Reliable Properties Research Articles

Fatigue life enhancement of foreign object impacted railway axle EA4T steel with surface shot peening

This study investigates the effects of surface reinforcement and foreign object damage (FOD) on the fatigue property of the EA4T alloy steel used for high-speed railway axles. The results of characterization of its microstructure revealed the evolution of the shot-peening-reinforced layers and the craters induced by the impact. Moreover, the results of reconstruction of the residual stress field at the crater, obtained by combining the Johnson–Cook model with the temperature field difference setting method, showed the development of residual tensile stress at the rim of the impact crater and residual compressive stress at its bottom. The fatigue test results demonstrated that surface reinforcing can effectively enhance the fatigue resistance of FOD induced specimens. Probabilistic fatigue SN curves constructed by an improved backward statistical inference method can be used to derive reliable fatigue properties. The fatigue-induced fracture showed that the combination of competing effects of stress concentration, residual stress, micro damage and microstructure were the main fatigue failure mechanisms of axles subject to foreign object damage. The curves of the crack growth rate predicted by the iLAPS model indicated that the service life of the damaged axle can be adequately calculated based on its static tensile properties.

Uniform stain pattern of robust MOF-mediated probe for flexible paper-based colorimetric sensing toward environmental pesticide exposure

Excessive residual pesticides have raised overall environmental damage and health hazard issues, thus the development of facile and sensitive means for pesticide monitoring in different environmental field is desperately needed but challenging. In this work, a flexible paper-based colorimetry beating coffee-ring effect is achieved toward sensing environmental pesticide exposure in user-friendly mode. First, to circumvent poor performance of biomolecules, robust probe is designed by imprinting metal-organic frameworks (MOFs) with specific pockets, enabling to provide “key-lock” identification and sensitive quantitative information under harsh environment. Innovatively, integrating the MOF-mediated probe with filter paper, a well-distributed sensing interface is harvested to reduce colorimetric signal fluctuation for reliable detection properties, which is ascribed to superior wetting behavior of filter paper for avoiding ring-like deposit formation. Additionally, the uniform profile is simulated by Fluent numerical software. Further exploiting smartphone-assisted image acquisition and self-adaptive signal model, the simple-to-perform system exhibits good accuracy toward ppb-level thiacloprid free of colored background interference. A low limit of detection of 0.04 μM thiacloprid (corresponding to 0.01 μg g−1 by weight) is achieved. Moreover, it allows for in-filed monitoring thiacloprid exposure in agricultural wastewater, soil, fresh vegetables with satisfactory recoveries ranging from 92.7 % to 109.0 %, verifying the broad potential applications for point-of-use tracking of environmental pesticide and eventually bringing benefits to ecosystem protection in resource-deficient settings.

Highlight Removal of Multi-View Facial Images.

Highlight removal is a fundamental and challenging task that has been an active field for decades. Although several methods have recently been improved for facial images, they are typically designed for a single image. This paper presents a lightweight optimization method for removing the specular highlight reflections of multi-view facial images. This is achieved by taking full advantage of the Lambertian consistency, which states that the diffuse component does not vary with the change in the viewing angle, while the specular component changes the behavior. We provide non-negative constraints on light and shading in all directions, rather than normal directions contained in the face, to obtain physically reliable properties. The removal of highlights is further facilitated through the estimation of illumination chromaticity, which is done by employing orthogonal subspace projection. An important practical feature of the proposed method does not require face reflectance priors. A dataset with ground truth for highlight removal of multi-view facial images is captured to quantitatively evaluate the performance of our method. We demonstrate the robustness and accuracy of our method through comparisons to existing methods for removing specular highlights and improvement in applications such as reconstruction.

Experimental investigation of fiber content and length on curing time‐dependent mode‐I fracture behavior and properties of cemented paste backfill and implication to engineering design

AbstractThe inclusion of fiber in cemented paste backfill (CPB) can significantly alter the mechanical response of the CPB body. The intrinsic defects in CPB and the potential dynamic loading condition make it necessary to investigate the fracture properties of fiber‐reinforced CPB (FR‐CPB). The mode‐I fracture behavior and properties are crucial to the successful engineering application of FR‐CPB technology used in underground mines. The contribution of fiber length and content to the evolutive mode‐I fracture behavior and properties of FR‐CPB was examined in this study. The results show that the addition of fiber reduces the prepeak stiffness but improves the mode I fracture toughness (KIc), and the improvement in KIc increases with fiber length. In contrast, the initial increase in fiber content (from 0% to 0.5%) benefits the KIc acquisition, while a further increase in fiber content from 0.5% to 0.75% poses a negative influence on the KIc development. Moreover, with the adoption of the cement hydration model, four predictive functions are proposed to describe the contribution of fiber length and content to the development of fracture properties. In addition, KIc is identified as a more reliable fracture property for assessing the immediate ground support role played by the FR‐CPB structure. The findings are helpful when it comes to the determination of the fiber length and content in FR‐CPB design.

A cellulose-based self-healing composite eutectogel with reversibility and recyclability for multi-sensing

Flexible sensors have been widely applied in wearable devices recently. These devices are prone to abrasion, crack, and accidental damage, which result in function failure or even abandonment aggravating environmental degradation. Therefore, it is a huge challenge to endow the flexible sensors with self-healability, recyclability as well as high mechanical property. Herein, a novel recyclable, highly stretchable, self-healing eutectogel was fabricated by freeze-thaw of polyvinyl alcohol (PVA), gelatin and dialdehyde carboxymethyl cellulose (DCMC) in a deep eutectic solvent (DES) with strain rate, humid and temperature sensing capability. The composite eutectogel consisted of imine bond and hydrogen bond reversible networks, which endowed the eutectogel with faster self-healability, as well as the green and simple recyclability. It performed satisfying tensile strength (up to ∼1.25 MPa) with unexceptionable fracture elongation (∼1400%). By leveraging the DES to inhibit freezing and dehydration, the eutectogel was fabricated with a wide working temperature (−20.9 to 64.1 °C) while its weight and sensing performance remained stable after 30 days in open air. The composite eutectogel sensor manifested reliable mechanical and electrical properties under repetitive deformation operation and sensitive responsiveness to real-time variation of rate, temperature, and humidity, which well mimics human breathing in time. Amazingly, based on the hydrolysis of the imine and hydrogen bonds, the recyclable eutectogels retained vast majority of mechanical strength, adhesion, and conductivity. Compared to most synthetic soft materials, the composite eutectogels provide a promising strategy for the development of sustainable multifunctional soft materials that have high environmental adaptability and practical applications.

Stiffness of Ballastless Railway Embankments Determined by Repetitive Static Plate Load Tests

In the repetitive static plate load test, a plate is loaded in two cycles where the second loading cycle provides a modulus denoted Ev2. When calculating the stiffness of a railway embankment, Young’s modulus is often assumed to be equal to Ev2 throughout the embankment. This approach, however, provides inaccurate results, mainly due to soil nonlinearity and the influence of confinement stress. Currently, there exists no method to account for these aspects to derive reliable deformation properties of embankments. Occasionally, correction factors are applied to Ev2, resulting in crude estimations. In this study, plate load tests were simulated in PLAXIS 2D using the Hardening Soil Model and calibrated against four field tests, conducted on crushed rock-fill sub-ballast. The calibrated soil properties were applied in finite element simulations of railway embankments with ballastless slab-track systems. Based on the results of finite element analyses, a semi-empirical approach is proposed, which considers confinement stress through a hyperbolic stress–strain relationship. Soil properties for compacted rock-fill with particle grading 0–150 mm were assumed through the results of the calibrated finite element analyses and the method was verified against 43 plate load tests. This semi-empirical method is more accurate than assuming a constant Young’s modulus, while maintaining simplicity and ease of use.

Retrieval, Selection, and Evaluation of Chemical Property Data for Assessments of Chemical Emissions, Fate, Hazard, Exposure, and Risks.

Reliable chemical property data are the key to defensible and unbiased assessments of chemical emissions, fate, hazard, exposure, and risks. However, the retrieval, evaluation, and use of reliable chemical property data can often be a formidable challenge for chemical assessors and model users. This comprehensive review provides practical guidance for use of chemical property data in chemical assessments. We assemble available sources for obtaining experimentally derived and in silico predicted property data; we also elaborate strategies for evaluating and curating the obtained property data. We demonstrate that both experimentally derived and in silico predicted property data can be subject to considerable uncertainty and variability. Chemical assessors are encouraged to use property data derived through the harmonization of multiple carefully selected experimental data if a sufficient number of reliable laboratory measurements is available or through the consensus consolidation of predictions from multiple in silico tools if the data pool from laboratory measurements is not adequate.

The B-Score is a novel metric for measuring the true performance of blood pressure estimation models

We aimed to develop and test a novel metric for the relative performance of blood pressure estimation systems (B-Score). The B-Score sets absolute blood pressure estimation model performance in contrast to the dataset the model is tested upon. We calculate the B-Score based on inter- and intrapersonal variabilities within the dataset. To test the B-Score for reliable results and desired properties, we designed generic datasets with differing inter- and intrapersonal blood pressure variability. We then tested the B-Score’s real-world functionality with a small, published dataset and the largest available blood pressure dataset (MIMIC IV). The B-Score demonstrated reliable and desired properties. The real-world test provided allowed the direct comparison of different datasets and revealed insights hidden from absolute performance measures. The B-Score is a functional, novel, and easy to interpret measure of relative blood pressure estimation system performance. It is easily calculated for any dataset and enables the direct comparison of various systems tested on different datasets. We created a metric for direct blood pressure estimation system performance. The B-Score allows researchers to detect promising trends quickly and reliably in the scientific literature. It further allows researchers and engineers to quickly assess and compare performances of various systems and algorithms, even when tested on different datasets.

Spatial pricing of ride-sourcing services in a congested transportation network

We investigate the impacts of spatial pricing for ride-sourcing services in a Stackelberg framework considering traffic congestion. In the lower level, we use combined distribution and assignment approaches to explicitly capture the interactions between drivers’ relocation, riders’ mode choice, and all travelers’ routing decisions. In the upper level, a single transportation network company (TNC) determines spatial pricing strategies to minimize imbalance in a two-sided market. We show the existence of the optimal pricing strategies for locational imbalance minimization, and propose effective algorithms with reliable convergence properties. Furthermore, the optimal pricing is unique and can be solved in a convex reformulation when waiting time is small compared to travel time. We conduct numerical experiments on different scales of transportation networks with different TNC objectives to generate policy insights on how spatial pricing could impact transportation systems.

Predicting the interaction between organic layer and metal substrate through DFTB and electrochemical approach for excellent corrosion protection

Despite the growing interest in dealing with how to control the corrosion behavior of steel alloys via organic corrosion inhibitors (CIs), the adsorption mechanism of CIs has remained less understood with respect to the physical–chemical interactions as well as the self-assembly of organic coatings, which might be the primary sources for excellent electrochemical resistance. For this purpose, a new carbocyclic compound, namely 4-Hydroxy-3-(2-methoxybenzoyl)-2,6-bis(4-methoxylphenyl)-4-(2-methoxyphenyl)cyclohexane-1,1dicarbonitrile (PTC), was synthesized as a sustainable-green corrosion inhibitor for mild steel (MS) in HCl solution in a bid to understand the organic-metal mechanism, the adsorption behavior, and the correlation between charge transfer phenomena and corrosion properties of PTC compound. NMR (1H and 13C) spectroscopy, electrochemical techniques and surface analysis were used to characterize and evaluate the inhibitive performance of PTC compound on the metal substrate. The electrochemical results revealed that the PTC inhibitor exhibited high corrosion resistance with inhibition efficiency reaches 92.86 % at 10−3 M due to the significant growth of organic layer sealing the micro-defects present in corroded metal. Furthermore, thePTC inhibitor showed good performance at all temperatures (303–333 K) studied and maintainedprotective ability at the maximum temperature. Then, the protective layer assembled by the adsorption of PTC inhibitor presents robust protection and reliable corrosion stability. Multi-level theoretical calculations based on density functional theory (DFT), density functional based tight-binding (DFTB) and molecular dynamic (MD) simulations were performed to explore the corrosion protection mechanism activated by the presence of PTC inhibitor. As a result, the PTC-surface interactions are mainly dominated by the formation of strong covalent bonds such as N–Fe and O–Fe in the parallel adsorption geometries, in which the formation of the organic layer is consistent with improved charge transfer behavior. Thus, the PTC molecule was preferentially adsorbed through polar functional groups and exhibits high adsorption energy (–6.43 eV), resulting from self-assembly triggered by an organic-metal interaction. This was confirmed experimentally by the results of electrochemical assessments, which showed that reliable and excellent barrier properties were provided for more than 72 h owing to the significant role of functional groups in the π–π interactions of adsorbed PTC molecule. Finally, the computational perspectives provide a profound explanation for the interfacial mechanism of the PTC molecule and show a good correlation with the experimental observations.

Effect of Ag coating on the oxidation resistance, sintering properties, and migration resistance of Cu particles

Ag-coated Cu particles (Cu@Ag particles) are highly anticipated bimetallic materials with wide electronic applications. However, it is still crucially challenging to obtain well-covered Ag shells and facilitate the synthetic process, and the sintering/migration behaviors of Cu@Ag particles are also poorly understood. In this study, we develop a facile Ag coating method for Cu@Ag particles with the assistance of double complexing agents. Electrochemical analysis reveals that the complexing effect can effectively reduce the potential difference of the Cu-Ag replacement reaction, and thereby improve the coating quality. Cu@Ag particles with compact and uniform Ag shells are obtained, with Ag contents as low as ~10 at%. The as-prepared Cu@Ag particles show significantly improved oxidation resistance and reliable sintering property. Moreover, the Cu@Ag particles exhibit superior ion migration resistance even better than both Cu and Ag particles under an oxygen-containing environment. The results could provide helpful basis for understanding the synthesis, sintering and migration processes of Cu@Ag particles. The comprehensive performance of Cu@Ag particles makes them a promising interconnected material in future electronic industry.

Calculation of Gas-phase Standard Formation Enthalpy via Ring-Preserved Connectivity-Based Hierarchy and Automatic Bond Separation Reaction Platform

Bond separation reaction (BSR) is an effective scheme to derive reliable thermochemical properties by systematic error cancellation, while some challenges exist before its wide applications. The traditional BSR schemes are less feasible to cyclic molecules, and automatic BSR programs are not yet fully developed, unbeneficial to maintain the reliability and efficiency of BSR. Herein, we propose an improved scheme of BSR, the Ring-Preserved Connectivity-Based Hierarchy (RCBH) scheme, to enhance the predicted accuracy of gas-phase standard enthalpy of formation (EOF) by quantum chemical calculations. The accuracy and time–cost of RCBH scheme are tested at various DFT levels, involving 12 functionals and 6 basis sets, with samples covering 250 cyclic organic molecules. The superiority of RCBH in calculating EOF is verified, with M062X/6-31 + G(2df,p) recommended as the most cost-effective DFT level, which can approach the accuracy of G4 with only 4% CPU-time of G4. The EOFs calculated by M062X/6-31 + G(2df,p) with RCBH correction are highly consistent with the experimental measurements, with a MAE of 1.1 kcal/mol. We also develop an automated BSR software package, Automatic Bond Separation Reaction Platform (ABSRP), feasible for all categories of organic molecules. The RCBH scheme and ABSRP are expected to be used in calculating other thermochemical properties of extensive categories of neutral organic molecules, with high accuracy while low computational cost.

First-principles calculations on the electronic structure and thermoelectric properties of quaternary Heusler compounds: LiScPtSi and LiScPdGe

This research work explores the two quaternary Heusler compounds within the 18-valence electron formalism i.e. LiScPtSi and LiScPdGe as the capable thermoelectric materials in the temperature range of 1200 K. The band structure of these compounds reports the indirect bandgap of 1.08 eV for LiScPtSi and 0.5352 eV for LiScPdGe, also declares as p-type semiconductors. This report presents the structural, electronic, phonon, elastic and mechanical properties for the practical utilization of the materials. The melting point of LiScPtSi and LiScPdGe are calculated as 1561 ± 300 K and 1245 ± 300 K respectively; owing to this fact all the prime thermoelectric properties along with the Figure of Merit (ZT) are calculated in the temperature range of 1200 K. The investigated materials are purely anisotropic with ductile property (can be stretched as wires), dynamically and mechanically stable. In an overview of thermoelectric properties, the Seebeck coefficient and the lattice thermal conductivity at 300 K for LiScPtSi are 1784 μV/K, 39.6 W/mK and for LiScPdGe are 894μV/K, 27.7 W/mK respectively. Nevertheless, the respective maximum Figure of Merit (ZT) is 0.57 and 0.53 at the 1200 K that ensures the materials to be efficient thermoelectric elements in the high-temperature range with reliable material properties. As the materials are first time investigated here in the detailed prospectus; the proposed research work is proficient to be considered in experimental research as well as for energy conversion applications.

"In Vitro" and "In Vivo" Diagnostic Check for the Thermochemistry of Metal-Organic Compounds.

Volatile metal β-diketonates are of interest from both practical and theoretical perspectives (manufacturing of film materials, catalysis, and the nature of metal-ligand bonding). Knowledge of their reliable thermochemical properties is essential for effective applications. However, there is an unacceptable scattering of the available data on the enthalpies of formation. In this work, we proposed "in vitro" and "in vivo" diagnostic tools to verify the available enthalpies of formation in both the crystalline and gaseous states for metal tris-β-diketonates. The "in vitro" procedure involved high-level quantum-chemical calculations and was applied to define a consistent data set on the enthalpies of formation for iron(III) β-diketonates. This data set has provided the basis for "in vivo" structure-property-based diagnostics to evaluate the robustness of the thermochemical data for β-diketonate tris-complexes with metals other than iron.

Role of IGZO thickness for oxygen reservoir control in stacked IGZO/ZrOx layers: Towards reliable, uniform performance of flexible random-access memories

For securing the enhanced properties in ZrOx based RRAMs, the roles of IGZO thickness in the switching window and stability of stacked IGZO/ZrOx RRAM devices are systematically investigated. The physical characteristics of the amorphous crystal structure of IGZO film and the variation of oxygen vacancy with IGZO thickness are validated by glancing angle X-ray diffraction (GAXRD) and X-ray photoelectron spectroscopy (XPS) analysis. The reliable and uniform switching properties for bilayer RRAMs with (92 ± 2) nm IGZO films are obtained as a stable switching up to 103 cycles, ROFF/RON ratio (~102), and retention for 104 s. The improvement in the RRAM performances is interpreted with oxygen vacancy in the IGZO layer, which facilitates the role of oxygen reservoir owing to its oxygen-deficient composition to absorb/discharge oxygen ions. With respect to the switching mechanism, set cycles are governed by a trap-mediated space-charge-limited current (SCLC) conduction. Furthermore, the optimal IGZO thickness-based bilayer IGZO/ZrOx RRAM device on a flexible polyethylene terephthalate (PET) substrate is demonstrated with stable switching up to 103 cycles, ROFF/RON ratio (>10), and retention for 104 s, along with the stable performance under different bending radii. With the scheme of IGZO based oxygen vacancy control, IGZO/ZrOx bilayer-based RRAM devices are expected to be one of viable options for the flexible, wearable, and biomedical applications.

Characterization of the Elastic, Piezoelectric, and Dielectric Properties of Lithium Niobate from 25 °C to 900 °C Using Electrochemical Impedance Spectroscopy Resonance Method.

Lithium niobate (LiNbO) is known for its high Curie temperature, making it an attractive candidate for high-temperature piezoelectric applications (>200 °C); however, the literature suffers from a paucity of reliable material properties data at high temperatures. This paper therefore provides a complete set of elastic and piezoelectric coefficients, as well as complex dielectric constants and the electrical conductivity, for congruent monocrystalline LiNbO from 25 °C to 900 °C at atmospheric pressure. An inverse approach using the electrochemical impedance spectroscopy (EIS) resonance method was used to determine the materials’ coefficients and constants. Single crystal Y-cut and Z-cut samples were used to estimate the twelve coefficients defining the electromechanical coupling of LiNbO. We employed an analytical model inversion to calculate the coefficients based on a linear superposition of nine different bulk acoustic waves (three longitudinal waves and six shear waves), in addition to considering the thermal expansion of the crystal. The results are reported and compared with those of other studies for which the literature has available values. The dominant piezoelectric stress constant was found to be , which remained virtually constant between 25 °C and 600 °C; thereafter, it decreased by approximately 10% between 600 °C and 900 °C. The elastic stiffness coefficients , , and all decreased as the temperature increased. The two dielectric constants and increased exponentially as a function of temperature.

Fabrication and characterization of biodegradable Zn scaffold by vacuum heating-press sintering for bone repair.

Bone repair materials with excellent mechanical properties are highly desirable, especially in load-bearing sits. However, the currently used ceramic- and polymer-based ones mainly show poor mechanical properties. Recently, biodegradable metals have attracted extensive attention due to their reliable mechanical strength and degradability. As biodegradable metals, zinc-based materials are promising due to their suitable degradation rate and good biocompatibility. Here, we fabricated biodegradable porous Zn scaffolds with relatively high mechanical properties by vacuum heating-press sintering using NaCl particles as space holders. The microstructure, actual porosity, compressive mechanical properties, in vitro degradation behavior and the vitality of osteoblasts of porous Zn scaffolds were tested and investigated. The results show the porosities of the prepared porous Zn scaffolds are ranging from 11.3% to 63.3%, and the pore sizes are similar to the size range of the screened NaCl particles (200-500μm). Compressive yield strength of 14.2-73.7MPa and compressive elastic modulus of 1.9-6.7GPa are shown on porous Zn scaffolds, some of which approach to that of cancellous bone (2-12MPa and 0.1-5GPa). Compared to bulk Zn, although the porous structures cause a partial loss of strength, the reliable mechanical properties are still retained. In addition, the porous structures not only greatly increase the degradation rate, but also promote the proliferation of osteoblasts. Based on these results, biodegradable porous Zn scaffolds (porosity in the 40%-50%) fabricated by vacuum heating-press sintering method show high application potential for clinical bone repair.

Effect of polycaprolactone impregnation on the properties of calcium silicate scaffolds fabricated by 3D printing

Calcium silicate (CS) is a suitable substrate for bone tissue engineering because it can provide bioactive ions like Si4+ and Ca2+ to promote bone regeneration. However, the rapid degradation of CS leads to pH problems and does not match the rate of osteogenesis. The 3D printed CS scaffolds were immersed in Polycaprolactone (PCL) solution to obtain PCL-coated scaffolds with improved mechanical and biological properties. Finite element method (FEM) analysis found that PCL impregnation has the effect of stress shielding and defect healing, effectively improving the mechanical properties of CS porous scaffolds. The degradation rate of PCL-coated scaffolds was significantly slowed down in Tris buffer. After 4 weeks of degradation, the compressive strength of PCL-coated scaffolds remained at 23.34 MPa, maintaining reliable mechanical properties. PCL coating significantly reduced the degradation rate of CS scaffolds, and the pH value and Si ion concentration of Dulbecco's modified Eagle's medium (DMEM) soaked by PCL-coated scaffolds were more favorable for cell survival. The results show that PCL-coated scaffolds enhance cell proliferation and osteogenic differentiation, demonstrating the potential applicability of bone tissue engineering applications.

Investigating Mechanical Behaviours of PDMS Films under Cyclic Loading.

Polydimethylsiloxane (PDMS) is widely utilised as a substrate for wearable (stretchable) electronics where high fatigue resistance is required. Cyclic loadings cause the rearrangement of the basic molecular structure of polymer chains, which leads to changes in the mechanical properties of the PDMS structure. Accordingly, it is necessary to investigate reliable mechanical properties of PDMS considering both monotonic and cyclic loading conditions. This study aims to present the mechanical properties of PDMS films against both monotonic and cyclic loading. The effects of certain parameters, such as film thickness and magnitude of tensile strain, on mechanical properties are also investigated. The test results show that PDMS films have a constant monotonic elastic modulus regardless of the influence of thickness and tensile loading, whereas a cyclic elastic modulus changes depending on experimental parameters. Several material parameters, such as neo-Hookean, Mooney–Rivlin, the third-order Ogden model, and Yeoh, are defined to mimic the stress–strain behaviours of the PDMS films. Among them, it is confirmed that the third-order Ogden model is best suited for simulating the PDMS films over the entire tensile test range. This research makes contributions not only to understanding the mechanical behaviour of the PDMS films between the monotonic and the cycle loadings, but also through providing trustworthy hyperelastic material coefficients that enable the evaluation of the structural integrity of the PDMS films using the finite element technique.

Synthesis of pyrazole tethered oxadiazole and their analogs as potent antioxidant agents

AbstractPreparation of organic compounds in environmental favor media always a fresh tool in the synthetic research. If those prepared compounds may possess therapeutically potentiality, then it called as efficient research. Herein, we report the 12 new oxadiazole linked carboxamide pyrazole substances have been synthesized and screened for their free radical scavenging activity by using hydrogen peroxide (H2O2), nitric oxide (N2O), and diphenyl picryl hydrazide (DPPH) methods. All the compounds displayed reliable biological properties. Among them, compound 8f hold high antioxidant activity may be due to the presence of methoxy group at para position of benzene ring. From the synthetic point of view, this is the novel environment favor method for the synthesis of pyrazole linked oxadiazoles, and the biological results of these compounds may stand as a referee for further development of biologically active pyrazole tethered oxadiazoles.