The quality and reliability of wind turbine blades, as core components of wind turbines, are crucial for the operational safety of the entire system. Carbon fiber is the primary material for wind turbine blades. However, during the manufacturing process, manual intervention inevitably introduces minor defects, which can lead to crack propagation under complex working conditions. Due to limited understanding and measurement capabilities of the input variables of structural systems, the distribution parameters of these variables often exhibit uncertainty. Therefore, it is essential to assess the impact of distribution parameter uncertainty on the fatigue performance of carbon-fiber structures with initial cracks and quickly identify the key distribution parameters affecting their reliability through global sensitivity analysis. This paper proposes a sensitivity analysis method based on surrogate sampling and the Kriging model to address the computational challenges and engineering application difficulties in distribution parameter sensitivity analysis. First, fatigue tests were conducted on carbon-fiber structures with initial cracks to study the dispersion of their fatigue life under different initial crack lengths. Next, based on the Hashin fatigue failure criterion, a simulation analysis method for the fatigue cumulative damage life of cracked carbon-fiber structures was proposed. By introducing uncertainty parameters into the simulation model, a training sample set was obtained, and a Kriging model describing the relationship between distribution parameters and fatigue life was established. Finally, an efficient input variable sampling method using the surrogate sampling probability density function was introduced, and a Sobol sensitivity analysis method based on surrogate sampling and the Kriging model was proposed. The results show that this method significantly reduces the computational burden of distribution parameter sensitivity analysis while ensuring computational accuracy.