The Andaman and Nicobar Islands have been actively seeking sustainable alternatives to plastic and recent research by the ICAR-Central Island Agricultural Research Institute (CIARI) and the ICAR-National Bureau of Plant Genetic Resources (NBPGR) has identified Macaranga nicobarica, commonly known as the “Giant leaf” plant, as a promising substitute for plastic packaging. This study investigates the potential of M. nicobarica as an alternative source for plastic plates, focusing on its growth, development, and leaf characteristics. Germplasm of M. nicobarica was collected from three locations in the Nicobar Islands and conserved for further study. Morphological observations were made on leaf production patterns and various leaf characteristics, and statistical analyses were conducted to compare these traits among different accessions of M. nicobarica and other relevant species (M. tanarius and M. indica). Significant variations were observed in leaf characteristics among M. nicobarica accessions, with some displaying larger dimensions and higher leaf area compared to others. Furthermore, M. nicobarica exhibited distinct differences in leaf characteristics compared to other species of the Macaranga genus. A dendrogram analysis confirmed the clustering of all M. nicobarica accessions, distinct from other studied species. The findings suggest that M. nicobarica, particularly accession IC: 626370, holds significant potential as an alternative source for plastic plates, owing to the size and texture of its large leaves. This research contributes to the ongoing efforts to reduce plastic dependency in the Andaman and Nicobar Islands, highlighting the importance of indigenous resources like M. nicobarica in fostering sustainable solutions for environmental challenges.