ResearchGate Research Articles

Oral Soft Tissue Metastasis from Breast Cancer as the Only Primary Source: Systematic Review.

Background Breast cancer is one of the most lethal neoplasms causing death. Oral cavity is the rare site of distant metastasis from breast cancer. Very little research has been conducted to date to analyze breast cancer as the sole primary source of metastasis to the oral soft tissues. The goal of this study was to examine the published cases of oral soft tissue metastasis from breast cancer as the only primary source to date. Methods An electronic search of the published literature was performed without publication year limitation in PubMed/Medline, Scopus, Google Scholar, Web of Science, Science Direct, Embase, and Research Gate databases, using mesh keywords like ("Breast cancer", OR "Breast carcinoma") AND ("Metastasis" OR "Metastases"), And ("Oral soft tissues" OR "Tongue" OR "Palate" OR "Tonsil" OR "Buccal mucosa" OR "Floor of mouth" OR "Vestibule" OR "Salivary glands"). We also searched all related journals manually. The reference list of all articles was also checked. Results Our research revealed 88 relevant papers (September 1967-September 2023) with 96 patients in total. The most predominant oral soft tissues involved were salivary glands followed by the gingiva, tonsils, tongue, and buccal mucosa. A total of 23% of patients died with an average survival time of 1 to 15 months. Conclusions Oral soft tissue metastasis from breast cancer is a rare event and has a bad prognosis. More cases need to be published to raise awareness of these lesions.

A Systematic Review on the Hemolytic Effect of Bisphenol-A on Human Erythrocytes (<em>In-vitro</em>)

Bisphenol A (BPA) is a high-production volume industrial chemical, and human exposure to BPA is essentially ubiquitous with the increased use of BPA-associated products. Though the ubiquitous nature of BPA exposure has resulted in circulating levels of BPA, as reported in numerous biomonitoring studies, a limited number of studies have been carried out to investigate the impact of BPA on human red blood cells. Yet the findings remain ambiguous. Thus, this study aimed to systematically review the published literature on the hemolytic activity of BPA on human erythrocytes. A systematic review of published literature was conducted following the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) approach. A comprehensive search of the literature was undertaken using Google Scholar, PubMed and Research Gate for studies published from 2015 to September 2023. The keywords "human erythrocytes", "Bisphenol-A", "in vitro", and "hemolysis" were included in the search. The search identified a total of 933 articles (PubMed = 3, research gate=99, and Google Scholar = 831). After following the exclusion and inclusion criteria, four full papers were entitled to review. In these four studies, they have incubated isolated human red blood cells with varying concentrations for different durations. BPA showed a dose-dependent and time-dependent hemolytic activity in-vitro on human erythrocytes. Reasons for BPA-induced hemolysis in erythrocytes involve the generation of reactive oxygen species. As there are contradictory observations, meta-analysis is recommended. However, no comprehensive investigations have been carried out to evaluate the impact of BPA on human red blood cells under physiological concentrations so far. Consequently, it is recommended that further research in this area be undertaken to provide a more robust understanding of the physiological implications of BPA exposure on red blood cell function.

Analysis of Neural Networks Used by Artificial Intelligence in the Energy Transition with Renewable Energies

Artificial neural networks (ANNs) have become key methods for achieving global climate goals. The aim of this review is to carry out a detailed analysis of the applications of ANNs to the energy transition all over the world. Thus, the applications of ANNs to renewable energies such as solar, wind, and tidal energy or for the prediction of greenhouse gas emissions were studied. This review was conducted through keyword searches and research of publishers and research platforms such as Science Direct, Research Gate, Google Scholar, IEEE Xplore, Taylor and Francis, and MDPI. The dates of the most recent research were 2018 for wind energy, 2022 for solar energy, 2021 for tidal energy, and 2021 for the prediction of greenhouse gas emissions. The results obtained were classified according to the type of structure and the architecture used, the inputs/outputs used, the region studied, the activation function used, and the algorithms used as the main methods for synthesizing the results. To carry out the present review, 96 investigations were used, and among them, the predominant structure was that of the multilayer perceptron, with Purelin and Sigmoid as the most used activation functions.

Interpersonal Psychological Theory of Suicide in Understanding Suicidal Behavior among Adolescents in Nepal

Suicidal behavior, a global public health issue, is one of the prevalent problems among adolescents in Nepal with highest rate of suicidal ideation and higher rates of suicidal attempt among the countries of South East Asia Region (SEAR). The Interpersonal psychological theory of suicide (IPTS) is a widely used and well-known theory that provides an interpersonal psychological framework which can contribute in understanding suicidal behavior. Although its application is found in international level, the lack of knowledge remains among Nepalese adolescents. Hence, this review is aimed to assess the applicability of IPTS in understanding suicidal behavior of adolescents in Nepal. A literature search was conducted using electronic databases (PubMed, Hinari, Nepjol, Research gate, and Google scholar). A scoping review of the articles published in peer-reviewed journals and grey literatures was done. We used the Preferred Reporting Items for Systematic Review and Meta-analysis Extension for Scoping Reviews (PRISMA-ScR) in reporting the review and six-step process recommended by Arksey and O’Malley (2005) was adopted. Boolean operators (AND, OR, NOT) were used in search strategy which helped in combining key terms. The studies which assessed the relation between the constructs of IPTS i.e., thwarted belongingness, perceived burdensomeness and suicidal behavior among adolescents in Nepal were included, i.e., 14 studies which met the inclusion criteria.The findings revealed various risk factors which support the use of IPTS as those relate with the constructs of thwarted belongingness and perceived burdensomeness to explain suicidal behaviors among adolescents. Therefore, the findings indicated the use of the framework provided by IPTS in understanding suicidal behavior among Nepalese adolescents as well as highlighted the importance of interpersonal risk factors to prevent suicidal behavior.

Drivers of changing cropping patterns in Nepal: A review

This paper reviews various aspects of drivers of changing cropping patterns in Nepal based on secondary data sources. Data were acquired from Google Scholar and Research Gate database 32 relevant professional journal articles in between 2000-2022 were intensively reviewed. The drivers of changing cropping patterns are complex and interrelated in the farming system. Spatial analysis of cropping patterns of different geographical scales shows that cropping pattern is an integral part of a behavioral focus to reflect the space relation of the community people. The drivers of changing cropping patterns are numerous and intricately linked. It is challenging to gauge the relative significance of the effects ascribed to each scale of the driver or the interactions between them at any particular geographic region. The study revealed that there are several types of drivers for changing cropping patterns. Among these various types of drivers, the theme of technological advancement/inputs, climate change, infrastructural development, road connectivity, and market demand play prominent roles in changing cropping patterns however other drivers such as off-farm employment, agriculture service extension/training, government policies, population growth/change/migration (rural to urban; international.), are also remarkable in this studies. In the Nepalese context, this study indicates that the more prominent role playing drivers of changing cropping patterns are technological advancement /inputs, infrastructural development and road connectivity, and market demand and climate change however land degradation and government policies also play a role to shifting cropping patterns. These all drivers interact and link with each other, leading to changing cropping patterns in Nepal.

The status of research on malnutrition among children under 5 years in Southern Africa: a systematic review

Malnutrition rates remain alarming with stunting declining too slowly while wasting still impacts the lives of many young children. Globally, 5.6 million children die before their fifth birthday annually, with 80% of these deaths occurring in Sub-Saharan Africa and Asia. A total of 29 most relevant articles were included, which followed the preferred reporting items for systematic reviews and meta-analyses for protocols (PRISMA-P). The literature search was conducted in multiple electronic databases, including Google Scholar, PubMed, and Research Gate. A large proportion of the literature focused on determining factors associated with malnutrition. Similarities were found amongst various articles with findings highlighting household food insecurity as a major threat that leads to inadequate feeding practices and consequently resulting in undernutrition. This review assessed the state of knowledge on malnutrition in Southern Africa. The authors identified knowledge gaps that should be considered for future research. We did not come across any evaluation studies assessing food security interventions in response to malnutrition. Moreover, sanitation in relation to malnutrition is not broadly researched. We recommend future studies to apply a cross-sectional analytic design with mixed methods, combining survey data, geographical data, household and key informant interviews. There is a need to map the prevalence of malnutrition in children under five years and providing more knowledge on vulnerability and contexts that influence malnutrition including socio-economic, environmental and infrastructural conditions. We further recommend the use of GIS databases to generate information on spatio-temporal patterns of malnutrition.

Fixative Solution for Macromolecules in Histological Preparations

The fixation process is subjected to preserve cells, tissues, and their components so that the structure can be maintained as their alive condition and prevent autolysis. This literature review purpose to determine the appropriate use of fixative solutions for several macromolecules, such as proteins, lipids, carbohydrates, and nucleic acids. The literature review data is obtained form the secondary data included books, journals, or articles which discussed about fixative solutions without a limitation on the year of publication. The databases were sourced from Google Scholar, PubMed, NCBI, Science Direct, SpringerLink, Research Gate, and Nature. The keywords for the book search were tissue processing, pathology, and histology. Keywords for searching journals or articles were protein fixation, formaldehyde fixation lipids, fixatives for nucleic acids, Glyo-Fixx fixatives, mercury chloride fixative lipids, formalin-fixed carbohydrates, and ethanol or methanol for fixative lipids. Based on the literature review conducted, it can be concluded that the use of fixative solutions is according to the macromolecules to be observed.

Implementation of Home-based Cardiac Rehabilitation Program in Patients with Coronary Artery Disease: A Literature Review

Introduction: Coronary artery disease (CAD) is the major cause of disability and death worldwide. The cardiac rehabilitation (CR) program is the management strategy for CAD patients with exercise as the main component to increase functional capacity. This program has been proven beneficial in reducing mortality and morbidity due to CAD. It also reduced the healthcare burden and improved the quality of life. Although the benefits of CR are widely proven, participation and adherence of CAD patients to this program are low. The home-based cardiac rehabilitation (HBCR) program is the strategy developed to increase the coverage of CR services. This program is equally effective as center-based cardiac rehabilitation (CBCR) and is considered safe. This review aimed to find out more about the HBCR program with a focus on its implementation in CAD patients.
 Methods: Original articles and systematic or narrative reviews were searched using PubMed, Google Scholar, and Research Gate databases. Further exploration of literature citations was also done to meet the inclusion criteria needed to explain the topic.
 Results: Compared to CBCR, the HBCR program provide comparable benefits, both in medical and functional outcomes. The HBCR program is proven to be feasible and safe with better adherence. The components of the HBCR program are generally the same as the CBCR program and direct supervision given in the CBCR program can be replaced by remote supervision through communication devices or home visits.
 Conclusion: The HBCR program can be used as an alternative to CBCR in managing patients with CAD.

Systematic Literature Review Etnomatematika: Pendidikan Matematika pada Kearifan Lokal Sasak

The aim of this research is to find out mathematical concepts related to the ethnomathematics of local wisdom of Sasak culture. This research is a Systematic Literature Review (SLR) which was carried out by identifying, reviewing, evaluating and interpreting all available research. The design used in this research is to summarize, review and analyze 9 articles with the scope of discussing the Ethnomathematics of Sasak Culture with details of one article published in the reputable journal Q2 and the rest in the accredited National Journal Sinta. Searches for these articles were carried out through online journals such as journal articles from Google Scholar, Research Gate, SINTA, DOAJ, and Scopus. The conclusion of this research is the finding of mathematical concepts related to Ethnomathematics, local wisdom of Sasak Culture, consisting of Flat Plane Geometry, Geometric Space Structures, Geometric Transformation Concepts, Measurement, Volume of Rotating Objects, Perimeter and Area of Flat Plane Structures.

Binge-Watching as Behavioral Addiction: A Systematic Review

In the recent past, binge-watching has emerged as one of the most prevalent pursuits among adults. Being a relatively new phenomenon, there is a pressing need to examine the literature on the associations of binge watching with various psychological correlates such as cognitive processes, emotional regulation, moods and sleep patterns. Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) model was employed for this systematic review. Relevant articles were collected using various databases including Google Scholar, Research Gate and PubMed. This resulted in a collection of 209 articles which were further screened based on the predefined inclusion and exclusion criteria. Out of these articles, 18 met the criteria and were included in the study. The findings revealed noteworthy associations between binge-watching behavior; particularly problematic patterns, and disruptions in mood and emotional dysregulation. The systematic review highlighted that the phenomenon of binge-watching as an addictive and problematic behavior has negative outcomes for individuals such as compromised executive functioning as well as cognitive deficits.

Pathophysiology and Clinical Manifestations of Hypogonadism

Hypogonadism is a condition where the function of the gonad glands decreases, resulting in a decrease in hormone levels due to the hypothalamus-pituitary-gonad (HPG) axis. Hypogonadism occurs in approximately 2.1% – 12.8% of the middle-aged to older male population. This article was written to find out more about explaining the pathophysiology and clinical symptoms of hypogonadism. The method used is literature reflection combined with related search sources from the National Center for Biotechnology Information (NCBI), Google Scholar, and Research Gate. The results of a literature review of articles carried out can conclude that hypogonadism often causes symptoms of delayed puberty, loss of libido, erectile dysfunction, loss of muscle mass, and depression. Hypogonadism is also classified based on the reason into primary and secondary hypogonadism. Primary hypogonadism occurs due to gonadal dysfunction, while secondary hypogonadism occurs due to dysfunction of the hypothalamus and/or pituitary gland.

Investment in National Pension Scheme: Issues and Trends

Purpose: Retirement is a time to leave from the job or work forever. Investing for retirement plays an important role. This study makes an effort to evaluate the various issues and trends of the investment in the National Pension Scheme (NPS) by an individual. Since the primary goal of this study was to assess the issues and trends of the investment in the National Pension Scheme for retirement benefits, and the study also evaluates its advantages, benefits, constraints, and disadvantages through ABCD analysis. Design: This research is conducted through secondary sources in order to provide a full-fledged evidence-based study on the issues and trends in the investment on National Pension Scheme. The semi-systematic review is conducted using various published reports and articles from sources including Springer, Tailor & Francis, Emerald, Google Scholar, Srinivas Publication, Research Gate, SSRN, etc. Findings: The result of compressive review revealed that in India, people save as a part from their income but very few invest for their retirement. The reasons for not investing for retirement is classified under two major factors i.e., internal and external factors. NPS provides pension scheme as well as investment scheme which allows the member to choose their investment in different assets. Unfortunately, due to lack in financial literacy and financial knowledge on the investment of retirement products and plans. Practical Implications: This research provide a guide for members who wish to invest for their retirement and create an awareness of the numerous challenges by the citizens by the policy makers and improved performance for the benefit of the citizen. It serves as a source of information for NPS users to comprehend the advantages of enrolling in pension plans for their retirement. Originality/value: This study as per the secondary data may provide overall view on the National Pension Scheme and may help the customers for better understanding about the pension scheme and also assist the policy makers and pension regulator to promote investment on the retirement plans; but the concept of NPS can be better understood through primary survey, therefore it is the limitation of the study. Paper type: Case Study.

Determining Factors For The Accuracy Of Diagnosis Codes Using ICD-10 In Obstetric Cases: Riview Systematics

Medical record coder has complete duties, responsibilities, authority and rights to carry out medical record service activities in health service units. The accuracy of the disease diagnosis code is crucial, the accuracy of the diagnosis code will affect the claim for treatment costs, the allocation of health resources and the accuracy of hospital statistical data. This research systematically reviews articles uses the PRISMA diagram to help sort articles to use, also have criteria: research data is data from Indonesia, uses Indonesian or English, the article was published 2018-2023, the article can be downloaded in full and is not a thesis. This research searched articles through the Google Scholar database, Garuda Portal and Research Gate. As a result of the review of the 7 articles, it is known that inaccurate diagnosis codes in obstetric cases are caused by 7 different factors. The most influential factors are information in MRD (Medical Record Document) is written as unclear or incomplete. The second reason is MRD is not double-checked or inspected and the last is code errors in categories and sub-categories.

REHABILITATION AFTER AN ATHLETE'S ANKLE INJURY

Introduction: A bone fracture is a break in the continuity of bone tissue, caused by the action of an external or internal force on the bone. Ankle sprains are one of the most common injuries among athletes. Physically active people who participate in activities that require jumping, changing direction, and turning have an increased risk of ankle sprains. Ankle sprains and the repetitive trauma often associated with this condition can lead to long-term disability, lost time from activity, and financial burdens for athletes. Methods: The work is non-experimental (qualitative research), i.e. a review of scientific literature. The search included an overview of the relevant databases: Medline, PubMed, Google Scholar, Research Gate. The literature review includes 4 randomized clinical trials and 1 randomized single-blind trial. The mentioned databases were searched with the help of keywords: athletes, injury, ankle joint, rehabilitation. Results: Through a scientific review of the literature, the results of the significance and productivity of the application of rehabilitation in athletes with an ankle injury are presented. The results include the presentation and analysis of five published scientific papers in the period 2018-2020. The studies used for this review were published in India, Saudi Arabia, Iran, United States, Austria. Conclusion: By reviewing the scientific literature, it can be concluded that there are improvements in the quality of life of athletes after an ankle injury. The greatest improvements were noted in strength, balance and functional task performance. The application of the rehabilitation program plays an important role in reducing pain and stabilizing the knee joint.

The Effects of Passion Fruit (Passiflora Edulis) Seed Extract For Health Benefit

This study discusses the health benefits of the content of passion fruit (Passiflora edulis) seed extract. Google Scholar, Research Gate, and Mendeley were used as the search engine. The keywords were Passiflora edulis, passion fruit seed, antioxidant, and piceatannol. The benefits of passion fruit seed extract were analyzed from 21 articles. Twenty-one articles are used to demonstrate the health benefits of passion fruit (Passiflora edulis) seeds. The study's conclusions indicate that passion fruits may have anti-photoaging, anti-inflammatory, heart, liver, and kidney protective properties. They may also help treat skin conditions like striae distensae and acne vulgaris, as well as have anti-obesity, anti-hypertensive, anti-diabetic, anti-tumor, and anti-cancer properties. It is suggested where future research should go to improve the use of products made with passion fruits. It is hoped that more studies on the health benefits of passion fruit will be carried out using age-specific criteria, a larger sample size, and gender parity. Further prospective research is needed

Diet-Related Anemias: A Comprehensive Review on Types, Causes, Diagnosis, and Treatment

Background: Anemia, a prevalent blood disorder characterized by reduced red blood cells or hemoglobin, has diverse etiologies related to nutritional deficiencies, notably iron, vitamin B12, and B9. Its impact on quality of life is especially significant in elderly individuals and those with chronic conditions. Objective: This systematic review aims to collate and synthesize the current literature on nutrient-related anemias, focusing on types, pathophysiology, diagnosis, and treatment. Methods: A thorough search was conducted in databases including Google Scholar, PubMed, and Research Gate using keywords such as "anemia," "types," "pathophysiology," "diagnosis," and "treatment." The review encompasses studies that detail the prevalence, causes, symptoms, risk factors, diagnostic methods, and treatment options for anemias related to iron, vitamin B12, and B9 deficiencies. Results: The review found that anemia affects approximately 24.8% of the global population, with higher prevalence rates in vulnerable groups such as infants, children, and pregnant women. Iron deficiency anemia, the primary form globally, is prevalent in various populations due to factors like poverty, malnutrition, and gastrointestinal conditions. Diagnostic approaches include both traditional laboratory tests and newer metabolite tests like homocysteine and methylmalonic acid. Treatment strategies vary based on the type of deficiency and include oral and intramuscular supplements, with intravenous iron for malabsorption cases and folic acid for folate deficiency. Conclusion: Early detection and effective treatment of diet-related anemias are crucial to prevent serious complications and mitigate their impact on quality of life. The review highlights the importance of tailored treatment approaches, including dietary changes, supplements, and medications, to address the specific needs of individuals with different types of anemia.

An Ecocritical Reading of Arundhati Roy’s Select Works – A Literature Review

Purpose: The theme of ecocriticism as it is presented in Arundhati Roy's nonfiction writings is the focus of the study. The interdisciplinary study of the environment and literature is known as ecocriticism. Several of Arundhati Roy's chosen writings contain allusions to ecocriticism. The challenges people had to deal with because of the different environmental crisis that mankind had caused are explored in ecocritical literature, especially nonfiction works. The purpose of the study is to investigate how ecocriticism is used in the nonfiction works of the author selected for this study. A careful reading of Roy's works demonstrates the impact of the suffering the individuals endured. Design: In order to identify the research gap, a review of the literature is conducted by gathering data from secondary sources like peer-reviewed journals, national and international publications, the internet, and research sources like Google Scholar, Research Gate, SSRN, Elsevier, and Academia. Using ABCD analysis, the main points of the study are highlighted. To complete the proposed research, information is gathered from academic publications, doctoral theses, scholarly articles, and websites. The methodology utilized largely relies on gathering, analyzing, and interpreting prior knowledge. The methodology will use the textual analysis and comparison method. A close reading of a few of Arundhati Roy’s works will be done on the related topics. The APA Manual has been used to conduct the study's analysis in accordance with its guidelines. Findings: After reviewing numerous papers, books, and theses, it has been determined that the focus of the study will be on ecocriticism in a few key pieces of Arundhati Roy. It demonstrates that ecocriticism studies the goals intended to take a review of the literature and a thorough investigation of the problem at hand. Through a parallel reading of the fiction works with her non-fiction works, the research hopes to gain a deeper understanding of Arundhati Roy's works. Ecocriticism in nonfictional works is not emphasized in analyses of these important literary works. Paper Type: Literature Review

Systematic Review: The Effect of Fe Supplementation on Increasing Haemoglobin Levels in Female Adolescent

Anemia is related to nutritional problems, where hemoglobin levels in the blood are lower than normal. One age group that is risk to anemia is female adolescent because this age is a growth period that requires higher levels of nutrients, including iron. Prevention and treatment of anemia which is by providing iron supplementation. Giving iron supplementation on female adolescent with the right and effective dose can increase iron level in the body if it consumed regularly. To find out more about the effect of iron supplementation on hemoglobin levels in female adolescent. This study used systematic review and the sources were obtained from the database PubMed, Google Scholar, Cochrane Library, and Research Gate. This systematic review shows a relationship between Fe supplementation and hemoglobin levels. Referring to the results of various studies that have been carried out, it shows that there is a significant effect of Fe supplementation on increasing hemoglobin levels in young women.

The Use of Podcast to Teach Listening Comprehension to EFL Students: A Library Research

This research provides a review of the current literature on podcast in listening comprehension of EFL students. The type of research is library research study. The aim of this research is to analyze the effect of podcast in improving listening comprehension skills on EFL students. This paper reviewed six articles conducted between 2010-2020 utilizing multiple databases, they are ProQuest, EBSCOhost, and Springer Link through the digital library e- resource Perpustakaan Nasional RI. Furthermore, Google Scholar and Research Gate were used as additional resources. Each relevant publication screened according to some parameters; year of publishing, country, research purpose, research participant, methodology, research finding, type of article, and article in English text. A preliminary synthesis indicates that the majority of studies related to podcasts in improving listening comprehension to EFL students focused on the themes namely: (1) the effect of listening to podcast in improving students’ listening comprehension and (2) how podcast improve students’ positive perception and satisfiction in learning, then finally affected the improvement of students’ listening comprehension skills. A number of suggestions for future research have emerged from the quality and the content of previous studies. They are methodology and quality design of podcast to determine the long-term effects of podcasting on learning outcomes.

Mental optometry: Perceive to see with the mind’s eye

Mental optometry is a newly recognized word that refers to the interaction of the mind, brain, and sensory perceptions. The pattern established by behavioural optometry's research and assumption linking bodily orientation to the physical field of vision will be followed by the mind's eye, emotions, and actions. All three theories imply the presence of such an idea as a fundamental component of their systems, even if it isn't formally stated. The database was compiled using PubMed, PubMed Central (PMC), the Cochrane library, Google scholar, and research gate. Mental Optometry provides a neurobiologically informed knowledge of mood, emotion, and thinking. Visual stimulus interpretations, enabling for therapeutic treatments to help patients recognize and rectify skewed judgments. Optometrists have an important role in patients with mental illness. Finally, we must evaluate how enhancing ocular health and visual suppleness may assist our patients improve their overall feeling of well-being.