adjust and develop nature reserve networks and conservation strategies to cope with rapid global environmental change.