The 24th International ACM SIGACCESS Conference on Computers and Accessibility (ASSETS 2022), was held in Athens, Greece between October 23rd to 26th, 2022. ASSETS continues to be the premier computing research conference exploring the design, evaluation, and use of computing and information technologies with and for people with disabilities and older adults. ASSETS 2022 was held in-person for the first time since 2019. Due to the continuing COVID-19 pandemic, a lightweight online component for virtual conference attendees was conducted as well. In order to support both accessibility and inclusivity, and balancing technical infrastructure and time-zone constraints, all presentations were also pre-recorded and captioned to support both virtual and in-person conference attendees. There were additional creative opportunities for hybrid connections and socializing across modalities, including online trivia and roundtable social networking events. We acknowledge that future ASSETS organizing committees will need to make their own decisions about the length and format of the conference, and so the decision to have an in-person with light-weight online component is not a permanent decision. Overall, ASSETS 2022 had 161 in-person and 146 virtual attendees from 38 countries and 6 continents. For the first time, we hosted 5 virtual workshops, with 94 workshop-only attendees.