Acupuncture Research Research Articles

Annual advances of acupuncture research in 2021

Annual advances of acupuncture research in 2021

거리 조각을 매개로 한 도시재생에 관한 연구- 조각의 Acupuncture와 Micro-implantation 개념 도입을 중심으로 -

The great development of urban built environment and the history of a city have been, historically, faced with such a dilemma at all times: intact protection of its history or urban renewal? Urban acupuncture provides another development strategy, trying to make the continuation of the original texture and the overall development of the city simultaneously. Urban acupuncture has no strict definition and universal standard model. It is a city development strategy with rich connotation and open denotation, and has quite a variety of interpretations and understandings. The idea of Manuel de Sola-Morales provides inspiration for this paper. Based on diverse literature from South Korea, Europe and China, street sculpture is found, from the perspective of culture and environment, to be used as urban catalyst to catalyze the regional development potential and influence urban regeneration. Through the research, we can find that the focus of the research and practice of urban regeneration and urban acupuncture from the perspective of environment is still the transformation of buildings and regions, the upgrading of public infrastructure, the optimization of public space and road traffic; the focus of the research and practice of urban regeneration and urban acupuncture from the perspective of culture is also very important Macro, mainly urban design. Therefore, this study boldly combines the urban acupuncture with the sculpture standing in the street, and advocates that the key acupoints of the street should be selected through sculpture for small-scale intervention or micro implantation. This paper attempts to refine the concepts of Acupuncture of sculpture and micro implantation of sculpture under the framework of urban regeneration. At the same time, it also tries to point out the new direction of urban regeneration. At the same time, it also provides some reference for the practice of urban regeneration.

Quotation Accuracy of Systematic Review and Meta-Analysis Protocols on Acupuncture.

Currently, published systematic review protocols (SR protocols) have increasingly become a new trend in fields such as acupuncture and are therefore a new source of quotations in these fields. Systematic reviews are considered the pinnacle of the evidence pyramid as they embody comprehensive literature searching. Quotations are key elements to achieve this goal as they can support the assertions of the original authors, but the ‘misquotation’ exists, too, and they can be misleading to the reader. The aim of this study was to examine the quotation accuracy of SR protocols in a meta-analysis on acupuncture research. We searched SCOPUS through 31 December, 2020, and each protocol and its citations were analyzed and classified as correct or incorrect. We used descriptive statistics to report the quotation errors and characteristics of the included protocols. The results showed 248 SR protocols, where 124 protocols received quotations and 38 quotations (31.4%) were erroneous. Only 11 (4.4%) of the published SRs and SR protocols had been published previously. Furthermore, the scientific journal in which the most SR protocols were published was Medicine (193; 77.8%), followed by BMJ Open (39; 15.7%). Authors from China (86.5%) were the most productive in publishing SRs and SR protocols. Finally, we concluded that the number of SR protocols and meta-analyses published in scientific journals and indexed by databases exceeds the publication capacity of the SRs associated with them, generating scientific literature that does not make any novel contribution to knowledge.

Acupuncture – a national heritage of China to the world: international clinical research advances from the past decade

Abstract Acupuncture originated in China and is an important component of traditional Chinese medicine. The elucidation of its anesthetic mechanisms, the medical needs of Western societies, as well as the proven therapeutic effects of this technique have made it the most widely used medical practice in the world. The concept of evidence-based medicine has been introduced in acupuncture research for technical improvement and the production of high-quality clinical evidence. Upon reviewing the acupuncture clinical research over the past 10 years, we found the gradually increasing range of diseases that it benefits, from pain management to neoplasms and genitourinary, digestive, and mental disorders. Acupuncture is included in a number of international guidelines for clinical practice. However, high-quality clinical evidence to support the efficacy and effectiveness of acupuncture is lacking as a result of multiple exceptional clinical trials conducted by Western researchers that have yielded antagonistic results. Future clinical research should focus on exploring objective evaluation methods for studying the therapeutic effects of acupuncture.

Effects of LI11 Acupuncture on CO2 reactivity in the anterior and middle cerebral arteries during hyperventilation-induced hypocapnia in normal subjects: A before and after study

Objectives: The LI11 (Quchi) acupuncture point has always been included in the Seven acupoints for stroke; however, additional LI11 acupuncture research is needed. In this study, the effect of LI11 acupuncture on cerebral blood flow of the anterior cerebral arteries (ACA) and middle cerebral arteries (MCA) was investigated.Method: This study included 10 healthy young male subjects. Cerebral blood flow velocity and cerebrovascular reactivity were measured using transcranial Doppler sonography. Changes in hyperventilation-induced carbon dioxide (CO2) reactivity and modified ACA and MCA blood flow velocity at 40 mmHg (CV40), blood pressure, and heart rate were observed before and after LI11 acupuncture treatment.Results: A statistically significant increase in contralateral anterior cerebral artery CO2 reactivity (p=0.036) and decrease in contralateral middle cerebral artery CV40 (p=0.047) were observed. No significant difference in mean blood pressure was shown. A statistically significant increase in heart rate occurred after LI11 acupuncture; however, it was not clinically significant as there were negligible changes in the heart rhythm.Conclusions: LI11 acupuncture treatment could improve cerebral blood flow velocity. These results might be explained by regulating endothelium-dependent vessel dilation in the anterior cerebral artery region.Trial registration: This trial has been registered with Clinical Research Information Service, a service of the Korea Centers for Disease Control and Prevention: KCT0004494 (retrospectively registered). https://cris.nih.go.kr/cris/search/search_result_st01.jsp?seq=15359

Randomized controlled trials of acupuncture and moxibustion in China in past 45-year (1975-2019): hotspots and trends

By searching the randomized controlled trials (RCTs) of acupuncture and moxibustion from CNKI since its inception date to december 31 of 2019, the development status and hot trend of RCTs of acupuncture and moxibustion in China were summarized. The CiteSpace and VOSviewer software were used to perform keyword co-occurrence analysis, clustering analysis, time-zone analysis and citation-burst analysis, and visual map was drawn. As a result, a total of 60 995 articles were included, which were published in 1027 academic journals with 1787 keywords. The publication date was from 1975 to 2019. During the past 45 years, the publications of RCTs on acupuncture and moxibustion had shown an overall growth trend with characteristics of the times. The RCTs of manual acupuncture ranked the top, and its proportion of publications every 5 years was stable in the past 30 years. Since 1994, the hot words such as electroacupuncture, warming needling, auricular point sticking and various acupoint therapies had emerged; meanwhile, the spectrum of diseases had broadened, and an evolutionary trend corresponding to therapies and disease systems had been formed. In recent decade, the RCTs using moxibustion therapy have increased significantly, and the hot words such as "sub-health" "winter diseases being treated in summer" and "acupoint application/ moxibustion during the dog days" had indicated that acupuncture clinical research was further inclined to the field of chronic disease prevention and health services, which was in line with social development and the needs of the times.

Ethics review characteristics of clinical research of acupuncture and moxibustion

The elements of ethical review related to clinical research of acupuncture and moxibustion is discussed to provide ideas for various institutions to carry out relevant ethical review. It is believed that the ethical review of clinical research of acupuncture and moxibustion needs to focus on the specificity of acupuncture and moxibustion. Starting from the basic theory of traditional Chinese medicine, the theory of meridians and acupoints and the theory of syndrome differentiation along meridians, the key contents of ethical review such as intervention methods, grouping design and placebo control should be considered, so as to standardize the clinical research of acupuncture and moxibustion and protect the health and rights and interests of participants.

The literature sources and identification of ancient acupuncture prescription for headache

Ancient acupuncture and moxibustion prescriptions are one of the sources for evidence-based acupuncture research, representing the techniques features in treatment. This paper examines and analyses the literature of ancient acupuncture and moxibustion prescriptions for headache. It was found that repeated adaption and private changes of ancient acupuncture prescriptions was common. It was also found that the literature which reported the adaption of the indications of acupoints and the annotation of acupuncture and moxibustion in the form of poetry was often confused with the clinical acupuncture prescriptions. It is essential to trace the literature sources of ancient acupuncture prescriptions and to confirm the earliest documents extant for their authenticity and inheritance. In this sense, they are the two steps for review of the literature of ancient acupuncture prescriptions.

인공지능시대의 경혈 주치 연구를 위한 제언

Artificial intelligence technology sheds light on new ways of innovating acupuncture research. As acupoint selection is specific to target diseases, each acupoint is generally believed to have a specific indication. However, the specificity of acupoint selection may be not always same with the specificity of acupoint indication. In this review, we propose that the specificity of acupoint indication can be inferred from clinical data using reverse inference. Using forward inference, the prescribed acupoints for each disease can be quantified for the specificity of acupoint selection. Using reverse inference, targeted diseases for each acupoint can be quantified for the specificity of acupoint indication. It is noteworthy that the selection of an acupoint for a particular disease does not imply the acupoint has specific indications for that disease. Electronic medical record includes various symptoms and chosen acupoint combinations. Data mining approach can be useful to reveal the complex relationships between diseases and acupoints from clinical data. Combining the clinical information and the bodily sensation map, the spatial patterns of acupoint indication can be further estimated. Interoperable medical data should be collected for medical knowledge discovery and clinical decision support system. In the era of artificial intelligence, machine learning can reveal the associations between diseases and prescribed acupoints from large scale clinical data warehouse.

Sample size estimation in acupuncture and moxibustion clinical trials

The appropriate sample size estimation is very important in the design of clinical trials. However, insufficient or inappropriate sample size estimation is still a prominent problem in the currently published acupuncture and moxibustion clinical trials. At present, the superiority test, non-inferiority test and equivalence test have been widely used in acupuncture and moxibustion clinical trials. This article focuses on the application, calculation methods and PASS11 software using of these three hypothesis test types. In view of the problems in the estimation of sample size in acupuncture and moxibustion clinical trials, the particularity of sample size estimation in acupuncture and moxibustion is summarized from the aspects of parameter setting, ratio of intervention group and control group, and multi-group comparison, in order to guide acupuncture clinical researchers to correctly estimate sample size when conducting clinical trials.

Abstracts from Society for Acupuncture ResearchPandemics, Pain, & Public Health:Roles and Relevance of Traditional East Asian MedicineJune 14–17, 2021

Abstracts from Society for Acupuncture ResearchPandemics, Pain, &amp; Public Health:Roles and Relevance of Traditional East Asian Medicine<i>June 14–17, 2021</i>

Society for Acupuncture Research Award‐WinningAbstracts in Pandemics, Pain, &amp; Public Health:Roles and Relevance of Traditional East Asian Medicine,sponsored by the University of Michigan Departmentof Anesthesiology and Program in Integrative MedicineJune 14‐17, 2021

Society for Acupuncture Research Award‐WinningAbstracts in Pandemics, Pain, &amp; Public Health:Roles and Relevance of Traditional East Asian Medicine,sponsored by the University of Michigan Departmentof Anesthesiology and Program in Integrative Medicine<i>June 14‐17, 2021</i>

Call for Special Issue Papers: The World Acupuncture Forum: Deadline for Manuscript Submission: January 15, 2022.

Medical AcupunctureVol. 33, No. 5 Calls for PapersFree AccessCall for Special Issue Papers: The World Acupuncture ForumDeadline for Manuscript Submission: January 15, 2022Guest Editors: Gerhard Litscher, Frank Bahr, and Im Quah-SmithGuest Editors: Gerhard LitscherGerhard Litscher, MSc, PhD, MDsc; Head of the Research Unit for Complementary and Integrative Laser Medicine, and the Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine, and Chairman of the TCM Research Center Graz, Medical University of Graz, Austria.Search for more papers by this author, Frank BahrFrank Bahr, MD; EATCM, Munich, Germany.Search for more papers by this author, and Im Quah-SmithIm Quah-Smith, MD, PhD; Adjunct Lecturer, School for Women's and Children's Health, UNSW Medicine, University of New South Wales, Randwick, NSW, Australia; Auricular Medicine, Centre for WellBeing, The Mater Hospital, Wollstonecraft, NSW Australia; Roseville Wellness Group, Roseville, NSW, Australia.Search for more papers by this authorPublished Online:18 Oct 2021https://doi.org/10.1089/acu.2021.29186.cfpAboutSectionsPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail Dear Acupuncture Community:It is our pleasure to announce a new Special Issue on the “World Acupuncture Forum (WAF) Davos 2022” guest-edited by the team of Prof. Litscher, Dr. Bahr, and Dr. Quah-Smith.The editors invite manuscript submissions related to high-level acupuncture research and/or acupuncture practice of significant interest to the readership of Medical Acupuncture. Manuscript topics should be related to either the general aspects or specific aspects outlined by the World Acupuncture Forum. The full list of topics is below. Manuscript types may be original research, review articles, perspectives, commentaries, or letters to the editor.Main Topics (general aspects):Acupuncture in EuropeAcupuncture in ChinaAcupuncture in AmericaAcupuncture in AustraliaAcupuncture Research on Different ContinentsSpecial Topics (specific aspects):Acupuncture and COVID-19Acupuncture and mental healthTreatment of pain with acupunctureLaser acupuncture and innovative laser medicineAcupuncture and allergiesHow to handle effectively psychological injuries and traumas of soul with acupunctureAuricular medicine and dynamic pulse reaction (RAC)Acupuncture and addictionsSubmitted papers should not be under consideration for publication elsewhere.Further information on the World Acupuncture Forum (WAF) is available at https://www.eatcm.de/world-acupuncture-forum-davos-2022/The deadline for manuscript submission is January 15, 2022.Please review the Journal's Instructions for Authors, including Manuscript Types and Guidelines, at www.liebertpub.com/acuPlease submit your papers online to our web-based manuscript submission and peer-review system at https://mc.manuscriptcentral.com/acupunctureIf you are interested in having your manuscript published in this Special Issue, please do not hesitate to contact Managing Editor, Yael BenPorat (yaelbenporat@me.com). We look forward to hearing from you soon.Medical Acupuncture, published by Mary Ann Liebert, Inc., is the Official Journal of the American Academy of Medical Acupuncture. All members of the Academy receive a print subscription and online access to Medical Acupuncture as a benefit of their membership. The peer-reviewed Journal presents authoritative, evidence-based clinical papers, case reports, and research findings that integrate concepts from traditional and modern forms of acupuncture with Western medical training.Visit the Instructions for Authors:www.liebertpub.com/acuSubmit your paper for peer review online:https://mc.manuscriptcentral.com/acupunctureFiguresReferencesRelatedDetails Volume 33Issue 5Oct 2021 InformationCopyright 2021, Mary Ann Liebert, Inc., publishersTo cite this article:Guest Editors: Gerhard Litscher, Frank Bahr, and Im Quah-Smith.Call for Special Issue Papers: The World Acupuncture Forum.Medical Acupuncture.Oct 2021.315-316.http://doi.org/10.1089/acu.2021.29186.cfpPublished in Volume: 33 Issue 5: October 18, 2021PDF download

Obesity Animal Models for Acupuncture and Related Therapy Research Studies.

Obesity and related diseases are considered as pandemic representing a worldwide threat for health. Animal models are critical to validate the effects and understand the mechanisms related to classical or innovative preventive and therapeutic strategies. It is, therefore, important to identify the best animal models for translational research, using different evaluation criteria such as the face, construct, and predictive validity. Because the pharmacological treatments and surgical interventions currently used for treating obesity often present many undesirable side effects, relatively high relapse probabilities, acupuncture, electroacupuncture (EA), and related therapies have gained more popularity and attention. Many kinds of experimental animal models have been used for obesity research studies, but in the context of acupuncture, most of the studies were performed in rodent obesity models. Though, are these obesity rodent models really the best for acupuncture or related therapies research studies? In this study, we review different obesity animal models that have been used over the past 10 years for acupuncture and EA research studies. We present their respective advantages, disadvantages, and specific constraints. With the development of research on acupuncture and EA and the increasing interest regarding these approaches, proper animal models are critical for preclinical studies aiming at developing future clinical trials in the human. The aim of the present study is to provide researchers with information and guidance related to the preclinical models that are currently available to investigate the outcomes of acupuncture and related therapies.

Analysis of the Most-Cited Systematic Review or Meta-Analysis in Acupuncture Research.

Objectives The aim of the current study was to analyze the 100 most-cited systematic reviews or meta-analyses in the field of acupuncture research. Methods The Web of Science Core Collection was used to retrieve lists of 100 most-cited systematic reviews or meta-analyses in the field of acupuncture research. Two authors screened literature, extracted data, and analyzed the results. Results The citation number of the 100 most-cited systematic reviews or meta-analyses varied from 65 to 577; they were published between 1989 and 2018. Fourteen authors published more than 1 study as the corresponding author and 10 authors published more than 1 study as the first author. In terms of the corresponding authors, Edzard Ernst and Linde Klaus published the most systematic reviews/meta-analyses (n = 7). The USA published most of the systematic reviews or meta-analyses (n = 24), followed by England (n = 23) and China (n = 14). Most institutions with more than 1 study were from England (4/13). The institutions with the largest numbers of most-cited systematic reviews or meta-analyses were the Technical University of Munich in Germany, the University of Maryland School of Medicine in the USA (n = 8), the Universities of Exeter and Plymouth in England (n = 6), and the University of Exeter in England (n = 6). The journal with the largest number of most-cited systematic reviews or meta-analyses was the Cochrane Database of Systematic Reviews (n = 20), followed by Pain (n = 6). Conclusion Our study reveals that the 100 most-cited systematic reviews or meta-analyses in the acupuncture research field are mostly from high impact factor journals and developed countries. It will help researchers follow research hot spots, broaden their research scope, expand their academic horizons, and explore new research ideas, thereby improving the quality of acupuncture research.

Tracing origin and development of "Fenglong (ST 40) for phlegm": examination and verification

From the perspective of academic history, the background and evolution of "Fenglong (ST 40) for phlegm" were systematically summarized. As a result, it was found that in the early period, Fenglong (ST 40) was used for "tangible phlegm" of respiratory tract, but in the later generations, due to the comprehensive effects of various factors, the phlegm treated by Fenglong (ST 40) was generalized. In modern clinical practice of acupuncture and moxibustion, Fenglong (ST 40) is widely used for phlegm-related diseases. In addition, the knowledge content represented by "Fenglong (ST 40) for phlegm" showed evolution and change in academic heritage of previous dynasties. It is necessary for modern acupuncture researchers to systematically sort out, test and discriminate the habitual knowledge in combination with the background of traditional Chinese medicine, so as to promote the contemporary inheritance and application of traditional acupuncture theory and knowledge.

Study of the relationship between acupuncture dose and effect

Study of the relationship between acupuncture dose and effect

In the search of mobile target for acupuncture: why is mast cell?

Both clinical practice and basic research of acupuncture have pointed out that acupuncture treatment has specific tissue and cellular targets. In addition to the known fixed tissue targets such as nerves and blood vessels, the author analyzes the biological characteristics of other skin resident cells in the skin and concludes that cutaneous mast cells are the most suitable candidate for the cellular target of acupuncture. A hypothesis of the bionic acupuncture is proposed to explain the biological principles by which the innate immunity and healing system respond to acupuncture. The distribution of mast cells in the human skin is characterized by "approaching to the terminals and gathering at the orifices", and the cell density is highly correlated with the density of acupoints and the micro-acupuncture systems. These evidences all support that mast cells are the mobile target cells for acupuncture, which can explain some clinical phenomena and principles of acupuncture, and suggest mast cells as one of the tissue markers for acupoints.

Visualization analysis of traditional Chinese medicine for neurogenesis research based on CiteSpace

To analyze the research hotspots and trends of traditional Chinese medicine(TCM) for neurogenesis with use of CiteSpace 5.7.R3 software. The bibliometrics analysis on the literatures of TCM for neurogenesis from 1987 to 2020 included in the CNKI database was conducted to visualize the number of papers, authors, institutions and keywords. Totally 736 literatures were included and the volume of annual publications showed an upward in volatility. At present, several stable research teams have been formed, which were represented by DING Fei, ZHOU Chong-jian and ZHOU Yong-hong, but the cooperation was not close among the teams. According to the analysis of research institutions, Institute of Diagnostics of Hunan University of Chinese Medicine and Acupuncture Research Center of Tianjin University of Traditional Chinese Medicine produced largest number of literatures. The cooperation among institutions, with universities of TCM and affiliated hospitals as the main research force, was characterized by dominant cooperation among regional institutions and less cross-regional cooperation. Keywords analysis showed that in the field of TCM for neurogenesis, a lot of studies mainly focused on the disease field, treatment and medication, TCM therapy and molecular mechanism. The research on TCM therapy and molecular mechanism for neurogenesis of central nervous system will be the research hotspots in future.

Anesthetic Effect Research of Acupuncture Assisted General Anesthesia Combined with Epidural Anesthesia in Gynecological Laparoscopic Surgery

Anesthetic Effect Research of Acupuncture Assisted General Anesthesia Combined with Epidural Anesthesia in Gynecological Laparoscopic Surgery