In steel frame-tube structures (SFTSs) the application of flexural beam is not suitable for the beam with span-to-depth ratio lower than five because the plastic hinges at beam-ends can not be developed properly. This can lead to lower ductility and energy dissipation capacity of the SFTS. To address this problem, a replaceable shear link, acting as a ductile fuse at the mid length of deep beams, is proposed. SFTS with replaceable shear links (SFTS-RSLs) dissipate seismic energy through shear deformation of the link. In order to evaluate this proposal, buildings were designed to compare the seismic performance of SFTS-RSLs and SFTSs. Several sub-structures were selected from the design buildings and finite element models (FEMs) were established to study their hysteretic behavior. Static pushover and dynamic analyses were undertaken in comparing seismic performance of the FEMs for each building. The results indicated that the SFTS-RSL and SFTS had similar initial lateral stiffness. Compared with SFTS, SFTS-RSL had lower yield strength and maximum strength, but higher ductility and energy dissipation capacity. During earthquakes, SFTS-RSL had lower interstory drift, maximum base shear force and story shear force compared with the SFTS. Placing a shear link at the beam mid-span did not increase shear lag effects for the structure. The SFTS-RSL concentrates plasticity on the shear link. Other structural components remain elastic during seismic loading. It is expected that the SFTS-RSL will be a reliable dual resistant system. It offers the benefit of being able to repair the structure by replacing damaged shear links after earthquakes.