This work analyzes some considerations around biological determinism, linking them to social and racial inequality, intelligence, and comparative psychology research positions. This work is based on gender theory, which allows us to explain the fact that humankind is not just a product of nature, but one of historic processes and bio-social-cultural conditions. The epistemological posture ofthis theory is in the subject, where the historic dimension is not only an axia of analysis, but a part of epistemology. This leads to a subject structured through different institutions this breaking dual structures about reality and human behavior.