Cooperative Research Research Articles

Status and prospect of esophageal cancer screening

Esophageal cancer is one of the global public health problems, which is a serious threat to life and health. Screening is not only an important main measures to reduce the incidence and mortality of esophageal cancer, but also an effective strategy for early prevention and early treatment. There are significant differences in the screening status of esophageal adenocarcinoma and esophageal squamous cell carcinoma cancer between China and abroad. Internationally, there are several guidelines for screening and monitoring of Barrett's esophagus and esophageal adenocarcinoma, but most guidelines do not recommend screening in the general population. The primary screening by sponge ball then endoscopic diagnosis is a new focus. In China, the screening of esophageal cancer and its precancerous lesions is mainly esophageal squamous cell carcinoma, which has been relatively mature and gradually transformed from population screening to opportunistic screening. However, due to the high cost, high technical difficulty and certain invasiveness, it is difficult to popularize and be applied widely; and the canceration rate of precancerous lesions is low, so it is very important to control the cost of screening and scientific follow-up. Moreover, high-risk population should raise their awareness of cancer prevention, actively take primary prevention and the initiative to participate in screening. About medicine institutions, it is urgent to improve the awareness and capacity of early screening. The multi-disciplinary research cooperation, minimally invasive, simple and economical screening methods and multi-omics biomarkers are still explored to detect and concentrate high-risk populations, which will help to optimize screening programs of esophageal cancer and further reduce the incidence and mortality of esophageal cancer.

Inventory & Analysis of Minor Concrete Infrastructure for the City and County of Denver

The City and County of Denver (CCD) and the University of Colorado Denver (UCD) have been involved in cooperative research since 1997. Although a variety of projects have been completed, the main deliverable has been a comprehensive Geographic Information System (GIS) database containing both major and minor infrastructure. Major infrastructure included assets such as bridges and streets, while minor infrastructure includes assets of alleys and street subsystems, which include curbs, gutters, inlets, sidewalks, driveways, crosspans, and curb ramps. This paper presents the equipment and methodology used for the inventory and analysis summary of CCD’s concrete curbs, gutter pans, and alleys.

A long and fruitful cooperation in atmospheric aerosol research between Cuba and Spain

A long and fruitful cooperation in atmospheric aerosol research between Cuba and Spain

Co-operative and mutual enterprises research

Co-operative and mutual enterprises research

Time's Sublimest Target: Practices of Forgetting in HCI and CSCW

In our contemporary moment, there exists a hegemonic design practice and a general social desire to retain information. With the help of sociotechnical platforms and other contemporary technologies, information has changed its temporal and spatial boundaries, creating unbounded, algorithmic, and emergent forms of retention. The consequences of such retention are numerous, ranging from an overabundance of autobiographical information that cannot be fully understood by the individual to the improper use and economization of such information by state and corporation alike. Within this context, this paper investigates a counter-hegemonic practice of forgetting, specifically from the perspective of human-computer interaction and computer-supported cooperative work research, with additional insight drawn from adjacent fields. In doing so, we present forgetting as a significant area of research with HCI and CSCW, a burgeoning and contradictory space that may offer solutions to issues we face within a moment of persistence by default. This paper also explores potential directions for future research and design on forgetting in HCI and CSCW through an investigation of an art piece by Chinese artist Song Dong.

Rural-urban disparity in survival and use of PCI in patients who develop STEMI while hospitalized for a non-cardiac condition.

The development of ST-segment elevation myocardial infarction (STEMI) in patients hospitalized for non-cardiac indications carries a high mortality rate. Determine the impact of rural vs. urban hospital location and hospital percutaneous coronary intervention (PCI) volumes on clinical outcomes. The New York Statewide Planning and Research Cooperative System database was queried for STEMI claims from 2011 to 2018. The 2010 Rural-Urban Commuting Area classification scheme was used to stratify hospitals as urban or rural. 64960 STEMI patients were identified from 231 hospitals with 2880 (4.4%) being classified as inpatient STEMI (IPS). IPS patients were older (73.5 ± 13.3 years vs 64.6 ± 14.2 years; p < .0001) and more frequently female (49.3% vs 33.1%; p < .0001), had more comorbidities, were less likely to receive PCI (13.1% vs 69.4%; p < .0001), and had higher 1-year mortality (59.6% vs 16.4%; p < .0001) than outpatient STEMI (OPS). IPS that occurred in rural hospitals were less often treated with PCI (3.8% vs 13.8%; p < 0.01) and had higher one-year mortality (68.6% vs 58.9%; p < 0.01) than those occurring in urban hospitals. Similar results were observed when hospitals were divided into rural vs suburban vs urban based on the 2013 National Center for Health Statistics Urban-Rural Classification Scheme for Counties. Patients with IPS admitted to low-volume PCI centers were significantly less likely to receive PCI and had higher one-year mortality, after adjustment for demographics and comorbidities, compared to those admitted to high-volume PCI centers. IPS treated at rural hospitals and/or low-volume PCI centers were less likely to be treated with PCI and had higher one-year mortality rates. The development of ST-Segment Elevation Myocardial Infarction (STEMI) in patients hospitalized for non-cardiac indications carries a high mortality rate. Using a large retrospective cohort study, we investigated the impact of hospital location and PCI volume on outcomes in inpatient STEMI (IPS). Patients with IPS were generally older, more frequently female, and had more comorbidities than those with outpatient STEMI. After adjustment for demographics and comorbidities, those with IPS admitted to rural and/or low-volume PCI centers were less likely to receive PCI and experienced higher one-year mortality rates.

Companion animal and equine clinical research: a Nordic perspective.

The societal value of cats, dogs and horses is high, and the companion and sport animal health care sector is growing. Clinical research concerning cats, dogs and horses is crucial for the development of evidence-based medical care that benefits animals and their owners, and has implications for human and environmental health from a One Health perspective. Basic information on companion animal and equine research enables more directed measures to improve conditions for research within the area. The aim of the present study was to describe Nordic companion animal and equine clinical research from 2010 to 2019, including bibliometrics, human resources and funding. There were 2 042 published research publications originating from Nordic countries on cats (n = 282), dogs (n = 1 086), and horses (n = 781) from 2010 to 2019. The majority (83%) of the publications came from the four Nordic universities with veterinary programs. Seven percent of the publications were collaborations between two or more Nordic universities. Approximately 18% of the PhD theses (178 out of 970) from veterinary faculties or corresponding units concerned these species, most of them dogs (n = 86), followed by horses (n = 64), cats (n = 15) or a combination of these species (n = 13). The scientific areas cardiology, infectious diseases, reproduction, and surgery were prominent for all three species. A large proportion of grants were received from small- to medium-sized funding bodies, mainly funding running costs and only to a limited degree salaries. During 2010-2019, costs for veterinary and other services for cats and dogs steadily increased. The growth of the veterinary healthcare sector was not reflected in an increasing number of clinical research publications, for which no increase was seen after 2014. Despite a high societal value of the species, veterinary clinical research on sports and companion animals has not increased, in contrast to the veterinary healthcare sector. Activities stimulating the research area, e.g. funding bodies enabling coverage of salaries, are needed. The development of Nordic veterinary clinical care may benefit from strengthened research cooperation between countries.

Visualization analysis of high voltage pulsed electric field based on Web of Science database

To deeply understand the development status and research hotspots of high voltage pulsed electric field (HVPEF) technology, this paper takes the Web of Science (WOS) core collection Science Citation Index Expanded (SCI-EXPANDED) database as the literature source, and sets `high voltage pulsed electric field' as the keyword search. The collected 3041 articles (January 1, 1990–December 31, 2022) were used as the research object. CiteSpace and VOSviewer software were used to visually analyze the number of publications, citations, authors, institutions, journals, countries, disciplines, and keywords, and draw a visual map to explore the development context and content evolution of the technology on a global scale. It is found that the HVPEF technology is in a stage of rapid development, and the number of published papers and citations of relevant literature is on the rise. This field has been centered on China and the United States, forming a closely cooperative academic research network. There is also a close cooperative relationship between different authors and institutions. In addition, the research on HVPEF is mainly applied to physics, plasma, etc., but food, materials, and other disciplines are also involved. The research content extends from the PEF itself to cells, microorganisms, etc., and gradually from principle-based research to the use of technology to achieve the purpose. In recent years, the research on the extraction of active compounds assisted by PEF is increasing, which is likely to become one of the future research hotspots in this field. In summary, the HVPEF is receiving more and more attention, and has a very good research and application prospect.

China-UK Global Health Collaboration Project on Strengthening Public Health Capacity in Sierra Leone.

Since 2016, the Chinese Center for Disease Control and Prevention has continued to conduct project to assist Sierra Leone in improving its public health capacity and building a laboratory for bacteriological and parasitic diseases. Firstly, we can understand the epidemiological characteristics, etiological characteristics and drug resistance of important infectious diseases in Africa through this project, and provide services and guarantees for the construction of the Belt and Road Initiative. Secondly, the project is to carry out scientific research cooperation on the monitoring and detection capacity of major infectious diseases, biosecurity, and prevention and control technologies for important infectious diseases. Thirdly, in order to implement the concept of "building a community with a shared future for mankind", it is important to improve the capacity of Sierra Leone and West Africa to prevent and control infectious diseases, maintain global health security, and participate in global health governance. This article reviews the implementation of the project, and summarizes the experience and shortcomings, in order to help readers achieve better results in future project practice.

The Research of Relationship between Evolution of Science Research Cooperation Mode and Innovation Based on Collaboration Network—A Case Study of Ocean University of China

The Research of Relationship between Evolution of Science Research Cooperation Mode and Innovation Based on Collaboration Network—A Case Study of Ocean University of China

Collaborative Linkages Among Universities, Industry, and Research: Empowering Enterprises in Free Trade Zones for High-Quality Advancement

Against the backdrop of current economic globalization and regional economic integration, the construction of pilot free trade zones and free trade ports has become an important strategic measure for China to promote high-quality economic development and enhance international competitiveness. As an important base for knowledge innovation and talent cultivation, universities can provide strong intellectual support and technical support for the high-quality development of free trade zones and free trade port enterprises through industry university research cooperation. This article delves into the significance of university industry academia research cooperation for the high-quality development of enterprises in pilot free trade zones and free trade ports, analyzes the current problems, and proposes forward-looking, targeted, and actionable countermeasures and suggestions.

신경기술의 발전과 의료기기 규제의 국제표준화

With the recent growth of the electroceuticals and digital therapeutics industry, licensing, new health technology assessment, and determination of health insurance fees have emerged as important regulatory issues in Korea. Although various neurotechnology-based medical devices have already been released, research on the latest neurolotechnologies such as BCI is underway, and the regulatory standards for them are unclear, as well as the benefits and risks of the technology. As a result, the need for international standardization and global regulatory harmonization will increase, along with the demand for standardization in technical standards, safety verification, and full cycle risk management. This article deals with the characteristics of medical devices to which the latest neurotechnology is applied, its impact on regulation, and related international discussions, as well as the implications of international standards as soft laws, and reviews international standards for medical devices. Based on these discussions, the trend of international standardization of neurotechnology-based medical devices was reviewed and its implications were derived. In order to resolve the uncertainty of regulations on neurotechnology-based medical devices and to regulate them appropriately, flexible responses are needed on the basis of global regulatory harmonization such as international standardization. Additionally, efforts to preempt international standards in neurotechnology-based medical devices are required because international standards are accepted as domestic norms through national standards and directly affect regulations by individual domestic laws. With the rapid development of BCI technology and technology convergence, related industries will grow further in the future, and international discussions on the regulation of neurotechnology will become more active. Through these international discussions, consideration and regulatory principles for the benefits and risks of neurotechnology should be prepared, and they should be embodied through international standards and domestic norms. In this process, regulatory agencies should lead active participation and cooperation of companies and researchers.

On Problems of Establishing State Sovereignty over Antarctic Territories: China’s International Legal Position

INTRODUCTION. The Antarctic region is unique in terms of organizing effective management by a large number of states at the same time. For this purpose, the Antarctic Treaty was concluded, which made it possible to prevent the conflicts. Nevertheless, not long ago the concept of territorial division of this region has been actively discussed. China, being one of the most economic rapidly developing states, which implies its interest in strengthening its influence in the Antarctic region, also actively participates in solving the problems related to the legal regulation of the Antarctic region. The purpose of the article is to determine the position of China in relation to the activities in the Antarctic region in general, as well as, establishing state sovereignty over the territories of Antarctica.MATERIALS AND METHODS. The research uses various documents of international legal nature, including international treaties, doctrinal sources and national legislation of foreign countries. The research is carried out with the use of general scientific and special scientific methods. RESEARCH RESULTS. The article provides a comprehensive analysis of the Chinese international legal doctrine concerning the establishment of state sovereignty over the Antarctic territories and makes assumptions on further development of China in the Antarctic region. The main directions of China’s activity, including related to national security and extraction of natural resources, were analyzed. The provisions of the “White Book of China on Antarctica” were also analyzed. In addition, China’s initiatives concerning the establishment of Marine Protected Areas, Specially Managed Areas were examined. The question of whether China has its own Antarctic policy was answered.DISCUSSION AND CONCLUSIONS. The examination of the problems of establishing state sovereignty over the Antarctic territories from the point of view of China allows us to conclude that at the moment China does not have a developed Antarctic policy and is at the stage of its formation. China’s attempts to influence the Antarctic management system began in 2005, when the establishment of the Specially Managed Areas was suggested. Since then, China’s influence has continued to grow. China acted and continues to act in accordance with the Antarctic Treaty System, which indicates that China is not willing to change the system of management of the region to the system of territorial division. At the moment, China’s interests in Antarctica are characterized by an increased focus on scientific research, environmental protection and international cooperation. China’s influence in the region is expected to increase.

Assessing Results of University Research Activities: Indicators of Openness in Rankings

Open access to scientific results and research data becomes an engine for the successful development of modern science. The article examines popular rankings of world universities: the CWTS Leiden Ranking, the Times Higher Education World University Rankings (THE Rankings), the QS World University Rankings (QS), the SCImago Institutions Rankings (SIR) and the Academic Ranking of World Universities (ARWU). The objective of the research was to study the ranking methodologies in the ratings under consideration and to determine the place of the openness criteria in them. A comparative analysis of world’s and Russia’s top universities in rankings is provided. The author has made an assessment of the significance of openness indicators in the world rankings, on the basis of which it has been concluded that only two world rankings pay due attention to these ranking criteria. Of those considered, only the evaluation methodologies of the CWTS Leiden Ranking and the SCImago Institutions Rankings take into account a quantitative analysis of open access publications and altmetric impact indicators. The rest of the considered rankings focus mainly on standard bibliometric indicators from different blocks related to the assessment of education, research, academic impact and international cooperation. Thus, in 2019–2022, the University College London (UK) was the top university in the CWTS Leiden Ranking in terms of the share of open access publications (90.8%) and Moscow Institute of Physics and Technology was ranked the first among Russian universities (66.6%).

The New Face of Thinking in Education: Bibliometric Map of Design Thinking

In the age of information and technology, students are expected to develop skills such as critical thinking, problem solving, and creative solutions. Design thinking stands out as an effective approach to develop these skills in education. Design thinking is a method that encourages empathy, creativity, collaboration, and user-oriented solutions and increases student participation in education. As educators are expected to continue applying and researching this approach, this study aims to analyze the current status and development trends of design thinking in the field of education, to reveal the research dynamics, cooperation networks, and impact areas in the field. The bibliometric analysis method was used to provide a holistic perspective in a data-based, numerical, and objective way. Within the scope of the research, the studies published in the ‘Education-Educational Research’ category with the keyword ‘design thinking’ in Web of Science between 2010-2024 were analysed. The bibliometric analysis of research on design thinking in education (DOD) between 2010 and 2024 shows that this field has become an essential subject of study. In these studies led by the USA and China, themes such as creativity, higher education, and experiential learning come to the fore. The concentration of studies in specific journals and by a limited number of prolific authors creates opportunities for new researchers. Citation data emphasise the impact and importance of TOD research on educational practices and outcomes. In addition, the findings of the research may be useful in developing new perspectives and approaches for future studies on design thinking and in examining the existing literature and previous studies from a broader perspective.

Ethnicity and Representation

AbstractThose Germans who remained in Hungary after the Second World War faced complex political, economic, and social difficulties. In cultural terms, the diverse self-definitions of the Germans living in Hungary at that time precluded national cohesion, despite the use by the authorities of the unifying definition “German.” This national minority was bound together primarily by shared trauma. Individuals and communities alike were searching for their place amidst the changed circumstances, and it was the umbrella organization known as the Democratic Association of Germans in Hungary (Magyarországi Németek Demokratikus Szövetsége) that sought to bring them together. It was not until the 1970s that the association began to professionalize its activities and to conduct ethnographic research in cooperation with qualified specialists. During this process, the village of Harta, which was already famous for its folk art, came to their attention. It was specifically the economic potential of this settlement in Bács-Kiskun County, and its character as an ethnic and confessional enclave, that laid the foundations for the uniform objects and motifs of this local center of furniture painting. After the Second World War, the county administration's cultural policy was relatively accepting of the furniture-making tradition here, and the local intelligentsia showed a supportive attitude towards the settlement's German heritage. In the 1970s, there was still a furniture painter living in Harta, who won the most prestigious folk-art award, regularly participated in exhibitions and gala events, and even produced painted furniture in the cooperative's subsidiary branch at the initiative of the local council president. This ensured that painted furniture from Harta came to represent not only the traditionalist aspirations of the German Association, but also national cultural policy. Harta furniture emerged as the most iconic style of minority painted furniture and as the shared heritage of the German community in Hungary.

A Literature Analysis of Coastal Zone Carbon Cycle Research Based on Knowledge Graphs

This paper conducts a comprehensive literature analysis of coastal zone carbon cycle research utilizing CiteSpace software to visualize the intellectual structure and evolution of the field from 1999 to 2025. The study categorizes various coastal ecosystems into 12 groups, examining 12,460 documents sourced from the Web of Science databases. The analysis reveals publication dynamics, identifies key publication types, and maps the research topics and cooperation network of participating countries, with a particular focus on the United States and China as leading contributors. The paper also highlights influential authors and thematic clusters within the literature, such as dissolved organic matter, blue carbon, and ocean acidification. The analysis provides a systematic overview of the coastal carbon cycle research field, informing future research directions and policy decisions related to coastal carbon management and climate change mitigation strategies. The study concludes that while significant advancements have been made, there are still considerable gaps and challenges that need to be addressed, emphasizing the potential of coastal ecosystems in mitigating climate change and promoting sustainable development.

Agricultural Wastewater Reuse as a Circular Economy Model: Future Scenarios Considering Reg. (EU) 2020/741

The water industry is facing challenges because of population increases and the resulting development of agricultural operations. Alternative resources that balance the environment, the economy, and society while lessening the strain on limited water supplies will need to be adopted by farmers. One possibility addressing this dilemma is wastewater reuse. The adoption of Reg. (EU) 2020/741 necessitates a paradigm change by moving away from the “fit-for-all” strategy and toward the “fit-for-purpose” approach, which is now regarded as the foundation of the reuse supply chain. However, despite progress, appropriate rules that clearly and concisely outline the procedures to be followed are still needed. Thus, to establish an interdisciplinary and cooperative research agenda, this study tackles the potential and forces behind change by concentrating on tactics for long-term fixes. The need to look at consumer and farmer acceptability as well as the overall environmental advantages of carbon footprint reduction and wastewater fertigation are interesting research avenues. Nutrient-rich streams in agriculture may increase carbon absorption and reduce greenhouse gas emissions from the soil while simultaneously serving as a fertilizer substitute. The literature suggests that additional research is necessary to fully explore the significant economic potential.

SCIENTIFIC AND RESEARCH COOPERATION BETWEEN UNIVERSITIES AND BUSINESS: OPTIMIZATION OF PARTNER SEARCH WAYS

Scientific, technical and innovative cooperation between universities and business is actualized by two circumstances: 1) the need to transform the domestic economy towards increasing its science-intensiveness and 2) the growing interest of higher education institutions in such cooperation due to the desire to receive additional funding, both through the fulfillment of research orders from corporations and through the formulaic calculation of budget allocations, which depend on the volume of scientific, technical and consulting services provided. There are various models of scientific and research cooperation between universities and business: open science and open innovation, the model of the national innovation system, the triple helix model, each of which proves the need for such collaboration. However, the practical aspect of building effective cooperation between universities and business in scientific, research and innovation activities is still poorly studied. Economically developed countries pay considerable attention to studying the issues of joint scientific research between universities and the business sector. The summary of the reports of sociological research of EU countries among the heads of universities and business structures in 2011-2012, 2016-2018, 2020-2021 made it possible to summarize both the reasons for the interest of universities and business in joint research and development and the obstacles to their effective cooperation. It was found that in Ukraine, research cooperation between higher education institutions and the business sector is not widespread, although it has great potential. The main barriers to such cooperation were identified, among which the problem of initiating research cooperation is highlighted. Teachers do not know how to find a partner for scientific and research cooperation. An algorithm for preparing a university for research partnership with business is proposed, which includes seven main stages, the procedure for their implementation and a set of measures for each stage. Using the proposed approach will help universities optimize the organization of joint R&amp;D with business.

Bridging bench to bedside: The evolution and impact of translational research in oncology. The experience of the Gruppo Oncologico Italiano di Ricerca Clinica (GOIRC).

The Gruppo Oncologico Italiano di Ricerca Clinica (GOIRC) is Italy's first cooperative oncology research group, evolving to conduct academic clinical trials since 1985. With 167 publications and collaborations with national and international partners, GOIRC has significantly impacted clinical practices. The group emphasizes training and has developed robust internal standard operative procedures (SOPs) to enhance data quality. GOIRC is poised to tackle future challenges in translational research, focusing on innovative trial designs, precision medicine, and leveraging different laboratory resources across its 42 units.