Renal Pharmacology Research Articles

DRUG UTILIZATION PATTERN AND ADVERSE DRUG REACTION MONITORING IN URINARY TRACT INFECTION PATIENTS IN A TERTIARY CARE HOSPITAL

Background : Urinary tract infection is a key public health issue causing morbidity, especially in women population. This problem is further aggravated in pregnant women. Aims: This study was designed to evaluate the drug prescribing behaviour and adverse drug reaction monitoring in urinary tract infection patients in a tertiary care hospital. Materials and Methods: The present study was prospective, observational and carried out for four months, and done to assess the drug utilization pattern, adverse drug reactions (ADRs) and to identify the bacterial pathogens associated with UTI and their susceptibility to antibiotics. Results: A total of 327 female patients were evaluated, out of which 248 (75.84%) cases were symptomatic. The study reflected maximum of 50.46% UTI in the age group 21-30 years. Pathogens isolated after a urine culture were of both Gram positive 131 (40.07%) and Gram negative 196 (59.93%) type. The maximum incidence (45.80 %) occurred in last trimester of pregnancy. The most frequently prescribed antibiotic to the pregnant patients in our study was Nitrofurantoin, whereas Amoxicillin with Clavulanic acid was most frequently used in non pregnant cases. Most common ADRs reported with almost all classes of antibiotics was nausea and vomiting followed by vaginal irritation, skin rash and photosensitivity. Conclusion: To ensure appropriate therapy, current knowledge of the pathogenic organism and their antibiotic susceptibility pattern is mandatory, especially in cases of UTI with pregnancy. Keywords: Drug utilization pattern,Adverse Drug Reactions, Urinary Tract Infection, Renal Pharmacology

Renal safety pharmacology: Characterization of a non-rodent model with water loading using a positive control agent

Renal safety pharmacology: Characterization of a non-rodent model with water loading using a positive control agent

What is the purpose of launching the World Journal of Nephrology?

The launch of the World Journal of Nephrology (WJN) has distinct purposes. Its main purpose is to incorporate the fields of diabetes, hypertension, urology, cardiology and neurology, which are related to kidney disease, and to make all of our readers, contributors and allied health professionals feel at home with the WJN. The WJN aims to rapidly report new theories, methods and techniques for prevention, diagnosis, treatment, rehabilitation and nursing skill in the field of nephrology. The WJN will cover diagnostic imaging, disorders of kidney development, renal obstruction, atrophy and regeneration, kidney tumors, renal pharmacology and therapy, renal replacement therapies including transplantation, and Chinese herbal medicine. The WJN issues will include an editorial, frontier, invited review of articles and commentaries in addition to original articles submitted. The WJN will solicit articles from investigators in areas of diabetes and hypertension, and high priority will be given to those articles with an emphasis on the prevention of dialysis. Final decision for publication will be based on the merit of the article, language and lucidity.

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

D.F. Geary and F. Schaefer: Comprehensive paediatric nephrology

This is an impressive textbook (1,099 pages) on paediatric nephrology from more than 120 contributors from varied specialities with a thorough international perspective; in fact, the two editors are from Toronto and Heidelberg, Germany, respectively, and the co-authors come from all over the world. The 14 sections (tools of investigation, disorders of renal development, disorders of glomerular function, specific glomerular diseases, the kidney and systemic diseases, renal tubular disorders, tubulointestinal disease, urinary tract disorders, acute renal failure, hypertension, chronic kidney disease, renal replacement therapy, renal transplantation and renal pharmacology) cover in a concise and focused fashion almost every clinical condition. Comprehensive information delivers valuable insights, allowing informed and efficient decisions and easy access guidance. The index is of excellent quality, and the bibliography is extensive and covers the most important publications. Clinical skills, diagnostic techniques, understanding pathogenesis and scientific advances, excellent imaging with multiple figures and schematic drawings (delivered also in a bonus CD ROM) and remarkable references to evidence based medicine are the backbones of the different chapters. An excellent chapter on traditional and complementary medicine is worth mentioning as it demonstrates the author’s unbiased approach and their interest in all facets of renal problems. This book is the ideal companion for paediatric nephrologists and urologists as well as trainees in nephrology and can be of great value for general paediatricians as a very rapid and informative source of knowledge for day-to-day care of their renal patients.

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics

F. Clinical Renal Pharmacology and Therapeutics