Research Ethics Committee Research Articles

Comparative Study between Bupivacaine versus Bupivacaine with Dexmedetomidine in Ultrasound Guided Transversus Abdominis Plane Block as Postoperative Analgesia in Open Inguinal Hernia

Abstract Background A recent myofascial plane block, the transversus abdominal plane block (TAP), has been shown to lessen not only postoperative discomfort after surgery of inguinal hernia but also hospital stay. It is our objective to achieve postoperative satisfaction regarding the pain with the least side effects as related with opioids. Methods The study was registered at Pan African-Clinical Trial Registry.org with ID of (PACTR 202301487176282), randomized clinical trial, after obtaining approval from the Research Ethical Committee of Ain Shams University, this study was done in the general surgery theatres of Ain Shams University Hospitals for 12 months. Results In this study, TAP block with dexmedetomidine was more effective than TAP alone as measured by visual analog scale (VAS) scores, regarding first analgesic request and change in vital data. Significant differences in VAS scores were observed at 6 hours up to 24 hours postoperatively (p < 0.01), but not during the first 6 hours. Heart rate was obviously diminished in the Bupivacaine with Dexmedetomidine (BD) group compared to the Bupivacaine (B) group starting at 2 hours postoperatively, while mean blood pressure was eased from 6 hours up to 24 hours postoperatively. Total analgesic consumption and time to first analgesic request were decreased in the BD group, while the incidence of nausea and vomiting were similar between the two groups. Conclusions The addition of dexmedetomidine to bupivacaine in TAP block extends the duration of time at which first dose of rescue analgesia and also reduced the total dose of opioid requirement in the first 24-h postoperatively.

Rapid Access Diagnostics for Asthma (RADicA): protocol for a prospective cohort study to determine the optimum series of investigations to diagnose asthma using conventional and novel tests

IntroductionThe diagnosis of asthma is often based on characteristic patterns of symptoms in the absence of an alternative explanation, resulting in over and under diagnosis. Therefore, diagnostic guidelines usually recommend...

Semaglutide treatment for PRevention Of Toxicity in high-dosE Chemotherapy with autologous haematopoietic stem-cell Transplantation (PROTECT): study protocol for a randomised, double-blind, placebo-controlled, investigator-initiated study

IntroductionCancer treatment with high-dose chemotherapy damages the mucosal barrier of the gastrointestinal (GI) tract and is associated with severe toxicity involving mucositis, severe inflammation and organ dysfunction. Currently, there is...

Predicting mucosal inflammation in IBD patients using patient-reported symptom scores and a faecal calprotectin home test: protocol for a multicentre prospective validation study

IntroductionCrohn’s disease and ulcerative colitis are chronic inflammatory bowel diseases (IBD) with a relapsing-remitting nature. With adequate non-invasive prediction of mucosal inflammation, endoscopies can be prevented and treatment optimised earlier...

Comparing qualitative and quantitative echocardiographic markers to assess cardiac contractility in newborn infants: protocol for a prospective cohort study

IntroductionNeonatologist-performed echocardiography (NPE) is increasingly used in the neonatal intensive care unit, aiding clinicians in enhancing diagnostic precision and guiding treatment decisions based on underlying pathophysiology. Experienced NPE operators typically...

Study of the Effect of HCO3 Supplementation on Serum α-Klotho Protein Level in Diabetic Kidney Disease. Pilot Study

Abstract Background Chronic kidney disease (CKD) was prevalent worldwide in the middle-aged and old-aged population. It has been recognized as an important disease threatening human health. Individuals with CKD are at risk of bone disorders, vascular abnormalities, and premature mortality due to changes in Ca2 and PO4 haemostasis. Aim of the Work To study the effect of oral sodium bicarbonate supplementation on soluble α-Klotho serum levels in diabetic patients with chronic kidney disease (stage 3b:4) according to the CKD-EPI formula. Patients and Methods This study was conducted on 44 diabetic patients with CKD stages 3b-4 according to the CKD-EPI formula ESRD recruited from Inward and OPC patients at El-Demerdash Internal Medicine Hospital. Their age ranged from 26 to 76 year. This study was conducted from June 2023 to November 2023; each participant signed informed consent. The study was approved by the Research Ethical Committee of Faculty of Medicine, Ain Shams University in April 2023. Results The mean age in cases was 57.1 ± 12.9 years was comparable to the control 55.1 ± 11.3 years with no significant difference between groups (p > 0.05). As regard sex distribution of the 44 patients included, males were 45.5% and females 54.5% with no significant difference between groups (p > 0.05). In our study there was no statistically significant difference between the two groups regarding DM duration (p > 0.05) or treatment also regarding presence of HTN or antihypertensive (p > 0.05). Also results showed no significant difference between cases and control as regard serum creatinine, eGFR, calcium, phosphorus, PTH and HBA1c (p > 0.05). As regards p/c ratio, there was significant difference between cases and control (P < 0.05). An interesting finding in this work was the significant increase in serum alpha klotho after 6 months of HCO3 supplementation, The Klotho (pg/mL) Before ranged from 296.1 to 730.2 with mean 388.5 ± 100.6 and the Klotho (pg/mL) After ranged from 426.1 to 933.3 with mean 641.5 ± 131.1. Conclusion There was highly significant difference found between before and after sodium bicarbonate supplementation in terms of Klotho and Hco3 in chronic kidney disease patients stage 3b to 4.

Role of Ultrasound in the Evaluation of Skeletal Muscle Changes in Patients with Type 2 Diabetes Mellitus

Abstract Background Diabetes is a global public health problem, with type 2 diabetes mellitus (T2DM) accounting for more than 90% of the diabetic population and it has been consistently reported as one of the strongest correlates of mobility limitation, especially in older people, and a potential risk factor for future mobility disability and loss of independence. Long-term complications and diabetes-related comorbidities only partially explain the excess risk of disability associated with diabetes. Changes in body composition, in particular progressive loss of muscle mass and increase in fat mass, with decline in muscle strength and quality have been proposed as additional potential mediators of the association between diabetes and disability. Aim of the Work to investigate the differences in Skeletal muscle ultrasound features in people with and without type 2 diabetes mellitus. Patients and Methods This was a Case control study conducted at the Ultrasound Radiology Unit, Radiology Department, Ain Shams University Hospitals from July, 2023 to January 2024. The study was performed on simple random sample consists of 36 T2DM patients on regular follow up in the endocrinology clinics in Ain Shams University Hospitals. And 36 Healthy controls came for routine checkup in Ain Shams University Hospitals clinics and meeting the study inclusion criteria. A signed informed consent was obtained from all patients and controls prior to inclusion in the study after explaining the procedure details. The approval of research ethical committee of faculty of Medicine - Ain Shams University was obtained before starting the study. The privacy of participants and confidentiality of data was guaranteed during the various phases of the study. Results we measured three ultrasonic parameters. MT, FL and PA. The FL and PA are measured in both relaxed and contracted states. the DPN group had the lowest MT, FL at both rest and contracted states and PA at contracted state as well as the lowest ΔFL and ΔPA. The control group had the highest MT, FL at both rest and contracted states and PA at contracted state as well as the highest ΔFL and ΔPA. The non-DPN group had intermediate values for the same variables. The differences among the groups were statistically significant for all the variables except for the pennation angle at rest. It showed that the ΔFL of the DPN group was significantly lower than that of the non-DPN group (p < 0.001), which was similar to a previous conclusion that the gastrocnemius fascicles undergo the smallest length changes in a DPN group. Conclusion The combination of MT,ΔFL and ΔPA of the MG showed high-diagnostic accuracy (sensitivity >80%; specificity >95%) for predicting DPN, which could be used for rapid screening in the future. Early muscle ultrasound screening should be timely carried out in patients with T2DM, especially those with a long disease course and poor long-term blood glucose levels, and there is no difference between men and women.

NEARER SCAN (LENO BESIK) evaluation of a task-sharing echocardiographic active case finding programme for rheumatic heart disease in Australia and Timor-Leste: protocol for a hybrid type II effectiveness-implementation study

IntroductionRheumatic heart disease (RHD) is underdiagnosed globally resulting in missed treatment opportunities and adverse clinical outcomes. We describe the protocol for a study which aims to co-design, implement and conduct...

Comparative Study between Ultrasound Guided Quadratus Lumborum Block vs Intraperitoneal and Perioportal Bupivacaine Infiltration as Post Operative Analgesia after Laparoscopic Cholecystectomy

Abstract Background Poorly controlled acute pain after abdominal surgery is associated with a variety of unwanted post-operative consequences, including patient suffering, distress, respiratory complications, delirium, myocardial ischemia, prolonged hospital stay and an increased likelihood of chronic pain. Objective To test the efficacy of QL block versus intraperitoneal and periportal infiltration with local anesthetic agent in providing postoperative analgesia after laparoscopic cholecystectomy. Patients and Methods Double-blinded randomized controlled clinical study [both the patient and the operator (the surgeon in intraperitoneal and periportal bupivacaine and the anesthetist in QL block) were blinded], After Approval was obtained from the research ethics committee of anesthesia and intensive care department, Ain Shams University. Results The results of the study revealed that the Patients receiving QLB had significantly longer time to first rescue analgesic and significantly lower total opioid consumption in first 24 h post operative compared with patients who received Intraperitoneal and periportal infiltration. Conclusion Bilateral QL block was effective in providing postoperative analgesia (significantly longer time to first rescue analgesia) and reduced postoperative opioid consumption in the first 24-h after laparoscopic cholecystectomy under general anesthesia, compared to intraperitoneal and periportal infiltration. This technique can be a promising mode of postoperative analgesia where epidural catheter insertion is contraindicated.

Photobiomodulation therapy to prevent oral mucositis and functional impairment in adult patients with haematological cancer undergoing haematopoietic stem cell transplantation: randomised trial protocol

IntroductionOral mucositis is a highly prevalent condition in individuals treated for haematological neoplasms, primarily during haematopoietic stem cell transplantation (HSCT). The condition is known to delay recovery processes, increasing the...

The CEP-Conep System in 2020: confronting COVID-19, challenges and lessons learned.

This paper presents the structuring dimensions of the CEP-Conep System in order to understand the actions promoted by the National Research Ethics Commission in response to demands for the processing and ethical analysis of research protocols related to COVID-19 in 2020. Based on CEP-Conep System public documents, an assessment of legislation, from 1988 to 2020, and its extension in terms of the number of Committees, users, and protocols, from 2012 to 2020 was presented. The minutes of Conep's Ordinary Meetings (RO), for 2020, of a confidential nature, were analyzed, to verify adaptations to the pandemic. At the end of 2020, the System had 844 Committees, 854,741 users, and 701,791 analyzed protocols. The Commission centralized the analysis of COVID-19 protocols, in January 2020, and promoted three decentralizations, as more knowledge was generated, with vaccine protocols for COVID-19 remaining centralized. The history of the CEP-Conep System provided ballast for the adoption of management, educational and communication measures that accelerated the approval of protocols and made the process transparent. The absence of indicators made it impossible to evaluate the performance in 2020, which was apparently satisfactory.

Clinical, radiographic and biochemical assessment of proximal cavities restored with composite resin using incremental vs. bulk packing techniques: One-year randomized clinical trial

BackgroundBulk-fill resin composites may suffer from recurrent caries around compound proximal restorations in posterior teeth, especially at the proximo-gingival interface.Over 12 months, will the bulk fill technique affect the caries recurrence rate at gingival margins when compared to the conventional incremental packing technique? How early will the first clinical, radiographical, and biochemical evidence of caries recurrence occur?MethodsAfter randomization, in 30 patients with two compound (OM or OD) supragingival lesions, one tooth was restored using the bulk fill technique on one side (group 1) (n = 15). In contrast, the other tooth on the other side was restored utilizing the incremental layering technique (group 2) (n = 15). Both teeth received restorative material (X-tra fil, Voco, Cuxhaven, Germany). The FDI criteria were used to evaluate restorations. As for the periodontal assessment, the gingival index, plaque index, papillary bleeding scoring index and periodontal pocket depth were evaluated. The gingival crevicular fluid (GCF) specimens were gathered, and MMP-9 was extracted and quantitated by ELISA. A customized radiographic template was designed, and 3D printed digital bitewing radiographs were taken. Assessments were done clinically, radiographically and biochemically at baseline (1 week) and after 3, 6 and 12 months. Data was statistically analyzed.ResultsThe null hypothesis was accepted clinically; no statistically significant differences appeared between bulk and incrementally filled posterior restorations. As for the radiographic assessment, the null hypothesis was accepted except for increased periodontal ligament width at 3 months. The null hypothesis for the biochemical evaluation was rejected as there were significant changes in levels of MMP-9 at different testing times.Conclusions1. With similar results but less sensitivity and significant time saving, the bulk fill technique can be considered an efficient alternative to the incremental fill technique in restoring proximal cavities. 2. Early evidence of caries recurrence can be correlated to an increase in the MMP-9 level in gingival crevicular fluid, followed by an increase in radiographic periodontal ligament width measurement.Trial registrationAn ethical approval from the Research Ethics Committee at the Faculty of Dentistry, October 6 University, (Approval No. RECO6U/5-2022). The study was registered at the Pan African Clinical Trials Registry on 24/07/2023 with an identification number (PACTR202307573531455).

Views of research ethics committee members on end-of-participation communications for trial participants who stop taking part: a cross-sectional survey study

BackgroundGiving information to trial participants who stop taking part could support them through what can be a difficult process. We previously developed guidance around the ethical acceptability of such information provision, and about how trialists can develop suitable communication materials. There is limited evidence about what research ethics committees think of this issue, and limited guidance about what level of oversight they should have over the proposed communications, or post-consent participant communications generally. We conducted a survey of UK ethics committee members to address these points.MethodsThe survey was co-developed by public contributors and trialists who had previously worked together on the communications guidance. We asked respondents if they agreed with the general idea of informing participants who stop taking part, if they had ever been requested to review similar communications, and what level of ethics committee review they might recommend. The survey was primarily conducted online. It was reviewed by three ethics committee members before finalisation and shared directly with all UK ethics committee members. We analysed quantitative questions descriptively and used inductive analysis for open questions to identify common themes.ResultsNinety-one ethics committee members participated (nearly 10% of all UK members). The sample was similar to reported data about all members in terms of several personal characteristics. Most respondents (83%) agreed with our project’s rationale. Only 23% of respondents reported having been asked to review an end-of-participation information sheet before. Respondents gave various answers about the level of ethics committee review required, but most supported a relatively proportionate review process. Common concerns were about the risk of coercion or making participants feel pressured.ConclusionsOur survey suggests that ethics committee members generally support providing information to trial participants who stop taking part, if risks to participants are mitigated. We believe our guidance already addresses the main concerns raised. Our respondents’ lack of prior experience with end-of-participation information sheets suggests that participants are not getting information they want or need when they stop participating. Our results help clarify how ethics committee should oversee post-consent participant communications, but further guidance from research regulators could be helpful.

A Local Flavor: Karaman Stuffed İlisıra

Turkish culinary culture has a very rich variety of food and reflects the cultural heritage of the society. Although there are regional differences, meals are included in many rituals from the wedding meal to the circumcision dinner. Traditionally prepared local dishes are preferred because of the organic products used. Local dishes are effective on gastronomic tourism, which is one of the alternative tourism types. It is known that some traditionally prepared local dishes are being forgotten due to currents such as fast food. In this study, which is a culinary culture research, it is aimed to determine the preparation, presentation, consumption style, and distinctive features of stuffed ilisıra, which is among the traditional dishes of Karaman, to be recorded in order not to be forgotten and to bring it to the literature. In accordance with this purpose, in the study, qualitative research method was preferred, and face-to-face interview technique was used as data collection tool. With the consent of the interviewed participants, the interviews were recorded on a voice recorder. Participants were chosen among those who know how to make Karaman Stuffed Ilisira and have a taste for it. The data obtained were divided into themes using the descriptive analysis method and supported by the direct statements of the participants. The participants stated that the eggplant they grow in their own gardens, Karaman type bulgur and minced meat made from the meat of animals grazed in the region are used in the meal. At the end of the research, it was determined that the inner mortar was prepared by adding onion, pepper, tomato, parsley, tomato paste, red pepper, salt, egg, and minced meat and kneading thoroughly. It has been concluded that the eggplants are a local flavor prepared by cutting the eggplants in half horizontally and then vertically and placing the stuffing between the eggplants. The study was conducted with the approval of the Karamanoğlu Mehmetbey University Social and Humanities, Scientific Research and Publication Ethics Committee, dated 27.01.2023, meeting number 02, and decision number 02-2023/21. It is recommended to take part in the business menus of local dishes, to increase the recognition and to contribute to gastronomy tourism.

ANALISIS FAKTOR-FAKTOR YANG MENGHAMBAT KAJI ETIK PROTOKOL PENELITIAN: STUDI PADA KOMITE ETIK PENELITIAN FAKULTAS KEDOKTERAN UNIVERSITAS SEBELAS MARET, SURAKARTA

Ethics review is essential prior to conducting research involving humans and animals. This study aimed to evaluate the effectiveness of ethics review procedures and identify the causes of delayed ethical approval of the protocols submitted to Research Ethics Committee of the Faculty of Medicine, Universitas Sebelas Maret during 2022-2023. Retrospective data collected include protocol identity number, institution and educational level of the proposer, research type, date of protocol submission, completion of initial ethics review, and issuance of the ethical clearance certificate. A total of 458 protocols were received over 2 years period but the processing of 8 protocols were discontinued so that those 8 protocols were excluded from further analysis. Of the 450 protocols analysed, most involved human subjects (331; 73.6%). The majority of proposers were from UNS (309; 68.7%), were students (353; 78.4%), and had undergraduate education (166; 36.9%). The duration of the initial ethics review was generally <2 weeks (90.4%). Most (92.7%) protocols needed revision. The majority (66.4%) of proposers needed <2 weeks to revise the protocol. The total time for the entire ethics review process was 22.9 ± 14 days. Further evaluation found that the average duration needed for protocol revision was longer than that for reviewing (16 vs 9 days). It can be concluded that the ethics review process ran effectively so that almost all protocols submitted could undergo initial reviews in a relatively short time. The delayed ethical approval was due to the slow protocol revision process by the proposers.

Evaluation of the Causative Microorganisms and Antibiogram Results in Women with Vaginal Swab Culture Taken with Prediagnosis of Vaginitis

Aim: Vaginitis occurs when the vaginal flora is disturbed. This study aimed to evaluate the demographic data, causative microorganisms, and antibiogram results of women who underwent vaginal swab culture with a prediagnosis of vaginitis. Methods: Vaginal swab samples from 314 women who visited the Kafkas University Department of Obstetrics and Gynecology were included in the study. Women with immunosuppressive diseases, gynecological malignancies, and IUD use were excluded. Vaginal discharge or swab samples were Gram stained and cultured on various media. Microorganisms were identified using conventional and biochemical methods, and antibiotic susceptibility tests were performed using the Kirby-Bauer disk diffusion method, according to the EUCAST guidelines. Statistical analyses were performed using SPSS, with categorical variables assessed using the chi-square test or Fisher's exact test, and continuous variables assessed using the Mann-Whitney U test. The study complied with the recommendations of the Declaration of Helsinki for human biomedical research and was approved by the Non-Interventional Clinical Research Ethics Committee of the Kafkas University Faculty of Medicine. Results: The median age of 314 women included in this study was 39 (20-69) years. . In total, 73.6% (n=231) were premenopausal, 24.5% (n=77) were postmenopausal, and 1.9% (n=6) were pregnant. The most common complaint was abdominal/pelvic pain (142, 45.2%). Vaginal cultures from 123 women (39.1%) showed the growth of different microorganisms. The most common causative microorganism was Escherichia coli (41.5%). According to the antibiogram results, the most sensitive antibiotic was gentamicin (65.9%), and ampicillin (52.8 %) was the most resistant. Conclusion: It is important to quickly and accurately identify microorganisms involved in the etiology of the correct treatment.

Exploring Allied Health Professionals’ Perceptions and Practice Regarding Recommendations for Intensity of Multidisciplinary Therapy for Stroke Patients: A Qualitative Study

Abstract Background Stroke is a leading cause of death and disability in Ireland; approximately 7,500 Irish people have a stroke every year. Rehabilitation is a key aspect of stroke care; greater amounts of therapy are associated with better recovery. Data from the Irish National Office of Clinical Audit shows that stroke survivors often do not receive recommended amounts of therapy. The recently updated UK and Ireland stroke clinical guidelines now recommend larger amounts of therapy time. This qualitative study explored how allied health professionals (AHPs) feel about the recommendation, and what methods they employ in working to achieve recommended amounts of therapy. Methods This study used a qualitative research design employing semi-structured interviews to collect data. Participants were AHPs working in stroke care in Dublin, Ireland, and were recruited using a combination of purposive and snowball sampling. Interviews were audio-recorded, transcribed, and analysed using the Braun and Clarke six-step thematic analysis method. An external validator was utilised for code and theme validation. This research was approved by the Royal College of Surgeons in Ireland Research Ethics committee. Results Two main themes emerged: ‘Barriers and enablers to achieving guideline recommended therapy time’ and ‘methods of increasing therapeutic time’. Patient factors and clinical resources impact on the provision of therapy post-stroke. Overall, participants felt positive about the recent guideline recommendation for increased therapeutic time. Various methods are employed to augment patient therapeutic time, including technology and semi-supervised practice. Therapy assistants play an important role in achieving greater amounts of therapy. Conclusion AHPs see the new recommendation as challenging but are generally keen to try and achieve it, citing benefits of increased therapy time for patient outcomes. AHPs utilise a wide range of methods to optimise therapeutic time for stroke patients. The role of therapy assistants in supporting delivery of larger amounts of therapy time warrants further evaluation.

Assessing the Sympatholytic Effects of SGLT2 Inhibitors in Anuric Haemodialysis Patients Using Microneurography: Study Protocol for a Mechanistic Proof-of-Concept Trial

Introduction: Sodium-glucose co-transporter 2 inhibitors (SGLT2is) have been shown to provide effective cardiorenal protection, reducing mortality in conditions such as heart failure and chronic kidney disease. While several mechanisms have been identified, recent research has shed light on the drug’s ability to attenuate sympathetic nervous system (SNS) activity. Controversy exists on whether this is due to the extra-renal effects of the drug, or simply due to its renoprotective effects. However, recent trials have highlighted the persistent efficacy of SGLT2i despite declining renal function. Therefore, investigating the ability of SGLT2i to attenuate the SNS independently of the kidney could lead to more insight into its mechanism of action. So far, there has been limited research done on investigating the extra-renal effects of SGLT2i in human subjects on dialysis where the glycosuric renal effects of SGLT2i are negligible. This current study therefore aims to investigate the effects of SGLT2i on the SNS in anuric haemodialysis patients. Methods: We developed a protocol for a mechanistic study to investigate the extra-renal effects of SGLT2i on the SNS. The study will be an investigator-led, open-label, prospective study involving 20 adult (aged ≥18 years) haemodialysis patients with a residual urine output of ≤250 mL/day. Participants will be administered empagliflozin 25 mg/day for 6 weeks. Baseline SNS activity will be measured before and after administration by microneurography to assess central SNS outflow. Secondary outcomes such as changes from baseline in SNS stressor response, heart rate variability, and endothelial function will also be examined. We hypothesize that the use of empagliflozin will result in reduced sympathetic drive in anuric haemodialysis patients. Discussion: This will be the first study evaluating the effects of SGLT2i on the SNS in haemodialysis subjects. This study aims to enhance our understanding of the potential role of SGLT2i-induced SNS reduction in the setting of markedly reduced renal function. The study has received ethics approval from the Royal Perth Hospital Human Research Ethics Committee (RGS0000003840) (Australian New Zealand Clinical Trials Registry [ANZCTR] ID: ACTRN12623001237673).

Service Quality Perceived by Athletes: The Case of Local Government Youth Centre

Meeting the needs in social life is given to local governments by the state. Local governments are responsible for meeting the social needs of individuals. Today, youth center areas are built by local governments to meet the social needs of young people and to create social areas. These are areas opened by local governments to protect the mental and physical health of all young people, to provide socio -cultural support, to contribute to the education of young people in line with their interests and to develop their skills. Athletes mostly use these areas for their physical development. These explanations and expressions, in our research, athletes local administrations youth in the centers perceived service of the quality examination is intended. In our research, we used a 10-question personal information forum (Gender, Educational Status, Branch, Monthly Income Status, Age, Your Mother's Educational Status, Your Father's Educational Status, Your Mother's Profession, Your Father's Profession) created by the researchers. The "Perceived Service Quality Scale in Youth Centers" , whose validity and reliability study was conducted by Polat et al. (2013), consisting of 23 items and a 5-point Likert type consisting of three sub-dimensions ( Physical Environment Quality , Interaction Quality, Output Quality ) , was used. The sample of the research consists of 349 (n=145 Female, n=204 Male) volunteer athletes who are actively involved in three different sports branches (n=177 Athletics, n=116 Table Tennis, n=116 Cycling). The data of the research, which was designed as an analytical cross-sectional type, was collected face to face after receiving approval from the Siirt University Social Sciences and Humanities Research Ethics Committee. The data obtained in the research were evaluated in the SPSS 25.0 package program. As a result of the normality analysis of the scale, it was seen that the significance values were greater than 0.05 and it was decided to use non-parametric analyzes in the analysis. In our research, Kruskal Wallis H Test and Man Witney U Test were applied. In the statistical analysis, there was a statistically significant difference in the variables of gender, education level, monthly income level, your mother's education level, your father's education level and the sub-dimensions of the perceived service quality scale in youth centers and the scale general scores. It was observed that there was no statistical difference in the sub-dimensions of the scale of perceived service quality in youth centers and the overall scores of the scale with the variables of profession, your father's profession. As a results;In line with the findings obtained in our research, athletes local administrations youth in the centers perceived service of the quality mom and father education status , gender , education status , monthly income status with statistical aspect difference it shows detection has been made .

Effects of photobiomodulation therapy associated with motor control exercise for chronic non-specific low back pain: protocol for a randomised placebo-controlled trial

Photobiomodulation therapy (PBMT), as an adjunct therapy to exercise, can reduce pain in musculoskeletal disorders. In addition, PBMT associated with exercise decreases fatigue, accelerates muscle recovery and enhances performance and...