Remote Function Research Articles

A Barton nitrite ester-type remote functionalization and cyclization of N-nitrosobenzamides

The preparation of benzo[d][1,2]oxazin-1-ones from N-ethyl-N-nitrosobenzamides was established via a visible-light-driven Barton reaction and subsequent nucleophilic cyclization.

Progress in catalytic asymmetric α-functionalization of vinylogous nucleophilic species

This review summarizes a view of the advances in the catalytic asymmetric α-functionalization of vinylogous nucleophilic species, the content of which is categorized based on the type of vinylogous donor.

ТЕНДЕНЦИИ РАЗВИТИЯ ПРИБОРОВ УЧЁТА ЭЛЕКТРОЭНЕРГИИ

The trends in the development of electricity metering devices, new generation meters, the introduction of "smart" electricity meters equipped with a remote control function are considered

Rhodium‐Catalyzed Remote Borylation of Alkynes and Vinylboronates

AbstractRemote functionalization involving a fascinating chain‐walking process has emerged as a powerful strategy for the rapid access to value‐added functional molecules from readily available feedstocks. However, the scope of current methods is predominantly limited to mono‐ and di‐substituted alkenes. The remote functionalization of multi‐ and heteroatom‐substituted alkenes is challenging, and the use of alkynes in the chain walking is unexplored. We herein report a rhodium catalyzed remote borylation of internal alkynes, offering an unprecedented reaction mode of alkynes for the preparation of synthetically valuable 1,n‐diboronates. The regioselective distal migratory hydroboration of sterically hindered tri‐ and tetra‐substituted vinylboronates is also demonstrated to furnish various multi‐boronic esters. Synthetic utilities are highlighted through the selective manipulation of the two boryl groups in products such as the regioselective cross coupling, oxidation, and amination.

Rhodium-Catalyzed Remote Borylation of Alkynes and Vinylboronates.

Remote functionalization involving a fascinating chain-walking process has emerged as a powerful strategy for the rapid access to value-added functional molecules from readily available feedstocks. However, the scope of current methods is predominantly limited to mono- and di-substituted alkenes. The remote functionalization of multi- and heteroatom-substituted alkenes is challenging, and the use of alkynes in the chain walking is unexplored. We herein report a rhodium catalyzed remote borylation of internal alkynes, offering an unprecedented reaction mode of alkynes for the preparation of synthetically valuable 1,n-diboronates. The regioselective distal migratory hydroboration of sterically hindered tri- and tetra-substituted vinylboronates is also demonstrated to furnish various multi-boronic esters. Synthetic utilities are highlighted through the selective manipulation of the two boryl groups in products such as the regioselective cross coupling, oxidation, and amination.

Study on the automatic optimization design of the cross-sectional layout of an umbilical with layers based on the GA-GLM

Marine umbilical provides the remote control function for offshore oil and gas exploitation, which is usually integrated by different functional components that vary widely in their mechanical properties. Under the action of external load, unreasonable cross-sectional layouts may lead to large cross-sectional deformation and contact pressure between components thus affecting the service life of an umbilical. Therefore, how to design the cross-sectional layout is a very necessary research work in order to improve service life of the umbilical to withstand various loads during operation. At present, the research on the cross-sectional layout of an umbilical is not sufficient, and there is no standardized design method in the design specification. Considering the mechanical and geometrical properties as the quantitative design objectives, the mathematical optimization model of the cross-sectional layout of an umbilical is proposed. Meanwhile, the layering strategy is introduced because of the processing and manufacturing factors.Then, the genetic algorithm (GA) with good global search performance and the generalized Lagrange multiplier (GLM) with fast convergence speed are combined to solve the above model. Finally, taking an umbilical as an example, the optimal cross-sectional layout is obtained and the effectiveness of the algorithm is verified by the numerical simulation. The results show that the optimization method proposed in this paper can quickly obtain the optimal design cross-sectional layout, and supply a specific way for the fast design of an umbilical, which has the certain engineering application value.

ZnO/Cu2O heterojunction integrated fiber-optic biosensor for remote detection of cysteine

Indium tin oxide, semiconductor nanomaterial ZnO, and Cu2O were first loaded on the surface of the optical fiber to form an optical fiber probe. Large-volume macroscopic spatial light is replaced by an optical fiber path, and remote light injection is implemented. Based on the optical fiber probe, a photoelectrochemical biosensor was constructed and remote detection of cysteine was realized. In this tiny device, the optical fiber probe not only acts as a working electrode to react with the analyte but also directs the light exactly where it is needed. Simultaneously, the electrochemical behavior of cysteine on the surface of the working electrode is dominated by diffusion-control, which provides strong support for quantitative detection. Then, under the bias potential of 0 V, the linear range of the fiber-optic-based cysteine biosensor was 0.01∼1 μM, the regression coefficient (R2) value was 0.9943. In spiked synthetic urine, the detection of cysteine was also realized by the integrated biosensor. Moreover, benefiting from the low optical fiber loss, the new structure also possesses a unique remote detection function. This work confirms that photoelectrochemical biosensors can be integrated via optical fibers and retain comparable sensing performance. Based on this property, different materials can also be loaded on the surface of the optical fiber for remote detection of other analytes. It is expected to facilitate the research on fiber-optic-based integrated biosensors and show application prospects in diverse fields such as biochemical analysis and disease diagnosis.

Agri-Environment Atmospheric Real-Time Monitoring Technology Based on Drone and Light Scattering

The emission of particulate matter (PM) from agricultural activities, such as concentrated animal feeding, straw combustion, and mechanized harvest, is a hot issue in the sustainable development of agriculture, which has attracted more and more attention from government departments and researchers. However, the research on the transport of particulate matter in the agri-environment still lacks flexible and efficient measurement methods to obtain real-time and accurate spatial distribution data. The objective of our study is to produce a new intelligent platform for agri-environment atmospheric monitoring with high mobility, temporal and spatial resolution, and remote data transmission function to overcome the shortcomings of traditional atmospheric particulate matter monitoring stations, such as small particle size range, immovability, and high cost. Through the light scattering sensor, microcontroller, and wireless data transmission device assembled on the high-mobility drone, the platform could measure the mass concentration of PM2.5, PM10, and TSP at different spatial points in the agri-environment and transmit the measurement data to the receiving device on the ground through three modes: CLOUD, TCP, and UDP. We also developed monitoring software based on the Android platform, which could complete the connection of device and real-time monitoring of measurement data on the ground. Compared with stationary measurement devices, the biggest advantage of our mobile monitoring system is that it has the ability to measure the concentration of TSP and the vertical distribution of PM, which is very important for the research of agricultural environmental particulate matter emission characteristics. After the sensor and communication performance experiments, the sensors had high consistency in the overall change trend, and the communication accuracy rate was high. We carried out a flight measurement comparison experiment at the Wenhua Road Campus of Henan Agricultural University, and the measurement data were highly consistent with the data from the national monitoring stations. We also conducted an agri-environmental atmospheric measurement experiment in Muzhai Village and obtained the vertical distribution data of PM concentration at the nearby measuring point when the harvester was working. The results showed that after the harvester worked for a period of time, the PM2.5, PM10, and TSP concentrations reached the maximum at the altitude of 20 m at the measurement point, which were 80, 198, and 384 μg/m3, respectively, 2.64~3.10 times the particle concentration in the environment before the harvester began to work. Our new platform had high mobility, sensitive reading, and stable communication during the experiment, and had high application value in agricultural environmental monitoring.

Front Cover Picture: Zincate‐Mediated Remote Functionalisation of p‐Iodobenzyl Derivatives Through Metallotropy in 2‐Methyltetrahydrofuran as Key Solvent (Adv. Synth. Catal. 22/2022)

The front cover picture illustrates the 1,5-rearrangement of lithium benzyl(dibutyl)zincate derived from p-iodobenzyl mesylate. This key elementary step is integral to a complex reaction sequence allowing the remote functionalisation of such a derivative with a wide range of aldehydes (see fruits in the tree). As a remote leaving group (here OMs) is required to trigger the chemical event, the release of LiOMs can be seen as a driving force (LiOMs is thus the driver of the boat). Details can be found in the Research Article by Alexandre Vasseur and co-workers (A. Pierret, C. Denhez, P. C. Gros, A. Vasseur, Adv. Synth. Catal. 2022, 364, xxxx–xxxx; DOI: 10.1002/adsc.202200475)

Magnetically‐Assisted 3D Bioprinting of Anisotropic Tissue‐Mimetic Constructs

AbstractRecreating the extracellular matrix organization and cellular patterns of anisotropic tissues in bioengineered constructs remains a significant biofabrication challenge. Magnetically‐assisted 3D bioprinting strategies can be exploited to fabricate biomimetic scaffolding systems, but they fail to provide control over the distribution of magnetic materials incorporated in the bioinks while preserving the fidelity of the designed composites. To overcome this dichotomy, the concepts of magnetically‐ and matrix‐assisted 3D bioprinting are combined here. By allowing low viscosity bioinks to remain uncrosslinked after printing, this approach enables the arrangement of incorporated magnetically‐responsive microfibers without compromising the resolution of printed structures before inducing their solidification. Moreover, the fine design of these magnetic microfillers allows the use of low inorganic contents and weak magnetic field strengths, minimizing the potentially associated risks. This strategy is evaluated for tendon tissue engineering purposes, demonstrating that the synergy between the biochemical and biophysical cues stemming from a tendon‐like anisotropic fibrous microstructure, combined with remote magneto‐mechanical stimulation during in vitro maturation, is effective on directing the fate of the encapsulated human adipose‐derived stem cells toward tenogenic phenotype. In summary, the developed strategy allows the fabrication of anisotropic high‐resolution magnetic composites with remote stimulation functionalities, opening new horizons for tissue engineering applications.

Phosphine oxide directing-group-enabled atroposelective C–H bond acyloxylation via an eight-membered palladacycle intermediate

Herein, we report the first atroposelective C(sp2)–H bond acyloxylation enabled by a phosphine oxide directing group. Uniquely, this transformation is shown to proceed through an eight-membered palladacycle intermediate, as opposed to the kinetically and thermodynamically favored five-membered palladacycle intermediate. Additionally, l-pGlu-OH, a cheap and abundant chiral amino acid derivative, was identified as the best chiral ligand to promote this atroposelective remote CH functionalization reaction.

Exploring nurses' perceptions of the barriers and facilitators that influence acceptance and use of remote visual monitoring technology.

Describe nurses' perceptions of the barriers and facilitators that influence acceptance and use of remote visual monitoring technology. Research has shown remote visual monitoring to be a useful patient safety intervention, yet nurses underutilize the technology. Using a qualitative descriptive study design, we completed a conventional content analysis of focus group feedback from two nurse leader groups and two direct care nurse groups (n = 13 participants) to explore factors influencing nurses' perceptions and utilization of remote visual monitoring. Five main themes were identified: (1) Contextual human factors that impact nurse acceptance; (2) facilitators and barriers related to remote visual monitoring's functionality; (3) nurse leaders' role in maintaining device availability and efficient use; (4) nurse leaders' role in promoting adoption of the technology; and (5) nurse leaders' role in valuing nursing professional judgement. Findings indicate that nurse leaders can play a crucial role in direct care nurses' acceptance and use of remote visual monitoring technology. In an era of limited staffing resources, remote visual monitoring has the potential to increase patient safety and decrease workload demands. Nurse leaders should identify barriers and facilitators to their nursing team's use of remote visual monitoring to promote the acceptance and use of technology that increases patient safety and cost-effectiveness of care.

Interlinkage of a siliconoid with a silsesquioxane: en route to a molecular model system for silicon monoxide

AbstractA new potential model system for silicon monoxide (SiO) is synthesized by the interlinkage of an unsaturated silicon cluster (siliconoid) with a polyhedral silsequioxane cage. Two derivatives with variable linker size are obtained by the corner‐capping reaction of Ph7T7(ONa)3 with a trichlorosilane featuring a remote benzylic chloride functionality and the subsequent nucleophilic substitution of the latter by the anionic hexasilabenzpolarene‐type Si6 siliconoid. Based on the recently proposed heterogeneous cluster model for the SiO structure, the stoichiometry between silicon and oxygen reiterates the suboxidic interface of the nano‐composite in a Si : O ratio of 14 : 12.

Brønsted acid catalyzed remote C6 functionalization of 2,3-disubstituted indoles with β,γ-unsaturated α-ketoester.

A metal-free catalytic approach for the remote C6-functionalization of 2,3-disubstituted indoles has been developed. In the presence of catalytic amounts of Brønsted acid, the β,γ-unsaturated α-ketoesters react with 2,3-disubstituted indoles at the C6 position selectively. Under mild reaction conditions, a range of C6-functionalized indoles were prepared with good yields and excellent regioselectivity. This methodology provides a concise and efficient route for the synthesis of C6-functionalized indole derivatives.

Development of FSM corrosion monitoring system based on Cloud Server

FSM (field signature method) is a new non plug-in on-line monitoring method for pipeline corrosion. The traditional FSM corrosion monitoring equipment is generally a single machine to copy data or collect terminal client wireless transmission data, which is not convenient for data management. In this paper, cloud service is introduced into the monitoring system, and the FSM corrosion monitoring system based on cloud server is developed, which realizes the functions of real-time, online and remote control. The monitoring system can obtain the current status data of the monitored pipeline in real time, and calculate the corrosion parameters of the pipeline according to the data sent back by the measuring device. The system can draw trend diagram and morphology diagram according to the calculated corrosion parameters, display database data tables and relevant charts, and send monitoring information regularly.

Design and Realization of Seeding Quality Monitoring System for Air-Suction Vibrating Disc Type Seed Meter

To improve the seeding qualification rate and stability of the air-suction vibrating disc type seed meter on the rice seedling raising line, in this paper, an improved wireless sensor network node layout optimization algorithm was proposed, and the operation monitoring system of the seed meter was designed using the Internet of Things and configuration software. In the system, the upper computer software adopted the Kingview software, the lower computer took the STM32F429IGT and CC2530 as the core controllers, and ZigBee was selected for data transmission to build the wireless sensor network. The acquisition of field status information and the sending of control instructions were realized through the sensor nodes constructed by the CC2530 core controller. The data was sent to the coordinator node in real-time through the wireless sensor network. The coordinator node realized the bidirectional transmission of data with Kingview and the upper computer control instructions forwarding using the ASCII protocol The host computer monitoring and management software was developed based on configuration software to realize real-time data monitoring, access database storage, fault alarm, control command sending and other functions. The experimental results showed that the detection accuracy of the system for the seeding amount and missed seeding amount was 94.3% and 95.6%, respectively, which could realize the monitoring of the primary working status of the seed meter. The system realized effective data transmission and data remote wireless transmission function, which provided sufficient theoretical and data support for the performance optimization of the seed meter, and laid a good foundation for the visualization and intelligence of information data.

Stateful Function as a Service at the Edge

In FaaS, users invoke remote functions, which encapsulate service(s). These functions typically need to remotely access a persistent state via external services: this makes the paradigm less attractive in edge systems, especially for IoT applications, due to the increased delay and outbound traffic. We propose to generalize the FaaS paradigm by allowing functions to alternate between remote-state and local-state phases, depending on internal and external conditions, and dedicating a container with persistent memory to functions when in a local-state phase. We present initial results showing that this simple yet powerful pattern allows to better utilize the available resources, which are scarce on edge nodes, while significantly reducing tail latencies, which is key to enable many new applications based on real-time ML, e.g., in smart vehicles and smart factory scenarios

Cover Picture

Long‐range olefin isomerization could lead to the remote functionalization of hydrocarbon chains, which is advantageous with regards to atom‐, step‐, and redox economy. Herein, a Pd‐catalyzed long‐range olefin isomerization of aryl olefins was developed without the common usage of special ligands or co‐catalyst. The isomerization could be generally achieved in good yields for aryl olefins with different carbon chain lengths (up to 15 units) or different substituents on the phenyl ring. The mechanistic studies showed that the isomerization proceeds through a 1,2‐hydrogen shift. More details are discussed in the article by Zhang et al. on page 2269–2275.image

Zincate‐Mediated Remote Functionalisation of p‐Iodobenzyl Derivatives Through Metallotropy in 2‐Methyltetrahydrofuran as Key Solvent

Abstract2‐MeTHF (2‐methyltetrahydrofuran) promotes the zincate‐mediated remote functionalisation of p‐iodobenzyl derivatives through metallotropy with a broad scope. This biosourced solvent remarkably impacted all the key elementary steps involved in the tandem reaction. The method tolerates a wide range of sensitive functionalities within the substrates as well as enolisable and activated or deactivated aromatic aldehydes as reaction partners. A challenging benzyl naphthalene derivative was even reacted through an original dearomatisation/rearomatisation/metallotropy chain.magnified image

A 36 cm robotic optical telescope: Equipment and software

The paper describes an optical telescope system and control software for robotic observation of space debris. The telescope has a main aperture of 355 mm, adopts the optical design scheme of primary focus with a large field of view, and is equipped with a highly sensitive 4 K sCMOS camera to achieve a large field of view of 2.6° × 2.6°. The telescope is equipped with an environmental monitoring system and a highly reliable dome to ensure the safe operation of the telescope. The control software of the telescope consists of two parts. One part is deployed locally to comprehensively schedule the robotic operation of various equipment of the telescope system, and the other part is deployed remotely to realize the functions of equipment status monitoring, networking scheduling, remote control, and data management. At present, four telescopes have been deployed in Korla, Xinjiang, China to form a telescope array, basically realizing the remote “unattended” observation of space debris.